Zusammenfassung
Der Ausdruck „Stenose“ beschreibt die Verringerung oder den totalen Verschluß eines Gefäßlumens. Stenosen sind häufig zurückzuführen auf intravaskuläre Ablagerungen, die an der Gefaßwand entstehen und von dort in das Lumen hineinragen (Atherosklerose). Das Auftreten einer arteriellen Stenose führt oft zu einer erheblichen Reduktion des Blutflusses zum distalen Gefaßbett, das von dieser Arterie versorgt wird. Besonders schwerwiegend sind die zirkulatorischen Störungen, die infolge einer verminderten Blutversorgung des Herzmuskels aufgrund einer Koronarstenose (Abb. 1) auftreten können (Angina pectoris, Herzinfarkt). Die vielen Aspekte dieses komplexen Problems sollen im Folgenden reduziert werden auf die Beschreibung der Wechselwirkung zwischen dem Blutfluß durch eine Arterie und der Stenose. Ein besonderes strömungstechnisches Problem hierbei ist die Wirkung einer Stenose auf den regionalen Blutfluß zu den peripheren Gefäßbetten.
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Schaper, W. (1984). Pathophysiologie der Koronardurchblutung. In: Roskamm, H., et al. Koronarerkrankungen. Handbuch der inneren Medizin, vol 9 / 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69451-6_3
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