The CSF Volume/Pressure Relationship in Man
When using the bolus method for assessing the volume/pressure properties of the cerebrospinal fluid space the calculations are often based on the assumption of a direct exponential relationship between volume and pressure. This implies that the rectilinear relationship between CSF pressure and elastance is assumed to pass through the origin. The present paper is aimed to test the hypothesis of such an exponential relation in normal man by studying the volume/pressure relationship by means of continuous CSF infusion over a wide range of pressures.
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