Neurotoxicity in Rats Dosed with Peppermint Oil and Pulegone
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 7)
Rats dosed with peppermint oil and pulegone up to 100 or 160 mg/kg body weight/day, respectively, in 28 days developed encephalopathy. Microscopically dose-related cyst-like spaces were found in the white matter of the cerebellum.
Key wordsPeppermint oil Pulegone Food flavouring Encephalopathy Rats
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© Springer-Verlag 1984