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Skelettsystem

  • Chapter
Pathologie

Zusammenfassung

Das Knochengewebe des Menschen ist ein hochspezialisiertes Organ. Es zeichnet sich vor allem dadurch aus, daß es neben seiner Stützfunktion eine zentrale Rolle in der Regulation des Kalzium-Stoffwechsels spielt.

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Weiterführende Literatur

  • Dahlin DC (1973) Bone tumors. Thomas, Springfield-Illinois

    Google Scholar 

  • Delling G (1975) Endokrine Osteopathien. Fischer, Stuttgart

    Google Scholar 

  • Hesch RD, Hehrmann R (eds) (1979) Renale Osteopathie. Thieme, Stuttgart

    Google Scholar 

  • Jee WSS, Parfrtt AM (eds) (1981) Bone Histomorphometry, 3rd international workshop. Armour Montagu, Levallois

    Google Scholar 

  • Kuhlencordt F, Bartelheimer H (eds) (1980) Handbuch der inneren Medizin. VI/1 B. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Schinz HR, Baensch WE, Frommhold W, Glauner R, Uehlinger E, Wellauer J (eds) (1979) Lehrbuch der Röntgendiagnostik. Thieme, Stuttgart

    Google Scholar 

  • Spranger JW, Langer LO, Wiedemann HR (1974) Bone Dysplasias. Fischer, Stuttgart

    Google Scholar 

  • Weiss L, Gilbert HA (eds) (1981) Bone metastasis. Hall, Boston Massachusetts

    Google Scholar 

Anatomisch-physiologishe Vorbemerkungen

  1. Delling G (1973) Age-related bone changes. Current topics in pathology. 58,118–149

    Google Scholar 

  2. Frost HM (1966) The bone dynamics in osteoporosis and osteomalacia. Thomas, Springfield Illinois

    Google Scholar 

  3. Jee WSS, Parfitt AM (eds) (1981) Bone Histomorphometry. 3rd international workshop. Armour Montagu, Levallois

    Google Scholar 

  4. Nichols G, Wasserman RH (eds) (1971) Cellular mechanisms for calcium transfer and homeostasis. Academec Press, New York London

    Google Scholar 

  5. Anderson HC (1967) Electron microscopic studies of induced cartilage development and calcification. J cell Biol 35,81–93

    PubMed  CAS  Google Scholar 

  6. Anderson HC (1969) Vesicles associated with calcification in the matrix of epiphyseal cartilage. J Cell Biol 41,59–64

    PubMed  CAS  Google Scholar 

  7. Atkinson PJ (1967) Variation in trabecular structure of vertebrae with age. Calc Tiss Res 1:24–32

    CAS  Google Scholar 

  8. Adams DO (1974) The structure of mononuclear phagocytes differentiating in vivo. Ann J Pathol 76,17–48

    CAS  Google Scholar 

  9. Ali SY, Sajdera SW, Anderson HC (1970) Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage. Proc Nat Acad Sei USA 67,1513–1520

    CAS  Google Scholar 

  10. Baker M, Jowsey J (1967) Bone formation and resorption in normal human rib. Clin Orthop 52: 241–247

    Google Scholar 

  11. Baud CA, Auil E (1971) Osteocyte differential count in normal human alveolar bone. Actaanat 78:321–327

    CAS  Google Scholar 

  12. Baylink D, Stauffer M, Wergedah J, Rich C (1970) Formation, mineralization, and resorption of bone in vitamin D-deficient rats. Clin Invest 49:1122–1134

    Google Scholar 

  13. Baylink D, Wergedah J, Stauffer M (1971) Formation, mineralization, and resorption of bone in hypophosphatemic rats. J Clin Invest 50:2519–2530

    PubMed  CAS  Google Scholar 

  14. Bonnucci E (1967) Fine structure of early cartilage calcification, J Ultrastruct Res 20, 33–50

    Google Scholar 

  15. Bonnucci E (1974) The organic-inorganic relationship in bone matrix undergoing osteoclastic resorption. Calc Tiss Res 16, 13–36

    Google Scholar 

  16. Cameron DA (1961) The fine structure of osteoblasts in the meta- physis of the tibia of the young rat. J Biophys Biochem Cytol 9, 583–595

    PubMed  CAS  Google Scholar 

  17. Cameron DA (1972) The ultrastructur of bone. In: The Biochemistry and Physiology of Bone, Bourne GH (eds). Academic Press, New York London

    Google Scholar 

  18. Bordier PHI, Tun Chot S (1972) Quantitative histology of metabolic bone disease. Clin Endoer Metabol 1:197–215

    Google Scholar 

  19. Burkhardt R (1966) Präparative Voraussetzungen zur klinischen Histologie des menschlichen Knochenmarkes. Blut 14: 30–45

    PubMed  CAS  Google Scholar 

  20. Burkhardt R (1970) Farbatlas der klinischen Histopathologic von Knochenmark und Knochen. Springer, Berlin Heidelberg New York

    Google Scholar 

  21. Burkhardt R, Demmler K (1969) Altersveränderungen von Knochenmark und Knochen. Zschr Gerontol 2: 263–276

    Google Scholar 

  22. Cooper RR, Milgram JW, Robinson RA (1966) Morphology of the osteon. J Bone Jt Surg 148-A, 1239–1271

    Google Scholar 

  23. Delling G (1972) Über eine vereinfachte Methacrylateinbettung für unentkalkte Knochenschnitte. Beitr Path 145:100–105

    CAS  Google Scholar 

  24. Delling G (1979) Morphometrie des Knochengewebes. Verh Dtsch Ges inn Med 85: 225–239

    Google Scholar 

  25. Dequeker J, Remans J, Franssen R, Waes J (1971) Ageing pattern of trabecular and cortical bone and their relationship. Calc Tiss Res 7:23–30

    CAS  Google Scholar 

  26. Doty SB, Schoffield BH (1976) Enzyme histochemistry of bone and cartilage cells. Progr Histochem Cytochem 8. Fischer, Stuttgart

    Google Scholar 

  27. Dunnill MS, Anderson JA, Whitehead R (1967) Quantitative histological studies on age changes in bone. J Path Bact 94: 275–291

    PubMed  CAS  Google Scholar 

  28. Eger W, Gerner HJ, Kaemmerer H (1967) Bau und Dichte der menschlichen Spongiosa in Rippe, Wirbel und Becken als Ausdruck der statischen Funktion. Arch orthop Unfall-Chir 62: 97–112

    Google Scholar 

  29. Eger W, Goetz F, Kaemmerer H (1964) Herstellung von Dünnschliffen aus Knochen und Weichgewebe nach Markierung mit Tetracyclinen. Langenbecks Arch klin Chir 306:205–214

    CAS  Google Scholar 

  30. Fowler LJ, Bailey AJ (1972) Current concepts of the crosslinking in bone collagen. Clin Orthop 85:193–206

    PubMed  CAS  Google Scholar 

  31. Frost HM (1968) Tetracycline bone labeling in anatomy. Am J Phys Anthrop 29:183–196

    PubMed  CAS  Google Scholar 

  32. Frost HM (1963) Bone remodelling dynamics. Thomas, Springfield Illinois

    Google Scholar 

  33. Garn MS, Rohmann CG, Wagner B (1967) Bone loss as a general phenomenon in man. Fed Proc 26:1729–1736

    PubMed  CAS  Google Scholar 

  34. Goldner J (1938) A modification of the Masson trichrometechnique for routine laboratory purpose. Am J Path 14: 237–243

    PubMed  CAS  Google Scholar 

  35. Göthlin G, Ericsson JLE (1976) The osteoclast. Review of ultrastructure, origin and structure function relationship. Clin Orthop Rel Res 120:201–231

    Google Scholar 

  36. Hall BK (1975) The origin and fate of osteoclasts. Anat Ree 183: 1–12

    CAS  Google Scholar 

  37. Henning A (1956) Bestimmung der Oberfläche beliebig geformter Körper mit besonderer Anwendung auf Körperhaufen im mikroskopischen Bereich. Mikroskopie 11:1–20

    PubMed  CAS  Google Scholar 

  38. Höhling HJ, Steffens H, Ashton BA, Nicholson W (1974) Molecularbiologie der Hartgewebsbildung. Verh Dtsch Ges Path 58: 54–71

    Google Scholar 

  39. Holtrop M (1977) Quantitation of the ultrastructure of the osteoclast for the evaluation of cell function. In: Histomorphometry, Meunier JP (eds) pp 133–145. Soc de la nouvelle imprimerie Fournie: Toulouse

    Google Scholar 

  40. Holtrop ME, King GJ (1977) The ultrastructure of the osteoclast and its functional implications. Clin Orthop Rel Res 123: 177–196

    Google Scholar 

  41. Holtrop ME, Raisz LG, Simmons HA (1974) The effects of parathyroid hormone, colchizin and calcitonin on the ultrastructure and the activity of osteoclasts in organ culture. J Cell Biol 60: 346–355

    PubMed  CAS  Google Scholar 

  42. Iwata H, Urist MR (1972) Protein polysaccharide of bone morphogenetic matrix. Clin Orthop 87: 257–274

    PubMed  CAS  Google Scholar 

  43. Jande SS (1971) Fine structural study of osteocytes and their surrounding bone matrix with respect to their age in young chicks. J Ultrastructure Res 37:279–300

    CAS  Google Scholar 

  44. Jande SS (1972) Effects of parathormone on osteocytes an their bone matrix. Z Zellforsch 130:463–470

    PubMed  CAS  Google Scholar 

  45. Jande SS, Belanger LF (1971) Electron microscopy of osteocyte and the pericellular matrix in rat trabecular bone. Calc Tiss Res 6:280–289

    Google Scholar 

  46. Jee WSS, Kimmel DB (1977) Bone cell origin at the endosteal surface. In: Bone Histomorphometry, Meunier JP (eds). Soc de la nouvelle imprimerie Fournie: Toulouse

    Google Scholar 

  47. Jee WSS, Nolan PD (1963) Origin of osteoclasts from fusion of phagocytes. Nature 200: 225–226

    PubMed  Google Scholar 

  48. Knese KH (1972) Proteoglycane und Glykoproteine im Periost. Acta histochem 44:77–89

    PubMed  CAS  Google Scholar 

  49. Knese KH (1958) Knochenstruktur als Verbundbau. Thieme, Stuttgart

    Google Scholar 

  50. Martin JH, Matthews JL (1971) Mitochondrial granules in chondrocytes, osteoblasts and osteocytes. Clin Orthop Rel Res 68: 273–278

    Google Scholar 

  51. Merz WA, Schenk RK (1970) Quantitative structural analyse of human cancellous bone. Acta anat (Basel) 74:140–149

    Google Scholar 

  52. Merz WA, Schenk RK (1970) A quantitative histological study on bone formation in human cancellous bone. Acta anat 76:1–15

    PubMed  CAS  Google Scholar 

  53. Olah AJ, Schenk RK (1969) Veränderungen des Knochenvolumens und des Knochenanbaues in menschlichen Rippen und ihre Abhängigkeit von Alter und Geschlecht. Acta anat (Basel) 72:584–602

    CAS  Google Scholar 

  54. Owen M (1963) Cell population kinetics of an osteogenic tissue. J Cell Biol 19:19–32

    PubMed  CAS  Google Scholar 

  55. Owen M (1970) The origin of bone cells. In: International Review of Cytology, Bourne GH, Danielli GF (eds) Vol 28. Academic Press, New York, p 213

    Google Scholar 

  56. Owen M (1971) Cellular dynamics of bone. In: The physiology and biochemistry of bone, Bourne GH (eds) Vol 3. Academic Press, New York, pp 271–298

    Google Scholar 

  57. Owen M (1977) Precursors of osteogenic cells. Calc Tiss Res 24 (Suppl) 74

    Google Scholar 

  58. Parfitt AM (1982) The coupling of bone formation to bone resorption: A critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis, Metab Bone Disease Rel Res 4, 1–6

    CAS  Google Scholar 

  59. Schenk R (1974) Ultrastruktur des Knochens. Verh Dtsch Ges Path 58:72–82

    CAS  Google Scholar 

  60. Schenk RK, Merz WA (1969) Histologisch-morphometrische Untersuchungen über Altersatrophie und senile Osteoporose in der Spongiosa des Beckenkammes. Dtsch Med Wschr 94: 206–212

    PubMed  CAS  Google Scholar 

  61. Schenk RK, Merz WA, Müller J (1969) A quantitative histological study on bone resorption in human cacellous bone. Acta anat (Basel) 74:44–53

    CAS  Google Scholar 

  62. Schulz A, Donath K, Delling G (1973) Zur Ultrastruktur des Osteocyten in der Corticalis der Rattentibia. Verh Dtsch Ges Path 57:397

    CAS  Google Scholar 

  63. Talmage RV (1970) Morphological and physiological considerations in a new concept of calcium transport in bone. Am J Anat 129:467–476

    PubMed  CAS  Google Scholar 

  64. Ziegler R (1981) Pathophysiologic des Hyperparathyreoidismus. In: Hyperparathyreoidismus, Rothmund M (eds). Thieme, Stuttgart New York

    Google Scholar 

Entwicklungsstörungen des Skeletts

  1. Becker PE (1964) Humangenetik, Bad. II. Thieme, Stuttgart

    Google Scholar 

  2. Byers PH, Barsh GS, Holbrook KA (1982) Molecular Pathology in herited disorders at Collagen metabolism. Human Path 13: 89–95

    CAS  Google Scholar 

  3. Giedion A (1982) Skelettmanifestation von Stoffwechselerkrankungen. In: Schinz HR, Baensch WE, Frommhold W, Glauner W, Uehlinger E, Wellauer J. Lehrbuch der Röntgendiagnostik, Bd. II, Teil 2. Thieme, Stuttgart New York

    Google Scholar 

  4. Maroteaux P (1979) Bone disease of Children. JB Lippincott, Philadelphia Toronto

    Google Scholar 

  5. Pesch HJ, Spranger JW (1982) Angeborene Stoffwechselerkrankungen mit bevorzugter Lokalisation im Skelettsystem. Verh Dtsch Ges Path 66: 239–253

    CAS  Google Scholar 

  6. Spranger JW, Langer LO, Wiedemann HR (1974) Bone Dysplasias. Fischer, Stuttgart

    Google Scholar 

  7. Bonucci E, Del Marco A, Nicoletti B, Petrimelli P, Pozzi L (1976) Histological and Histochemical Investigation of Achondroplastic Mice: A possible Model of Human Achondroplasia. Growth 40:241–251

    PubMed  CAS  Google Scholar 

  8. Hyndman WB, Alexander DS, Mackie KW (1976) Chondrodystrophia Calcificans Congenita (The Conradi-Hunerman Syndrome). Clin Pediat 15: 317–321

    Google Scholar 

  9. Hwang WS, Tock EPC, Tan KL, Tan LKA (1979) The Pathology of Cartilage in Chondrodysplasias. J Path 127:11–18

    PubMed  CAS  Google Scholar 

  10. Lakatos I (1962) Chondrodystrophia fetalis bei einem von zweieiigen Zwillingen verschiedenen Geschlechts. Zentralbl Gyn 84: 698–702

    CAS  Google Scholar 

  11. Langer LO, Spranger JW, Greinacherl, HerdmanRC (1969) Thanatophoric Dwarfism. Radiology 92: 285–303

    PubMed  Google Scholar 

  12. Ornoy A, Sekelese, Smith P, Simkin A, Kohn G (1976) Achondrogenesis Typel in Three Sibling Fetuses. Am J Pathol 82: 71–84

    PubMed  CAS  Google Scholar 

  13. Passarge E, Wendel U, Wöhler W, Rüdiger HW (1974) Krankheiten infolge genetischer Defekte in lysosomalen Mukopolysaccharid-Abbau. Dtsch Med Wschr 99:1–15

    Google Scholar 

  14. Rimoin DL, Hughes GN, Kaufman RL, Rosenthal RE, McAlister WH, Silberberg R (1970) Enchondral Ossification in Achon- droplastic Dwarfism. New Engl J Med 283: 728–735

    PubMed  CAS  Google Scholar 

  15. Silberberg R, Hasler M, Lesker P (1976) Ultrastructure of Articular Cartilage Achondroplastice Mice. Acta anat 96:162–175

    PubMed  CAS  Google Scholar 

  16. Sillence DO, Horton WA, Rimoin DL (1979) Morphologie Studies in the Skeletal Dysplasias. Am J Path 96: 813–859

    PubMed  CAS  Google Scholar 

  17. Sillence DO, Senn A, Danks DM (1979) Genetic heterogenety in Osteogenesis imperfecta. J Med Gen 16:101–116

    CAS  Google Scholar 

  18. Silverman FN (1968) A differential diagnosis of achondroplasia. Rad Clin North Am 6: 223–237

    CAS  Google Scholar 

  19. Spranger J (1981) Klinische Diagnostik angeborener Stoffwechselstörungen. Monatsschr Kinderheilk 129: 554–555

    CAS  Google Scholar 

  20. Swoboda W (1969) Das Skelett des Kindes. Entwicklung, Fehlbildungen und Erkrankungen. Thieme, Stuttgart

    Google Scholar 

  21. Remmele W (1968) Die Osteopoikilie - Klinik, pathologische Anatomie, Differentialdiagnose. Ergebn allg Path path Anat 49, 183–228

    Google Scholar 

Spezille Wirbels?ulenerkrankungen

  1. Lennert K (1965) Pathologische Anatomie der Osteomyelitis. Verh Dtsch Orthop Ges 27–64

    Google Scholar 

  2. Maclntyre I (1976) Human calcitonin and Paget’s disease. Huber, Bern Stuttgart Vienna

    Google Scholar 

  3. Plaue R (1974) Die Behandlung der sekundär-chronischen Osteomyelitis. Enke, Stuttgart

    Google Scholar 

  4. Schenk RK (1973) Fracture Repair Overview. In: Calcified Tissue Proceedings, Ninth European Symposium on Calcified Tissues (eds) Czitober H, Eschberger J. Facta Publication Wien 13–22

    Google Scholar 

  5. Schinz HR, Baensch WE, Frommhold W, Glauner R, Uehlinger E, Wellauer J (eds) (1979) Lehrbuch der Röntgendiagnostik. Thieme, Stuttgart

    Google Scholar 

  6. Uehlinger E (1970) Die pathologische Anatomie der haematogenen Osteomyelitis. Chirurg 41:193–198

    PubMed  CAS  Google Scholar 

  7. Willert HG, Mueller K, Semlitsch M (1979) The Morphology of Polymethylmethacrylate (PMMA) Bone Cement. Arch Orthop Traumat Surg 94: 265–292

    CAS  Google Scholar 

  8. Ziegler R (1982) EHDT - Ein neues therapeutisches Prinzip bei Osteopathien und Calciumstoffwechselstörungen. Urban & Schwarzenberg, München Wien Baltimore

    Google Scholar 

  9. Zinn WM (ed) (1971) Idiopathic Ischemic Necrosis of the Femoral Head in Adults. Thieme, Stuttgart

    Google Scholar 

  10. Amako T, Kawashima M, Torisu T, Hayashi K (1974) Bone and joint lesions in ecompression sickness. Semin Arthritis Rheum 4 (2): 151–190

    PubMed  CAS  Google Scholar 

  11. Bach H (1976) Skelettveränderungen bei der Taucherkrankheit. Beitr Orthop Traumatol 23:306–313

    PubMed  CAS  Google Scholar 

  12. Bassett FH, Tindali JP (1972) Blastomycosis of Bone. Southern Med J, Vol 65,5:547–555

    PubMed  Google Scholar 

  13. Beck O, Soukup P (1972) Seltene Lokalisationen der juvenilen aseptischen Osteochondronekrosen. Beitr Orthop Traumatol 19: 592–600

    PubMed  CAS  Google Scholar 

  14. Bisaz S, Schenk R, Kunin AS, Russell GG, Mühlbauer R, Fleisch H (1975) The Comparative Effects of Vitamin D Deficiency and Ethane-l-Hydroxy-1, 1-Diphosphonate Ad ministation on the Histology and Glycolysis of Chick. Epiphyseal and Articular Cartilage. Calcif Tiss Res 19:139–152

    CAS  Google Scholar 

  15. Cserhati MD, Oliveira LG, Jacob HAC, Schreiber A (1979) Hi- stomorphological Investigations of Coxa Femoral Ends Following Double-Cup Arthroplasty According to Freeman. Arch Orthop Traumat Surg 94: 233–240

    CAS  Google Scholar 

  16. Decker S, Rehn J, v Düring M, Decker B (1976) Morphologischexperimenteller Beitrag zur Kenntnis der Vorgänge bei der Verpflanzung von autologer Beckenkammspongiosa bei Hunden. Arch orthop Unfall-Chir 85: 303–317

    CAS  Google Scholar 

  17. Doerr W (1974) Idiopathische Hüftkopfnekrose und Hyperurikämie. Verh Dtsch Ges Pathol 58:408–411

    PubMed  CAS  Google Scholar 

  18. Draenert K, Rudigier J (1978) Histomorphologie des Knochen- Zement-Kontaktes. Chirurg 49: 276–285

    PubMed  CAS  Google Scholar 

  19. Doyle FH, Woodhouse NJY, Glen ACA, Joplin GF, Maclntyre I (1974) Healing of the bones in juvenile Paget’s disease treated by human calcitonin. Brit J of Radiol 47: 9–15

    CAS  Google Scholar 

  20. Göthlin G, Arborgh B, Ericsson JLE, Helminen H (1973) Histochemical and Biochemical Studies on the Localization and Activity of Lysosomal. Enzymes in Fracture Callus. Histochem 35: 97–110

    Google Scholar 

  21. Hackett CJ (1975) An Introduction to Diagnostic Criteria of Syphilis, Treponarid and Yaws (Treponematoses) in Dry Bones, and Some Implications. Virchows Arch. A Path Anat and Histol 368:229–241

    CAS  Google Scholar 

  22. Hördegen KM, Kohne E, Lüdinghausen MV (1971) Zur Ätiologie der Legg-Calvé-Perthesschen Krankheit. Hämatologische, genetische und histologiache Untersuchungen. Münch Wschr 113:856–860

    Google Scholar 

  23. Lorenz M, Plenk J Jr (1977) Die Ultrastruktur der Zellen des Knochengewebes. Acta Med Austriaca, 4: 148–152

    PubMed  CAS  Google Scholar 

  24. Malkani K, Basle M, Rebel A (1976) Goniometrie Observation of Nuclear Inclusions in Osteoclasts in Paget’s Bone Disease. J Submicr Cytol 8 (2–3): 229–236

    Google Scholar 

  25. O’Neill JA, Meacham WF, Griffin PP, Sawyers JL (1973) Patterns of Injury in the Battered Child Syndrome. The Jorunal of Trauma, Vol 13,4:332–339

    Google Scholar 

  26. Rebel A, Malkani K, Basle M (1974) Anomalies nucléaires des ostéoclastes de la maladie osseuse de Paget. Nouv Presse méd 3 pp 1299–1301

    PubMed  CAS  Google Scholar 

  27. Reichelt A (1972) Neue Erkenntnisse auf dem Gebiet der Ätiologie und Pathogenese der juvenilen Osteochondrose der Tibiaapophyse (Osgood-Schlatter’sche Erkrankung). Med Welt 23: 1587–1590

    PubMed  CAS  Google Scholar 

  28. Riede UN, Ruedi TH, Rohner YLE, Perren S, Guggenheim R (1974) Quantitative und morphologische Erfassung der Gewebereaktion auf Metallimplantate (Osteosynthesematerial). Arch orthop Unfall-Chir 78:199–215

    CAS  Google Scholar 

  29. Schöttle H, Dallek M, Langendorff HU, Schöntag H, Jungbluth KH (1980) Heilung von Segmentdefekten an Röhrenknochen. Unfallchir 6,2:71–78

    Google Scholar 

  30. Tylkowski ChM, Wezeman FH, Ray RD (1976) Hormonal Effects on the Morphology of Bone Defect Healing. Clin Orthop Rel Res 115: 274–285

    CAS  Google Scholar 

  31. Uehlinger E (1964) Aseptische Knochennekrosen (Infarkte) nach Prednisonbehandlung. Schweiz Med Wschr 94:1527–1530

    PubMed  CAS  Google Scholar 

  32. Wolter D (1982) Osteolysen - Pathologische Frakturen. Thieme, Stuttgart New York

    Google Scholar 

Generalisierte Osteopathien

  1. Dambacher MA (1982) Praktische Osteologie. Thieme, Stuttgart New York

    Google Scholar 

  2. Delling G (1975) Endokrine Osteopathien. Fischer, Stuttgart

    Google Scholar 

  3. Franz HE (1981) Blutreinigungsverfahren. Thieme, Stuttgart New York

    Google Scholar 

  4. Hesch RD, Hehrmann R (eds) (1979) Renale Osteopathie. Thieme, Stuttgart

    Google Scholar 

  5. Kuhlencordt F, Bartelheimer H (eds) (1980) Handbuch der inneren Medizin VI/1 B. Springer, Berlin Heidelberg New York

    Google Scholar 

  6. Rothmund M (ed) (1980) Hyperparathyreoidismus. Thieme, Stuttgart New York

    Google Scholar 

  7. Adams PH, Jowsey J, Kelly PJ, Riggs L, Kenney VR, Jones JD (1967) Effects of hyperthyroidism on bone and mineral metabolism in man. Quart J Med 36:1–15

    CAS  Google Scholar 

  8. Aitken JM, Armstrong E, Anderson JB (1972) Osteoporosis after oophorectomy in the mature female rat and the effect of oestrogen and/or progeteron in its prevention. J Endocr 55: 79–87

    PubMed  CAS  Google Scholar 

  9. Aitken JM, Hart DM, Lindsay R, Anderson JB (1973) Factors influencing the respondsivness of the skeleton to oestrogen therapy in women after oophorectomy. Acta endocr (Kbh) Suppl 177/ 116

    Google Scholar 

  10. Albright F, Bloomberg E, Smith P (1940) Post-menopausal Osteo porose. Am Physiol 55: 298

    CAS  Google Scholar 

  11. Albright F, Reifenstein EC (1948) The parathyroid gland and metabolic bone disease. Selected studies Williams and Wilkens, Baltimore

    Google Scholar 

  12. Avioli LV, Birge SJ, Slatopolsky E (1969) The nature of vitamin D-resistance of patients with chronic renal disease. Arch Intern Med 124: 451–454

    PubMed  CAS  Google Scholar 

  13. Bullamore JR, Gallagher JC, Wilkinson R, Nordin BEC (1970) Effect of age on calcium absorption. Lancet II: 535–537

    Google Scholar 

  14. Byers PD, Smith R (1971) Quantitative histology of bone in hyperparathyroidism. Its relation to clinical features, x-ray, and biochemistry. Quart J Med 40:471

    PubMed  CAS  Google Scholar 

  15. Caniggia A, Gennari C (1972) Sites and modes of action of an estrogen-gestagen combination on calcium and phosphate metabolism in postmenopausal osteoprorosis. Clin Orthop Rel Res 85:184

    CAS  Google Scholar 

  16. Christiansen C, Kristensen M, Roedbro P (1972) Latent osteomalacia in epileptic patients on anticonvulsants. Brit Med J II: 738–739

    Google Scholar 

  17. Clark F, Simpson W, Young JR (1972) Osteomalacia in immigrants from the indian subcontinent in Newcastle upon Tyne. Proc roy Soc Med 65:14–16

    Google Scholar 

  18. Dent CE, Richens A, Rowe DJF, Stamp TCB (1970) Osteomalacia with long-term antikonsulvant therapy in epilepsy. Brit Med J 11:73

    Google Scholar 

  19. Duursma SA, Visser WJ, Nijo L (1972) A quantitative histological study of bone in 30 patients with renal insufficiency. Calc Tiss Res 9:216–225

    CAS  Google Scholar 

  20. Eger W (1965) Pathologische Anatomie der Osteoporose unter besonderer Berücksichtigung der Mineralstoffwechselvorgänge im Knochengewebe. Verh Dtsch Ges Inn Med 71: 533–568

    PubMed  CAS  Google Scholar 

  21. Erdheim J (1931) Über Wirbelsäulenveränderungen bei Akromegalie. Virch Arch path Anat 281:197

    Google Scholar 

  22. Fanconi A (1971) Idiopathische hypophasphatämische Osteomalazie mit Beginn in der Adoleszenz. Helv paediat Acta 26: 535–549

    PubMed  CAS  Google Scholar 

  23. Fanconi A, Prader A (1972) Hereditäre Rachitisformen. Schweiz Med Wschr 102:1073–1078

    PubMed  CAS  Google Scholar 

  24. Frame B, Foroozanfar F, Patton RB (1970) Normocalcemic primary hyperparathyroidism with osteitis fibrosa. Ann Int Med 73: 253–257

    PubMed  CAS  Google Scholar 

  25. Fukita T, Okuyama Y, Handa N, Orima H, Ohata M, Yoshikawa M, Akiyawa H, Kogure T (1971) Age - dependent bone loss after gastrectomy. J Am Geriat Soc 19: 840–846

    Google Scholar 

  26. Haas HG (1966) Knochenstoffwechsel- und Parathyreoidea-Erkrankungen. Thieme, Stuttgart

    Google Scholar 

  27. Hellström J (1962) Über die Prognose und pathologisch-anatomischen Veränderungen beim primären Hyperparathyreoidismus. Dtsch Med Wschr 87:121–125

    Google Scholar 

  28. Hövels O (1967) Rachitisprophylaxe. Mschr Kinderheilk 115: 492–493

    PubMed  Google Scholar 

  29. Krempien B, Ritz E, Heuck F (1971) Osteopathie bei Urämie. Verh Dtsch Ges Path 55: 821

    Google Scholar 

  30. Krempien B, Ritz E, Ditzen K, Hudelmeier G (1972) Über den Einfluß der Niereninsuffizienz auf Knochenbildung und Knochenresorption. Virch Arch Abt A Path Anat 355: 354–366

    CAS  Google Scholar 

  31. Kuhlencordt F (1970) Osteoporose. Verh Dtsh Ges Orthop 57: 221–226

    Google Scholar 

  32. Meema HE, Meema S (1968) Prevention of postmenopausal osteoporosis by hormone treatment of the menopause. Can Med Ass J 99: 248

    PubMed  CAS  Google Scholar 

  33. Mitchell ABS, Glass D, Gill AM (1971) Osteomalacia following vagotomy and pyloroplasty. Postgrad Med J 47:233–237

    PubMed  CAS  Google Scholar 

  34. Olah AJ (1973) Quantitative relations between osteoblasts and osteoid in primary hyperparathyroidism, intestinal melabsorption and renal osteodystrophy. Virch Arch Abt A Path Anat 358: 301–308

    CAS  Google Scholar 

  35. Parfitt AM (1971) The spectrum of hypoparathyroidism. J Clin Endocr Metab 34:152–158

    Google Scholar 

  36. Prader A (1973) Vitamin-D-resistente Rachitisformen. Mschr Kinderheilk 121: 348–353

    PubMed  CAS  Google Scholar 

  37. Recklinghausen F von (1891) Die fibröse und deformierende Ostitis. Die Osteomalacic und die osteoklastische Carcinose in ihren gegenseitigen Beziehungen. In Festschrift R Virchow zu seinem 71. Geburtstag. G Reimer, Berlin

    Google Scholar 

  38. Ritz E, Sieberth HG, Krempien B (1971) Ca-Stoffwechselstörungen bei chronischer Niereninsuffizienz. Klin Wschr 49: 1305–1314

    PubMed  CAS  Google Scholar 

  39. Uehlinger E (1973) Pathogenese und Struktur der Systemerkrankungen des Skeletts. Radiol 13: 88–93

    CAS  Google Scholar 

Sekundäre Knochentumoren

  1. Ackermann LV, Spjut HJ (1972) Tumors of bone and cartilage. Washington AFIP

    Google Scholar 

  2. Dahlin DC (1973) Bone tumors. Thomas, Springfield-Illinois

    Google Scholar 

  3. Dominok GW, Knoch HG (1971) Knochengeschwülste und geschwulstähnliche Knochenerkrankungen. VEB Fischer, Jena

    Google Scholar 

  4. Schajowicz F, Ackermann LV, Sissons HA (1972) Histological typing of bone tumors. WHO Genf

    Google Scholar 

  5. Schulz A (1980) Ultrastrukturpathologie der Knochentumoren. Progr Path 115. Fischer, Stuttgart New York

    Google Scholar 

  6. Weiss L, Gilbert HA (eds) (1981) Bone metastasis. Hall, Boston Massachusetts

    Google Scholar 

  7. Ackermann LV (1976) Common errors made by pathologists in the diagnosis of bone tumors. Ree Res Cancer Res 54,120–138

    Google Scholar 

  8. Adkins KF, Martinez MG, Robinson LH (1969) Cellular morphology and relationships in giant-cell lesions of the jaws, O. S., O.M.&O.P.28, (2), 216–222

    CAS  Google Scholar 

  9. Adler CP (1973) Knochencysten. Beitr Path 150,103–131

    CAS  Google Scholar 

  10. Adler CP (1974) Klinische und morphologische Aspekte maligner Knochentumoren. Dtsch Med Wschr 99,665–71

    Google Scholar 

  11. Aegerter EE, Kirkpatrick JA (1969) Tumor-like-processes (osteomas) pp 569–571. In Orthopaedic diseases. 3rd ed. Saunders & Comp, Philadelphia

    Google Scholar 

  12. Albright F, Scoville B, Wulkowitch HW (1938) Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and a gonadal dysfunction. Further observations including the report of two more cases. Endocrinology 22,411–421

    Google Scholar 

  13. Ameri MR, Zurbriggen S, Wagner HP (1974) Das solitäre eosinophile Granulom der Wirbelsäule (The solitary eosinophilic granuloma of the spine). Radiol clin biol 43,318–327

    PubMed  CAS  Google Scholar 

  14. Aparisi T, Arborgh B, Ericsson JLE (1977 a) Giant cell tumor of bone. Detailed fine structural analysis of different cell components. Virchows Arch Abt A 376,273–298

    CAS  Google Scholar 

  15. Aparisi T, Arborgh B, Ericsson JLE (1977b) Giant cell tumor of bone. Fine structural localization of acid phosphatase. Virch Arch Abt A 376,299–308

    CAS  Google Scholar 

  16. Aszodi K, Csato Z (1976) Aneurysmatische Knochencysten. Histologische Analyse von 15 Fällen. Arch orthop Unfallchir 84, 325–337

    PubMed  CAS  Google Scholar 

  17. Barnes R (1956) Aneurysmal bone cyst. J Bone Jt Surg (B) 38, 301–311

    Google Scholar 

  18. Battifora H (1970) Hemangiopericytoma: Ultrastructural study of five cases. Cancer 31,1418–1432

    Google Scholar 

  19. Becker W (1971) Zum Nomenklaturproblem bei den Knochentumoren. Zschr Orthop 108,476–490

    Google Scholar 

  20. Becker W (1974) Chondromyxoidfibrom des Knochens. Z Orthop 112, 333–336

    PubMed  CAS  Google Scholar 

  21. Bethke JFJ (1963) Hereditäre multiple Exostosen und ihre pathogenetische Deutung. Arch orthop Unfall-Chir 54,667–696

    Google Scholar 

  22. Biesecker JL, Marcove RC, Huvos AG, Mike V (1970) Aneurysmal bone cyst, a clinico-pathologic study of 66 cases. Cancer 26, 615–625

    PubMed  CAS  Google Scholar 

  23. Blauth W, Meves H (1976) Behandlungsprobleme bei der „aggressiven” Form der fibrösen Dysplasie. Zschr Orthopädie und ihre Grenzgebiete 112,231–235

    Google Scholar 

  24. Bloodgood JC (1910) Benign bone cysts, osteitis fibrosa. Ann Surg 52,145–166

    PubMed  CAS  Google Scholar 

  25. Bosch AL (1974) Non ossifying fibroma of bone. A histochemi- cal and ultrastructural characterization. Virch Arch A Path Anat 362,12–21

    Google Scholar 

  26. Broders AC (1940) The microscopic grading of cancer, in: Treatment of cancer and allied diseases (eds) Pack GT, Livingston EM. Vol I, pp 19–41. Paul Hoeber Inc, New York

    Google Scholar 

  27. Buring K (1975) On the origin of cells in heterotopic bone formation. Clin Orthop Rel Res 110, 293–302

    Google Scholar 

  28. Byers PD (1968) Solitary benign osteoblastic lesions of bone. Osteoid-osteoma and benign osteoblastoma. Cancer 22,43–57

    PubMed  CAS  Google Scholar 

  29. Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL (1948) Sarcoma arising in irradiated bone. Report of eleven cases. Cancer 1,3–29

    PubMed  CAS  Google Scholar 

  30. Cancilla PA, Lahey ME, Carnes WH (1967) Cutaneous lesions of Letterer-Sive disease Electron microscopic study. Cancer 20, 1986–1991

    PubMed  CAS  Google Scholar 

  31. Cline MJ, Golde DW (1973) A review and réévaluation of the histiocytic disorders. Am J Med 55,49–60

    PubMed  CAS  Google Scholar 

  32. Cocke WM, Wade WM (1970) Osteogenic sarcoma of the mandible. O.M., O.S. & O.P. 30 (5), 601–606

    Google Scholar 

  33. Codman EA (1931) Epiphyseal chondromatous giant cell tumor of the upper end of the humerus. Surggynec & Obst 52,543–548

    Google Scholar 

  34. Collins EM, Schmale MD, Kiersch ThA (1974) Chronic disseminated Histiocytosis X treated with vinblastine sulfate and prednisone. O. S., O. M. & O. P. 38,388–393

    CAS  Google Scholar 

  35. Dahlin DC (1956) Chondromyxoid fibroma of bone with emphasis on its morphological relationship to benign chondroblastoma. Cancer 9,195–203

    PubMed  CAS  Google Scholar 

  36. Dahlin DC (1975) Pathology of osteosarcoma. Clin Orthop Rel Res 111, 23–32

    Google Scholar 

  37. Dahlin DC, Cupps RE, Johnson EW (1970) Giant-Cell tumor: A study of 195 cases. Cancer 25,1061–1064

    PubMed  CAS  Google Scholar 

  38. Delling G, Schulz A, Seifert G (1978) Morphology of osteosarcoma: New qualitative and quantitative investigations. Path Res Pract 162,166–177

    PubMed  CAS  Google Scholar 

  39. Erlandson RA, Huvos AG (1974) Chondrosarcoma: A light and electron microscopic study. Cancer 34, (5) 1642–52

    PubMed  CAS  Google Scholar 

  40. Ewing J (1924) Endothelial myeloma of bone. Proc N Y Path Soc 24,93

    Google Scholar 

  41. Farr GH, Huvos AG, Marcove RC, Higinbotham NL, Foote FW (1974) Teleangiektatic osteogenic sarcoma. A revies of twenty- eight cases. Cancer 34,1150–1158

    PubMed  CAS  Google Scholar 

  42. Freeman AI, Sachafello C, Gaeta J, Shah NK, Wang JJ, Sinks LF (1972) An analysis of Ewing’s tumor in children at Roswell Park Memorial Institute. Cancer 29,1563–1569

    PubMed  CAS  Google Scholar 

  43. Friedman B, Gold H (1968) Ultrastructure of Ewing’s sarcoma of bone. Cancer 22,307–322

    PubMed  CAS  Google Scholar 

  44. Friedman B, Hanoaka H (1969) Langerhans cell granula in eosinophilic granuloma of bone. J Bone Jt Surg 51-A, 367–374

    Google Scholar 

  45. Friedman B, Hanoaka H (1971) Round cell sarcoma of bone - A light and electron microscopic study. J Bone Jt Surg 53-A, 1118–1136

    Google Scholar 

  46. Garrington GE, Scofield HH, Cornyn J, Hooker SP (1967) Osteosarcoma of the jaws. Cancer 20,377–391

    PubMed  CAS  Google Scholar 

  47. Henderson ED, Dahlin DC (1963) Chondrosarcoma of bone - A study of two hundred and eighty-eight cases. J Bone Jt Surg 45-A, 1450–1458

    Google Scholar 

  48. Henry A (1969) Monostotic fibrous dysplasia. J Bone Jt Surg 51-B,300–306

    Google Scholar 

  49. Huvos AG (1979) Bone tumors. Saunders, Philadelphia

    Google Scholar 

  50. Huvos AG, Marcove RC (1973) Chondroblastoma of bone: A critical review. Clin Orthop Rel Res 95,300–312

    Google Scholar 

  51. Jaffe HL (1935) „Osteoid-osteoma”. A benign osteoblastic tumor composed of osteoid and atypical bone. Arch Surg 31, 709–728

    Google Scholar 

  52. Jaffe HL (1943) Hereditary multiple exostoses. Arch Pathol 36, 335–357

    Google Scholar 

  53. Jaffe HL (1944) Giant-cell tumor problems of differential diagnosis. Bull Hosp Joint Dis 5,84

    Google Scholar 

  54. Kotz R, Salzer-Kuntschik M, Zweymüller K, Salzer M (1974) Therapy and prognosis of Ewing’s sarcoma. Österr Zschr Onkol 1,15–22

    Google Scholar 

  55. Levy WM (1976) Small round cell tumors of bone. In: Bones and Joints, Ackermann LV, Spjut HJ, Abell MR (eds) IAP-Mono-graph. Williams and Wilkins Corp, Baltimore, pp 312–319

    Google Scholar 

  56. Lichtenstein L (1964) Histiocytosis X (eosinophilic granuloma of bone, Letterer-Siwe Disease, and Schüller-Christian Disease). J Bone Jt Surg 46-A, 76–90

    Google Scholar 

  57. Lichtenstein L, Bernstein D (1959) Unusual benign and malignant chondroid tumors of bone. A survey of some mesenchymal cartilage tumors and malignant chondroblastic tumors including a few multicentric ones, as well as many atypical benign chondroblastomas and chondromyxoidfibromas. Cancer 12, 1142–1157

    Google Scholar 

  58. McKenna RJ, Schwinn CP, Soong KY, Higinbotham NL (1966) Sarcomata of the osteogenic series (osteosarcoma, fibrosarcoma, chondrosarcoma, parosteal osteogenic sarcoma, and sarcoma arising in abnormal bone). J Bone Jt Surg 48-A, 1–26

    Google Scholar 

  59. Pepe AJ, Kuhlmann RE, Miller DB (1977) Mesenchymal chondrosarcoma. J Bone Jt Surg 59-A, 256–258

    Google Scholar 

  60. Pritchard DJ, Dahlin DC, Dauphine RT, Taylor WF, Beabont JW (1975) Ewing’s sarcoma. A clinicopathological and statistical analysis of patients surviving five years or longer. J Bone Jt Surg 57-A, 10–16

    Google Scholar 

  61. Pritchard DJ, Finkel MP, Reilly CA (1975) The etiology of osteosarcoma. A review of current considerations. Clin Orthop 113, 14–22

    Google Scholar 

  62. Remagen W, Prein J (1975) Benign osteoblastoma. O.S., O.M. & O.P.39,279–283

    CAS  Google Scholar 

  63. Rosen G, Caparros B, Huvos AG, Kosloff C, Nirenberg A, Cacavio A, Marcove RC, Lane JM, Mehta B, Urban CH (1982) Preoperative Chemotherapy for Osteogenic Sarcoma: Selection of Postoperative Adjuvant Chemotherapy Based on the Response of the Primary Tumor to Preoperative Chemotherapy. Cancer 49, 1221–1230

    PubMed  CAS  Google Scholar 

  64. Salzer-Kuntschik M (1974) Zur Beurteilung von Probeentnahmen bei Knochentumoren. Verh Dtsch Ges Path 58,235–248

    CAS  Google Scholar 

  65. Salzer-Kuntschik M (1976) Cytologie and cytochemical behaviour of primary malignant bone tumors. Ree Res Cancer Res 54,145–156

    Google Scholar 

  66. Salzer M, Salzer-Kuntschik M (1965) Das Chondromyxoidfibrom. Langenbecks Arch Klin Chir 312,216–231

    CAS  Google Scholar 

  67. Salzer-Kuntschik M, Delling G, Sigmund R, Beron G (1983) Morphological Grades of Regression in Osteosarcoma after Polychemotherapy COSS 80. J Cancer Res Clin Oncol 106 (Suppl) 21–24

    PubMed  Google Scholar 

  68. Schajowicz F, Hokama J (1976) Aspiration (puncture or needle) biopsy in bone lesions. Ree Res Cancer Res 54,139–144

    Google Scholar 

  69. Schajowicz F, Lemos C (1970) Osteoid-osteoma and osteoblastoma. Acta orthop Scand 41,272–291

    PubMed  CAS  Google Scholar 

  70. Schajowicz F, Lemos C (1976) Malignant osteoblastoma. J Bone Jt Surg 58-B, 202–211

    Google Scholar 

  71. Schulz A, Delling G (1974) Vergleichende ultrastrukturelle Untersuchungen an osteogenen Knochentumoren: Osteom. Osteoblastom, Osteosarkom. Verh Dtsch Ges Path 58, 536

    CAS  Google Scholar 

  72. Schulz A, Maerker R, Delling G (1976) Das zentrale Riesenzell- granulom. Histochemische und ultrastrukturelle Untersuchungen zu Histogenese. Virchows Arch A Path Anat and Histol 370, 163–175

    CAS  Google Scholar 

  73. Schulz A, Delling G, Seifert G (1977) Ultrastrukturelle und mor- phometrische Untersuchungen an Osteosarkomen. Verh Dtsch Ges Path 61,465

    Google Scholar 

  74. Stein H, Kaiserling E, Lennert K (1974) Evidence for B-cell origin of reticulum cell sarcoma. Virchows Arch A Path Anat and Histol 364, 51–67

    CAS  Google Scholar 

  75. Uehlinger E (1940) Osteofibrosis deformans juvenilis (Polyostotische fibröse Dysplasie Jaffe-Lichtenstein). Virchows Arch 306, 255–299

    Google Scholar 

  76. Uehlinger E (1956) Pathogenese des primären und sekundären Hyperparathyreoidismus und der renalen Osteomalacic. Verh Dtsch Ges Inn Med 62,368–403

    Google Scholar 

  77. Uehlinger E (1959) Die pathologische Anatomie der Knochengeschwülste. Helv Chir Acta 26,597–620

    PubMed  CAS  Google Scholar 

  78. Uehlinger E (1975) Semimaligne Knochengeschwülste. Langenbecks Arch Chir 339,293–303

    PubMed  CAS  Google Scholar 

  79. Uehlinger E (1976) Primary malignancy, secondary malignancy, semimalignancy of bone tumors. Ree Res Cancer Res 54, 109–119

    Google Scholar 

  80. Unni KK, Dahlin DC, Beabout JW, Ivins JC (1976) Parosteal osteogenic osteosarcoma. Cancer 37,2466

    PubMed  CAS  Google Scholar 

  81. Unni KK, Dahlin DC, Beabout JW, Sim FH (1976) Chondrosarcoma: Clear cell variant. J Bone Jt Surg 58-A, 676–683

    Google Scholar 

  82. Von Recklinghausen F (1891) Die fibröse oder deformierende Ostitis, die Osteomalacic und die osteoplastische Carcinose in ihren gegenseitigen Beziehungen. In: Festschrift Rudolph Virchow zu seinem 71. Geburtstage, Reimer G, Berlin

    Google Scholar 

  83. Wassermann TH, Stuard ID (1974) Malignant fibrous histiocytoma with widespread metastases. Autopsy study. Cancer 33, 141–146

    Google Scholar 

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Delling, G. (1984). Skelettsystem. In: Remmele, W. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69456-1_9

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