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Monoamines and the Pathophysiology of Seizure Disorders

  • Chapter
Antiepileptic Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 74))

Abstract

One of the ways of understanding the pathophysiology of seizure disorders is by learning about the effects of the various factors that modulate susceptibility to seizures in experimental conditions. Obviously, neurochemical factors come into prominence here, and among them neuromediators attract especial interest. In this chapter, some of these will be reviewed, namely the monoamines, i.e., the catecholamines (noradrenaline and dopamine) serotonin (5-hydroxytrytamine), and histamine.

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Authors
  1. E. PrzegaliƄski
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  1. Laboratorium fĂŒr Pharmakologie und Toxikologie Fachbereich VeterinĂ€rmedizin, Freie UniversitĂ€t Berlin, Koserstraße 20, D-1000, Berlin 33, Germany

    Hans-Hasso Frey

  2. Abteilung fĂŒr Neurologie, Klinikum Charlottenburg, Spandauer Damm 130, D-1000, Berlin 19, Germany

    Dieter Janz

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PrzegaliƄski, E. (1985). Monoamines and the Pathophysiology of Seizure Disorders. In: Frey, HH., Janz, D. (eds) Antiepileptic Drugs. Handbook of Experimental Pharmacology, vol 74. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69518-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-69518-6_5

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