Successful heart-lung transplantation has now been accomplished in the clinical setting. Experimental work in this field began some 40 years ago, and there were even sporadic attempts at clinical application, but it was not until currently available immunosuppressive techniques were developed that this procedure became a clinical reality. This paper reviews experimental work to date, prior attempts at clinical heart-lung transplantation, the Stanford clinical series to the present, and the important aspects of management of these patients.
KeywordsLung Transplantation Rejection Episode Bronchial Artery Primary Pulmonary Hypertension Donor Lung
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- 1.Demikhov VP (1962) Some essential points of the techniques of transplantation of the heart, lungs, and other organs. In: Experimental transplantation of vital organs, Chap II. Medgiz State Press for Medical Literature, Moscow, pp 29–48Google Scholar
- 2.Neptune WB, Cookson BA, Bailey CP, Appier R, Rajkowski F (1953) Complete homologous heart transplantation. Arch Surg 66: 174Google Scholar
- 4.Lower RR, Stofer RC, Hurley EJ, Shumway NE (1961) Complete homograft replacement of the heart and both lungs. Surg 50: 842Google Scholar
- 7.Castaneda AR, Arnar O, Schmidt-Habelman P, Moller JH, Zamora R (1972) Cardiopulmonary autotransplantation in primates. J Cardiovasc Surg 37: 523Google Scholar