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The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration

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Book cover Fluid Dynamics as a Localizing Factor for Atherosclerosis

Abstract

More than a century after Rokitanski’s [14] incrustation hypothesis. of atherogenesis, good evidence has accumulated that white, platelet rich thrombi are not only involved in the complication of atherosclerosis [6] but also in its genesis. Ross’s detection of a smooth muscle cell proliferation stimulating factor, released from platelets stresses the paramount role of platelets in the development of the disease [15].

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Authors
  1. L. J. Wurzinger
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  2. R. Opitz
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  3. E. Blasberg
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  4. H. Eschweiler
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  5. H. Schmid-Schönbein
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Editor information

Editors and Affiliations

  1. Medizinische Klinik (Ludolf-Krehl-Klinik) der Universität, Bergheimer Straße 58, D-6900, Heidelberg 1, Germany

    Gotthard Schettler , Hubert Mörl  & Curt Diehm ,  & 

  2. Department of Mechanical Engineering, University of Houston, 77004, Houston, TX, USA

    Robert M. Nerem

  3. Abteilung Physiologie, Medizinische Fakultät der Rheinisch-Westfälischen Technischen Hochschule, Schneebergweg 211, D-5100, Aachen, Germany

    Holger Schmid-Schönbein

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© 1983 Springer-Verlag Berlin Heidelberg

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Wurzinger, L.J., Opitz, R., Blasberg, E., Eschweiler, H., Schmid-Schönbein, H. (1983). The Role of Hydrodynamic Factors in Platelet Activation and Thrombotic Events: The Effects of Shear Stress of Short Duration. In: Schettler, G., Nerem, R.M., Schmid-Schönbein, H., Mörl, H., Diehm, C. (eds) Fluid Dynamics as a Localizing Factor for Atherosclerosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69085-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-69085-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69087-7

  • Online ISBN: 978-3-642-69085-3

  • eBook Packages: Springer Book Archive

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