Hormonal Specificity and Activation of Social Behaviour in the Male Zebra Finch

  • C. F. Harding
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

It is now well established that the actions of testosterone (T) in both the brain and peripheral tissues are mediated by its conversion to active metabolites in the various target tissues. T is metabolized to a variety of 5a- and 513-reduced andr4ogens in avian peripheral tissues (Raith et al. 1977, Massa et al. 1980), and to these hormones and various oestrogens in the brain (Canard et al. 1978, Davies et al. 1980, Massa et al. 1977, Nakamura and Tanabe 1974). A question of primary importance is which of the many metabolites are active, causing changes in the target tissues, and which are merely steps in the degradation and excretion of T? In birds, as in mammals, 5a-reduced androgens, particularly 5a-dihydrotestosterone (5a-DHT), appear to be the active metabolites of T in peripheral target tissues including the cloacal or proctodeal gland of Japanese quail (Adkins et al. 1981, Massa et al. 1980), the comb of chickens (Balthazart and Hirschberg 1979), and the syrinx of songbirds (Lieberburg and Nottebohm 1979).

Keywords

Cholesterol Hydroxyl Estrogen Cage Testosterone 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adkins EK (1977) Effects of diverse androgens on the sexual behavior and morphology of castrated male quail. Horm Behav 8: 201–207PubMedCrossRefGoogle Scholar
  2. Adkins EK, Boop JJ, Koutnik DL, Morris JB, Pniewski EE (1981) Further evidence that androgen aromatization is essential for the activation of copulation in male quail. Physiol Behav 24: 441–446CrossRefGoogle Scholar
  3. Adkins-Regan E (1981) Effects of sex steroids on the reproductive behavior of castrated male ring doves. Physiol Behav 26: 561–565PubMedCrossRefGoogle Scholar
  4. Arai Y, Yamanouchi K, Mizukami S, Yanai R, Shibata K, Nagasawa H (1981) Induction of anovulatory sterility by neonatal treatment wtih 5i3dihydrotestosterone in female rats. Acta Endocrinol 96: 439–443PubMedGoogle Scholar
  5. Arnold AP (1975) The effects of castration and androgen replacement on song, courtship and aggression in zebra finches (Poephilaguttata). J Exp Zool 191: 309–325PubMedCrossRefGoogle Scholar
  6. Balthazart J, Hirschberg D (1979) Testosterone metabolism and sexual behavior in the chick. Horm Behav 12: 253–263PubMedCrossRefGoogle Scholar
  7. Balthazart J, Malacarne G, Deviche P (1981) Stimulatory effects of 5ßdihydrotestosterone on sexual behavior in the domestic chick. Horm Behav 15: 246–258PubMedCrossRefGoogle Scholar
  8. Callard GV, Petro Z, Ryan K (1978) Phylogenetic distribution of aromatase and other androgenconverting enzymes in the central nervous system. Endocrinology 103: 2283–2290PubMedCrossRefGoogle Scholar
  9. Cheng M-F, Lehrman DS (1975) Gonadal hormone specificity in the sexual behavior of ring doves. Psychoneuroendocrinology 1: 95–102CrossRefGoogle Scholar
  10. Davies DT, Massa R, James R (1980) Role of testosterone and of its metabolites in regulating gonadotropin secretion in the Japanese quail. J Endocrinol 84: 211–222PubMedCrossRefGoogle Scholar
  11. DeVoogd TJ, Nottebohm F (1981) Gonadal hormones induce dendritic growth in the adult avian brain. Science 214: 202–204PubMedCrossRefGoogle Scholar
  12. Guhl AM (1949) Heterosexual dominance and mating behavior in chickens. Behaviour 2: 102–120Google Scholar
  13. Gurney M, Konishi M (1980) Hormone-induced sexual differentiation of brain and behavior in zebra finches. Science 208: 1380–1383PubMedCrossRefGoogle Scholar
  14. Harding CF, Sheridan K, Walters MJ (1983) Hormonal specificity and activation of sexual behavior in the male zebra finch. Horm Behav 17: 111–133PubMedCrossRefGoogle Scholar
  15. Lieberburg I, Nottebohm F (1979) High-affinity androgen binding proteins in syringeal tissues of song birds. Gen Comp Endocrinol 37: 286–293PubMedCrossRefGoogle Scholar
  16. Luine V, Nottebohm F, Harding C, McEwen BS (1980) Androgen affects cholinergic enzymes in syringeal motor neurons and muscle. Brain Res 192: 89–107PubMedCrossRefGoogle Scholar
  17. Martini L (1982) The 5a-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications. Endocrinol Rev 3: 1–25CrossRefGoogle Scholar
  18. Massa R, Cresti L, Martini L (1977) Metabolism of testosterone in the anterior pituitary gland and the central nervous system of the European starling (Sturnus vulgaris). J Endocrinol 75: 347–354PubMedCrossRefGoogle Scholar
  19. Massa R, Davies DT, Bottoni L (1980) Cloacal gland of the Japanese quail: Androgen dependence and metabolism of testosterone. J Endocrinol 84: 223–230PubMedCrossRefGoogle Scholar
  20. McDonald PG, Doughty C (1974) Effect of neonatal administration of different androgens in the female rat: Correlation between aromatization and the induction of sterilization. J Endocrinol 61: 95–103PubMedCrossRefGoogle Scholar
  21. Morris D (1954) The reproductive behaviour of the zebra finch (Poephila guttata) with special reference to pseudofemale behaviour and displacement activities. Behaviour 6: 271–321CrossRefGoogle Scholar
  22. Nakamura T, Tanabe Y (1974) In vitro metabolism of steroid hormones by chicken brain. Acta Endocrinol 7 5: 410–416Google Scholar
  23. Nordeen EJ, Yahr P (1981) Activation and differentiation of sexual behavior and translocation of hypothalamic estrogen receptors in rats by 6-fluorotestosterone. Horm Behav 15: 123–140PubMedCrossRefGoogle Scholar
  24. Pietas RJ, Wenzel BM (1974) Effects of androgens on body weight, feeding and courtship behavior in the pigeon. Horm Behav 5: 289–302CrossRefGoogle Scholar
  25. Raith L, Bauer HJ, Karl HJ (1977) The extrahepatic metabolism of androgens in birds and mammals. Acta Endocrinol 84: 74–75Google Scholar
  26. Steimer T, Hutchison JB (1981) Metabolic control of the behavioral action of androgens in the dove brain: Testosterone inactivation by 5P-reduction. Brain Res 209: 180–204CrossRefGoogle Scholar
  27. Watson GH, Korach KS, Muldoon TG (1977) Obstruction of estrogen-receptor complex formation. Further analysis of the nature and steroidal specificity of the effect. Endocrinology 101: 1733–1743PubMedCrossRefGoogle Scholar
  28. Young CE, Rogers LJ (1978) Effects of steroidal hormones on sexual, attack and search behavior in the isolated male chick. Horm Behav 10: 107–117PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • C. F. Harding
    • 1
    • 2
  1. 1.Biopsychology ProgramHunter CollegeNew YorkUSA
  2. 2.Department of OrnithologyAmerican Museum of Natural HistoryNew YorkUSA

Personalised recommendations