Control of Behaviour and Growth by Imitating the Contact Environment

  • R. Wieser
  • G. Brunner
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


The behaviour of cells in vitro is the result of all the influences exerted by the actual microenvironment which, in a simplified form, is composed of two main compartments (Fig. 1): (i) the diffusive environment, (ii) the contact environment. These two compartments regulate the cell behaviour by distinct mechanisms induced by molecules which, beside being compartment-specific, differ in their mobility.


Glass Dish Contact Environment Diffusive Environment Contact Molecule Plasma Membrane Molecule 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • R. Wieser
    • 1
  • G. Brunner
    • 1
  1. 1.Institut für ImmunologieJohannes Gutenberg UniversitätMainzGermany

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