Abstract
Some patients with anorexia nervosa are somewhat overweight prior to their illness and they give a history of initial dieting to reduce their weight. In a number of cases their food reduction is initially not severe and they have gradual weight loss without any interference with menstruation. After a period of perhaps a few months, they describe a relatively sudden change in their attitude to food; frequently they use the same words to describe this change: “Suddenly the diet took over.” They mean by this that they no longer feel they are in command of their eating habits and they feel as if something inside them is determining more dramatic reduction in food intake and consequently in weight also. From this point on, they frequently have no more menstrual periods.
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References
Benedict FC (1915) A study of prolonged fasting. Carnegie Institution of Washington, Washington
Dally P (1969) Anorexia nervosa. Heinemann, London
Ghosh P, Mills IH, Moore R (1977) The antiketotic effect of opiate receptor blockade by naloxone infusion in human diabetes. J Physiol 271: 51–52 P
Henriksen SJ, Chouvet G, McGinty J, Bloom FE (1982) Opioid peptides in the hippocampus: anatomical and physiological considerations. In: Verebey K (ed) Opioids in mental illness. Ann NY Acad Sci 398: 207–219
Kovacs GL, de Wied D (1981) Endorphin influence on learning and memory. In: Martinez JL, Jensen RA, Messing RB, Rigter H, McGaugh JL (eds) Endogenous peptides and learning and memory processes. Academic Press, New York, pp 231–247
Mills IH (1976) Amitriptyline therapy in anorexia nervosa. Lancet 25: 687
Mills IH (1981) The coping mechanism. In: Edholm OG, Weiner JS (eds) Principles and practice of human physiology. Academic Press, London, pp 425–449
Mills IH, Wilson RJ, Eden MAM, Lines JG (1973) Endocrine and social factors in self-starvation amenorrhoea. In: Robertson RF (ed) Symposium - anorexia nervosa and obesity. Royal College of Physicians of Edinburgh, Edinburgh, pp 31–43 (publication number 42 )
Moore R, Mills IH, Forster A (1981) Naloxone in the treatment of anorexia nervosa: effect on weight gain and lipolysis. J R Soc Med 74: 129–131
Popper KR, Eccles JC (1977) The self and its brain. Springer, Berlin Heidelberg New York
Poulton EC (1970) Environment and human efficiency. Thomas, Springfield
Schneiden H, Cox B (1976) A comparison between amantadine and bromocriptine using the stereotyped behaviour response test ( SBR) in the rat. Eur J Pharmacol 39: 133—141
Yamamoto M, Kawamuki K, Satoh M, Tagaki H (1981) Excitatory action of microelectro- phoretically applied kyotorphin (Tyr-Arg) on unitary activity in the rat cerebral cortex. In: Takagi H, Simon EJ (eds) Advances in endogenous and exogenous opioids. Kodansha, Tokyo, pp 220–222
Yamamoto M, Kawamuki K, Satoh M, Takagi H (1982) Kyotorphin (1-Tyr-l-Arg) inhibits extinction of pole-jumping avoidance response in the rat. Neurosci Lett 31: 175–179
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© 1984 Springer-Verlag Berlin Heidelberg
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Mills, I.H., Medlicott, L. (1984). The Basis of Naloxone Treatment in Anorexia Nervosa and the Metabolic Responses to It. In: Pirke, K.M., Ploog, D. (eds) The Psychobiology of Anorexia Nervosa. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69594-0_15
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DOI: https://doi.org/10.1007/978-3-642-69594-0_15
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