Skip to main content
SpringerLink
Log in

Analgesics and Nonsteroidal Anti-Inflammatory Drugs

  • Chapter
Allergic Reactions to Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 63))

Abstract

The scarcity and high price of quinine during the last third of the nineteenth century motivated the search for synthetic antipyretics. As a result, a large number of compounds were introduced into medicine which share with cinchona the ability to produce antipyretic, analgesic, and anti-inflammatory effects (Woodbury and Fingl 1979). Of these, aspirin has become the most widely used drug in the world. Recently, there have been main reasons for the research in this area. First, the recognition of the value and the limitations of the adrenocorticosteroids for long-term therapy of inflammatory disorders. Second, the new possibilities of employing aspirin-like drugs in prevention and therapy of thromboembolic diseases.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ackroyd JF (1964) The diagnosis of disorders of the blood due to drug hypersensitivity caused by an immune mechanism. In: Ackroyd JF (ed) Immunological methods. Black-well, Oxford

    Google Scholar 

  • Adcock JJ, Garland LG, Moncada S, Salmon JA (1978) The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. Prostaglandins 16:179–189

    PubMed  CAS  Google Scholar 

  • Amos HE (1976) Allergic drug reactions. Arnold, London

    Google Scholar 

  • Anonymous (1974) Aspirin-induced hepatic injury. Ann Intern Med 80:103–105

    Google Scholar 

  • Anonymous (1979) Liver injury, drugs, and popular poisons. Br Med J 2:574–575

    Google Scholar 

  • Argov Z, Mastaglia (1979) Drug-induced peripheral neuropathies. Br Med M 1:663–665

    CAS  Google Scholar 

  • Badley BWD (1979) Phenazopyridine-induced hepatitis. Br Med J 2:850

    Google Scholar 

  • Barrett AJ, Weller E, Rozengurt N, Longhurst P, Humble JG (1976) Amidopyrine agranulocytosis: drug inhibition of granulocyte colonies in the presence of patient’s serum. Br Med J 2: 850–851

    PubMed  CAS  Google Scholar 

  • Basomba A, Romar A, Villamanzo, IG, Campos A (1976) The effect of sodium cromoglycate in preventing aspirin-induced bronchospasm. Clin Allergy 6:269–275

    PubMed  CAS  Google Scholar 

  • Bianco S, Robuschi M, Petrigni C (1977) Aspirin-induced tolerance in aspirin-asthma detected by a new challenge test. IRCS Med Sci Libr Compend 5:129

    Google Scholar 

  • Borgeat P, Samuelsson B (1979) Arachidonic acid metabolism in polymorphonuclear leukocytes. 3. Effects of ionophore — A 23187. Proc Natl Acad Sci USA 76:2148–2153

    PubMed  CAS  Google Scholar 

  • Brocq L (1894) Éruption érythèmato-pigmentée fixé due à l’antipyrine. Ann Dermatol Syphiligr 5:308–314

    Google Scholar 

  • Bundgaard H (1976) Colorimetric analysis of immunogenic impurities in acetylsalicylic acid. J Pharm Pharmacol 28:544–547

    CAS  Google Scholar 

  • Bundgaard H, de Weck AL (1975) The role of aminoreactive impurities in acetylsalicylic acid allergy. Int. Arch Allergy Appl Immunol 49:119–125

    CAS  Google Scholar 

  • Burka JF, Flower RJ (1979) Effects of modulators of arachidonic acid metabolism on the synthesis and release of slow-reacting substances of anaphylaxis. Br J Pharmacol 65:35–41

    PubMed  CAS  Google Scholar 

  • Ceserani R, Colombo M, Robuschi M, Bianco S (1978) Tartrazine and prostaglandin system. Prostaglandins Med 1:499–505

    PubMed  CAS  Google Scholar 

  • Chafee FH, Settipane GA (1974) Aspirin intolerance. I. Frequency in an allergic population. J Allergy Clin Immunol 53:193

    Google Scholar 

  • Czerniawska-Mysik G, Szczeklik A (1980) Allergy to pyrazolone drugs. Acta Med Pol

    Google Scholar 

  • Delaney JC (1973) Asthma, nasal polyposis and aspirin sensitivity. Ann Intern Med 79:761

    PubMed  CAS  Google Scholar 

  • Delaney JC (1976) The effect of sodium cromoglycate on analgesic-induced asthmatic reactions. Clin Allergy 6:365–370

    PubMed  CAS  Google Scholar 

  • Delaney JC, Kay AB (1976) Complement components and IgE in patients with asthma and aspirin idiosyncrasy. Thorax 31:425–427

    PubMed  CAS  Google Scholar 

  • D’Eshouges JR, Grigner P, Smadja A et al. (1961) Purpura thrombocytopenique aigü par sensibilisation à l’aspirine. Nouv Rev Fr Hematol 1:609–611

    Google Scholar 

  • de Weck AL (1971) Immunological effects of aspirin anhydride, a contaminant of commercial acetylsalicylic acid preparations. Int Arch Allergy Appl Immunol 41:393–398

    PubMed  Google Scholar 

  • Doeglas HMG (1975) Reactions to aspirin and food additives in patients with chronic urticaria, including the physical urticarias. Br J Dermatol 93:135–141

    PubMed  CAS  Google Scholar 

  • Drazen JM, Lewis RA, Wasserman SI, Orange RP, Austen FK (1979) Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guineapig tracheal spirals and parenchymal strips. J Clin Invest 63:1–5

    PubMed  CAS  Google Scholar 

  • Dry J, Pradalier A, Deveau A (1979) Urticaire et oedème de Quincke chroniques. Nouv Presse Med 8:211

    PubMed  CAS  Google Scholar 

  • Falliers C (1974) Familial coincidence of asthma, aspirin intolerance and nasal polyposis. Ann Allergy 32:65–69

    PubMed  CAS  Google Scholar 

  • Farr RS (1971) The capacity of aspirin to acetylate proteins in vitro and in vivo. In: Aldridge WN (ed) Mechanisms of toxicity. St. Martin, New York

    Google Scholar 

  • Ferreira SH, Moncada S, Vane JR (1971) Indomethacin and aspirin abolish prostaglandin release from the spleen. Nature New Biol 231:237–239

    PubMed  CAS  Google Scholar 

  • Fisherman EW, Cohen GN (1974) Alpha-beta adrenergic imbalance in intrinsic-intolerance rhinitis or asthma. Ann Allergy 33:86–101

    PubMed  CAS  Google Scholar 

  • Flandrin G, Daniel MT, Briere J, Varet B, Pestel M, Bernard J (1971) L’agranulocytose au pyramidon, une aplasie bréve de trois lignés. Nouv Rev Fr Hematol 11:219–221

    PubMed  CAS  Google Scholar 

  • Flower RJ (1974) Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev 26:33–67

    PubMed  CAS  Google Scholar 

  • Flower RJ, Blackwell GJ (1979) Anti-inflammatory steroids induce the biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation. Nature 278:456–459

    PubMed  CAS  Google Scholar 

  • Garg S, Sarker CR (1974) Aspirin-induced thrombocytopenia on an immune basis. Am J Med Sci 267:129–131

    PubMed  CAS  Google Scholar 

  • Gerber JG, Payne NA, Oelz O, Nies AS, Oates JA (1979) Tartrazine and the prostaglandin system. J Allergy Clin Immunol 63:289–294

    PubMed  CAS  Google Scholar 

  • Giraldo B, Blumenthal MN, Spink WW (1969) Aspirin intolerance and asthma. Ann Intern Med 71:479–485

    PubMed  CAS  Google Scholar 

  • Goldberg M, Murray TG (1978) Analgesic-associated nephropathy. N Engl J Med 299:716–717

    PubMed  CAS  Google Scholar 

  • Gross R, Hellriegel KP (1976) Arzneimittelbedingte Agranulozytosen. Blut 32:409–414

    PubMed  CAS  Google Scholar 

  • Gryglewski RJ (1976) Steroid hormones, anti-inflammatory steroids and prostaglandins. Pharmacol Res Commun 8:337–351

    PubMed  CAS  Google Scholar 

  • Gryglewski RJ (1979) Screening and assessment of potency of anti-inflammatory drugs in vitro. In: Vane JR, Ferreira SH (eds) Anti-inflammatory drugs. Handbook of experimental pharmacology, Springer-Verlag, Berlin Heidelberg New York, vol 50/2, pp 1–43

    Google Scholar 

  • Gryglewski RJ, Szczeklik A (1978) Inhibition of prostaglandin formation by lipid peroxides in the arterial wall: hypothetical step in development of atherosclerosis. Mater Med Pol 37:338–341

    Google Scholar 

  • Gryglewski RJ, Panczenko B, Korbut R, GrodziÅ„ska L, Ocetkiewicz A (1975 a) Corticosteroids inhibit prostaglandin release from perfused lungs of sensitized guinea pigs. Prostaglandins 10:343–355

    PubMed  CAS  Google Scholar 

  • Gryglewski RJ, Szczeklik A, Czerniawska-Mysik G (1975b) Aspirin sensitivity: other drugs. Ann Intern Med 83

    Google Scholar 

  • Gryglewski, RJ, DembiÅ„ska-Kieć, A, GrodziÅ„ska L, Panczenko B (1976) Differential generation of substances with prostaglandin-like and thromboxane-like activities by guinea pig trachea and lung strips. In: Bouhuys A (ed) Lung cells in disease. North Holland, Amsterdam Oxford New York, pp 289–307

    Google Scholar 

  • Gryglewski RJ, Szczeklik A, Niżankowska E (1977) Aspirin-sensitive asthma: its relationship to inhibition of prostaglandin biosynthesis. NATO Adv Study Inst Ser A Life Sci 13:191–203

    Google Scholar 

  • Gwin E, Kerby GR, Ruth WE (1977) Cromolyn sodium in the treatment of asthma associated with aspirin hypersensitivity and nasal polyps. Chest 72:148–154

    PubMed  CAS  Google Scholar 

  • Harnett JC, Spector SL, Farr RS (1978) Aspirin idiosyncrasy. In: Middleton E Jr, Reed CE, Ellis EF (eds) Allergy. Principles and practice. Mosby, St. Louis, pp 1002–1022

    Google Scholar 

  • Hennemann HH, Schief A (1975) Rezidive von Agranulozytose. Dtsch Med Wochenschr 100:519–522

    PubMed  CAS  Google Scholar 

  • Hume M, Eddy V (1977) Treatment of chronic airways obstruction with indomethacin. Scan J Respir Dis 58:284–286

    CAS  Google Scholar 

  • Irey NS (1976) Adverse drug reactions and death. JAMA 236:575–578

    PubMed  CAS  Google Scholar 

  • Jacob HS, Jandl JH (1962) Effects of sulfhydrol inhibition on red blood cells. J Clin Invest 41:779–790

    PubMed  CAS  Google Scholar 

  • Jeannet M, Lew D, Legendre C (1979) Amidopyrine pancytopenia: detection of leuco-cytotoxic antibodies by a 51Cr-release test. Acta Haematol (Basel) 61:52–54

    CAS  Google Scholar 

  • Juhlin L, Michaëlsson G, Zetterström O (1972) Urticaria and asthma induced by food-and-drug additives in patients with aspirin hypersensitivity. J Allergy Clin Immunol 50:92–98

    PubMed  CAS  Google Scholar 

  • Kaplan AP (1978) Urticaria and angioedema. In: Middleton E Jr, Reed CE, Ellis EF (eds) Allergy. Principles and practice. Mosby, St. Louis, pp 1080–1099

    Google Scholar 

  • Karpatkin S (1971) Drug-induced thrombocytopenia. Am J Clin Sci 262:69–78

    Google Scholar 

  • Kaufman HS (1977) Nasal polyps, syncope and asthma. Lancet 1:758

    PubMed  CAS  Google Scholar 

  • Kincaid-Smith P (1978) Analgesic nephropathy. Kidney Int 13:1–113

    PubMed  CAS  Google Scholar 

  • Klatskin G (1974) Drug-induced hepatic injury. In: Schaffner F, Sherlock S, Leevy CM (eds) The liver and its diseases. Intercontinental Medical Books, New York, pp 163–178

    Google Scholar 

  • Kordansky D, Adkinson F, Norman PS, Rosenthal RR (1978) Asthma improved by non-steroidal anti-inflammatory drugs. Ann Intern Med 88:508–511

    PubMed  CAS  Google Scholar 

  • Leist ER, Banwell JG (1974) Products containing aspirin. N Engl J Med 291:710–713

    PubMed  CAS  Google Scholar 

  • Lockey RF, Rucknagel DL, Vaneslow NA (1973) Familial occurrence of asthma and nasal polyps and aspirin intolerance. Ann Intern Med 78:57–63

    PubMed  CAS  Google Scholar 

  • Lockey SD (1977) Hypersensitivity to tartrazine (FD C Yellow No. 5) and other dyes and additives present in foods and pharmaceutical products. Ann Allergy 38:206–210

    PubMed  Google Scholar 

  • Maddsey WC, Boitnott JK (1977) Drug-induced chronic liver disease. Gastroenterology 72:1348–1353

    Google Scholar 

  • Mandell B, Shen HS, Hepburn B (1976) Fever from ibuprofen in a patient with lupus erythematosus. Ann Intern Med 85–209–210

    PubMed  CAS  Google Scholar 

  • Martelli NA, Usandivaras G (1977) Inhibition of aspirin-induced bronchoconstriction by sodium cromoglycate inhalation. Thorax 32:684–690

    PubMed  CAS  Google Scholar 

  • Matthews JI, Stage D (1974) Indomethacin, aspirin and urticaria. Ann Intern Med 80:771

    PubMed  CAS  Google Scholar 

  • Matthews KP, Lowell RG, Sheldon JM (1950) The problem of aspirin allergy with a report on skin testing with salicylate containing human sera J Lab Clin Med 36:416–419

    Google Scholar 

  • McDonald JR, Mathison DA, Stevenson DD (1972) Aspirin intolerance in asthma. J Allergy Clin Immunol 50:198–207

    PubMed  CAS  Google Scholar 

  • Michaëlsson G (1969) Chronic urticaria. Acta Derm venereol (Stockh) 49:404–416

    Google Scholar 

  • Mihatsch MJ, Zollinger HU, Torhorst J (1979) Pathognomonic lesion of analgesic nephropathy. E Engl J Med 300:1275–1276

    CAS  Google Scholar 

  • Miller RL, Insel PA, Melmon KL (1978) Inflammatory disorders. In: Melmon KL, Morelli WF (eds) Clinical pharmacology, 2nd edn. Macmillan, New York, pp 657–708

    Google Scholar 

  • Moeschlin S (1954) Weitere Beobachtungen über Immunleukopenien und Agranulozytosen. Schweiz Med Wochenschr 84:1100–1103

    PubMed  CAS  Google Scholar 

  • Moeschlin S, Wagner K (1952) Agranulocytosis due to the occurrence of leukocyte agglutinins (pyramidon and cold agglutinins). Acta Haematol (Basel) 8:29–41

    CAS  Google Scholar 

  • Molaney JR (1977) Nasal polyps, nasal polypectomy, asthma and aspirin sensitivity. J Laryngol Otol 91:837–846

    Google Scholar 

  • Moore-Robinson M, Warin RP (1967) Effect of salicytaes in urticaria. Br Med J 4:262–266

    PubMed  CAS  Google Scholar 

  • Nieweg HO, Bouma HGD, Vries KD (1963) Hematological side effects of some antirheumatic drugs. Ann Rheum Dis 22: 440–443

    PubMed  CAS  Google Scholar 

  • Nizankowska E, Szczeklik A (1979) Keine Bedenken gegen Solosin bei Acetylsalicylsäure-empfindlichen Asthmatikern. Dtsch Med Wochenschr 104:1388–1389

    PubMed  CAS  Google Scholar 

  • Noid HE, Schulze TW, Winkelmann RK (1974) Diet plan for patients with salicylate-in-duced urticaria. Arch Dermatol 109:666–670

    Google Scholar 

  • O’Brien JR (1968) Effects of salicylates on human platelets. Lancet 1:779–781

    PubMed  Google Scholar 

  • Okazaki T, Ilea VS, Rosario NA, Reisman RE, Arbesman CE, Lee JB, Middleton E Jr (1977) Regulatory role of prostaglandin E in allergic histamine release with observations on responsiveness of basophil leukocytes and the effect of acetylsalicylic acid. J Allergy Clin Immunol 60:360–366

    PubMed  CAS  Google Scholar 

  • Orehek J, Douglas JS, Bouhuys A (1975) Contractile responses of the guinea pig trachea in vitro: modification by prostaglandin synthesis-inhibiting drugs. J Pharmacol Exp Ther 194:554–564

    PubMed  CAS  Google Scholar 

  • Panczenko B, Grodzinska L, Gryglewski RJ (1975) The dual action of meclofenamate or contractive response to PGF2 in the guinea pig trachea. Pol J Phamacol Pharm 27:273–278

    CAS  Google Scholar 

  • Pasargiklian M, Bianco S, Allegra L, Moavero NE, Petrigni C, Robuschi M, Grugni A (1977) Aspects of bronchial reactivity to prostaglandins and aspirin in asthmatic patients. Respiration 34:79–91

    Google Scholar 

  • Patrono C, Ciabattoni G, Venuti A, Pugliese F, Schiavino D, Patriarca G (1978) Aspirin intolerance: unaltered susceptibility of platelet cyclo-oxygenase to inhibition by aspirin in vitro. J Allergy Clin Immunol 62:271–275

    PubMed  CAS  Google Scholar 

  • Prescott LF, Newton RW, Swainson CP, Wright N, Forrest ARW, Matthew H (1974) Successfull treatment of severe paracetamol overdosage with cysteamine. Lancet 1:588–592

    PubMed  CAS  Google Scholar 

  • Quick AJ (1966) Salicylates and bleeding. The aspirin tolerance test. Am J Med Sci 252:268–270

    Google Scholar 

  • Rachelefsky GS, Carlson A, Siegel CS, Stiehm ER (1975) Aspirin intolerance in chronic childhood asthma detected by oral challenge. Pediatrics 56:443–450

    PubMed  CAS  Google Scholar 

  • Rosenhall L (1977) Hypersensitivity to analgesics, preservatives and food colorants in patients with asthma or rhinitis. Acta Univ 269:1–117

    Google Scholar 

  • Rosenoer VM, Tornay AS (1979) Drugs and the liver. Med Clin North Am 63:405–412

    PubMed  CAS  Google Scholar 

  • Roth GJ, Stanford N, Majerus PW (1975) Acetylation of prostaglandin synthetase by aspirin. Proc Natl Acad Sci USA 72:3073–3078

    PubMed  CAS  Google Scholar 

  • Rudzki E (1977) Chronic urticaria due to aspirin and food additives (In Polish). Przegl Dermatol 64:163–166

    PubMed  CAS  Google Scholar 

  • Samter M (1973) Intolerance to aspirin. Hosp Pract 8:85–90

    Google Scholar 

  • Samter M, Beers RJ Jr (1968) Intolerance to aspirin: clinical studies and consideration of its pathogenesis. Ann Intern Med 68:975–983

    PubMed  CAS  Google Scholar 

  • Samuelsson B (1979) Oxygenation and further transformation of polyunsaturated fatty acids. Plenary Lecture at the IVth International Prostaglandin Conference, Washington, DC, May 1979

    Google Scholar 

  • Schlumberger HD, Löbbecke EA, Kallos P (1974) Acetylsalicylic acid intolerance. Acta Med Scand 196:451–458

    PubMed  CAS  Google Scholar 

  • Schuhl JF, Pereyra JG (1979) Oral acetylsalicylic acid (aspirin) in asthmatic children. Clin Allergy 9:83–88

    PubMed  CAS  Google Scholar 

  • Seaman WE, Ishak KG, Plotz PH (1974) Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus. Ann Intern Med 80:1–8

    PubMed  CAS  Google Scholar 

  • Serwonska M (1979) Non-acidic nonsteroidal anti-inflammatory drugs and aspirin-induced asthma (In Polish). PhD thesis, University of Cracow

    Google Scholar 

  • Settipane GA, Chafee FH, Klein DE (1974) Aspirin intolerance. II. A prospective study in atopic and normal population. J Allergy Clin Immunol 53:200–204

    PubMed  CAS  Google Scholar 

  • Settipane GA, Chafee FH, Postman IM et al. (1976) Significance of tartrazine sensitivity in chronic urticaria of unknown etiology. J Allergy Clin Immunol 57:541–546

    PubMed  CAS  Google Scholar 

  • Shen TY (1979) Prostaglandin synthetase inhibitors. In: Vane JR, Ferreira S (eds) Anti-inflammatory drugs. Springer, Berlin Heidelberg New York (Handbook of experimental pharmacology, vol 50/2, pp 305–347)

    Google Scholar 

  • Siegel MI, McConnel RT, Cuatrecasas P (1979) Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway. Proc Natl Acad Sci USA 76:3774–3778

    PubMed  CAS  Google Scholar 

  • Slapke J, Jäger L (1979) Untersuchungen zum Analgetika-Asthma. Gesellschaft Inn Med DDR 34:78–80

    CAS  Google Scholar 

  • Smith JB, Willis AL (1971) Aspirin selectively inhibits prostaglandin production in human platlets. Nature New Biol 231:235–237

    PubMed  CAS  Google Scholar 

  • Smith LJ, Slavin RG (1976) Drugs containing tartrazine dye. J Allergy Clin Immunol 58:456–470

    PubMed  CAS  Google Scholar 

  • Sonnenblick M, Abraham AS (1978) Ibuprofen hypersensitivity in systemic lupus erythematosus. Br Med J 1:618–619

    Google Scholar 

  • Spühler O, Zollinger HU (1953) Die chronisch-interstitielle Nephritis. Z Klin Med 151:1–50

    PubMed  Google Scholar 

  • Starr WR (1971) Familial aspirin hypersensitivity. Ann Allergy 29:498

    PubMed  CAS  Google Scholar 

  • Stenius BSM, Lemola M (1976) Hypersensitivity to acetylsalicylic acid (ASA) and tartrazine in patients with asthma. Clin Allergy 6:119–129

    PubMed  CAS  Google Scholar 

  • Stevenson DD, Arroyave CM, Bhat KN, Tan EM (1976) Oral aspirin challenge in asthmatic patients: a study of plasma histamine. Clin Allergy 6:493–506

    PubMed  CAS  Google Scholar 

  • Szczeklik A (1980) Analgesics, allergy and asthma. Br J Clin Pharacol 10:401–405

    Google Scholar 

  • Szczeklik A, Czerniawska-Mysik G (1976) Prostaglandins and aspirin-induced asthma. Lancet 1:488

    Google Scholar 

  • Szczeklik A, Serwonska M (1979) Inhibition by clemastine of adverse reactions to aspirin in patients with asthma and aspirin idiosyncrasy. Thorax 34:654–657

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G (1974) Is aspirin-sensitive asthma due to inhibition of prostaglandin synthesis? In: Proceedings of the Ninth European Congress of Allergy and Clinical Immunology, London, 1974, p 34

    Google Scholar 

  • Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G (1975 a) Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. Br Med J 1:67–69

    PubMed  CAS  Google Scholar 

  • Szczeklik, A, Musial J, Serwonska M (1975 b) The effect of aspirin on bleeding time and platelet aggregation in patients hypersensitivity to nonsteroidal anti-inflammatory drugs. Abstracts of the XIth Congress of the Polish Society of Haematologists. Gdansk, p64

    Google Scholar 

  • Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G, Zmuda A (1976) Aspirin-induced asthma. Hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action to prostaglandin generation by different microsomal enzymic preparations. J Allergy Clin Immunol 58:10–18

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G (1977 a) Clinical patterns of hypersensitivity to nonsteroidal anti-inflammatory drugs and their pathogenesis. J Allergy Clin Immunol 60:276–284

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G, Pieton R (1977 b) Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naproxen. Br Med J 2:231–232

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Olszewski E, Dembinska-Kiec A, Czerniawska-Mysik G (1977 c) Aspirin-sensitive asthma: the effect of aspirin on the release of prostaglandins from nasal polyps. Pharmacol Res Commun 9:415–425

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Nizankowska E, Nizankowski R (1977d) Bronchial reactivity to prostaglandin F2, E2, and histamine in different types of asthma, Respiration 34:323–331

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Nizankowska E (1978 a) Asthma relieved by aspirin and by other cyclo-oxygenase inhibitors. Thorax 33:664–665

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Nizankowska E, Nizankowski R, Musia I (1978b) Pulmonary and anti-platelet effects of intravenous and inhaled prostacyclin in man. Prostaglandins 16:651–660

    CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Nizankowska E (1979 a) Asthma improved by nonsteroidal anti-inflammatory drugs. Ann Intern Med 90:126–127

    PubMed  CAS  Google Scholar 

  • Szczeklik A, Gryglewski RJ, Grodzinska L, Musia J, Serwonska M, Marcinkiewicz E (1979b) Platelet aggregability, thromboxane A2 and malonaldehyde formation following administration of aspirin to man. Throm Res 15:405–413

    CAS  Google Scholar 

  • Szczeklik A, Czerniawska-Mysik G, Serwonska M, Kuklinski P (1980) Inhibition by ketotifen of idiosyncratic reactions to aspirin. Allergy 35:421–424

    PubMed  CAS  Google Scholar 

  • Trautlein J, Mann WJ (1978) Anaphylactic shock caused by yellow dye in an enema (case report). Ann Allergy 41:28–29

    PubMed  CAS  Google Scholar 

  • Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action of aspirin-like drugs. Nature New Biol 231:232–235

    PubMed  CAS  Google Scholar 

  • Vane JR (1976) The mode of action of aspirin and similar compounds. J Allergy Clin Immunol 58:691–712

    PubMed  CAS  Google Scholar 

  • Van Leeuwen WS (1928) Pathognomonische Bedeutung der Ãœberempfindlichkeit gegen Aspirin bei Asthmatikern. MMW 75:1588–1592

    Google Scholar 

  • Vedenthan PK, Menon MM, Bell TB, Bergin D (1977) Aspirin and tartrazine oral challenge: Incidence of adverse response in chronic childhood asthma. J Allergy Clin Immunol 60:8–13

    Google Scholar 

  • Virchow C (1976) Analgetika-Intoleranz bei Asthmatikern (Analgetika-Asthma-Syndrom). Prax Klin Pneumol 30:684–692

    CAS  Google Scholar 

  • Von Maur K, Adkinson NF, Van Metre TE, Marsh DG, Norman PS (1974) Aspirin intolerance in a family. J Allergy Clin Immunol 54:380–395

    Google Scholar 

  • Warin RP (1960) The effect of aspirin in chronic urticaria. Br J Dermatol 72:350–351

    PubMed  CAS  Google Scholar 

  • Warin RP, Smith RJ (1976) Challenge test battery in chronic urticaria. Br J Dermatol 94:401–406

    PubMed  CAS  Google Scholar 

  • Whittle BJR (1977) Prostaglandins and mast cell histamine release. NATO Adv Study Inst Ser Life Sci:345–351

    Google Scholar 

  • Woodbury DM, Fingl E (1979) Analgesic-antipyretics, anti-inflammatory agents, and drugs employed in the therapy of gout. In: Goodman LS, Gillman A (eds) The pharmacological basis of therapeutics, 5th edn. Macmillan, New York, pp 325–358

    Google Scholar 

  • Wuethrich B (1979) Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics. Respiration 37:224–227

    Google Scholar 

  • Yurchak WM, Wicher K, Arbesman CE (1970) Immunologi studies on aspirin. J Allergy 46:245–252

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. A. Szczeklik
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut für klinische Immunologie, Inselspital, CH-3010, Bern, Switzerland

    Alain L. de Weck

  2. Department of Pharmaceutical Chemistry AD, The Royal Danish School of Pharmacy, 2, Universitetsparken, DK-2100, Copenhagen, Denmark

    Hans Bundgaard

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Szczeklik, A. (1983). Analgesics and Nonsteroidal Anti-Inflammatory Drugs. In: de Weck, A.L., Bundgaard, H. (eds) Allergic Reactions to Drugs. Handbook of Experimental Pharmacology, vol 63. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69088-4_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69088-4_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69090-7

  • Online ISBN: 978-3-642-69088-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation