Skip to main content
SpringerLink
Log in

Maligne Tumoren des Pankreas und der periampullären Region

  • Chapter
Chirurgische Onkologie

Part of the book series: Die Praxis der Chirurgie ((PRAXCHIR))

Zusammenfassung

Es gibt zahlreiche Beobachtungen, die weltweit einen Anstieg der Häufigkeit des Pankreaskarzinoms verzeichnen. Es ist dabei schwer zu beurteilen, ob tatsächlich eine echte Zunahme vorliegt oder ob diese Zunahme auf die bessere Diagnostik und auf eine Alterszunahme der Bevölkerung zurückzuführen ist. Alle statistischen und epidemiologischen Untersuchungen sind jedoch mit dem Nachteil behaftet, daß die Diagnose Pankreaskarzinom nur in 50–70% histologisch bestätigt ist (Gudjonsson et al. 1978; Levin et al. 1981). Nach Levin et al. (1981) hat das Pankreaskarzinom in den USA in den letzten 40 Jahren bei Männern von 7,7 auf 12,5, bei Frauen von 6,1 auf 8,6 Neuerkrankungen pro 100000 Einwohner und Jahr zugenommen. Je nach Rasse ist ein deutlicher Inzidenzunterschied zu beobachten. Bei weiBen Mannern findet man 11,9, bei schwarzen Mannern 17,5, bei weiBen Frauen 7,7 und bei schwarzen Frauen 11,8 Neu­erkrankungen pro 100000 Einwohner und Jahr.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

Zu 22.1. Karzinome des exokrinen Pankreas und der periampullären Region

  • Ackerman LV, Rosai J (1974) Surgical pathology. Mosby, St. Louis

    Google Scholar 

  • Allen-Mersh TG (1982) Significance of the site of origin of pancreatic exocrine adenocarcinoma. J Clin Path 35:54–546

    Article  Google Scholar 

  • Anacker H, Weiss HD, Kramann B (1975) Das Pankreaskarzinom im endoskopischen retrograden Pancreatico-Cholangiogramm. Fortschr Röntgenstr 122:238–242

    Article  CAS  Google Scholar 

  • Aoki K, Ogawa H (1978) Cancer of the pancreas — international mortality trends. Wld Hlth Stat Rep 31:2–27

    CAS  Google Scholar 

  • Aston SJ, Longmire WP (1973) Pancreatico-duodenal resection. Arch Surg 106:813–817

    PubMed  CAS  Google Scholar 

  • Baylor SM, Berg JW (1973) Cross classification and survival characteristics of 5000 cases of cancer of the pancreas. J Surg Oncol 5:335–357

    Article  PubMed  CAS  Google Scholar 

  • Becker V (1973) Bauchspeicheldrüse, Inselapparat ausgenommen. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  • Berg JW, Connelly RR (1979) Updating the epidemiologic data on pancreatic cancer. Sem Oncol 6:275–284

    CAS  Google Scholar 

  • Björck S, Svensson JO, Macpherson S, Edlund Y (1981) Cancer of the head of the pancreas and choledochoduode-nal junction: A clinical study of 88 Whipple resections. Acta Chir Scand 147:353–359

    PubMed  Google Scholar 

  • Blumgart LH, Kennedy A (1975) Carcinoma of the ampulla of Vater and duodenum. Br J Surg 60:33–40

    Article  Google Scholar 

  • Bockman DE (1981) Cells of origin of pancreatic cancer: Experimental animal tumors related to human pancreas. Cancer 47:1528–1534

    Article  PubMed  CAS  Google Scholar 

  • Bodner E (1981) Chirurgie des Pankreas: Das Pankreaskarzinom. Acta Chir Austr 4:94–100

    Google Scholar 

  • Bowden L, McNeer G, Pack G (1965) Carcinoma of the head of the pancreas. Am J Surg 109:578–582

    Article  PubMed  CAS  Google Scholar 

  • Brooks JR, Culebras JM (1976) Cancer of the pancreas. Am J Surg 131:516–520

    Article  PubMed  CAS  Google Scholar 

  • Bussey HJR (1980) Polyposis syndromes. In: Wright R (ed) Recent advances in gastrointestinal pathology. Saunders, Philadelphia

    Google Scholar 

  • Cancer of the Pancreas Task Force (1981) Staging of cancer of the pancreas. Cancer 47:1631–1637

    Article  Google Scholar 

  • Castellanos J, Manifacio G, Lillehei RC, Shatney CH (1976) Total pancreatectomy for ductal carcinoma of the head of the pancreas: Current status. Am J Surg 131:595–598

    Article  PubMed  CAS  Google Scholar 

  • Cattell RB (1947) Anastomosis of the duct of Wirsung: its use in palliative operations for cancer of the head of the pancreas. Surg Clin North Am 27:636–643

    PubMed  CAS  Google Scholar 

  • Child III CG, Hinerman DL, Kauffman GL Jr (1978) Pancreaticoduodenectomy. Surg Gynecol Obstet 147:529–533

    PubMed  Google Scholar 

  • Classen M, Koch H, Wurbs D, Demling L (1974) Diagnostic and therapeutic aspects of ERCP. In: IIIrd Congr Intern Endosc Gastroint, Mexico

    Google Scholar 

  • Cohen JR, Kuchta N, Geller N, Shires T, Dineen P (1982) Pancreaticoduodenectomy: A 40 year experience. Ann Surg 195:608–617

    Article  PubMed  CAS  Google Scholar 

  • Cohn K Jr (1979) Introduction: Pancreatic cancer. Semin Oncol 6:273–274

    Google Scholar 

  • Cohn I Jr, Hastings PR (eds) (1981) Pancreatic cancer. UICC Technical Report Series, vol 57. UICC, Geneva

    Google Scholar 

  • Collins JJ Jr, Craighead JE, Brooks JR (1966) Rationale for total pancreatectomy for carcinoma of the pancreatic head. N Engl J Med 274:599–602

    Article  PubMed  Google Scholar 

  • Cooperman AM, Herter FP, Marboe CA, Helmreich ZU, Perzin KH (1981) Pancreatoduodenal resection and total pancreatectomy. An institutional review. Surgery 90:707–712

    CAS  Google Scholar 

  • Coutsoftides T, MacDonald J, Shibata HR (1977) Carcinoma of the pancreas and periampullary region: A 41 year experience. Ann Surg 186:730–733

    Article  PubMed  CAS  Google Scholar 

  • Crile G (1970) The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreatic carcinoma. Surg Gynecol Obstet 130:1049–1053

    PubMed  Google Scholar 

  • Cubilla AL, Fitzgerald PJ (1976) Morphological lesions associated with human primary invasive nonendocrine pancreas cancer. Cancer Res 26:2690–2698

    Google Scholar 

  • Cubilla AL, Fitzgerald PJ (1980) Surgical pathology aspects of cancer of the ampulla-head-of-pancreas region. In: Fitzgerald PJ, Morrison AB (eds) The pancreas. Williams & Wilkins, Baltimore

    Google Scholar 

  • Cubilla AL, Fitzgerald PJ, Fortner JG (1978 a) Pancreas cancer — duct cell adenocarcinoma: survival in relation to site, size, stage and type of therapy. J Surg Oncol 10:465–482

    Article  PubMed  CAS  Google Scholar 

  • Cubilla AL, Fortner J, Fitzgerald PJ (1978 b) Lymph node involvement in carcinoma of the head of the pancreas area. Cancer 41:880–887

    Article  PubMed  CAS  Google Scholar 

  • Diamond D, Fisher B (1975) Pancreatic cancer. Surg Clin North Am 55:363–376

    PubMed  CAS  Google Scholar 

  • DiMagno EP, Malagelada JR, Taylor WF, Go VLW (1977) A prospective comparison of current diagnostic tests for pancreatic cancer. N Engl J Med 297:737–742

    Article  PubMed  CAS  Google Scholar 

  • Edis AJ, Kiernan PD, Taylor WF (1980) Attempted curative resection of ductal carcinoma of the pancreas. Review of Mayo Clinic experience, 1951–1975. Mayo Clin Proc 55:531–536

    PubMed  CAS  Google Scholar 

  • Feduska NJ, Dent TL, Lindenauer SM (1971) Results of palliative operations for carcinoma of the pancreas. Arch Surg 103:330–334

    PubMed  CAS  Google Scholar 

  • Feinberg SB, Schreiber DR, Goodale R (1977) Comparison of ultrasound pancreatic scanning and endoscopic retrograde cholangiopancreaticograms; A retrospective study. J Clin Ultrasound 5:96–100

    Article  PubMed  CAS  Google Scholar 

  • Fish JC, Cleveland BR (1964) Pancreaticoduodenectomy for periampullary carcinoma. Ann Surg 159:469–476

    Article  PubMed  CAS  Google Scholar 

  • Forrest JF, Longmire WP Jr (1979) Carcinoma of the pancreas and periampullary region. Ann Surg 189:129–138

    Article  PubMed  CAS  Google Scholar 

  • Fortner JG (1973) Regional resection of cancer of the pancreas: A new surgical approach. Surgery 73:307–320

    PubMed  CAS  Google Scholar 

  • Fortner JG (1981) Surgical principles for pancreatic cancer: Regional total and subtotal pancreatectomy. Cancer 47:1712–1718

    Article  PubMed  CAS  Google Scholar 

  • Fortner JG (1984) Regional pancreatectomy for cancer of the pancreas, ampulla, and other related sites. Tumor staging and results. Ann Surg 199:418–425

    Article  PubMed  CAS  Google Scholar 

  • Fraumeni JF Jr (1975) Cancer of the pancreas and biliary tract: Epidemiological considerations. Cancer Res 35:3437–3446

    PubMed  Google Scholar 

  • Gall FP (1980) Pankreaschirurgie. Entwicklung und Ergebnisse. Fortschr Med 98:1644–1651

    PubMed  CAS  Google Scholar 

  • Gall FP (1986) Chirurgie des duktalen Karzinoms. In: Gall FP, Groitl H (Hrsg) Fortschritte in der Pankreaschirurgie. Zuckschwerdt, München Bern Wien

    Google Scholar 

  • Gall FP, Zirngibl H (1984) Chirurgische Therapie der Pan-kreastumoren. In: Gebhardt Ch (Hrsg) Chirurgie des exo-krinen Pankreas. Thieme, Stuttgart New York

    Google Scholar 

  • Gall FP, Hermanek P, Gebhardt CH, Meier H (1981) Erweiterte Resektion der Pankreas- und periampullären Karzinome: Regionale, totale und partielle Duodenopan-kreatektomie. Leber Magen Darm 11:179–184

    PubMed  CAS  Google Scholar 

  • Gambill EE (1970) Pancreatic and ampullary carcinoma: diagnosis and prognosis in relationship to symptoms, physical findings and relapse of time as observed in 255 patients. South Med J 63:1119–1124

    Article  PubMed  CAS  Google Scholar 

  • Gastrointestinal Tumor Study Group (1979) A multi-institutional comparative trial of radiation therapy alone and in combination with 5-fluorouracil for locally unresectable pancreatic carcinoma. Ann Surg 189:205–208

    Google Scholar 

  • Gebhardt Ch (1984) Chirurgische Therapie der chronischen Pankreatitis. In: Gebhardt Ch (Hrsg) Chirurgie des exo-krinen Pankreas. Thieme, Stuttgart New York

    Google Scholar 

  • George P, Brown C, Gilchrist J (1975) Operative biopsy of the pancreas. Br J Surg 62:280–283

    Article  PubMed  CAS  Google Scholar 

  • Gibson JB, Sobin LH (1978) Histological typing of tumours of the liver, biliary tract and pancreas. International Histological Classifikation of Tumours, No 20. WHO, Geneva

    Google Scholar 

  • Gudjonsson B, Spiro HM (1978) Biopsy techniques in the diagnosis of pancreatic cancer. Gastroenterology 75:726–728

    PubMed  CAS  Google Scholar 

  • Gudjonsson B, Livstone EM, Spiro HM (1978) Cancer of the pancreas. Diagnostic accuracy and survival statistics. Cancer 42:2494–2506

    Article  PubMed  CAS  Google Scholar 

  • Gunderson LL, Shipley WU, Suit HD et al. (1982) Intraoperative irradiation: A pilot study combining external beam photons with “boost” dose intraoperative electrons. Cancer 49:2259–2266

    Article  PubMed  CAS  Google Scholar 

  • Gundry SR, Strodel WE, Knol JA, Eckhauser FE (1983) Efficacy of preoperative percutaneous biliary decompression in patients with obstructive jaundice. Gastroenterology 84. 1177 A

    Google Scholar 

  • Hagenmüller F, Classen M (1982) Therapeutic endoscopie and percutaneous procedures. In: Popper H, Schaffner F (eds) Progress in liver disease, vol 8. Grune & Stratton, New York

    Google Scholar 

  • Hagenmüller F, Soehendra N (1983) Nonsurgical biliary drainage. In: Classen M, Schreiber HW (eds) Biliary tract disorders. Clinics in Gastroenterology, vol 12. Saunders, Philadelphia London

    Google Scholar 

  • Hatfield ARW, Tobias R, Girdwood AH et al. (1982) Is preoperative biliary drainage necessary in obstructive jaundice surgery? Gut 23: A 449

    Google Scholar 

  • Heerden JA van, ReMine MH, Weiland LH, Mcllrath DC, Ilstrup DM (1981) Total pancreatectomy for ductal adenocarcinoma of the pancreas. Mayo Clinic experience. Am J Surg 142:308–311

    Article  PubMed  Google Scholar 

  • Hermanek P (1983) Intraoperative Diagnostik des Pankreaskarzioms. Langenbecks Arch Chir 359:289–299

    Article  PubMed  CAS  Google Scholar 

  • Hermanek P (1984) Pathologie der Pankreastumoren. In: Gebhardt Ch (Hrsg) Chirurgie des exokrinen Pankreas. Thieme, Stuttgart New York

    Google Scholar 

  • Hermanek P (1986 a) Intraoperative histologische Diagnostik. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzi-nom. Frühdiagnostisches und therapeutisches Dilemma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Hermanek P (1986 b) Pathologie des Pankreaskarzinoms. In: Gall FP, Groitl H (Hrsg) Fortschritte in der Pankreas-chirurgie. Zuckschwerdt, München Bern Wien

    Google Scholar 

  • Hermanek P, Giedl J (1986) Lymphogene Metastasierung des Pankreas- und periampullären Karzinoms. Häufigkeit, Topographie. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Frühdiagnostisches und therapeutisches Dilemma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Hermanek P, Wörner U (1979) Pathologie des Pankreaskarzinoms und des periampullären Karzinoms. In: Chirurgie der Bauchspeicheldrüse Bericht über ein Symposium in Erlangen, Bd I. Braun-Dexon, Melsungen

    Google Scholar 

  • Hermann RE (1979) Carcinoma of the pancreas and periampullary region. In: Egdahl RH (ed) Manual of surgery of the gallbladder, bile ducts, and exocrine pancreas. Springer, Berlin Heidelberg New York

    Chapter  Google Scholar 

  • Hermreck A, Thomas C, Friesen S (1974) Importance of pathologic staging in the surgical management of adenocarcinoma of the exocrine pancreas. Am J Surg 127:653–657

    Article  PubMed  CAS  Google Scholar 

  • Herskovic A, Heaston D, Engler MJ, Fishburn RI, Jones RS, Noell KT (1981) Irradiation of biliary carcinoma. Radiology 139:219–222

    PubMed  CAS  Google Scholar 

  • Herter FP, Cooperman AM, Ahlborn TN, Antinori C (1982) Surgical experience with pancreatic and periampullary cancer. Ann Surg 195:274–281

    Article  PubMed  CAS  Google Scholar 

  • Hertzberg J (1974) Pancreatico-duodenal resection and bypass operation in patients with carcinoma of the head of the pancreas, ampulla, and distal end of the common duct. Acta Chir Scand 140:523–527

    PubMed  CAS  Google Scholar 

  • Hicks RE, Brooks JR (1971) Total pancreatectomy for ductal carcinoma. Surg Gynecol Obstet 133:16–20

    PubMed  CAS  Google Scholar 

  • Hines LH, Burns RP (1976) 10 years experience treating pancreatic and periampullary cancer. Am Surg 42:441–447

    PubMed  CAS  Google Scholar 

  • Hoitsma HFW, Meijer S, Den Otter G (1978) Curative and palliative surgical treatment of pancreaticoduodenal adenocarcinoma. Arch Chir Neerl 30:151–161

    PubMed  CAS  Google Scholar 

  • Hollender LF (1978) Möglichkeiten und Grenzen der Pan-kreaschirurgie. Acta Chir Austr 1:84–88

    Article  Google Scholar 

  • Hollender LF, Marrie A (1981) Pancreascarcinom und pe-riampulläres Carcinom. In: Allgöwer M, Harder F, Hollender LF, Peiper HJ, Siewert JR (Hrsg) Chirurgische Gastroenterologie, Bd II. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Hollender LF, Meyer Ch (1978) Operative Behandlung des Pankreaskarzinoms. Zbl Chir 103:1256–1263

    PubMed  CAS  Google Scholar 

  • Ihse J, Lilja P, Arnesjö B, Bengmark S (1977) Total pancreatectomy for cancer. Ann Surg 186:675–680

    Article  PubMed  CAS  Google Scholar 

  • Isaacson R, Weiland LH, Mcllrath DC (1974) Biopsy of the pancreas. Arch Surg 109:227–230

    PubMed  CAS  Google Scholar 

  • Jain JM, Brief DK, Nozick J (1979) Carcinoma of the pancreas: Fifteen years’ experience. Am Surg 45:15–20

    PubMed  CAS  Google Scholar 

  • Kim WS, Barth KH, Zinner M (1982) Seeding of pancreatic carcinoma along the transhepatic catheter tract. Radiology 143:427–428

    PubMed  CAS  Google Scholar 

  • Klapdor R, Lehmann U, Bahlo M, Greten H, Ackeren H von, Dallek U, Kraas E (1983) Validity of CA 19–9 Ria for differential diagnosis of exokrine pancreatic carcinoma. 2nd Europ. Conference on Clinical Oncology, Amsterdam 2–5 November 1983, Abstracts. Koningin Wilhelmina Fonds, Amsterdam 1983

    Google Scholar 

  • Klöppel G, Sosnowski J, Eichfuss H-P, Rückert K, Klapdor R (1979) Aktuelle Aspekte des Pankreaskarzinoms. Dtsch Med Wochenschr 104:1801–1805

    Article  PubMed  Google Scholar 

  • Klöppel G, Bommer G, Rückert K, Seifert G (1980) Intraductal proliferation in the pancreas and its relationship to human and experimental carcinogenesis. Virchows Arch [Pathol Anat] 387:221–233

    Article  Google Scholar 

  • Klöppel G, Lingenthal G, Klapdor R, Kern HF, Rückert K, Bülow M von (1984) Morphologische Kriterien zum Wachstumsverhalten des Pankreaskarzinoms. Dtsch Med Wochenschr 109:702–708

    Article  PubMed  Google Scholar 

  • Knight RW, Scarborough JP, Goss JC (1978) Adenocarcinoma of the pancreas. A ten-year experience. Arch Surg 113:1401–1404

    PubMed  CAS  Google Scholar 

  • Kozuka S, Sassa R, Taki T et al. (1979) Relation of pancreatic duct hyperplasia to carcinoma. Cancer 43:1418–1428

    Article  PubMed  CAS  Google Scholar 

  • Kozuka S, Tsubone M, Yamaguchi A, Hachisuka K (1981) Adenomatous residue in cancerous papilla of Vater. Gut 22:1031–1034

    Article  PubMed  CAS  Google Scholar 

  • Kümmerle F, Kirschner P, Mangold G (1976) Zur Klinik und Chirurgie des Pankreaskarzinoms. Dtsch Med Wo-chenschr 101:729–734

    Article  Google Scholar 

  • Kümmerle F, Trede M, Schwemmle K, Hollender LF (1984) Pankreaskopfcarcinom: Ist die totale Pankreatektomie noch das Verfahren der Wahl? Langenbecks Arch Chir 362:71–74

    Article  PubMed  Google Scholar 

  • Levin B, ReMine WH, Hermann RE, Schein PS, Cohn I (1978) Panel: Cancer of pancreas. Am J Surg 135:185–191

    Article  PubMed  CAS  Google Scholar 

  • Levin DL, Connelly RR, Devesa SS (1981) Demographic characteristics of cancer of the pancreas. Mortality, incidence and survival. Cancer 47:1456–1468

    Article  PubMed  CAS  Google Scholar 

  • Liang V, Go W, Taylor WF, DiMagno EP (1981) Efforts at early diagnosis of pancreatic cancer. Cancer 47:1698–1703

    Article  Google Scholar 

  • Longmire WP Jr, Traverso LW (1981) The Whipple procedure and other standard operative approaches to pancreatic cancer. Cancer 47:1706–1711

    Article  PubMed  Google Scholar 

  • Longnecker DS, Roebuck BD, Yager JD Jr, Lilja HS, Siegmund B (1981) Pancreatic carcinoma in azaserinetreated rates: Induction, classification and dietary modulation of incidence. Cancer 47:1562–1572

    Article  PubMed  CAS  Google Scholar 

  • Lutz HTh, Ehler R, Heyder N, Reichel L (1980) Differentialdiagnostik der Pankreaserkrankungen mit Ultraschall. Ultraschall 1:12–25

    Article  Google Scholar 

  • Lux G, Lutz H (1984) Diagnostik von Pankreastumoren. In: Gebhardt Ch (Hrsg) Chirurgie des exokrinen Pankreas. Thieme, Stuttgart New York

    Google Scholar 

  • Lux G, Schaffner O, Koch H, Rösch W, Stolte M (1977) Duodenoskopische Diagnose des Papillen- und Pankreas-karzinoms-Erfahrungen bei 100 Fällen. In: Lindner H (Hrsg) Fortschritte der gastroenterologischen Endoskopie, Bd 8. Witzstrock, Baden-Baden, S 159–163

    Google Scholar 

  • Macdonald JS, Gunderson LL, Cohn I Jr (1982) Cancer of the pancreas. In: Vita VT Jr, Hellmann S, Rosenberg StA (eds) Cancer, principles and practice of oncology. Lippincott, Philadelphia Toronto

    Google Scholar 

  • Mackie LR, Cooper MJ, Lewis MH, Moossa AR (1979) Non-operative differentiation between pancreatic cancer and chronic pancreatitis. Am Surg 189:480–487

    CAS  Google Scholar 

  • Malagelada J-R (1979) Pancreatic cancer. An overview of epidemiology, clinical presentation and diagnosis. Mayo Clin Proc 54:459–467

    PubMed  CAS  Google Scholar 

  • Matsui Y, Aoki Y, Ishikawa O, Iwanaga T, Wada A, Tateishi R, Kosaki G (1979) Ductal carcinoma of the pancreas. Rationales for total pancreatectomy. Arch Surg 114:722–726

    PubMed  CAS  Google Scholar 

  • Moertel CG (1982) Exocrine pancreas. In: Holland JF, Frei III E (eds) Cancer medicine. 2nd edn. Lea & Febiger, Philadelphia

    Google Scholar 

  • Moertel CG, Lokich JJ, Childs DS, Schein PS, Lavin PT (1976) An evaluation of high dose radiation and combined radiation and 5-fluorouracil (5-FU) therapy for locally unresectable pancreatic carcinoma. Proc Am Soc Clin Oncol 17:244

    Google Scholar 

  • Mongé JJ, Judd ES, Gage RP (1964a) Radical pancreatoduodenectomy: a 22 year-experience with the complications, mortality rate and survival rate. Ann Surg 160:711–722

    Article  PubMed  Google Scholar 

  • Mongé JJ, Dockerty MB, Wollaeger EE, Waugh JM, Priestley JT (1964 b) Clinicopathologic observations on radical pancreatoduodenal resection for periampullary carcinoma. Surg Gynecol Obstet 118:275–283

    PubMed  Google Scholar 

  • Moolgavkar SH, Stevens RG (1981) Smoking and cancers of bladder and pancreas: Risks and temporal trends. J Nat Cancer Inst 67:15–23

    PubMed  CAS  Google Scholar 

  • Moossa AR (1982) Pancreatic cancer. Approach to diagnosis, selection for surgery and choice of operation. Cancer 50:2689–2698

    PubMed  CAS  Google Scholar 

  • Moossa AR, Dawson PJ (1981) The diagnosis of pancreatic cancer. Pathobiol Annu 11:299–335

    PubMed  CAS  Google Scholar 

  • Moossa AR, Levin B (1981) The diagnosis of “early” pancreatic cancer. The University of Chicago experience. Cancer 47:1688–1697

    Article  PubMed  CAS  Google Scholar 

  • Moossa AR, Lewis MH, Mackie CR (1979) Surgical treatment of pancreatic cancer. Mayo Clin Proc 54:468–474

    PubMed  CAS  Google Scholar 

  • Nagakawa T, Kurachi M, Konishi K, Miyazaki I (1982) Translateral retroperitoneal approach in radical surgery for pancreatic carcinoma. Jpn J Surg 12:229–233

    Article  PubMed  CAS  Google Scholar 

  • Nakase A, Matsumoto Y, Uchida K, Honjo I (1977) Surgical treatment of cancer of the pancreas and the periampullary region. Ann Surg 185:52–57

    Article  PubMed  CAS  Google Scholar 

  • Oi I (1973) Duodenoscopy in 14 cases of papillary cancer. In: Demling L, Classen M (eds) Endoscopy of the small intestine with retrograde pancreatocholangiography. Thieme, Stuttgart

    Google Scholar 

  • Papachristou DN, Fortner JG (1981) Pancreatic fistula complicating pancreatectomy for malignant disease. Br J Surg 68:238–240

    Article  PubMed  CAS  Google Scholar 

  • Piorkowski RJ, Blievernicht SW, Lawrence W Jr, Madar-laga J, Horsley JS, Neifeld JP, Terz JJ (1982) Pancreatic and periampullary carcinoma. Experience with 200 patients over a 12 year period. Am J Surg 143:189–193

    Article  PubMed  CAS  Google Scholar 

  • Pliam MB, ReMine WH (1975) Further evaluation of total pancreatectomy. Arch Surg 110:506–511

    PubMed  CAS  Google Scholar 

  • Pollock D, Taylor KJW (1981) Ultrasound scanning in patients with clinical suspicion of pancreatic cancer. Cancer 47:1662–1665

    Article  PubMed  CAS  Google Scholar 

  • Porter MR (1958) Carcinoma of the pancreaticoduodenal area. Operability and choice of procedure. Ann Surg 148:711–724

    Article  PubMed  CAS  Google Scholar 

  • Reddy JK, Scarpelli DG, Rao MS (1979) Experimental pancreatic carcinogenesis. In: Thatcher N (ed) Digestive cancer. Advances in medical oncology research and education, No 9. Pergamon, New York

    Google Scholar 

  • Reed K, Vose PC, Jarstfer BS (1979) Pancreatic cancer: 30 year review (1947–1977). Am J Surg 138:929–933

    Article  PubMed  CAS  Google Scholar 

  • ReMine WH, Priestley JT, Judd ES, King JN (1970) Total pancreatectomy. Ann Surg 172:595–604

    Article  PubMed  CAS  Google Scholar 

  • Rettenmeier G (1976) Leistungsfähigkeit der Sonographie bei Erkrankungen der Bauchspeicheldrüse. In: Bartelhei-mer H, Classen M, Ossenberg FW (Hrsg) Die Untersuchung der Bauchspeicheldrüse. Thieme, Stuttgart

    Google Scholar 

  • Riemann JF, Demling L (Hrsg) (1985) Endotherapie von Gallenwegserkrankungen. Thieme, Stuttgart New York

    Google Scholar 

  • Rosai J (1981) Ackerman’s surgical pathology, 6th edn. Mosby, St. Louis

    Google Scholar 

  • Rosch J, Keller FS (1981) Pancreatic arteriography, transhepatic pancreatic venography and pancreatic venous sampling in diagnosis of pancreatic cancer. Cancer 47:1679–1684

    Article  PubMed  CAS  Google Scholar 

  • Rosenberger J, Mödder U, Pichlmaier H, Friedmann G (1979) Die Computer-Tomographie des Pankreas. Münch Med Wochenschr 121:1037–1040

    CAS  Google Scholar 

  • Ross H, Jonas RA (1980) The results of surgery for carcinoma of the pancreas. Aust NZJ Surg 50:454–458

    Article  CAS  Google Scholar 

  • Rossmann P (1959) Lungenmetastasen des Pankreaskrebses mit klinischem Bild des Alveolarkrebses. Zentralbl Allg Pathol 99:301

    Google Scholar 

  • Rückert K, Kümmerle F (1979) Das Papillenkarzinom. Chirurg 50:308–312

    PubMed  Google Scholar 

  • Rückert K, Kümmerle F (1986) Ergebnisse der totalen Duodenopankreatektomie als Regeloperation beim Pankreaskarzinom. In: Beger HG, Bittner R (Hrsg) Das Pankreaskarzinom. Frühdiagnostisches und therapeutisches Dilemma. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Sarles H, Sahel J (1976) Die chronische Pankreatitis. In: Schwiegk H (Hrsg) Handbuch der inneren Medizin, Bd III/6: Pankreas. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Sarr MG, Cameron JL (1982) Surgical management of unresectable carcinoma of the pancreas. Surgery 91:123–133

    PubMed  CAS  Google Scholar 

  • Sato T, Saitoh Y, Noto N, Matsuno S (1977) Follow-up studies of radical resection for pancreaticoduodenal cancer. Ann Surg 186:581–588

    Article  PubMed  CAS  Google Scholar 

  • Sato T, Saitoh Y, Noto N, Matsuno S (1978) Factors influencing the late results of operation for carcinoma of the pancreas. Am J Surg 136:581–586

    Article  Google Scholar 

  • Scheithauer W (1984) Chemotherapie des metastasier-ten Pankreaskarzinoms. Tumor-Diagnostik Therapie 5:44–48

    Google Scholar 

  • Schmid P (1979) Palliative oder radikale Chirurgie beim pankreatikoduodenalen Karzinom. Helv Chir Acta 46:819–821

    Google Scholar 

  • Seifert E (1982) Diagnostik und endoskopische Therapie der Papillentumoren. Schweiz Rdsch Med 71:394–396

    CAS  Google Scholar 

  • Seifert G, Klöppel G (1979) Diagnostic value of pancreatic biopsy. Path Res Pract 164:357–384

    Article  PubMed  CAS  Google Scholar 

  • Sellner F, Jelinek R (1979) Behandlungsergebnisse nach partieller Duodenopankreatektomie. Wien Med Wochenschr 23:682–685

    Google Scholar 

  • Shapiro TM (1975) Adenocarcinoma of the pancreas: a statistical analysis of biliary bypass vs. Whipple resection in good risk patients. Ann Surg 182:715–721

    Article  PubMed  CAS  Google Scholar 

  • Smith R (1973) Progress in the surgical treatment of pancreatic disease. Am J Surg 125:143–153

    Article  PubMed  CAS  Google Scholar 

  • Smith FP, Macdonald JS, Schein PS, Ornitz RD (1980) Cutaneous seeding of pancreatic cancer by skinny-needly aspiration biopsy. Arch Intern Med 140:855

    Article  PubMed  CAS  Google Scholar 

  • Stadelmann O, Safrany L, Löffler A et al. (1974) Endoscopic retrograde cholangiopancreaticography in the diagnosis of pancreatic cancer. Endoscopy 6:84–93

    Article  Google Scholar 

  • Statistisches Bundesamt Wiesbaden (1983) Todesursachen 1981. Gesundheitswesen, Fachserie 12, Reihe 4. Kohlhammer, Stuttgart Mainz

    Google Scholar 

  • Strohm W-D, Kurtz W, Hagenmüller F, Classen M (1984) Diagnostic efficacy of endoscopic ultrasound tomography in pancreatic cancer and cholestasis. Scand J Gastroenterol [Suppl 102] 19:18–23

    Google Scholar 

  • Trede M (1982) Pankreaskarzinom. In: Encke A, Jungbluth KH, Röher HD, Trede M (Hrsg) Aktuelle chirurgische Onkologie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Trede M, Kersting KM, Hottmeister A (1977) Das Pankreaskarzinom. Münch Med Wochenschr 119:617–622

    CAS  Google Scholar 

  • Tryka AF, Brooks JR (1979) Histopathology in the evaluation of total pancreatectomy for ductal carcinoma. Ann Surg 190:373–379

    Article  PubMed  CAS  Google Scholar 

  • Volkholz H, Stolte M, Klöppel G (1981) Das villöse Adenom der Papilla Vateri — Vorläufer des Pankreaskarzinoms? Verh Dtsch Ges Path 65:375

    Google Scholar 

  • Walsh DB, Eckhauser FE, Cronenwett JL, Turcotte JG, Lindenauer SM (1982) Adenocarcinoma of the ampulla of Vater. Diagnosis and treatment. Ann Surg 195:152–157

    Article  PubMed  CAS  Google Scholar 

  • Warren KW, Jefferson MF (1973) Carcinoma of the endocrine pancreas. In: Carcy LC (ed) The pancreas. Mosby, St. Louis

    Google Scholar 

  • Warren KW, Cattell RB, Blackburn JP, Nora PF (1962) A long-term appraisal of pancreaticoduodenal resection for periampullary carcinoma. Ann Surg 155:653–662

    Article  PubMed  CAS  Google Scholar 

  • Warren KW, Choe DS, Plaza J, Relihan M (1975) Results of radical resection for periampullary cancer. Ann Surg 181:534–540

    Article  PubMed  CAS  Google Scholar 

  • Watanabe M, Nishimura Y (1977) Recent advance in the diagnostic and therapy of cancer of the pancreas and the biliary tract, with special reference to the significance of combined use of endoscopic retrograde cholangiopancreatography and selective celiac arteriography. Gastroenterol Jpn 12:88

    Google Scholar 

  • Weill FS (1982) Ultraschalldiagnostik in der Gastroenterologie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Whipple AO, Parsons WB, Mullins CR (1935) Treatment of carcinoma of the ampulla of Vater. Ann Surg 102:763–776

    Article  PubMed  CAS  Google Scholar 

  • Wiechel K-L (1985) Perkutane transhepatische Drainage bei malignem Verschlußikterus. In: Riemann JF, Demling L (Hrsg) Endotherapie von Gallenwegserkrankungen. Thieme, Stuttgart New York

    Google Scholar 

  • Williams JA, Cubilla A, Maclean BJ, Fortner JG (1979) Twenty-two year experience with periampullary carcinoma at Memorial Sloan-Kettering Cancer Center. Am J Surg 138:662–665

    Article  PubMed  CAS  Google Scholar 

  • Wise L, Pizzinboro C, Dehner LP (1976) Periampullary cancer — a clinicopathological study of 62 patients. Am J Surg 131:141–148

    Article  PubMed  CAS  Google Scholar 

  • Wongsuwanporn T, Basse E (1983) Palliative surgical treatment of sixty-eight patients with carcinoma of the head of the pancreas. Surg Gynecol Obstet 156:73–75

    PubMed  CAS  Google Scholar 

  • Wynder EL (1975) An epidemiological evaluation of the causes of cancer of the pancreas. Cancer Res 35:2228–2233

    PubMed  CAS  Google Scholar 

  • Yasuda K, Tanaka Y, Fujimoto S, Nakajima M, Kawai K (1984) Use of endoscopic ultrasonography in small pancreatic cancer. Scand J Gastroenterol [Suppl 102] 19:9–17

    Google Scholar 

Zu 22.2 Maligne Tumoren des endokrinen Pankreas

  • Binnick AN, Spencer SK, Dennison WL Jr, Horton ES (1977) Glucagonoma syndrome. Report of two cases and literature review. Arch Dermatol 113:749–754

    Article  PubMed  CAS  Google Scholar 

  • Brennan MF, MacDonald JS (1982) Cancer of the endocrine system: The endocrine pancreas. In: Vita VT de Jr, Hellmann S, Rosenberg SA (eds) Cancer, principles and practice of oncology. Lippincott, Philadelphia Toronto

    Google Scholar 

  • Broder LE, Carter SK (1973 a) Pancreatic islet cell carcinoma. I. Clinical features of 52 patients. Ann Intern Med 79:101–107

    PubMed  CAS  Google Scholar 

  • Broder LE, Carter SK (1973 b) Pancreatic islet cell carcinoma. II. Results of therapy with streptozotocin in 52 patients. Ann Intern Med 79:108–118

    PubMed  CAS  Google Scholar 

  • Cubilla A, Hajdu SI (1975) Islet cell carcinoma of the pancreas. Arch Pathol 99:204–207

    PubMed  CAS  Google Scholar 

  • Edis AJ, McIlrath DC, Heerden JA van, Fulton RE, Sheedy PF, John Service F, Dale AJD (1976) Insulinoma — Current diagnosis and surgical management. Curr Probl Surg 13:1–45

    Article  PubMed  CAS  Google Scholar 

  • Feyrter F (1938) Über diffuse endokrine epitheliale Organe. Barth, Leipzig

    Google Scholar 

  • Fox PS, Hofmann JW, DeCosse JJ, Wilson SD (1974a) The influence of total gastrectomy on survival in malignant Zollinger-Ellison syndrome. Ann Surg 180:558–565

    Article  PubMed  CAS  Google Scholar 

  • Fox PS, Hofmann JW, Wilson SD, DeCosse JJ (1974 b) Surgical management of the Zollinger-Ellison syndrome. Surg Clin North Am 54:395–407

    PubMed  CAS  Google Scholar 

  • Gray RK, Rosch J, Grollmann JH (1970) Arteriography in the diagnosis of islet cell tumors. Radiology 97:39–44

    PubMed  CAS  Google Scholar 

  • Günther R, Kümmerle F, Beyer J, Klose K, Kuhn FP, Rük-kert K (1981) Lokalisationsdiagnostik von Inselzelltumo-ren durch Sonographie, Computertomographie, Arteriographie und selective transhepatische Blutentnahme. Fortschr Röntgenstr 135:657–662

    Article  Google Scholar 

  • Heitz PU, Steiner H (1981) Pluriglanduläre endokrine Regulationsstörungen. In: Doerr W, Seifert G (Hrsg) Spezielle pathologische Anatomie, Bd 14/II. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Heitz PU, Kasper M, Polak JM, Klöppel G (1982) Pancreatic endocrine tumors: immunocytochemical analysis of 125 tumors. Human Pathology 13:263–271

    Article  PubMed  CAS  Google Scholar 

  • Heitz PU, Kasper M, Klöppel G, Polak JM, Vaitukaitis JL (1983) Glycoprotein-hormone alpha-chain production by pancreatic endocrine tumors: a specific marker for malignancy. Cancer 51:277–282

    Article  PubMed  CAS  Google Scholar 

  • Higgins G A, Recant L, Fischman AB (1979) The glucago-noma syndrome: Surgically curable diabetes. Am J Surg 137:142–148

    Article  PubMed  CAS  Google Scholar 

  • Ingemansson S, Kuhl C, Larsson LI, Lunderquist A, Nobin A (1977) Islet cell hyperplasia localized by pancreatic vein catheterization and insulin radioimmunoassay. Am J Surg 133:643–645

    Article  PubMed  CAS  Google Scholar 

  • Klöppel G (1981) Endokrines Pankreas und Diabetes mellitus. In: Doerr W, Seifert G (Hrsg) Pathologie der endokrinen Organe. Spezielle pathologische Anatomie, Bd 14/I. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Klöppel G, Seifert G, Heitz PU (1979) Endokrine Pankreas-tumoren. Morphologie und Syndrome. Dtsch Med Wo-chenschr 104:1571–1577

    Article  Google Scholar 

  • Larsson L-I, Grimelius L, Hakanson R, Rehfeld JF, Stadil F, Holst J, Angervall L, Sundler F (1975) Mixed endocrine pancreatic tumors producing several peptide hormones. Am J Pathol 79:271–280

    PubMed  CAS  Google Scholar 

  • Macdonald JS, Widerlite L, Schein PS (1977) Biology, diagnosis and chemotherapeutic management of pancreatic malignancy. Adv Pharmacol Chemother 14:107

    Article  PubMed  CAS  Google Scholar 

  • Moertel CG, Hanley JA, Johnson LA (1980) Streptozotocin alone compared with streptozotocin plus fluorouracil in the treatment of advanced islet-cell carcinoma. N Engl J Med 303:1189–1194

    Article  PubMed  CAS  Google Scholar 

  • Pearse AGE (1969) The cytochemistry and ultrastructure of polypeptide hormone producing cells of the APUD series, and the embryologic, physiologic and pathologic implications of the concept. J Histochem Cytochem 17:303–313

    Article  PubMed  CAS  Google Scholar 

  • Pistolesi GF, Frasson F, Fugazolla C, Taddei GT, Caresano A (1977) Angiographie diagnosis of endocrine tumors of the pancreas. Radiol Clin 46:401–421

    CAS  Google Scholar 

  • Stefanini P, Carboni M, Patrassi N, Basoli A (1974) Beta-islet cell tumors of the pancreas: results of a study on 1067 cases. Surgery 75:597–609

    PubMed  CAS  Google Scholar 

  • Thompson JC, Reeber DD, Villar HV, Fender HR (1975) Natural history and experience with diagnosis and treatment of the Zollinger-Ellison syndrome. Surg Gynecol Obstet 140:721–739

    PubMed  CAS  Google Scholar 

  • Turner RC, Morris RJ, Lee ECG, Harris EA (1978) Localization of insulinomas. Lancet 1:515–518

    Article  PubMed  Google Scholar 

  • Wermer P (1974) Multiple endocrine adenomatosis; multiple hormoneproducing tumours, a familial syndrome. Clin Gastroenterol 3:671–684

    Google Scholar 

  • Williams ED, Siebenmann RE, Sobin LH (1980) Histological typing of endocrine tumours. International histological classification of tumours, No 23. WHO, Geneva

    Google Scholar 

Download references

Authors
  1. F. P. Gall
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Zirngibl
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Chirurgische Klinik der Universität Erlangen-Nürnberg, Maximiliansplatz, 8520, Erlangen, Deutschland

    Franz Paul Gall (Prof. Dr. med.) (Prof. Dr. med.)

  2. Abteilung für Klinische Pathologie, Chirurgische Universitätsklinik, Maximiliansplatz, 8520, Erlangen, Deutschland

    Paul Hermanek (Prof. Dr. med.) (Prof. Dr. med.)

  3. Chirurgische Abteilung, Städtisches Krankenhaus, Spitalstraße 4, 8550, Forchheim, Deutschland

    Jürgen Tonak (Priv.-Doz. Dr. med.) (Priv.-Doz. Dr. med.)

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Gall, F.P., Zirngibl, H. (1986). Maligne Tumoren des Pankreas und der periampullären Region. In: Gall, F.P., Hermanek, P., Tonak, J. (eds) Chirurgische Onkologie. Die Praxis der Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69600-8_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69600-8_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69601-5

  • Online ISBN: 978-3-642-69600-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation