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Glykosaminoglykane in Harnblasenkarzinomen

  • Chapter
Das Harnblasenkarzinom

Zusammenfassung

Proteoglykane bzw. GAG bilden einen Hauptbestandteil der sogenannten Grundsubstanzen des Bindegewebes. Da in fast allen Organen bindegewebige Anteile nachweisbar sind, ist das Vorkommen von Proteoglykanen bzw. GAG weit verbreitet.

Ein vom Minister für Wissenschaft und Forschung des Landes Nordrhein-Westfalen gefördertes Forschungsvorhaben

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Abbreviations

CH:

Chondroitin

CH-4-S:

Chondroitin-4-sulfat

CH-6-S:

Chondroitin-6-sulfat

DS:

Dermatansulfat

GAG:

Glykosaminoglykane

Gal-N:

Galaktosamin

Glc-N:

Glucosamin

HA:

Hyaluronsäure

KS:

Keratansulfat

TG:

Trockengewicht

Literatur

  1. Althausen AF, Prout GR, Daly JJ (1976) Non-invasive papillary carcinoma of the bladder associated with carcinoma in situ. J Urol 116: 575

    PubMed  CAS  Google Scholar 

  2. Baker SR, Blithe DL, Buck CA, Warren L (1980) Glycosaminoglycans and other carbohydrate groups bound to proteins of control and transformed cells. J Biol Chem 255: 8719

    PubMed  CAS  Google Scholar 

  3. Bartfeld H (1969) Distribution of rheumatoid factor activity in non-rheumatoid states. Ann NY Acad Sci 168: 30

    PubMed  CAS  Google Scholar 

  4. Bastable JRG, Richards B, Haworth S, Cooper EH (1979) Acute phase reactant proteins in the clinical management of carcinoma of the bladder. Br J Urol 51: 283

    PubMed  CAS  Google Scholar 

  5. Bichler KH, Ideler V, Harzmann R (1979) Uromucoid excretion in normal individuals and stone formers. Curr Probl Clin Biochem 9: 309

    PubMed  CAS  Google Scholar 

  6. Bichler KH, Korn S (1981) GAG-Ausscheidung bei Patienten mit Urolithiasis. Fortschr Urol Nephrol 17: 203

    Google Scholar 

  7. Bitter T, Muir HM (1962) A modified uronic carbacole reaction. Anal 4: 330

    CAS  Google Scholar 

  8. Block N, Jaksy J, Tessler AN (1974) Carcinoma of urinary tract. Clinical significance of urinary phosphokinase activity in diagnosis. Urology 4: 194

    Google Scholar 

  9. Bloom F (1954) Pathology of the dog and cat. Am Vet Publ Inc Evanston, I II

    Google Scholar 

  10. Blumberg BS, Ogston AG, Lowther DA, Rogers HJ (1958) Physicochemical properties of hyaluronic acid formed by Streptococcus haemolyticus. Biochem 70: 1

    CAS  Google Scholar 

  11. Bodenstab W, Stauffer C, Schmidt JD, Parsons CL (1982) Protective effects of bladder surface glycosaminoglycans against carcinogenic agents. American Urological Association, 77th Annual Meeting

    Google Scholar 

  12. Boenig H (1942) Leitfaden der Entwicklungsgeschichte des Menschen. Thieme, Leipzig, 2. Aufl, S 260

    Google Scholar 

  13. Boyland E, Wallace DM, Williams DC (1955) The activity of the enzyme sulphatase and ß-glucoronidase in the urine, serum and bladder tissue. Br J Cancer 9: 62

    PubMed  CAS  Google Scholar 

  14. Bredin HC, Daly JJ, Prout GR Jr (1975) Lactic dehydrogenase isoenzymes in human bladder cancer. J Urol 113: 199

    Google Scholar 

  15. Bucher 0 (1973) Cytologie, Histologie and mikroskopische Anatomie des Menschen. 8. Aufl, S 468

    Google Scholar 

  16. Callhan HJ, Fritz R, Cooper HS, Grant Mulholland S (1982) Isolation and preliminary characterization of a high molecular weight glycoprotein from rabbit bladder mucosa. American Urological Association, 77th Annual Meeting

    Google Scholar 

  17. Catalona WJ (1981) Practical utility of specific red cell adherence test in bladder cancer. Urology 18: 113

    PubMed  CAS  Google Scholar 

  18. Chiarugi VP, Dietrich CP (1979) Sulfated mucopolysaccharides from normal and virus transformed rodent fibroblasts. J Cell Physiol 99: 201

    PubMed  CAS  Google Scholar 

  19. Chwalla R (1927) Eine bemerkenswerte Anomalie der menschlichen Harnblase. Virchows Arch [Pathol Anat] 263: 632

    Google Scholar 

  20. Cooper PH, Waisman J, Johnston WH, Skinner DG (1973) Severe atypia of transitional epithelium and carcinoma of the urinary bladder. Cancer 31: 1055

    PubMed  CAS  Google Scholar 

  21. Cooper TP, Wheelis RF, Correa RJ, Gibbons RP, Mason JT, Cummings KB (1977) Random mucosal biopsies in the evaluation of patients with carcinoma of the bladder. J Urol 117: 46

    PubMed  CAS  Google Scholar 

  22. Cunnings KB (1980) Carcinoma of the bladder: Predictors. Cancer 45: 1849

    Google Scholar 

  23. Daly JJ (1976) Carcinoma in situ of the urothelium. Urol Clin North Am 3: 87

    PubMed  CAS  Google Scholar 

  24. Dermer GB, Kern WH (1974) Changes in the affinity of phosphotungstic acid and positively charged colloidal particles for the surfaces of malignant human transitional epithelium of the urinary bladder. Cancer Res 34: 2011

    PubMed  CAS  Google Scholar 

  25. Dietrich CP, Sampaio LO, Toledo OMS (1976) Characteristic distribution of sulfated mucopolysaccharides in different tissues and in their respective mitochondria. Biochem Biophys Res Commun 71: 1

    PubMed  CAS  Google Scholar 

  26. Dietrich CP, Sampaio LO, Toledo OMS, Cassaro CMF (1977) Cell recognition and adhesiveness: a possible role for the sulfated mucopolysaccharides. Biochem Biophys Res Commun 75: 329

    PubMed  CAS  Google Scholar 

  27. Dietrich CP, Montes de Oca H (1978) Surface sulfated mucopolysaccharides of primary and permanent mammalian cell lines. Biochem Biophys Res Commun 80: 805

    CAS  Google Scholar 

  28. Dunning WF, Curtis MR, Maun ME (1950) The effect of added dietary tryptophan on the recurrence of 2-acetylamino-fluorene-induced liver and bladder cancer in rats. Cancer Res 10: 454

    PubMed  CAS  Google Scholar 

  29. Endo M, Yamamoto M, Munakata H, Yamamoto R, Namike O, Yosizawa Z (1980) Chemical nature of human urinary glycosaminoglycans. Tohoku J Exp Med 131: 355

    PubMed  CAS  Google Scholar 

  30. Farrow GM, Utz DC, Rife CC, Greene LF (1977) Clinical observations on sixty-nine cases of in situ carcinoma of the urinary bladder. Cancer Res 37: 2794

    PubMed  CAS  Google Scholar 

  31. Fratantoni JC, Hall CW, Neufeld EF (1968) Defect in Hurler and Hunter syndromes. II. Deficiency of specific factors involved in mucopolysaccharide degradation. Proc Natl Acad Sci USA 60: 699

    Google Scholar 

  32. Friman C, Juvani M (1975) Urinary excretion and glycosaminoglycans in malignant diseases of the haemopoietic and lymphatic tissues. Acta Med Scand 198: 115

    PubMed  CAS  Google Scholar 

  33. Gill WB, Jones KW, Ruggiero KJ (1982) Protective effects of heparin and other sulfated glycosaminoglycans on crystal adhesion to injured urothelium. J Urol 127: 152

    PubMed  CAS  Google Scholar 

  34. Gjaldbaek JC, Robertson WG (1980) Does urine from stone-formers contain macromolecules which promote the crystal growth rate of calcium oxalate crystals in vitro? Clin Chim Acta 108: 75

    PubMed  CAS  Google Scholar 

  35. Greiling H, Stuhlsatz HW (1964) Chromatographische Untersuchungen über die Mucopolysaccharidverteilung im hyalinen Knorpel. Hoppe Seylers Z Physiol Chem 336: 149

    PubMed  CAS  Google Scholar 

  36. Greiling H (1974) Glycosaminoglycans. In: Curtius HC, Roth M (eds) Clinical biochemistry, principles and methods, De Gruyter, Berlin 945

    Google Scholar 

  37. Greiling H, Eberhard A (1974) Chondroitin-4-sulfat, Chondroitin-6-sulfat and Dermatansulfat. In: Bergmeyer (Hrsg) Methoden der enzymatischen Analyse. Verlag Chemie, Weinheim, 3. Aufl, Bd I I

    Google Scholar 

  38. Gröbe H (1982) Mucopolysaccharidosen. Dtsch Ärzteblatt 79: 33

    Google Scholar 

  39. Gupta NP, Malaviya AN, Singh SM (1979) Rheumatoid factor; correlation with recurrence in transitional cell carcinoma of the bladder. J Urol 121: 417

    PubMed  CAS  Google Scholar 

  40. Hanno PM, Parson CL, Shrom SH, Fritz R, Mulholland SG (1978) The protective effect of heparin in experimental bladder infection. J Surg Res 25: 324

    PubMed  CAS  Google Scholar 

  41. Harzmann R, Heller W, Bichler KH, Gericke D, Grötsch H, Schmidt K (1979) The value of urinary enzyme diagnosis in urinary bladder carcinoma-experimental and clinical research data. Curr Probl Clin Biochem 9: 113

    PubMed  CAS  Google Scholar 

  42. Hay RJ (1978) Preservation of cell culture stocks in liquid nitrogen. TCA Manual 4: 787

    Google Scholar 

  43. Hay RJ (1980) Pers. Mitteilung

    Google Scholar 

  44. Hennessey PT, Hurst RE, Hemstreet III GP, Cutter G (1981) Urinary glycosaminoglycan excretion as a biochemical marker in patients with bladder carcinoma. Cancer 41: 3868

    CAS  Google Scholar 

  45. Hisazumi H, Naito K, Misakt T, Kosaka S (1974) Urokinase inhibitor in patients with bladder cancer. Urol Res 2: 137

    PubMed  CAS  Google Scholar 

  46. Hopwood JJ, Dorfman A (1978) Glycosaminoglycan synthesis by Wilm’s Tumor. Pediatr Res 12: 52

    PubMed  CAS  Google Scholar 

  47. Hukill PB, Vidone RA (1965) Histochemistry of mucus and other polysaccharides in tumors I. Carcinoma of the bladder. Lab Invest 14: 1624

    Google Scholar 

  48. Huri L, Perttala Y (1965) Observation on nonspecific Waaler-Rose and latex reactions in cancer patients. Ann Med Intern Fenn 54: 181

    Google Scholar 

  49. Irving CC (1977) Biochemically detectable tumor markers in urine of bladder cancer patients. Cancer Res 37: 2872

    PubMed  CAS  Google Scholar 

  50. Ishibe T, Mori K, Usui T, Nihira H, Yasuihi K (1975) Alternations of serum lactic dehydeogenase and its isoenzyme fraction levels following hyperglycemic in patients with bladder carcinoma. Urol Int 30: 437

    PubMed  CAS  Google Scholar 

  51. Jakse G, Hofstädter F (1981) ABH Antigenicity of in situ carcinoma of the urinary bladder during intracavity treatment with doxorubicin hydrochloride. Urol Res 9: 153

    PubMed  CAS  Google Scholar 

  52. Javadpour N (1979) Immunobiology of the genitourinary cancers and their biologic markers. In: Javadpour N (ed) Principles and management of urologic cancer. Williams and Wilkins Comp., Baltimore

    Google Scholar 

  53. Jeanloz RW (1960) The nomenclature of mucopolysaccharides Arthritis Rheum 3: 233

    CAS  Google Scholar 

  54. Johansson B, Ljungqvist A (1974) Localization of immunoglubulins in urinary bladder tumors. Acta Pathol Microbiol Scand [A] 82: 559

    CAS  Google Scholar 

  55. Koss LG, Tiamson EM, Robbins MA (1974) Mapping cancerous and precancerous bladder changes. A study of the urothelium in ten surgically removed bladders. JAMA 227: 281

    Google Scholar 

  56. Kupchella CE, Drake E, Kennedy J, Curran KL, Warick R, Morris HP (1981) Tissue and urinary glycosaminoglycan patterns associated with a fast, an intermediate, and a slow-growing morris hepatoma. Cancer Res 41: 419

    PubMed  CAS  Google Scholar 

  57. Kuwahara M, Tokiwa M, Orikasa S (1982) Bacterial infection and acid mucopolysaccharides in epithelium of rat urinary bladder. Urol Res 10: 93

    PubMed  CAS  Google Scholar 

  58. Lagunoff D, Pritzl P, Scott CR (1967) Urinary N-sulfate glycosaminoglycan excretion in children: normal and abnormal values. Proc Soc Exp Biol Med 126: 34

    Google Scholar 

  59. Levin S, Richter WR (1975) Ultrastructure of cell surface coat (glycocalyx) in rat urinary bladder epithelium. Cell Tissue Res 155: 281

    Google Scholar 

  60. Lutzeyer W, Rübben H, Dahm H (1982) Prognostic parameters in superficial bladder cancer: an analysis of 315 cases. J Urol 127: 250

    PubMed  CAS  Google Scholar 

  61. Matalon R, Dorfman A (1966) Hurler’s syndrome — biosynthesis of acid mucopolysaccharides in tissue culture. Proc Natl Acad Sci USA 56: 1310

    PubMed  CAS  Google Scholar 

  62. Matalon R, Dorman A (1968) The structure of acid mucopolysaccharides produced by Hurler fibroblasts in tissue culture. Proc Natl Acad Sci USA 60: 179

    PubMed  CAS  Google Scholar 

  63. Matsumisha M, Bryan GT (1980) Early induction of mouse urinary bladder ornithine decarboxylase activity by rodent vesical carcinogens. Cancer Res 40: 1897

    Google Scholar 

  64. Monis B, Dorfman HD (1967) Some histochemical observation in transitional epithelium of man. J Histochem Cytochem 15: 475

    PubMed  CAS  Google Scholar 

  65. Motomija Y, Yamada K, Mutsushima S, Ijyuin M, Irya K, Okajima E (1975) Studies on urinary isozymes of lactic dehydrogenase and beta-glucuronidase in patients with bladder tumors. Urol Res 3: 41

    Google Scholar 

  66. Motomija Y, Ohzono S, Shiomi T, Kondo T, Ijuin M, Okajima E (1979) Studies on lactic dehydrogenase of patients with urinary bladder tumors. Invest Urol 17: 120

    Google Scholar 

  67. Murphy WM, Nagy GK, Rao MK, Solway MS, Parija GC, Cox CE, Friedell GH (1979) “Normal” urothelium in patients with bladder cancer. A preliminary report from the national bladder cancer collaborative group A. Cancer 44: 1050

    Google Scholar 

  68. Nagatuska Y, Sato K, Ototani N, Yosizawa Z (1980) A Method of screening test for excretion pattern of urinary glycosaminoglycans and its application to normal human urine. Tohoku J Exp Med 132: 159

    Google Scholar 

  69. Nayak SK, O’Toole C, Price ZH (1977) A cell line from an anaplastic transitional cell carcinoma of human urinary bladder. Br J Cancer 35: 142

    PubMed  CAS  Google Scholar 

  70. Newman J, Hicks RM (1977) Detection of neoplastic and preneoplastic by combined scanning and transmission electron microscopy of urinary surface of human and rat bladders. Histopathol 1: 125

    CAS  Google Scholar 

  71. Nigam VN, Cantero A (1973) Polysaccharides in cancer: glycoproteins and glycolipids. Adv Cancer Res 20: 1

    Google Scholar 

  72. Ozzello L, Speer FD (1958) The mucopolysaccharides in the normal and diseased breast: their distribution and significance. Am J Pathol 34: 993

    PubMed  CAS  Google Scholar 

  73. Parsons CL, Greenspan C, Moore SW, Mulholland SG (1977) Role of surface mucin in primary antibacterial defense of bladder. Urology 9: 48

    PubMed  CAS  Google Scholar 

  74. Parsons CL, Mulholland SG (1978) Bladder surface mucin — its antibacterial effect against various bacterial species. Am J Pathol 93: 423

    PubMed  CAS  Google Scholar 

  75. Parsons CL, Shrom SH, Hanno PM, Mulholland SG (1978) Bladder surface mucin — examination of possible mechanisms for its antibacterial effect. Invest Urol 16: 196

    PubMed  CAS  Google Scholar 

  76. Parsons CL, Mulholland SG, Anwar H (1979) Antibacterial activity of bladder surface mucin duplicated by exogenous glycosaminoglycan (heparin). Infect Immun 24: 552

    PubMed  CAS  Google Scholar 

  77. Parsons CL, Anwar H, Stauffer C, Schmidt JD (1979) In vitro adherence of radioactively labeled Escherichia coli in normal and cystitis-prone females. Infect Immun 26: 453

    PubMed  CAS  Google Scholar 

  78. Parsons CL, Stauffer C, Schmidt JD (1980) Bladder-surface glycosaminoglycans: an efficient mechanism of environmental adaptation. Science 108: 605

    Google Scholar 

  79. Parsons CL, Pollen JJ (1982) Treatment of interstitial cystitis with sodium pentosanpolysulfate. American Urological Association, 77th Annual Meeting

    Google Scholar 

  80. Parsons CL (1982) Prevention of urinary tract infection by the exogenous glycosaminoglycan sodium pentosanpolysulfate. J Urol 127: 167

    PubMed  CAS  Google Scholar 

  81. Pastorini P, Milano G, Toubol J, Raymond G, Cambon P, Lalanne CM (1981) The diagnostic and prognostic value of urinary polyamine measurement in bladder cancer. Urol Res 9: 13

    PubMed  CAS  Google Scholar 

  82. Rasheed S, Gardner MB, Rongey RW, Nelson-Rees WA, Arnstein P (1977) Human bladder carcinoma: characterization of two new tumor cell lines and search for tumor viruses. J Natl Cancer Inst 58: 881

    PubMed  CAS  Google Scholar 

  83. Robertson WG, Peacock M, Nordin BEC (1973) Inhibitors of the growth and aggregation of calcium oxalate crystals in vitro. Clin Chim Acta 43: 31

    PubMed  CAS  Google Scholar 

  84. Rübben H, Friedrichs R, Stuhlsatz HW, Dahm HH, Lutzeyer W (1981) Glykosaminoglykananalyse urothelialer Blasenkarzinome. Verh-Ber Dtsch Ges Urol 32: 355

    Google Scholar 

  85. Rübben H, Friedrichs R, Stuhlsatz HW, Dahm HH, Lutzeyer W (1980) Biochemical analysis of GAG in urothelial bladder cancer cell lines. Abstracts of the Proceedings of the First Meeting of the European Society for Urological Oncology and Endocrinology, November 21–22, 1980 Rotterdam. In: The Prostate 1: 127

    Google Scholar 

  86. Rübben H, Friedrichs R, Stuhlsatz HW, Lutzeyer W (1982) Glykosaminoglykane in normalem Urothel, urothelialen Karzinomen and Zellinien menschlicher Blasenkarzinome. 6. Symposium fir Experimentelle Urologie, Bonn

    Google Scholar 

  87. Rübben H, Dahm HH, Lutzeyer W (1981) Rezidivhäufigkeit and Tumorprogession superfizialer Hamblasenkarzinome. Urologie [A] 20: 211

    Google Scholar 

  88. Rübben H, Lutzeyer W (1984) Epidemiologic etiologic and pathogenetic aspects. Clinical practice in urology: bladder cancer (im Druck)

    Google Scholar 

  89. Russel DH (1971) Increased polyamine concentrations in the urine of human cancer patients. Nature 233: 144

    Google Scholar 

  90. Saito H, Yamagata T, Suzuki S (1968) Enzymatic methods or determination of small quantities or isomeric cnondroitin sulfates. J Biol Chem 243: 1536

    PubMed  CAS  Google Scholar 

  91. Saito S (1973) Mucopolysaccharides of rat ascites hepatoma cells. Gann 64: 247

    PubMed  CAS  Google Scholar 

  92. Sallis JD, Lumley MF (1979) On the possible role of glycosaminoglycans as hatural inhibitors of calcium oxalate stones. Invest Urol 16: 296

    PubMed  CAS  Google Scholar 

  93. Sampaio LO, Dietrich CP, Filho OG (1977) Changes in sulfated mucopolysaccharide composition of mammalian tissues during growth an in cancer tissues. Biochim Biophys Acta 498: 123

    PubMed  CAS  Google Scholar 

  94. Sanford EJ, Drago JR, Rohner TJ, Kessler GF, Sheehan L, Lipton A (1975) Preliminary evaluation of urinary polyamines in the diagnosis of genitourinary malignancy. J Urol 113: 218

    PubMed  CAS  Google Scholar 

  95. Senda H (1970) Studies of ß-glucuronidase and DNA synthesis activities in bladder tumors. Nagoya J Med Sci 33: 203

    Google Scholar 

  96. Schmidt JD (1966) Significance of total urinary lactic dehydrogenase activity in urinary tract disease. J Urol 96: 950

    PubMed  CAS  Google Scholar 

  97. Shrom SH, Parsons CL, Mulholland SG (1977) Role of urothelial surface mucoprotein in intrinsic bladder defense. Urology 9: 526

    PubMed  CAS  Google Scholar 

  98. Siegenthaler W (Hrsg) (1976) Klinische Pathophysiologie. Thieme, Stuttgart, S 500, 3. Aufl

    Google Scholar 

  99. Soto EA, Friedell GH, Tiltman AJ (1977) Bladder cancer as seen in giant histologic sections. Cancer 39: 447

    PubMed  CAS  Google Scholar 

  100. Starck D (1975) Embryologie. Thieme, Stuttgart, S 526

    Google Scholar 

  101. Stiller D (1964) Histochemische Untersuchungen über Sekretionserscheinungen in Papillomen und Karzinomen der Harnblase. Beitr Pathol Anat 129: 377

    PubMed  CAS  Google Scholar 

  102. Suzuki S, Saito H, Yamagata T, Anno K, Seno N, Kawai Y, Furuhashi T (1968) Formation of three types of disulfated disaccharides from chondroitin sulfates by chondroitinase digestion. J Biol Chem 243: 1543

    PubMed  CAS  Google Scholar 

  103. Takeuchi J (1971) Effect of chondroitinsulfate on the growth of solid Ehrlich aszites tumor after rechallenge and in vitro incubation. Gann 62: 337

    PubMed  CAS  Google Scholar 

  104. Varadi DP, Cifonelli JA, Dorfman A (1967) Acid mucopolysaccharides in normal urine. Biochim Biophys Acta 141: 103

    PubMed  CAS  Google Scholar 

  105. Wajsman Z, Merrin CE, Chu TM, Moore RH, Murphy GP (1975) Evaluation of biological markers in bladder cancer. J Urol 114: 879

    PubMed  CAS  Google Scholar 

  106. Webb KS, Stone KR, Sharief Y, Paulson DF (1980) Surface proteins of a transitional carcinoma cell line (KS 31 E). Urol Res 8: 77

    PubMed  CAS  Google Scholar 

  107. Worowsky K, Farbiszewsky R (1972) Studies on the proteolytic enzyme inhibitors in malignant neoplastic diseases. Pol Med J 11: 502

    Google Scholar 

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  1. Abteilung Urologie, Medizinische Fakultät, RWTH Aachen, Goethestraße 27/29, D-5100, Aachen, Deutschland

    H. Rübben, R. Friedrichs & W. Lutzeyer

  2. Abteilung Klinische Chemie und Pathobiochemie, Medizinische Fakultät, RWTH Aachen, Pauwelsstr., Aachen, D-5100, Deutschland

    H. W. Stuhlsatz

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  1. H. Rübben
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  1. Abteilung für Urologie, Eberhard-Karls-Universität Tübingen, Calwer Straße 7, D-7400, Tübingen 1, Deutschland

    Karl-Horst Bichler (Lehrstuhl) & Rolf Harzmann (Lehrstuhl) & 

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Rübben, H., Friedrichs, R., Stuhlsatz, H.W., Lutzeyer, W. (1984). Glykosaminoglykane in Harnblasenkarzinomen. In: Bichler, KH., Harzmann, R. (eds) Das Harnblasenkarzinom. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69535-3_14

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