Abstract
In this chapter discussion is limited to the different types of antimalarial drug combinations that have been described in experimental situations or for clinical use. The possible value of drug combinations in the prevention of drug resistance will be covered in Chap. 16. Combinations of drugs may be considered under several headings, namely those that are complementary (e.g. against different stages of a parasite), combinations that are additive but acting against the same stages and those that are synergistic. All have their place in the control of malaria. While this chapter is written within the context of “Novel Methods of Drug Development”, some of the older drug combinations will be referred to for the sake of completion and as a guide to future developments.
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Peters, W. (1984). Drug Combinations. In: Peters, W., Richards, W.H.G. (eds) Antimalarial Drug II. Handbook of Experimental Pharmacology, vol 68 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69254-3_6
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DOI: https://doi.org/10.1007/978-3-642-69254-3_6
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