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TCGF-Dependent Growth of Naturally Autoreactive Cells: Regulatory Role of the Thymus

  • Conference paper
Hormonally Defined Media

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

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Abstract

Culture of non-immune spleen cells in the presence of T-cel1-growth-factor (TCGF) generate Natural Killer (NK) cells with autoreactive activity against syngeneic normal non-neoplastic cells. These cells are under thymic control. The possible relevance of these observations is discussed.

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References

  1. C. Riccardi, P. Puccetti, A. Santoni and R.B. Herberman., J. Natl. Cancer Inst., 63, 1041, 1979

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  2. C. Riccardi, A. Santoni, T. Barlozzari and R.B. Herberman. Cellular Immunology, 60, 136, 1981

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  3. C. Riccardi, B.M. Vose and R.B. Herberman., In “NK Cells and Other Natural Effector Cells” R.B. Herberman (Ed.) Academic Press, N.Y., 909, 1982

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  4. L.R. Ruben., In “Immune Regulation: Evolutionary and Biological Significance”. L.R. Ruben and M.E. Gershwin (Eds.) Marcel Dekker Inc. N.Y., vol. 17, 217, 1982

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Author information

Authors and Affiliations

  1. Institute of Pharmacology, University of Perugia, Italy

    Carlo Riccardi, Graziella Migliorati & Luigi Frati

  2. Institute of Pathology, University of Rome, Italy

    Carlo Riccardi, Graziella Migliorati & Luigi Frati

Authors
  1. Carlo Riccardi
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  2. Graziella Migliorati
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  3. Luigi Frati
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Editor information

Editors and Affiliations

  1. Institut für Neurobiologie, Universität Heidelberg, Im Neuenheimer Feld 504, 6900, Heidelberg 1, Germany

    G. Fischer

  2. Institut für Pharmakologie, Universität Mainz, Obere Zahlbacher Str. 67, 6500, Mainz, Germany

    R. J. Wieser

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© 1983 Springer-Verlag Berlin Heidelberg

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Riccardi, C., Migliorati, G., Frati, L. (1983). TCGF-Dependent Growth of Naturally Autoreactive Cells: Regulatory Role of the Thymus. In: Fischer, G., Wieser, R.J. (eds) Hormonally Defined Media. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69290-1_40

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  • DOI: https://doi.org/10.1007/978-3-642-69290-1_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69292-5

  • Online ISBN: 978-3-642-69290-1

  • eBook Packages: Springer Book Archive

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