The Effect of Autoclaving on Normal and Sarcomatous Bone Cells and on Graft Incorporation

Abstract

The use of autoclaved bone goes back to the early part of this century. Groves, in 1917, used autoclaved bone when he ran out of autogenous bone to complete his grafts. In 1938, Orell u.sed what he calls “Os Purum” in bone grafts. Later, the users of autoclaved bone believed that this procedure delayed graft incorporation (Odell et al, 1951; Reynolds and Oliver, 1950). In 1952, Lloyd-Roberts used autoclaved bone and stated that no immune reaction occurred when an autoclaved allogeneous graft was used. He thus refutes the conclusion that autoclaved bone delays graft incorporation.