Skip to main content
SpringerLink
Log in

Liquid-liquid Chromatography

  • Chapter
Practice of High Performance Liquid Chromatography

Part of the book series: Chemical Laboratory Practice ((CHEMICAL LABORA))

  • 978 Accesses

Abstract

In liquid-liquid chromatography the separation of the components of a mixture results from the distribution of the solutes between two immiscible liquids. One liquid is immobilized in the pores of a solid support and acts as the stationary phase. The other liquid, saturated with the stationary phase, is used as the mobile phase. Thus each phase in liquid-liquid chromatography can be considered as a bulk phase. This in contrast with bonded phase chromatography where only the mobile phase is a bulk phase.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Locke, D.C., Martire, D.E.: Analyt. Chem. 39, 921–925 (1967)

    Article  CAS  Google Scholar 

  2. Barton, A.F.M.: Chem. Rev. 75, 731–753 (1975)

    Article  CAS  Google Scholar 

  3. Pierotti, R.A.: Chem. Rev. 76, 718–726 (1976)

    Article  Google Scholar 

  4. Tijssen, R., Billiet, H.A. and Schoenmakers, P.J.: J. Chrom. 122, 185–203 (1976)

    Article  CAS  Google Scholar 

  5. Karger, B.L., Snyder, L.R.: J. Chrom. 125, 71–88 (1976)

    Article  CAS  Google Scholar 

  6. Tewari, Y.B., Martire, D.E., Wasik, S.P. and Miller, M.: J. Sol. Chem. 11, 435–445 (1982)

    Article  CAS  Google Scholar 

  7. Rohrschneider, L.: Analyt. Chem. 45, 1241–1247 (1973)

    Article  CAS  Google Scholar 

  8. Snyder, L.R.: J. Chrom. 92, 223–230 (1974)

    Article  CAS  Google Scholar 

  9. Snyder, L.R.: J. Chrom. Sci. 16, 223–234 (1978)

    CAS  Google Scholar 

  10. Rekker, R.F.: J. Chrom. 300, 109–125 (1984)

    Article  CAS  Google Scholar 

  11. Kirkland, J.J.: J. Chrom. Sci. 10, 593–599 (1972)

    CAS  Google Scholar 

  12. Huber, J.F.K. and Kraak, J.C., Veening, H.: Analyt. Chem. 44, 1554–1559 (1972)

    Article  CAS  Google Scholar 

  13. Huber, J.F.K. and van der Linden, R. and Ecker, E. and Oreans, M.: J. Chrom. 83, 267–277 (1973)

    Article  CAS  Google Scholar 

  14. Kirkland, J.J. and Dilks, C.H. Jr.: Analyt. Chem. 45, 1778–1781 (1973)

    Article  CAS  Google Scholar 

  15. Engelhardt, H., Asshauer, J., Neue, U. and Weigand, N.: Analyt. Chem. 46, 336–340 (1974)

    Article  CAS  Google Scholar 

  16. Berry, L.V. and Engelhardt, H.: J. Chrom. 95, 27–38 (1974)

    Article  CAS  Google Scholar 

  17. Parris, N.A.: J. Chrom. Sci. 12, 753–757 (1974)

    CAS  Google Scholar 

  18. Gonnet, C. and Rocca, J.L.: J. Chrom. 109, 297–303 (1975)

    Article  CAS  Google Scholar 

  19. Lindner, W. and Frei, R.W.: J. Chrom. 117, 81–86 (1976)

    Article  CAS  Google Scholar 

  20. Gonnet, C., Rocca, J.L.: J. Chrom. 120, 419–433 (1976)

    Article  CAS  Google Scholar 

  21. Durand, J.P. and Petroff, N.: J. Chrom. 190, 85–95 (1980)

    Article  CAS  Google Scholar 

  22. Nordlov, H., Jordan, P.M., Burton, G. and Scott, A.I.: J. Chrom. 190, 221–225 (1980)

    Article  CAS  Google Scholar 

  23. Wahlund, K.-G. and Edlen, B.: J. Liq. Chrom. 4, 309–323 (1981)

    Article  CAS  Google Scholar 

  24. Huber, J.F.K., Pawlovska, M., Markl, P.: Chromatographia 17, 653–663 (1983)

    Article  CAS  Google Scholar 

  25. Crombeen, J.P., Heemstra, S. and Kraak, J.C.: J. Chrom 282, 95–106 (1983)

    Article  CAS  Google Scholar 

  26. Mirrlees, M.S., Moulton, S.J., Murphey, C.T. and Taylor, P.J.: J. Med. Chem. 19, 615–619 (1976)

    Article  CAS  Google Scholar 

  27. Unger, K.K. (ed.): Porous Silica, Journal of Chromatography Library, vol. 16, Elsevier Pub. Comp., Amsterdam, Oxford, New York 1979, pp. 37, 48, 240

    Google Scholar 

  28. Halasz, I., Engelhardt, H., Asshauer, J. and Karger, B.L.: Analyt. Chem. 42, 1460–1461 (1970)

    Article  CAS  Google Scholar 

  29. Karger, B.L., Conroe, K. and Engelhardt, H.: J. Chrom. Sci. 242–250 (1970)

    Google Scholar 

  30. Crombeen, J.P., Heemstra, S., Kraak, J.C.: Chromatograpia 19, 219–224 (1984)

    Article  CAS  Google Scholar 

  31. Viricel, M. and Lemar, M.: J. Chrom. 116, 343–352 (1976)

    Article  CAS  Google Scholar 

  32. Hulshoff, A. and Perrin, J.H.: J. Chrom. 129, 263–276 (1976)

    Article  CAS  Google Scholar 

  33. Huber, J.F.K., Meijers, C.A.M. and Hulsman, J.A.R.J.: Analyt. Chem. 44, 111–116 (1972)

    Article  CAS  Google Scholar 

  34. Huber, J.F.K.: J. Chrom. Sci. 9, 72–76 (1971)

    CAS  Google Scholar 

  35. De Stefano, J.J. and Beachell, H.C.: J. Chrom. Sci. 8, 434–438 (1970)

    Google Scholar 

  36. Rossler, G. and Halasz, I.: J. Chrom. 92, 33–46 (1974)

    Article  Google Scholar 

  37. Horwitz, E.P., Bloomquist, C.A.A. and Delphin, W.H.: J. Chrom. Sci. 15, 41–46 (1977)

    CAS  Google Scholar 

  38. Huber, J.F.K.: Ber. Bunsenges. Phys. Chemie 77, 179–184 (1977)

    Google Scholar 

  39. Poppe, H., Kraak, J.C., Huber, J.F.K. and van den Berg, J.H.M.: Chromatographia 14, 515–523 (1981)

    Article  CAS  Google Scholar 

  40. Snyder, L.R.: Principles of Adsorption Chromatography, Marcel Dekker Inc., New York 1968, pp. 335–343

    Google Scholar 

  41. Kowalczyk, J.S. and Herbut, G.: J. Chrom. 196, 11–20 (1980)

    Article  CAS  Google Scholar 

  42. Sisco, W.R., Gilpin, R.K.: J. Chrom. Sci. 18, 41–45 (1980)

    CAS  Google Scholar 

  43. Crombeen, J.P., Heemstra, S. and Kraak, J.C.: J. Chrom. 286, 119–129 (1984)

    Article  CAS  Google Scholar 

  44. Engelhardt, H. and Weigand, N.: Analyt. Chem. 45, 1149–1154 (1973)

    Article  CAS  Google Scholar 

  45. Huber, J.F.K., Alderlieste, E.T., Harren, H. and Poppe, H.: Analyt. Chem. 45, 1337–1343 (1973)

    Article  CAS  Google Scholar 

  46. Kirkland, J.J.: J. Chrom. Sci. 7, 7–12 (1969)

    CAS  Google Scholar 

  47. Randau, D. and Schnell, W.: J. Chrom. 57, 373–381 (1971)

    Article  CAS  Google Scholar 

  48. Papa, L.J. and Turner, L.P.: J. Chrom. Sci. 10, 747–750 (1972)

    CAS  Google Scholar 

  49. Fitzpatrick, F.A. and Siggia, S., Dingman, J., Sr.: Analyt. Chem. 44, 2211–2216 (1972)

    Article  CAS  Google Scholar 

  50. Kraak, J.C.: Thesis, Amsterdam 1974

    Google Scholar 

  51. Waters, J.L., Little, J.N. and Horgan, D.F.: J. Chrom. Sci. 7, 292–296 (1969)

    Google Scholar 

  52. Vermont, J., Deleuil, M., De Vries, A.J. and Guillemin, C.L.: Analyt. Chem. 46, 1329–1337 (1975)

    Article  Google Scholar 

  53. Fishbein, L. and Albro, P.W.: J. Chrom. 70, 365–412 (1972)

    Article  CAS  Google Scholar 

  54. Rassi, Z.El, Gonnet, C. and Rocca, J.L.: J. Chrom. 125, 179–201 (1976)

    Article  Google Scholar 

  55. Huber, J.F.K., Hulsman, J.A.R.J. and Meijers, C.A.M.: J. Chrom. 62, 79–91 (1971)

    Article  CAS  Google Scholar 

  56. Muusze, R.G. and Huber, J.F.K.: J. Chrom. 83, 405–420 (1973)

    Article  CAS  Google Scholar 

  57. Stuurman, H.W. and Wahlund, K.-G.: J. Chrom. 218, 455–463 (1981)

    Article  CAS  Google Scholar 

  58. Mundschenk, H.: J. Chrom. 37, 431–452 (1968)

    Article  CAS  Google Scholar 

  59. Mundschenk, H.: J. Chrom. 38, 106–119

    Google Scholar 

  60. Mundschenk, H.: J. Chrom. 40, 393–409 (1969)

    Article  CAS  Google Scholar 

  61. Jentoft, R.E. and Gouw, T.H.: Analyt. Chem. 40, 923–927 (1968)

    Article  CAS  Google Scholar 

  62. Jentoft, R.E. and Gouw, T.H.: Analyt. Chem. 40, 1787–1790 (1968)

    Article  CAS  Google Scholar 

  63. Huber, J.F.K., Kolder, F.F.M. and Miller, J.M.: Analyt. Chem. 44, 105–110 (1972)

    Article  CAS  Google Scholar 

  64. Rickett, F.E.: J. Chrom. 60, 356–360 (1972)

    Article  Google Scholar 

  65. Morot-Gaudry, J.F., Nicol, M.Z. et Jolivet, E.: J. Chrom. 100, 206–210 (1974)

    Article  CAS  Google Scholar 

  66. Morot-Gaudry, J.F., Fiala, V., Huet, J.C. and Jolivet, E.: J. Chrom. 117, 279–284 (1974)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory for Analytical Chemistry, University of Amsterdam, Nieuwe Achtergracht 166, 1014 WV, Amsterdam, The Netherlands

    J. C. Kraak & J. P. Crombeen

Authors
  1. J. C. Kraak
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. P. Crombeen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Angewandte Physikalische Chemie, Universität des Saarlandes, D-6600, Saarbrücken, Germany

    Heinz Engelhardt

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Kraak, J.C., Crombeen, J.P. (1986). Liquid-liquid Chromatography. In: Engelhardt, H. (eds) Practice of High Performance Liquid Chromatography. Chemical Laboratory Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69225-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69225-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69227-7

  • Online ISBN: 978-3-642-69225-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation