Intramuscular Ketamine: An Alternative Pain Treatment for use in Disasters?

  • W. Dick
  • W. K. Hirlinger
  • H. H. Mehrkens


For more than 10 years, reports have been published on the analgesic effects of sub-anesthetic doses of ketamine [2– 6]. Clements et al. [1] recently tried to relate the analgesic effects of 0.5 mg/kg ketamine i.m. to the pharmacokinetic data. They reported that effective analgesia is present as soon as plasma levels of ketamine increase above the threshold level of 150 ng/ml.


Pain Relief Analgesic Effect Enfl Urane Deltoid Muscle Emergency Condition 
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  1. 1.
    Clements JA, Nimmo WS (1981) Pharmacokinetics and analgesic effect of ketamine in man. Br J Anaesth 53:27PubMedCrossRefGoogle Scholar
  2. 2.
    Hagelin A, Lundberg D (1981) Ketamine for postoperative analgesia after upper abdominal surgery. Clin Ther 4:229–233PubMedGoogle Scholar
  3. 3.
    Parkhouse J, Mariott G (1977) Postoperative analgesia with ketamine and pethidine. Anaesthesia 32:285PubMedCrossRefGoogle Scholar
  4. 4.
    Sadove MS, Shulman M, Hatano S, Fevold N (1971) Analgesic effects of ketamine administered in subdissociative doses. Anesth Analg Cur Res 50:452Google Scholar
  5. 5.
    Saletu B, Saletu M, Brown M, Stern J, Sletten I, Ulett G (1975) Hypno-analgesia and acupuncture analgesia: A neurophysical reality? Neuropsychobiology 1:218PubMedCrossRefGoogle Scholar
  6. 6.
    Slogoff S, Allen GW, Wessels JV, Cheney DH (1974) Clinical experience with subanesthetic ketamine. Anesth Analg Cur Res 53:354Google Scholar

Copyright information

© Springer-Verlag Berlin, Heidelberg 1985

Authors and Affiliations

  • W. Dick
  • W. K. Hirlinger
  • H. H. Mehrkens

There are no affiliations available

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