The Transport Carrier Principle

  • W. D. Stein
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 70 / 1)


The transport of metabolites across the intestinal epithelium has been a subject of absorbing interest to physiologists and pharmacologists for over a century. This present chapter deals with the carrier concept as applied to intestinal absorption, especially of sugars and amino acids. In this first section we shall consider the historical aspects of the development of the carrier concept and its elaboration for the understanding of intestinal absorption processes; Sect. B deals with the kinetics of carrier transport, while Sect. C is concerned with the efficiency and, hence, the energetics of carrier transport in absorbing systems.


Equilibrium Exchange Unidirectional Flux Cotransport System Transport Enzyme Carrier Model 
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© Springer-Verlag Berlin Heidelberg 1984

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  • W. D. Stein

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