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Cholinergics

  • P. L. Kaufman
  • T. Wiedman
  • J. R. Robinson
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 69)

Abstract

Cholinergic drugs can exert biological activity by modifying the normal mechanism of ACh-mediated autonomic neurotransmission in several ways (Fig. 1; Koelle 1975 a): interference with transmitter synthesis (hemicholinium); prevention of transmitter release (botulinum toxin); displacement of transmitter from ax-onal terminal (carbachol); mimicry of transmitter at postsynaptic receptor (methacholine, carbachol, nicotine); blockade of transmiter at postsynaptic receptor (atropine, D-tubocurarine, hexamethonium); inhibition of enzymatic breakdown of transmitter (anticholinesterases).

Keywords

Aqueous Humor Lacrimal Gland Cynomolgus Monkey Trabecular Meshwork Ciliary Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • P. L. Kaufman
  • T. Wiedman
  • J. R. Robinson

There are no affiliations available

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