Protein-Mediated Epithelial Iron Transfer

  • H. Huebers
  • W. Rummel
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 70 / 1)


Iron, the fourth most abundant element of the Earth’s crust, is unsurpassed in its versatility as a biologic catalyst (Aisen 1977). The adult human being contains 3–4 g total body iron of which the majority is present in circulating hemoglobin (Hughes 1980). The second largest fraction of iron within the body is storage iron in the form of ferritin and hemosiderin. Essential tissue iron is present in myoglobin and in the cell enzymes. Only 4 mg iron is bound to plasma transferrin whose important function is iron transport and exchange between body tissues.


Iron Deficiency Iron Absorption Iron Binding Iron Binding Protein Intestinal Iron Absorption 
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© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • H. Huebers
  • W. Rummel

There are no affiliations available

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