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Buprenorphin als Monoanaesthetikum und in Kombination mit Bupivacain zur kontinuierlichen Epiduralanaesthesie

  • W. Haag
  • C. Louis
  • E. Hartung
  • E. Freye
Part of the Anaesthesiologie und Intensivmedizin Anaesthesiology and Intensive Care Medicine book series (A+I, volume 158)

Zusammenfassung

Buprenorphin, ein Abkömmling aus der Oripavinreihe (Abb. 1), interagiert als partieller Agonist-Antagonist [10] mit den Opiatrezeptoren, so daß die Substanz Analgesie auslösen kann. Pharmakologisch ist es etwa 40mal potenter als Morphin und zeichnet sich durch eine lange Analgesiedauer aus, die durch eine extrem langsame Dissoziation vom Opiatrezeptor zu erklären ist [9,14].

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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • W. Haag
  • C. Louis
  • E. Hartung
  • E. Freye

There are no affiliations available

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