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Comparative Analysis of Interferon Structural Genes

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Interferons and Their Applications

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 71))

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Abstract

Interferons (IFNs) are a family of inducible proteins which exert potent biologic effects on target cells. These proteins render animal cells resistant to infection by a wide spectrum of viruses, inhibit cell proliferation and exert immunomodulatory effects on a variety of target cells (Sehgal et al. 1982). IFNs can be induced in a large number of different animal species (Stewart 1979) and usually exert their effects on cells of homologous species. However, certain IFNs are also active on cells of heterologous species (Stewart 1979).

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Authors
  1. P. B. Sehgal
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  2. A. D. Sagar
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Editor information

Editors and Affiliations

  1. HEM Research Inc., 12280 Wilkins Avenue, Rockville, MD, 20852, USA

    Paul E. Came Ph.D.

  2. Clinical Research, Department of Oncology, Orlowitz Cancer Institute, 230 North Broad Street, Philadelphia, PA, 19102, USA

    William A. Carter M.D. (Professor and Director) (Professor and Director)

  3. Department of Hematology and Oncology, Hahnemann University of Health Sciences, 230 North Broad Street, Philadelphia, PA, 19102, USA

    William A. Carter M.D. (Professor and Director) (Professor and Director)

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© 1984 Springer-Verlag Berlin Heidelberg

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Sehgal, P.B., Sagar, A.D. (1984). Comparative Analysis of Interferon Structural Genes. In: Came, P.E., Carter, W.A. (eds) Interferons and Their Applications. Handbook of Experimental Pharmacology, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69178-2_4

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  • DOI: https://doi.org/10.1007/978-3-642-69178-2_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69180-5

  • Online ISBN: 978-3-642-69178-2

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