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Methods to Estimate the Genetic Risk

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Book cover Mutations in Man

Abstract

In this chapter those effects are considered that may be inherited through radiation- or chemically-induced injury to the genes or chromosomes of germ cells. Mutational changes represent a broad spectrum of alterations in the deoxyribonucleotide structure of the genes. At one end of the spectrum this change can be represented by a single nucleotide base substitution, base addition or deletion. At the other end of the mutation spectrum is a complete deletion of the entire gene and/or adjacent genes. For higher organisms these submicroscopic changes are not further resolvable in many instances, and they are simply classified as mutations.

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Authors and Affiliations

  1. Institut für Genetik, Gesellschaft für Strahlen- und Umweltforschung (GSF), 8042, Neuherberg, Germany

    U. H. Ehling

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  1. U. H. Ehling
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Editors and Affiliations

  1. Institut für Genetik, Freie Universität Berlin, Arnimallee 5-7, 1000, Berlin 33, Germany

    Günter Obe

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© 1984 Springer-Verlag Berlin Heidelberg

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Ehling, U.H. (1984). Methods to Estimate the Genetic Risk. In: Obe, G. (eds) Mutations in Man. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69530-8_13

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  • DOI: https://doi.org/10.1007/978-3-642-69530-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69532-2

  • Online ISBN: 978-3-642-69530-8

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