Abstract
Today, muscle relaxants are the most important adjunct in anesthesiology. Their purpose is to maintain muscular relaxation over a long period at a predetermined level of anesthesia appropriate for surgery. Consequently, both the patient’s condition and perioperative requirements have to be considered. In intensive care, numerous therapeutic procedures also have to be taken into account. Broadly, two groups of relaxants with different mechanisms of action are available for clinical use — depolarizing and nondepolarizing substances (Lee and Atkinson 1978, Benzer et al. 1982).
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References
A. Textbooks and Summaries
Benzer H, Frey R, Hügin W, Mayrhofer O (1982) Lehrbuch der Anästhesiologie, Reanimation und Intensivtherapie. Springer, Berlin Heidelberg New York
Brechner VL, Walter RD, Dillon JB (1962) Practical electroencephalography for the anesthesiologist. Thomas, Springfield
Lee JA, Atkinson RS (1978) Synopsis der Anästhesie. Fischer, Stuttgart
B. Papers
Cohen EN, Hood N, Golling R (1968) Use of wholebody autoradiography for determination of uptake and distribution of labelled muscle relaxants in the rat. Anesthesiology 29:987–993
Davis HS, Dillon WH, Collins WF, Randt CT (1958) Effect of anesthetic agents on evoked central nervous system responses: muscle relaxants and volatile agents. Anesthesiology 19:441–449
Feldmann SA (1973) Muscle relaxants. Saunders, London 1–150
Foldes FF (1972) The rationed use of neuromuscular blocking agents: the role of pancuronium. Drugs 4:153–162
Grob D (1967) Neuromuscular blocking drugs. Effect on central nervous system. In: Root WS, Hoffmann FG (eds) Physiological pharmacology. Academic Press, New York p 449–454
Kiersey DK, Bickford RG, Faulconer A Jr (1951) Electroencephalographic patterns produced by thiopental sodium during surgical operations. Description and classification. Br J Anaesth 23:141–152
Mori K, Iwabuchi K, Fujita M (1973) The effect of depolarizing muscle relaxants on the electroencephalogram and the circulation during halothane anaesthesia in man. Br J Anaesth 45:604–610
Smith SM, Brown HO, Toman JEP, Goodman LS (1947) Lack of cerebral effects of d-tu-bocurarine. Anesthesiology 8:1–14
Shea LT, Davidson GM, Davis J (1954) Electroencephalographic studies of curarized patients. Med J Aust 2:656–659
von Wild K (1980) lïerexperimentelle Untersuchungen über die Beeinflussung des EEG durch Muskelrelaxantien am Beispiel von Pancuronium und Succinylbischolin. In: Opitz A, Degen R (ed) Anästhesie bei zerebralen Krampfanfállen und Intensivtherapie des Status epilepticus. Perimed, Erlangen p. 45–55
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© 1984 Springer-Verlag Berlin Heidelberg
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Pichlmayr, I., Lips, U., Künkel, H. (1984). Muscle Relaxants. In: The Electroencephalogram in Anesthesia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69562-9_9
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DOI: https://doi.org/10.1007/978-3-642-69562-9_9
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-69564-3
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