Intramuscular Ketamine: An Alternative Pain Treatment for use in Disasters?

  • W. Dick
  • W. K. Hirlinger
  • H. H. Mehrkens

Abstract

For more than 10 years, reports have been published on the analgesic effects of sub-anesthetic doses of ketamine [2– 6]. Clements et al. [1] recently tried to relate the analgesic effects of 0.5 mg/kg ketamine i.m. to the pharmacokinetic data. They reported that effective analgesia is present as soon as plasma levels of ketamine increase above the threshold level of 150 ng/ml.

Keywords

Diazepam Ketamine Halothane Dick Succinylcholine 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Clements JA, Nimmo WS (1981) Pharmacokinetics and analgesic effect of ketamine in man. Br J Anaesth 53:27PubMedCrossRefGoogle Scholar
  2. 2.
    Hagelin A, Lundberg D (1981) Ketamine for postoperative analgesia after upper abdominal surgery. Clin Ther 4:229–233PubMedGoogle Scholar
  3. 3.
    Parkhouse J, Mariott G (1977) Postoperative analgesia with ketamine and pethidine. Anaesthesia 32:285PubMedCrossRefGoogle Scholar
  4. 4.
    Sadove MS, Shulman M, Hatano S, Fevold N (1971) Analgesic effects of ketamine administered in subdissociative doses. Anesth Analg Cur Res 50:452Google Scholar
  5. 5.
    Saletu B, Saletu M, Brown M, Stern J, Sletten I, Ulett G (1975) Hypno-analgesia and acupuncture analgesia: A neurophysical reality? Neuropsychobiology 1:218PubMedCrossRefGoogle Scholar
  6. 6.
    Slogoff S, Allen GW, Wessels JV, Cheney DH (1974) Clinical experience with subanesthetic ketamine. Anesth Analg Cur Res 53:354Google Scholar

Copyright information

© Springer-Verlag Berlin, Heidelberg 1985

Authors and Affiliations

  • W. Dick
  • W. K. Hirlinger
  • H. H. Mehrkens

There are no affiliations available

Personalised recommendations