ACTH and Grooming Behaviour in the Rat

  • B. Spruijt
  • W. H. Gispen
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

Over the last two decades, enormous progress has been made in understanding the role that neuropeptides play in brain and behaviour. Although neurochemists have isolated certain peptides from brain tissue, the studies on peptides and behaviour in fact were the first to demonstrate their important regulatory role in brain function. For instance, long before it was recognized that ACTH-like peptides could be found and synthesized in brain tissue, De Wied (1969) had shown that such peptides were able to affect adaptive behaviour through a direct central mechanism of action.

Keywords

Dopamine Morphine Explosive Histamine Clozapine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • B. Spruijt
  • W. H. Gispen
    • 1
  1. 1.Division of Molecular Neurobiology, Rudolf Magnus Institute for Pharmacology and Institute of Molecular BiologyState University of UtrechtUtrechtThe Netherlands

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