The Use of Timolol in Reducing the Incidence of Supraventricular Arrhythmias After Coronary Artery Bypass Surgery
A review of 13 publications dealing with the development of supraventricular arrhythmias after coronary artery bypass graft yielded a mean overall incidence of 27.5% (Table 1) [1–12]. In the U.S.A. some 100000 such operations are performed yearly  and something on the order of 30000 patients develop this postoperative complication. These arrhythmias often require cardioversion and invariably drug therapy. They can cause a drop in arterial pressure which could have deleterious effects on graft haemodynamics and subsequent long-term patency.
KeywordsPlacebo Cardiol Propranolol Digoxin Timolol
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- 2.Rose MR, GlassmanE, Spencer FC (1975) Arrhythmias following cardiac surgery: relation to serum digoxin levels. Am Heart J 89 (3): 288–294Google Scholar
- 4.BoudoulasH, Lewis RP, SnyserGL, Karayannocos P, Vasko JS (1979) Beneficial effects of continuation of propranolol through coronary bypass surgery. Clin Cardiol 2: 87–91Google Scholar
- 10.Csicsko JF, Schatzlein MH, King RD (1981) Immediate postoperative digitalisation in the prophylaxis of supraventricular arrhythmias following coronary artery bypass. Thorac Cardiovas Surg 81: 419–422Google Scholar
- 13.Roberts WC, Mason DT, Engle MA, Cohn LM (1982) Cardiology 1982. Yorke Medical p69Google Scholar
- 14.Mills SA, Poole GV, Breyer RH, Holliday RM, Lavender SW, Blanton KR, Hudspeth AS, Johnston FR, Cordell AR (1983) Digoxin and propranolol in the prophylaxis of dysrhythmias after coronary artery bypass grafting. Circulation 68 (Suppl 11): 222Google Scholar