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Animal Models

Group Report

  • Conference paper
Book cover The Origins of Depression: Current Concepts and Approaches

Part of the book series: Dahlem Workshop Reports Life Sciences Research Report ((DAHLEM LIFE,volume 26))

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Abstract

The opportunity to bring together a multidisciplinary group of scientists to consider the topic of animal models and their use in research on depression was unique. This report represents the deliberations of our group over a period of several days and should be considered as complementary to the four data-based papers dealing with details of specific animal model systems.

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References

  1. Colpaert, F.C., Lenaerts, F.M., Niemegeers, C.J.E., and Janssen, P.A.J. 1975. A critical study on Ro 4-1284 antagonism in mice. Arch. Int. Pharmacodyn. 215: 40–90.

    PubMed  CAS  Google Scholar 

  2. Gouret, C; Mocquet, G., Coston, A., and Raynaud, G. 1977. Interaction de divers psychotropes avec cinq effets de la reserpine chez la souris et chez le chat. J. Pharmacol. Paris 8: 330–350.

    Google Scholar 

  3. Hellhammer, D. 1983. Gehirn und Verhalten. Muenster, FRG: Aschendorff Publishing Co.

    Google Scholar 

  4. Hinde, R.A., and Spencer-Booth, Y. 1971. Effects of brief separation from mother on rhesus monkeys. Science 173: 111–118.

    Article  PubMed  CAS  Google Scholar 

  5. Hrdina, P.D., von Kulmiz, P., and Stretch, R. 1979. Pharmacological modification of experimental depression in infant macaques. Psychopharmacology 64: 89–93.

    Article  PubMed  CAS  Google Scholar 

  6. Jalfre, M., and Porsolt, R.D. 1982. Antidepressants and the limbic system. In Psychopharmacology of the Limbic System, eds. E. Zarifian and M.Trimble. New York: Wiley, in press.

    Google Scholar 

  7. Johnson, J., Sherman, A., Petty, F., Daylor, D., and Henn, F. 1982. Receptor changes in learned helplessness. Soc. Neurosci. Abst. 8:392.

    Google Scholar 

  8. Kaufman, I.C. 1977. Developmental considerations of anxiety and depression: Psychobiological studies in monkeys. In Psychoanalysis and Contemporary Science, ed. T. Shapiro, pp. 317–363. New York: International Universities Press.

    Google Scholar 

  9. Kaufman, I.C, and Rosenblum, L. 1967. The reaction to separation in infant monkeys: Anaclitic depression and conservation-withdrawal. Psychosom. Med. 29: 649–675.

    Google Scholar 

  10. Kling, A., and Steklis, H.D. 1976. A neural substrate for affiliative behavior in nonhuman primates. Bain Behav. Evol. 13: 216–238.

    Article  CAS  Google Scholar 

  11. Kokkinidis, L., Zacharko, R.M., and Predy, P.A. 1980. Postamphetamine depression of self-stimulation responding from the substantia nigra: reversal by tricyclic antidepressants. Pharmacol. Biochem. Behav. 13: 379–383.

    Article  PubMed  CAS  Google Scholar 

  12. Kraemer, G.W., and McKinney, W.T. 1979. Interactions of pharmacological agents which alter biogenic amine metabolism and depression. J.Affect. Dis. 1:33–54.

    Article  PubMed  CAS  Google Scholar 

  13. MacLennan, A.J., Drugan, R.C., Hyson, R.L., Maier, S.E., Madden, J., and Barchas, J.D. 1982. Corticosterone: A critical factor in an opioid form of stress-induced analgesia. Science 215: 1530–1532.

    Article  PubMed  CAS  Google Scholar 

  14. Margules, D.L. 1979. Beta-endorphin and endoloxone: hormones of the autonomic nervous system for the conservation or expenditure of bodily resources and energy in anticipation of famine or feast. Neurosci. Biobehav. Rev. 3: 155–162.

    Article  CAS  Google Scholar 

  15. Margules, D.L. 1981. Opioid and anti-opioid actions in the survival and reproduction of individuals. In Theory in Psychopharmacology, ed. S.J.Cooper, vol. 1, pp. 177–195. New York: Academic Press.

    Google Scholar 

  16. Mineka, S., and Suomi, S.J. 1978. Social separation in monkeys. Psychol. Bull. 85: 1376–1400.

    Article  PubMed  CAS  Google Scholar 

  17. Miyauchi, T., Kitada, Y., and Satoh, S. 1981. Effects of acutely and chronically administered antidepressants on the brain regional 3-methoxy-4-hydroxy-phenylethyleneglycol sulfate in the forced swimming rat. Life Sci. 29: 1921–1928.

    Article  PubMed  CAS  Google Scholar 

  18. Porsolt, R.D., Anton, G., Blavet, N., and Jalfre, M. 1978. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol. 47:379–391.

    Article  PubMed  CAS  Google Scholar 

  19. Porsolt, R.D., Berlin, A., Blavet, N., Deniel, M., and Jalfre, M. 1979. Immobility induced by forced swimming in rats: effects of agents which modify central catecholamine and serotonin activity. Eur. J. Pharmacol. 57: 201–210.

    Article  PubMed  CAS  Google Scholar 

  20. Porsolt, R.D., Bertin, A., and Jalfre, M. 1978. Behavioural despair in rats and mice: strain differences and the effects of imipramine. Eur. J. Pharmacol. 51:291–294.

    Article  PubMed  CAS  Google Scholar 

  21. Rasmussen, K.L.R., and Reite, M. 1982. Loss-induced depression in an adult macaque monkey. Am. J. Psychiat. 139: 679–681.

    PubMed  CAS  Google Scholar 

  22. Reite, M., Harbeck, R., and Hoffman, A. 1981. Altered cellular immune response following peer separation. Life Sci. 29: 1133–1136.

    Article  PubMed  CAS  Google Scholar 

  23. Reite, M., Short, R., Seiler, C; and Pauley, J.D. 1981. Attachment, loss, and depression. J. Child Psychol. Psychiat. 22: 141–169.

    Article  PubMed  CAS  Google Scholar 

  24. Robson, R.D., Antonaccio, M.J., Saelens, J.K., and Liebman,J. 1978. Antagonism by mianserin and classical a-adrenoceptor blocking drugs on some cardiovascular and behavioral effects of clonidine. Eur. J. Pharmacol. 47: 431–442.

    Article  PubMed  CAS  Google Scholar 

  25. Seligman, M.E.P. 1968. Chronic fear produced by unpredictable electric shock. J. Comp. Physiol. Psychiat. 66: 402–411.

    Article  CAS  Google Scholar 

  26. Sherman, A.D., and Petty, F. 1980. Neurochemical basis of the action of antidepressants on learned helplessness. Behav. Neur. Biol. 30: 119–134.

    Article  CAS  Google Scholar 

  27. Sherman, A.D., and Petty, F. 1982. Additivity of neurochemical changes in learned helplessness and imipramine. Behav. Neur. Biol., in press.

    Google Scholar 

  28. Southwick, C. 1967. Experimental studies of intra-group aggression in rhesus monkeys. Behaviour 28: 1–28.

    Article  Google Scholar 

  29. Spitz, R.A. 1946. Anaclytic depression. Psychoan. St. 2: 313–342.

    CAS  Google Scholar 

  30. Suomi, S.J., Seaman, S.F., Lewis, J.K., Delizio, R.D., and McKinney, W.T. 1978. Effects of imipramine treatment on separation-induced social disorders in rhesus monkeys. Arch. Gen. Psychiat. 35: 321–325.

    Article  PubMed  CAS  Google Scholar 

  31. Zetler, G. 1963. Die antikataleptische Wirksamkeit einiger Antidepressiva (Thymoleptica). Arzneim. Forsch. 13: 103–109.

    CAS  Google Scholar 

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Authors
  1. M. L. Reite
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  2. T. F. Anders
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  3. W. Greil
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  4. D. Hellhammer
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  5. F. A. Henn
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  6. R. J. Katz
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  7. I. C. Kaufman
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  8. G. W. Kraemer
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  9. M. Linden
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  10. M. T. McGuire
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  11. W. T. McKinney
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  12. G. Nissen
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  13. R. D. Porsolt
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Editor information

J. Angst

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© 1983 Berlin, Heidelberg, New York, Tokyo: Springer-Verlag.

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Reite, M.L. et al. (1983). Animal Models. In: Angst, J. (eds) The Origins of Depression: Current Concepts and Approaches. Dahlem Workshop Reports Life Sciences Research Report, vol 26. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69129-4_24

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  • DOI: https://doi.org/10.1007/978-3-642-69129-4_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69131-7

  • Online ISBN: 978-3-642-69129-4

  • eBook Packages: Springer Book Archive

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