Clinical Survey of Spinal Anesthesia with Morphine

I Effects on Respiration and Pain Relief
  • C. B. Devaux
  • C. Tessier
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 158)


Morphine which is intrathecally administered interferes with the spinal function by inhibiting the liberation of P substances in the substantia. gelatinosa. The transmission of nociception is blocked at the spinal level [1–3, 7,14,11–13,17, 20, 21, 22]. On the basis of this evidence, it was possible to give spinal anesthesia with morphine for operations followed by very painful postoperative [5], used in this manner, morphine gives produces exceptional pain relief[7,17,18]. During animal and human trials of intrathecal application of morphine, endesired side effects were not noticed in animals and no narcotics dependence was senn in cancer patients [15,16,18,20,23].


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© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • C. B. Devaux
  • C. Tessier

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