Skip to main content
SpringerLink
Log in

Prophylaxis of Cerebral Ischemic Damage From Vasospasm After Subarachnoid Hemorrhage

  • Chapter
Book cover Brain Protection

Abstract

Besides recurrent bleeding, cerebral vasospasm is a major complicating factor after subarachnoid hemorrhage (SAH) from cerebral aneurysm (20,21,33).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Allen GS, Gold LHA, Chon SN, French LA (1974) Cerebral arterial spasm Part 3: In vivo intracisternal production of spasm by serotonin and blood and its reversal by phenoxybenzamine. J Neurosurg 40:451–458

    Article  PubMed  CAS  Google Scholar 

  2. Anderson RGG (1972) cAMP and calcium ions in mechanical and metabolic response of smooth muscles: Influence of some hormones and drugs. Acta Physiol Scand (Suppl) 382

    Google Scholar 

  3. Auer LM, Gallhofer B, Ladurner G, Heppner F, Lechner H (1980) Spontan ver lauf und operative Behandlung intrakranieller Aneurysmen nach Subarachnoidalblutung. Wien Med Wschr 24:871–875

    Google Scholar 

  4. Auer LM (1981) Pial arterial vasodilation by intravenous nimodipine in cats. Drug Res 31:1423–1425

    CAS  Google Scholar 

  5. Auer LM, Ito Z, Suzuki A, Ohta H (1981) Topical administration of nimodipine for treatment of cerebral vasospasm after acute aneurysm surgery. In: Proc Int Symp Cerebrovascular Diseases: New trends in surgical and medical aspects. Gardone Riviera, p 82

    Google Scholar 

  6. Auer LM, Ito Z, Suzuki A, Ohta H (1982) Prevention of symptomatic vasospasm by topically applied nimodipine. Acta Neurochir 63:297–302

    Article  CAS  Google Scholar 

  7. Auer LM, Oberbauer RW, Schalk HV (1983) Human pial vascular reactions to intravenous nimodipine infusion during EC-IC bypass surgery. Stroke 14:210–213

    Article  PubMed  CAS  Google Scholar 

  8. Auer LM, Suzuki A, Yasui N (1982) Intraoperative topic nimodipine after aneurysm clipping. Neurochirugia (submittectfor publication)

    Google Scholar 

  9. Bär HP (1974) Cyclic nucleotides and smooth muscle. Adv Cyclic Nucleotide Res 4:195–237

    PubMed  Google Scholar 

  10. Brandt L, Andersson KE, Edvinsson L, Ljunggren B (1981) Effects of extracellular calcium and of calcium antagonists on the contractile responses of isolated human pial and mesenteric arteries. J Cereb Blood Flow Metabol 1:339–347

    Article  CAS  Google Scholar 

  11. Brawanski A, Gaab MR, Bockhorn J, Haubitz I (1982) Atraumatic rCBF measurement: An aid in the timing of surgery and the management of spasm following SAH. Acta Neurochir 63:43–51

    Article  CAS  Google Scholar 

  12. Edvinsson L, Andersson KE, Brandt L, Ljunggren B, MacKenzie ET, Skärby T, Young A (1981) Effects of Ca antagonists on cerebral blood vessels. J Cereb Blood Flow Metabol (Suppl 1) 1:S334–S335

    Google Scholar 

  13. Edvinsson L, Andersson KE, Brandt L, Högestätt E, Ljunggren B, Skärby T (1980) Studies of the effects of changes in extracellular calcium and potassium on cerebrovascular smooth muscle tone and of effects of various calcium antagonists on potassium contracted cerebral vessels. In: Betz E, Grote J, Heuser D, Wüllenweber R. Eds. Pathophysiol Pharmacotherapy Cerebrovasc Disorders. Witzstrock, Baden-Baden, pp 343–346

    Google Scholar 

  14. Ellis EF, Nies AS, Oates JA (1977) Cerebral arterial smooth muscle contraction by thromboxane Ky Stroke 8:480–483

    Article  PubMed  CAS  Google Scholar 

  15. Ellis EF, Wei EP, Kontos HA (1979) Vasodilatation of cat cerebral arterioles by prostaglandins D2, E2, G2 and I2. Am J Physiol 237:H381–H385

    PubMed  CAS  Google Scholar 

  16. Fisher CM, Kistler JP, Davis JM (1980) Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 6:1–9

    Article  PubMed  CAS  Google Scholar 

  17. Flamm ES, Yasargil MG, Ransohoff J (1972) Alteration of experimental cerebral vasospasm by adrenergic blockade. J Neurosurg 37:294–301

    Article  PubMed  CAS  Google Scholar 

  18. Flamm ES, Yasargil MG, Ransohoff J (1972) Control of cerebral vasospasm with parenteral phenoxybenzamine. Stroke 3:421–426

    Article  PubMed  CAS  Google Scholar 

  19. Flamm ES, Ransohoff J (1979) Subarachnoid hemorrhage and cerebral vasospasm. In: Pia HW, Langmaid CH, Zierski J. Eds. Cerebral Aneurysms. Springer, Berlin Heidelberg New York, p 152–155

    Google Scholar 

  20. French LA, Blade PS (1950) Subarachnoid haemorrhage and intracranial aneurysms. Lancet 1:459–466

    Google Scholar 

  21. Gallhofer B, Auer LM (1982) Spontaneous course after subarachnoid haemorrhage -evaluation of 109 patients. Acta Neurochir 63:67–70

    Article  CAS  Google Scholar 

  22. Gelmers HJ (1982) Effect of nimodipine (BAY e 9736) on postischaemic cerebrovascular reactivity, as revealed by measuring regional cerebral blood flow (rCBF). Acta Neurochir 63:283–290

    Article  CAS  Google Scholar 

  23. Harris RJ, Branston NM, Symon L (1982) The effect of a calcium antagonist on the formation of cerebral ischaemic oedema and ion homeostasis. Proc 5th Int Symp Brain Edema. Groningen, p 56

    Google Scholar 

  24. Hoffmeister F, Kazda S, Krause HP (1979) Influence of nimodipine (BAY e 9736) on the postischaemic changes of brain function. Acta Neurol Scand 60, Suppl 72, 358–359

    Google Scholar 

  25. Ito Z (1982) The microsurgical anterior interhemispheric approach suitably applied to ruptured aneurysms of the anterior communicating artery in the acute stage. Acta Neurochir 63:85–99

    Article  CAS  Google Scholar 

  26. Kazda S, Hoffmeister F (1979) Effect of some cerebral vasodilators on the postischaemic impaired cerebral reperfusion in cats. Arch Pharmacol Suppl 307, R43

    Google Scholar 

  27. Kazda S, Hoffmeister F (1980) Personal communication

    Google Scholar 

  28. Kazda S, Towart R (1980) Differences in the effect of the calcium antagonists nimodipine (BAY e 9736) and bencyclan on cerebral and peripheral vascular smooth muscle. Brit J Pharmacol 72:582P–583P

    Google Scholar 

  29. Kazda S, Towart R (1982) A new calcium antagonistic drug with a preferential cerebrovascular action. Acta Neurochir 63:259–265

    Article  CAS  Google Scholar 

  30. Kikuchi H (1981) Emergency operation of ruptured aneurysm. In: Int Symp Cerebrovasc Diseases: New trends in surgical and medical aspects. Gardone Riviera

    Google Scholar 

  31. Ljunggren B, Brandt L, Kagström E, Sundberg G (1981) Results of early operations for ruptured aneurysms. J Neurosurg 54:473–479

    Article  PubMed  CAS  Google Scholar 

  32. Ljunggren B, Brandt L (1982) The outcome of 100 consecutive cases of early aneurysm surgery. Acta Neurochir 63:215–219

    Article  CAS  Google Scholar 

  33. McKissock W, Paine KWE (1959) Subarachnoid haemorrhage. Brain 82:356–366

    Article  Google Scholar 

  34. Ohta H, Ito Z, Yasui N, Suzuki A (1982) Extensive evacuation of subarachnoid clot for prevention of vasospasm — effective or not? Acta Neurochir 63:111–116

    Article  CAS  Google Scholar 

  35. Pasqualin A, Da Pian R (1982) An analysis of vasospasm following early surgery for intracranial aneurysms. Acta Neurochir 63:153–159

    Article  CAS  Google Scholar 

  36. Pennink M, White RP, Crockarell JR (1972) Role of prostaglandin F~ in the genesis of experimental cerebral vasospasm. Angiographic study in dogs. J Neurosurg 37:398–406

    Article  PubMed  CAS  Google Scholar 

  37. Perret G, Nishika H (1966) Cerebral angiography. J Neurosurg 25:98–116, 467–490

    Article  PubMed  CAS  Google Scholar 

  38. Saito I, Ueda Y, Sano K (1977) Significance of vasospasm in the treatment of ruptured intracranial aneurysms. J Neurosurg 47:412–429

    Article  PubMed  CAS  Google Scholar 

  39. Saito I, Shigeno T, Aritake K, Tanishima T, Sano K (1979) Vasospasm assessed by angiography and computerized tomography. J Neurosurg 51:466–475

    Article  PubMed  CAS  Google Scholar 

  40. Sano H, Kanno T, Sinomiya Y, Katada K, Katoh Y, Nakagawa T, Adachi K (1982) Prospection of chronic vasospasm by CT findings. Acta Neurochir 63:23–30

    Article  CAS  Google Scholar 

  41. Sano K, Saito I (1978) Timing and indication of surgery for ruptured intracranial aneurysms with regard to cerebral vasospasm. Acta Neurochir 41:49–60

    Article  CAS  Google Scholar 

  42. Sano K, Saito I (1979) Indication and timing of operation and vasospasm. In: Pia HW, Langmaid CH, Zierski J. Eds. Cerebral Aneurysms. Springer, Berlin Heidelberg New York, pp 208–216

    Google Scholar 

  43. Shepherd AP, Mao CC, Jacobson ED et al (1973) The role of cyclic AMP in mesenteric vasodilatation. Microvasc Res 6:332–341

    Article  PubMed  CAS  Google Scholar 

  44. Somlyo AP, Somlyo AV, Smiesko V (1972) Cyclic AMP and vascular smooth muscle. Adv Cyclic Nucleotide Res 1:175–194

    PubMed  CAS  Google Scholar 

  45. Sundt TM, Onofrio BM, Merideth J (1973) Treatment of cerebral vasospasm from subarachnoid hemorrhage with isoproterenol and lidocaine hydrochloride. J Neurosurg 38:557–560

    Article  PubMed  Google Scholar 

  46. Suzuki J, Onuma T, Yoshimoto T (1979) Results of early operations on cerebral aneurysms. Surg Neurol 11:407–412

    PubMed  CAS  Google Scholar 

  47. Symon L, Harris RJ, Branston NM (1982) Calcium ions and calcium antagonists in ischaemia. Acta Neurochir 63:267–275

    Article  CAS  Google Scholar 

  48. Takemae T, Mizukami M, Kin H, Kawase T, Araki G (1978) Computed tomography of ruptured intracranial aneurysms in acute stage — relationship between vasospasm and high density on CT scan. Brain Nerve 30:861–866

    PubMed  CAS  Google Scholar 

  49. Tanaka K, Gotoh F, Muramatsu F et al (1980) Effects of nimodipine (BAY e 9736) on cerebral circulation in cats. Drug Res 30:1494–1497

    CAS  Google Scholar 

  50. Toda N, Shimizu K, Ohta T (1980) Mechanism of cerebral arterial contraction induced by blood constituents. J Neurosurg 53:312–322

    Article  PubMed  CAS  Google Scholar 

  51. Towart R (1982) The pathophysiology of cerebral vasospasm, and pharmacological approaches to its management. Acta Neurochir 63:253–258

    Article  CAS  Google Scholar 

  52. Triner L, Nahas GG, Vulliemoz Y et al (1971) Cyclic AMP and smooth muscle function. Ann NY Acad Sci 185:458–476

    Article  PubMed  CAS  Google Scholar 

  53. Weir B, Grace M, Hansen J, Rothberg C (1978) Time course of vasospasm in man. J Neurosurg 48:173–178

    Article  PubMed  CAS  Google Scholar 

  54. Wellum GR, Irvine TW, Zervas NR (1980) Dose responses of cerebral arteries of the dog, rabbit and man to human hemoglobin in vitro. J Neurosurg 53:486–490

    Article  PubMed  CAS  Google Scholar 

  55. Wilkins RH, Alexander JA, Odom GL (1968) Intracranial arterial spasm: A clinical analysis. J Neurosurg 29:121–134

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Universitätsklinik für Neurochirurgie, 8036, Graz, Austria

    L. M. Auer

Authors
  1. L. M. Auer
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung für Anaesthesiologie im Zentrum Chirurgie, Universität Heidelberg, Im Neuenheimer Feld 110, 6900, Heidelberg 1, Germany

    Klaus Wiedemann

  2. Institut für Pathochemie und Allgemeine Neurochemie im Zentrum Pathologie, Universität Heidelberg, Im Neuenheimer Feld 220-221, 6900, Heidelberg 1, Germany

    Siegfried Hoyer

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Auer, L.M. (1983). Prophylaxis of Cerebral Ischemic Damage From Vasospasm After Subarachnoid Hemorrhage. In: Wiedemann, K., Hoyer, S. (eds) Brain Protection. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69175-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69175-1_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69177-5

  • Online ISBN: 978-3-642-69175-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation