Microtubules pp 442-454 | Cite as

Post-Script and Outlook

  • Pierre Dustin

Abstract

At the end of this survey of MT research — by necessity incomplete, as several hundred papers on MT are published each year and only a fraction of these could be quoted — the task of considering in this last chapter the problems which remain to be solved and some future fields for tubulin and MT research is by no means easy. MT are present in all eukaryotes, and since eons have been put to use by the cells in many functions — skeletal supports, guidance tracks, traction or restraining ropes, or constituents of complex organelles such as flagella, cilia and axonemes. Tubulins are highly conserved proteins, comparable in this aspect to the histones, but have evidently undergone mutations since the origin of the first “prototubulin” molecule — perhaps a billion years ago — from which the various α and β tubulins diverged.

Keywords

Milling Fibril Triphosphate Copolymerization Diphosphate 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • Pierre Dustin
    • 1
  1. 1.Laboratoires d’Anatomie Pathologique et de Microscopie ElectroniqueUniversité Libre de BruxellesBruxellesBelgium

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