Skip to main content

Infektiöse Endokarditis

  • Chapter
Kardiologie

Zusammenfassung

Der Gebrauch des Terminus „infektiöse Endokarditis“ spiegelt die Tatsache wider, daß man nicht länger eine akute sowie eine subakute Form als getrennte Krankheitsbilder betrachten kann. Auch schließt das Erregerspektrum nicht mehr nur Bakterien ein. Die infektiöse Endokarditis erscheint heute wesentlich vielgestaltiger. Als Erreger kommen Bakterien, Rickettsien und Pilze (nur äußerst selten Viren oder Parasiten) in Betracht. Man findet hinsichtlich des Verlaufs vom chronischen bis zum hyperakuten Typ alle Übergänge. Dies läßt jeden Versuch, die infektiöse Endokarditis in zwei Verlaufsformen einzuteilen, scheitern. In Abhängigkeit von seiner Virulenz sowie der Abwehrlage des Wirtorganismus kann ein und derselbe Erreger eine akute oder subakute Endokarditis verursachen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Anderson DJ, Bulkley BH, Hutchins GM: A clinicopathologic study of prosthetic valve endocarditis in 22patients: Morphologic basis for diagnosis and therapy. Am Heart J 1977; 94: 325.

    PubMed  CAS  Google Scholar 

  • Arnett EN, Roberts WC: Prosthetic valve endocarditis: Clinicopathologic analysis of 22 necropsy patients with comparison of observations in 74 necropsy patients with active infective endocarditis involving natural left-sided cardiac valves. Am J Cardiol 1976; 38: 281.

    PubMed  CAS  Google Scholar 

  • Cates JE, Christie RV: Subacute bacterial andocarditis: A review of 442 patients treated in 14 centres appointed by the Penicillin Trials Committee of the Medical Research Council. Q J Med 1951; 20: 93.

    Google Scholar 

  • Kaplan EL & others: AHA Cooperative Study of the Occurrence of Infective Endocarditis. (Abstract.) Circulation 1977; 56(4-Part2): III-39.

    Google Scholar 

  • Mills J, Drew D:Serratia marcescens endocarditis: A regional illness associated with intravenous drug abuse. Ann Intern Med 1976; 84: 29.

    PubMed  CAS  Google Scholar 

  • Weinstein L, Schlesinger JJ: Pathoanatomic, pathophysiologic, and clinical correlations in endocarditis. (2 parts.) N Engl J Med 1974; 291:832,1122.

    PubMed  CAS  Google Scholar 

  • Wilson WR, Washington JA II: Infective endocarditis: A changing spectrum: Mayo Clin Proc 1977; 52: 254.

    PubMed  CAS  Google Scholar 

  • Alpert JS & others: Pathogenesis of Osier’s nodes.Ann Intern Med 1976; 85: 471.

    PubMed  CAS  Google Scholar 

  • Banks T, Fletcher R, Ali N: Infective endocarditis in heroin addicts. Am J Med 1973; 55: 444.

    PubMed  CAS  Google Scholar 

  • Bayer AS & others: Circulating immune complexes in infective endocarditis. N Engl J Med 1976; 295: 1500.

    PubMed  CAS  Google Scholar 

  • Berger M & others: Two-dimensional echocardiographic findings in right-sided infective endocarditis. Circulation 1980; 61: 855.

    PubMed  CAS  Google Scholar 

  • Botvinick EH & others: Echocardiographic demonstration of early mitral valve closure in severe aortic insufficiency: Its clinical implications. Circulation 1975; 51: 836.

    PubMed  CAS  Google Scholar 

  • Casey JI, Miller MH: Infective endocarditis. (Part2.) Am Heart J 1978 96: 263.

    PubMed  CAS  Google Scholar 

  • Cliff MM, Soulen RL, Finestone AJ: Mycotic aneurysms: A challenge and a clue. Arch Intern Med 1970; 126: 977.

    PubMed  CAS  Google Scholar 

  • Chandraratna PAN, Aronow WS: Spectrum of echocardiographic findings in tricuspid valve endocarditis. Br Heart J 1979; 42: 528.

    PubMed  CAS  Google Scholar 

  • Cohen PS, Maguire JH, Weinstein L: Infective endocarditis caused by gram-negative bacteria: A rewiev of the literature, 1945–1977. Prog Cardiovasc Dis 1980; 22: 205

    PubMed  CAS  Google Scholar 

  • Corrigall D & others: Mitral valve prolapse and infective endocarditis. Am J Med 1977; 63: 215.

    PubMed  CAS  Google Scholar 

  • DeMaria AN & others: Echography and phonography of acute aortic regurgitation in bacterial endocarditis. Ann Intern Med 1975; 82:329.

    PubMed  CAS  Google Scholar 

  • Dismukas WE & others: Prosthetic valve endocarditis: Analysis of 38 cases. Circulation 1973; 48: 365.

    Google Scholar 

  • Dreyer NP, Fields BN: Heroin-associated infective endocarditis: Report of 28 cases. Ann Intern Med 1973; 78: 699.

    PubMed  CAS  Google Scholar 

  • Dzindzio BS & others: Isolated gonococcal pulmonary valve endocarditis: Diagnosis by echocardiography. Circulation 1979; 59:1319.

    PubMed  CAS  Google Scholar 

  • Foster MT Jr, Harrison HE: Bacterial endocarditis. Chapter 8 in: Infectious Diseases. Marr JJ (editor). Little, Brown, 1973.

    Google Scholar 

  • Hall B, Dowling HF: Negative blood cultures in bacterial endocarditis: A decade’s experience. Med Clin North Am 1966; 50:159.

    PubMed  CAS  Google Scholar 

  • Hirschfeld DS, Schiller N: Localization of aortic valve vegetations by echocardiography. Circulation 1976; 53: 280.

    PubMed  CAS  Google Scholar 

  • Hutter AM, Moellering RC: Assessment of the patient with suspected endocarditis. JAMA 1976; 235:1603.

    PubMed  Google Scholar 

  • Iannini PB & others: Candida precipitins as a diagnostic aid in Candida endocarditis.JAMA 1976; 236: 2518.

    Google Scholar 

  • Jacoby GA, Swartz MN: Current concepts: Fever of undetermined origin.N Engl J Med 1973; 289:1407.

    PubMed  CAS  Google Scholar 

  • Johnson DH, Rosenthal A, Nadas AS: A forty-year review of bacterial endocarditis in infancy and childhood. Circulation 1975; 51: 581.

    PubMed  CAS  Google Scholar 

  • Kaplan EL & others: A collaborative study of infective endocarditis in the 1970’s: Emphasis on infections in patients who have undergone cardiovascular surgery. Circulation 1979; 59: 327.

    PubMed  CAS  Google Scholar 

  • Kaye D (editor): Infective Endocarditis. University Park Press, 1976.

    Google Scholar 

  • Kimbrough RC & others: Q fever endocarditis in the United States. Ann Intern Med 1979; 91: 400.

    PubMed  Google Scholar 

  • Lachman AS & others: Infective endocarditis in the billowing mitral leaflet syndrome. Br Heart J 1975; 37: 326.

    PubMed  CAS  Google Scholar 

  • Mann T & others: Assessing the hemodynamic severity of acute aortic regurgitation due to infective endocarditis. N Engl J Med 1975; 293: 108.

    PubMed  CAS  Google Scholar 

  • Mills J, Drew D: Serratia marcescens endocarditis: A regional illness associated with intravenous drug abuse. Ann Intern Med 1976; 84: 29.

    PubMed  CAS  Google Scholar 

  • Mintz GS & others: Comparison of two-dimensional and m-mode echocardiography in the evaluation of patients with infective endocarditis. Am J Cardiol 1979; 43: 738.

    PubMed  CAS  Google Scholar 

  • Murray BE, Karchmer AW, Moellering RC Jr: Diphtheroid prosthetic valve endocarditis: A study of clinical features and infecting organisms.Am J Med 1980 69: 838.

    PubMed  CAS  Google Scholar 

  • Musher DM, McKenzie SO: Infections due to Staphylococcus aureus. Medicine (Baltimore) 1977; 56: 383.

    CAS  Google Scholar 

  • Nastro IJ, Finegold SM: Endocarditis due to anaerobic gramnegative bacilli. Am J Med 1973; 54: 481.

    Google Scholar 

  • Osier W: Chronic infectious endocarditis. Q J Med 1909; 2: 219.

    Google Scholar 

  • Perez GO, Rothfield N, Williams RC: Immune-complex nephritis in bacterial endocarditis. Arch Intern Med 1976; 136: 334.

    PubMed  CAS  Google Scholar 

  • Pesanti EL, Smith IM: Infective endocarditis with negative blood cultures: An analysis of 52 cases. Am J Med 1979; 66: 43.

    PubMed  CAS  Google Scholar 

  • Pruitt AA & others: Neurologic complications of bacterial endocarditis. Medicine 1978; 57: 329.

    PubMed  CAS  Google Scholar 

  • Scheld WM, Sande MA: Endocarditis and intravascular infections. Chap 51, p653, in: Principles and Practice of Infectious Diseases. Vol 1. Mandell GL, Douglas RG Jr, Bennett JE (editors). Wiley, 1979.

    Google Scholar 

  • Seelig MS & others: Candida endocarditis after cardiac surgery: Clues to earlier detection. J Thorac Cardiovasc Surg 1973; 65: 583.

    PubMed  CAS  Google Scholar 

  • Slaughter L, Morris JE, Starr A: Prosthetic valvular endocarditis: A 12-year review. Circulation 1973; 47:1319.

    PubMed  CAS  Google Scholar 

  • Stafford A & others: Diagnostic shelf: Serial echocardiographic appearance of healing bacterial vegetations. Am J Cardiol 1979; 44:754.

    PubMed  CAS  Google Scholar 

  • Turck WPG & others: Chronic Q fever. Q J Med 1976; 45:193.

    PubMed  CAS  Google Scholar 

  • Wann LS & others: Comparison of M-mode and cross-sectional echocardiography in infective endocarditis. Circulation 1979; 60: 728.

    PubMed  CAS  Google Scholar 

  • Watanakunakorn C: Prosthetic valve infective endocarditis. Prog Cardiovasc Dis 1979; 22:181.

    PubMed  CAS  Google Scholar 

  • Watanakunakorn C, Tan JS, Phair JP: Some salient features of Staphylococcus aureus endocarditis. Am J Med 1973; 54: 473.

    PubMed  CAS  Google Scholar 

  • Welton DE & others: Recurrent infective endocarditis: Analysis of predisposing factors and clinical features. Am J Med 1979; 66: 932.

    PubMed  CAS  Google Scholar 

  • Welton DE & others: Value and safety of cardiac catheterization during active infective endocarditis. Am J Cardiol 1979; 44: 1306.

    PubMed  CAS  Google Scholar 

  • Wise JR Jr, Oakley CM, Goodwin JF: Acute aortic regurgitation in patients with infective endocarditis: The distinctive clinical features and the role of premature mitral valve closure. J Maine Med Assoc 1972; 63: 273.

    PubMed  Google Scholar 

  • Abrams A & others: Single or combination therapy of staphylococcal endocarditis in intravenous drug abusers. Ann Intern Med 1979; 90: 789.

    PubMed  CAS  Google Scholar 

  • AHA Committee Report: Prevention of bacterial endocarditis. Circulation 1977; 56:139A.

    Google Scholar 

  • Appel GB, Neu HC: Gentamicin in 1978. Ann Intern Med 1978; 89: 528.

    PubMed  CAS  Google Scholar 

  • Appel GB, Neu HC: The nephrotoxicity of antimicrobial agents. (3 parts.) N Engl J Med 1977; 296: 633, 722,784.

    Google Scholar 

  • Arnett EN, Roberts WC: Prosthetic valve endocarditis: Clinicopathologic analysis of 22 necropsy patients with comparison of observations in 74 necropsy patients with active infective endocarditis involving natural left-sided cardiac valves. Am J Cardiol 1976; 38: 281.

    PubMed  CAS  Google Scholar 

  • Barratt-Boyes BG & others: Homograft valves. Med J Aust 1972; 2 (Suppl 1): 38.

    PubMed  Google Scholar 

  • Beeson PB, McDermott W (editors): Textbook of Medicine, 14th ed. Saunders, 1974.

    Google Scholar 

  • Bennett JE: Flucytosine. Ann Intern Med 1977; 89: 319.

    Google Scholar 

  • Bennett WM & others: Guidelines for drug therapy in renal failure. Ann Intern Med 1977; 86: 754.

    PubMed  CAS  Google Scholar 

  • Brewer NS: The aminoglycosides: Streptomycin, kanamycin, gentamicin, tobramycin, amikacin, neomycin.Mayo Clin Proc 1977; 52: 675.

    PubMed  CAS  Google Scholar 

  • Cook FV, Farrar WE: Vancomycin revisited: Ann Intern Med 1978; 88: 813.

    PubMed  CAS  Google Scholar 

  • Delgado DG, Cobbs CG: Infections of prosthetic valves and intravascular devices. Chap 52, p 690, in: Principles and Practice of Infectious Diseases. Vol 1. Mandell GL, Douglas RG Jr, Bennett JE (editors). Wiley, 1979.

    Google Scholar 

  • Durack DT: Prophylaxis of infective endocarditis. Chap 53, p701, in: Principles and Practice of Infectious Diseases. Vol 1. Mandell GL, Douglas RG Jr, Bennett JE (editors). Wiley, 1979.

    Google Scholar 

  • Galgiani JN & others: Bacteroidesfragilis endocarditis, bacteremia and other infections treated with oral or intravenous metronidazole. Am J Med 1978; 65: 284.

    PubMed  CAS  Google Scholar 

  • Geraci JE & others: Haemophilus endocarditis: Report of 14patients. Mayo Clin Proc 1977; 52: 209.

    PubMed  CAS  Google Scholar 

  • Green GR, Peters GA, Geraci JE: Treatment of bacterial endocarditis in patients with penicillin hypersensitivity. Ann Intern Med 1967; 67: 235.

    PubMed  CAS  Google Scholar 

  • Hermans PE: Antifungal agents used for deep-seated mycotic infections. Mayo Clin Proc 1977; 52: 687.

    PubMed  CAS  Google Scholar 

  • Hermans PE: General principles of antimicrobial therapy. Mayo Clin Proc 1977; 52: 603.

    PubMed  CAS  Google Scholar 

  • Hook EW III, Johnson WD Jr: Vancomycin therapy of bacterial endocarditis. Am J Med 1978; 65: 411.

    PubMed  Google Scholar 

  • Jawetz E: Anti-infective chemotherapeutic and antibiotic agents. Chapter 28 in: Current Medical Diagnosis & Treatment 1981. Krupp MA, Chatton MJ (editors). Lange, 1981.

    Google Scholar 

  • Jawetz E: Synergism and antagonism among antimicrobial drugs: A personal perspective. West J Med 1975; 123: 87.

    PubMed  CAS  Google Scholar 

  • Jawetz E, Sonne M: Penicillin-streptomycin treatment of enterococcal endocarditis. N Engl J Med 1966; 274: 710.

    PubMed  CAS  Google Scholar 

  • Karchmer AW & others: Late prosthetic valve endocarditis: Clinical features influencing therapy. Am J Med 1978; 64:199.

    PubMed  CAS  Google Scholar 

  • Kaye D: Antibiotic treatment of streptococcal endocarditis. Am J Med 1980; 69: 650.

    PubMed  CAS  Google Scholar 

  • Kumin GD: Clinical nephrotoxicity of tobramycin and gentamicin: A prospective study. JAMA 1980; 244:1808.

    PubMed  CAS  Google Scholar 

  • Leonard JM, McGee ZA, Alford RH: Gentamicin- resistant bacillary infection: Clinical features and amikacin therapy. Arch Intern Med 1978; 138: 201.

    PubMed  CAS  Google Scholar 

  • Lerner PI, Weinstein L: Infective endocarditis in the antibiotic era. (4 parts.) N Engl J Med 1966; 274:159,199, 323,388.

    Google Scholar 

  • Lowes JA & others: Ten years of infective endocarditis at St. Bartholomew’s Hospital: Analysis of clinical features and treatment in relation to prognosis and mortality. Lancet 1980; 1:133.

    PubMed  CAS  Google Scholar 

  • McAnulty JH, Rahimtoola SH: Surgery for infective endocarditis. JAMA 1979; 242: 77.

    PubMed  CAS  Google Scholar 

  • Masur H, Johnson WD: Prosthetic valve endocarditis. J Thorac Cardiovasc Surg 1980; 80: 31.

    PubMed  CAS  Google Scholar 

  • Medoff G, Kobayashi GS: Strategies in the treatment of systemic fungal infections. N Engl J Med 1980; 302:145.

    PubMed  CAS  Google Scholar 

  • Menda KB, Gorbach SL: Favorable experience with bacterial endocarditis in heroin addicts. Ann Intern Med 1973; 78: 25.

    PubMed  CAS  Google Scholar 

  • Mills J, Utley J, Abbott J: Heart failure in infective endocarditis: Predisposing factors, course, and treatment. Chest 1974; 66:151.

    PubMed  CAS  Google Scholar 

  • Moellering RC, Swartz MN: Drug therapy: The newer cephalosporins. N Engl J Med 1976; 294: 24.

    PubMed  CAS  Google Scholar 

  • Neu HC: Amoxicillin: Drugs five years later. Ann Intern Med 1979; 90: 356.

    PubMed  CAS  Google Scholar 

  • Ostermiller WE Jr, Dye WS, Weinberg M: Fungal endocarditis following cardiovascular surgery. J Thorac Cardiovasc Surg 1971; 61: 670.

    PubMed  Google Scholar 

  • Parrott JC W & others: The surgical management of bacterial endocarditis: A review. Ann Surg 1976; 183: 289.

    PubMed  CAS  Google Scholar 

  • Parry MF, Neu HC: A comparative study of ticarcillin plus tobramycin versus carbenicillin plus gentamicin for the treatment of serious infections due to gram-negative bacilli. Am J Med 1978; 64: 961.

    PubMed  CAS  Google Scholar 

  • Pelletier LL Jr, Petersdorf RG: Infective endocarditis. Page 801 in: Harrison’s Principles of Internal Medicine. Ghorn GW & others (editors). McGraw-Hill, 1977.

    Google Scholar 

  • Pelletier LL Jr, Petersdorf RG: Infective endocarditis. A review of 125 cases from the University of Washington Hospitals, 1963–72. Medicine 1977; 56: 27.

    Google Scholar 

  • Petersdorf RG: Antimicrobial prophylaxis of bacterial endocarditis: Prudent caution of bacterial overkill? Am J Cardiol 1978; 65: 220.

    CAS  Google Scholar 

  • Pollack AA & others: Amikacin therapy for serious gram-negative infection. JAMA 1977; 237: 562.

    Google Scholar 

  • Rapaport E: The changing role of surgery in the management of infective endocarditis. (Editorial.) Circulation 1978; 58: 598.

    PubMed  CAS  Google Scholar 

  • Reiner N, Gopalakrishna KV, Lerner PI: Enterococcal endocarditis in heroin addicts. JAMA 1976; 235:1861.

    PubMed  CAS  Google Scholar 

  • Reisberg BE: Infective endocarditis in the narcotic addict. Proc Cardiovasc Dis 1979; 22:193.

    CAS  Google Scholar 

  • Richardson JV & others: Treatment of infective endocarditis: A 10-year comparative analysis. Circulation 1978; 58: 589.

    PubMed  CAS  Google Scholar 

  • Rosenblatt JE: Laboratory tests used to guide antimicrobial therapy. Mayo Clin Proc 1977; 52: 611.

    PubMed  CAS  Google Scholar 

  • Rossiter SJ & others: Prosthetic valve endocarditis. J Thorac Cardiovasc Surg 1978; 76: 795.

    PubMed  CAS  Google Scholar 

  • Sande MA, Scheid WM: Combination antibiotic therapy of bacterial endocarditis. Ann Intern Med 1980; 92: 390.

    PubMed  CAS  Google Scholar 

  • Sipes JN, Thompson RL, Hook EW: Prophylaxis of infective endocarditis: A reevaluation. Annu Rev Med 1977; 28: 371.

    PubMed  CAS  Google Scholar 

  • Slaughter L, Morris JE, Starr A: Prosthetic valvular endocarditis: A 12-year review. Circulation 1973; 47:1319.

    PubMed  CAS  Google Scholar 

  • Smith CR & others: Controlled comparison of amikacin and gentamicin. N Engl J Med 1977; 296: 349.

    PubMed  CAS  Google Scholar 

  • Smith CR & others: Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. N Engl J Med 1980; 302:1106.

    PubMed  CAS  Google Scholar 

  • Stein PD, Harken DE, Dexter L: The nature and prevention of prosthetic valve endocarditis. Am Heart J 1966; 71: 393.

    PubMed  CAS  Google Scholar 

  • Stinson EB: Surgical treatment of infective endocarditis. Prog Cardiovasc Dis 1979; 22:145.

    PubMed  CAS  Google Scholar 

  • Sugrue D & others: Antibiotic prophylaxis against infective endocarditis after normal delivery: It is necessary? Br Heart J 1980; 44:499.

    PubMed  CAS  Google Scholar 

  • Thompson RL: The cephalosporins. Mayo Clin Proc 1977; 52: 625.

    PubMed  CAS  Google Scholar 

  • Tumulty PA: Management of bacterial endocarditis. Geriatrics 1967; 22:122.

    PubMed  CAS  Google Scholar 

  • UCLA Conference (John Edwards, monitor): Severe candidal infections: Clinical perspective, immune defense mechanisms, and current concepts of therapy. Ann Intern Med 1978; 89: 91.

    Google Scholar 

  • Van Scoy RE: Prophylactic use of antimicrobial agents. Mayo Clin Proc 1977; 52: 701.

    Google Scholar 

  • Varma MPS, Adgey AAJ, Connolly JF: Chronic Q fever endocarditis. Br Heart J 1980; 43: 695.

    PubMed  CAS  Google Scholar 

  • Vogler WR, Dorney ER, Bridges HA: Bacterial endocarditis: A review of 148 cases, 1948–1960. Am J Med 1962; 32: 910.

    PubMed  CAS  Google Scholar 

  • Watanakunakorn C: Prosthetic valve infective endocarditis. Prog Cardiovasc Dis 1979; 22:181.

    PubMed  CAS  Google Scholar 

  • Westenfelder GO, Paterson PY: Life-threatening infection: Choice of alternate drugs when penicillin cannot be given. JAMA 1969; 210: 845.

    PubMed  CAS  Google Scholar 

  • Wilkowske CJ: The penicillins. Mayo Clin Proc 1977; 52: 616.

    PubMed  CAS  Google Scholar 

  • Wilson WR & others: Cardiac valve replacement in congestive heart failure due to infective endocarditis. Mayo Clin Proc 1979; 54:223.

    PubMed  CAS  Google Scholar 

  • Wilson WR & others: Infective endocarditis: Therapeutic considerations. Am Heart J 1980;100: 689.

    PubMed  CAS  Google Scholar 

  • Wilson WR & others: Prosthetic valve endocarditis. Ann Intern Med 1975; 82:751.

    PubMed  CAS  Google Scholar 

  • Wilson WR & others: Short-term therapy for streptococcal infective endocarditis: Combined intramuscular administration of penicillin and streptomycin. JAMA 1981; 245: 360.

    PubMed  CAS  Google Scholar 

  • Wyse DG, McAnulty JM, Rahimtoola SH: Antibiotic prophylaxis in patients with rheumatic heart disease and prosthetic devices. Clin Cardiol 1978; 1:112.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag, Berlin · Heidelberg

About this chapter

Cite this chapter

Sokolow, M., Mcllroy, M.B. (1985). Infektiöse Endokarditis. In: Kardiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69607-7_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69607-7_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69608-4

  • Online ISBN: 978-3-642-69607-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics