Studies on health effects of environmental cadmium pollution have revealed that low molecular weight proteinuria, especially β2- microglobulinuria, was the earliest sign and itai-itai disease was the most advanced case. Dose-response relationship of environmental cadmium pollution was observed in three different cadmium-polluted areas and this suggested that the maximum allowable intake of cadmium might be very low, compared with nonpolluted levels of cadmium.


Cadmium Concentration Cadmium Exposure Akita Prefecture Nagasaki Prefecture Ishikawa Prefecture 
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Copyright information

© Dr. S. Bernhard, Dahlem Konferenzen, Berlin 1984

Authors and Affiliations

  • K. Nogawa
    • 1
  1. 1.Kanazawa Medical UniversityUchinada, IshikawaJapan

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