Abstract
Previous studies have shown that afferent neurogenic stimuli from the surgical area are a major release mechanism of the endocrine-metabolic response to surgery [4]. Thus, neurogenic blockade by epidural analgesia with a local anesthetic is effective in inhibiting the stress response to lower abdominal surgery [3], but no studies are available comparing the influence of different analgesic techniques on the surgical stress response. This study summarizes the comparative effects of epidural morphine [2], preoperative application of epidural analgesia with a local anesthetic, posttraumatic application of epidural analgesia [5], and general anesthesia with systemically administered opiates on the adrenocortical and hyperglycemic response to surgery.
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References
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Christensen P, Brandt MR, Rem J, Kehlet H (1982) Influence of epidural morphine on the adrenocortical and hyperglycemic response to surgery. Br J Anaesth 54: 23
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Møller IW, Rem J, Brandt MR, Kehlet H (1982) The effect of posttraumatic epidural analgesia on the Cortisol and hyperglycemic response to surgery. Acta Anaesthesiol Scand 26: 56
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© 1984 Springer-Verlag Berlin Heidelberg
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Christensen, P., Møller, I.W., Rem, J., Brandt, M.R., Kehlet, H. (1984). Comparative Effects of Epidural Morphine and Epidural Analgesia with Local Anesthetic on the Endocrine-metabolic Response to Surgery. In: Wüst, H.J., Zindler, M., d’Arcy Stanton-Hicks, M. (eds) Neue Aspekte in der Regionalanaesthesie 3. Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine, vol 158. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69453-0_30
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DOI: https://doi.org/10.1007/978-3-642-69453-0_30
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-13023-9
Online ISBN: 978-3-642-69453-0
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