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Decreased Blood Levels of Ethanol and Acetaldehyde by S-Adenosyl-L-Methionine in Humans

  • C. Di Padova
  • R. Tritapepe
  • P. Rovagnati
  • M. Pozzoli
  • G. Stramentinoli
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 7)

Abstract

In view of the protective effects of SAM on alcohol-induced fatty liver degeneration, an investigation has been carried out to see if this compound accelerates the clearance of ethanol and acetaldehyde in humans. Both parameters were significantly lower after SAM, indicating the capability of exogenous SAM to favour the inactivation of ethanol without increasing blood levels of acetaldehyde.

Key words

Acetaldehyde Ethanol S-adenosyl L-methionine Blood level 

Abbreviations

SAM

S-adenosyl-L-methionine

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References

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • C. Di Padova
    • 1
  • R. Tritapepe
    • 2
  • P. Rovagnati
    • 1
  • M. Pozzoli
    • 2
  • G. Stramentinoli
    • 3
  1. 1.3rd Medical ClinicUniversity of Milan School of MedicineMilanItaly
  2. 2.3rd Surgical ClinicUniversity of Milan School of MedicineMilanItaly
  3. 3.BioResearch Co.Research LaboratoriesMilanItaly

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