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Glucagon II pp 99–114Cite as

Hormones in the Control of Glucagon Secretion

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 66 / 2))

Abstract

This is a review of the knowledge on one of the messenger systems involved in the regulation of secretion of glucagon. The messengers in this system are hormones, and, by definition, they are blood borne and reach their target, namely the A-cells of pancreatic islets, through the vascular system. The purpose of this hormonal messenger system is multiple. (1) The availability of hormones that are involved in the regulation of certain metabolic events would be coordinated by each influencing the secretion of the other (Sects. B-E). (2) Hormones which are secreted by cells in the intestinal endothelium could alert the glucagon-producing cell to the approaching work load, namely the assimilation of ingested nutrients (Sect. F). (3) High level coordination of metabolic events would be achieved by the central nervous system via the humoral route (Sects. G, H).

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Authors
  1. S. B. Pek
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  2. R. S. Spangler
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Editors and Affiliations

  1. University of Liège, Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

  2. University of Brussels (V.U.B.), Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

  3. Royal Academy of Medicine of Belgium, Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

  4. Medical Policlinics, University of Liège, Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

  5. Division of Diabetes, University of Liège, Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

  6. Institut de Médecine, Hôpital de Bavière, Boulevard de la Constitution, 66, 4020, Liège, Belgium

    Pierre J. Lefebvre M.D. (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head) (Professor of Medicine, Guest Professor, Corresponding Member, Chairman, Head)

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© 1983 Springer-Verlag Berlin Heidelberg

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Pek, S.B., Spangler, R.S. (1983). Hormones in the Control of Glucagon Secretion. In: Lefebvre, P.J. (eds) Glucagon II. Handbook of Experimental Pharmacology, vol 66 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69019-8_7

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  • DOI: https://doi.org/10.1007/978-3-642-69019-8_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69021-1

  • Online ISBN: 978-3-642-69019-8

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