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Age-Related Changes in the Anterior Segment of the Eye

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Book cover Geriatrics 3

Abstract

In general, the tissues of the anterior segment of the eye undergo the same aging processes which take place in the organism as a whole. However, the special role of the eye as a device for optical function has led to the development of specialized mechanisms which, in some places, may also inhibit or even prevent common aging processes. This inhibition of age-related degeneration in certain constituents of the connective tissue may prevent early dysfunction in this important sensory organ. Such dysfunction may be more critical on the survival of the organism than comparable aging processes in the skin or bones; e.g., the maintenance of corneal transparency and a constant intraocular pressure are of fundamental biologic importance. The corneal transparency depends on a continuous process of dehydration and a certain degree of “nonaging” of the connective tissue found in the corneal stroma (cf. Sect. B. I). With respect to intraocular pressure maintenance, it appears that the age-related increase in outflow resistance is counteracted by a simultaneous decrease in aqueous formation. This may be the means by which the tissues of the ciliary body and the chamber angle maintain a fairly constant intraocular pressure during life. Similar interrelated processes may also develop at other sites of the eye (Fig. 1). Thus, aging in the eye cannot be considered an isolated, uniformly developing degenerative process. Rather, it is a complicated process of structural and biologic changes of interrelated functional systems whereby systems may compensate for changes occurring in a neighboring system and vice versa. We are far from a real pathologic or gerontologic understanding of such interrelations and functional mechanisms.

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References

  • Alvarado J, Murphy C, Polansky J, Juster R (1981) Age-related changes in the trabecular meshwork cellularity. Invest Ophthalmol Vis Sci 21:714–727

    PubMed  CAS  Google Scholar 

  • Bairati A, Grignolo A (1954) Preliminary investigations of the submicroscopic structure of Descemet’s membrane with the electron microscope. Boll Soc Ital Biol Sper 30:16

    PubMed  CAS  Google Scholar 

  • Bairati A, Orzalesi N (1966) The ultrastructure of the epithelium of the ciliary body. A study of the function complexes and of the changes associated with the production of plasmoid aqueous humor. Z Zellforsch Mikrosk Anat 69:635–658

    Article  PubMed  Google Scholar 

  • Bashey RI, Kern HL (1972) Studies of collagen of bovine cornea. Ophthalmic Res 4:246–256

    Article  Google Scholar 

  • Bigar F (1982) Specular microscopy of corneal endothelium Dev Ophthalmol 6:1–94

    PubMed  CAS  Google Scholar 

  • Bill A, Svedbergh B (1972) Scanning electron microscopic studies of the trabecular meshwork and the canal of Schlemm. An attempt to localize the mean resistance to outflow of aqueous humor in man. Acta Ophthalmol 50:295–320

    CAS  Google Scholar 

  • Blatt HL, Rao GN, Aquavella JV (1979) Endothelial density in relation to morphology. Invest Ophthalmol Vis Sci 18:856

    PubMed  CAS  Google Scholar 

  • Bornfeld N, Spitznas M, Breipohl W, Bijvank GJ (1974) Scanning electron microscopy of the zonule of Zinn. I. Human Eyes. Albert von Graefes Arch Klin Ophthalmol 192:117–129

    Article  CAS  Google Scholar 

  • Bourne W, Kaufman HE (1976) Specular microscopy of human comeal endothelium in vivo. Am J Ophthalmol 81:319

    PubMed  CAS  Google Scholar 

  • Brini A (1957) Le reseau trabeculaire de l’angle de la chambre anterieure. Etude histologique et histochimique. Ann Ocul (Paris) 190:755–777

    CAS  Google Scholar 

  • Bryson JM, Wolter JR, O’Keefe NT (1966) Ganglion cells in the human ciliary body. Arch Ophthalmol 75:57

    PubMed  CAS  Google Scholar 

  • Burke PA, Farnsworth P (1980) Development of the human fetal lens. Invest Ophthalm Vis Sci (Suppl, ARVO, Orlando) p 116

    Google Scholar 

  • Calmettes L, Deodati F, Flanel H, Bec P (1956) Etude histologique et histochemique de l’epithélium anterieur de la cornée et de ses basalés. Arch Ophthalmol (Paris) 16:481

    Google Scholar 

  • Cogan DG, Kuwabara T (1959) Arcus senilis. Its pathology and histochemistry. Arch Ophthalmol 61:553

    CAS  Google Scholar 

  • Dardenne MU, Iwangoff P, Diotallevi M (1968) Unterschiede im Verhalten des Kollagens der einzelnen Hornhautschichten mit zunehmendem Lebensalter. Ophthalmologica 156:385–393

    Article  PubMed  CAS  Google Scholar 

  • Donaldson DD (1974) Transillumination of the iris. Trans Am Ophthalmol Soc 72:89

    PubMed  CAS  Google Scholar 

  • Enke P, Rohen JW (1983) Morphological studies on the regeneration of rabbit corneal endothelium under influence of corticosteroids. Albrecht von Grafes Arch Klin Exp Ophthalmol 220:19–24

    CAS  Google Scholar 

  • Feeney ML, Garron LK (1961) Descemet’s membrane in the human peripheral cornea. A study by light and electron microscopy. In: Smelser GK (ed) The structure of the eye. Academic, New York

    Google Scholar 

  • Fine BS, Zimmerman LE (1963) Light an e.m. observations on the ciliary epithelium in man and rhesus monkey. Invest Ophthalmol 2:105

    Google Scholar 

  • Gärtner J (1965) Elektronenmikroskopische Untersuchungen über Glaskörperrindenzellen und Zonulafasern. Z Zellforsch 66:737–764

    Article  PubMed  Google Scholar 

  • Gärtner J (1970) Electron microscopic observations on the cilio-zonular border of the human eye with particular reference to the ageing changes. Z Anat Entwicklungsgesch 131:263–273

    Article  PubMed  Google Scholar 

  • Graumann W, Rohen JW (1958) Chemohistologische Befunde am menschlichen Auge (Cornea, Sclera, Uvea). Z Mikrosk Anat Forsch 64:652–671

    CAS  Google Scholar 

  • Greiling H, Driesch R, Momburg M, Jagdfeld R, Thomas J, Stuhlsatz HW (1976) Zur Alternsabhängigkeit der Glycosyltransferasen. In: Platt D (ed) Alternstheorien, 3rd Gießener Symposium. Schattauer, Stuttgart, pp 205–217

    Google Scholar 

  • Grierson I, Lee WR (1973) Erythrocyte phagocytosis in the human trabecular meshwork. Br J Ophthalmol 57:400–415

    Article  PubMed  CAS  Google Scholar 

  • Grierson I, Lee WR (1978) Further observations on the process of haemophagocytosis in the human outflow system. Albrecht Von Grafes Arch Klin Ophthalmol 208:49–64

    Article  CAS  Google Scholar 

  • Grierson I, Robins, E, Howes RC (1980) Preliminary observations in the human trabecular meshwork cells in vitro. Albrecht Von Graefes Arch Klin Ophthalmol 212:173–186

    Article  CAS  Google Scholar 

  • Grierson I, Wang Q, McMenamin PG, Lee WR (1982) The effects of age and antiglaucoma drugs on the meshwork cell population. New Perspectives in Ophthalmology. Research and Clinical Forums vol 4, no 5, pp 69–92

    Google Scholar 

  • Hahn H, Timm G (1976) Untersuchungen zur physiol. Hämosiderosen des Auges. Folia ophthalmol 4:249

    Google Scholar 

  • Hanna C, Bicknell DS, O’Brien JE (1961) Cell turnover in the adult human eye. Arch Ophthalmol 65:695

    PubMed  CAS  Google Scholar 

  • Hara K, Lütjen-Drecoll E, Prestele H, Rohen JW (1977) Structural differences between regions of the ciliary body in primates. Invest Ophthalmol Vis Sci 16:912–924

    PubMed  CAS  Google Scholar 

  • Hogan MJ, Alvarado JA, Weddell J (1971) Histology of the human eye. An atlas and textbook. Saunders Philadelphia

    Google Scholar 

  • Horstmann HJ, Rohen JW, Sames K (1983) Age changes of proteins in the human trabecular meshwork. Mech Ageing Dev 21:121–136

    Article  PubMed  CAS  Google Scholar 

  • Ishikawa T (1962) Fine structure of the human ciliary muscle. Invest Ophthalmol Vis Sci 1:587–608

    CAS  Google Scholar 

  • Jaeger W, Eisenhauer GG (1977) Der diagnostische Wert der Arcus corneae als Hinweis auf Lipoidstoffwechselstörungen. Klin Monatsbl Augenheilkd 171:321

    PubMed  CAS  Google Scholar 

  • Jakus MA (1956) Studies on the cornea. II. The fine structure of Descemet’s membrane. J Biophys Biochem Cytol (Suppl) 2:241

    Article  Google Scholar 

  • Jakus MA (1961) The fine structure of the human cornea. In: Smelser GK (ed) The Structure of the eye. Academic New York

    Google Scholar 

  • Kaufman HE, Capella MS, Robbins JE (1966) The human comeal endothelium. Am J Ophthalmol 61:835

    PubMed  CAS  Google Scholar 

  • Kaufman PL, Rohen JW, Bârâny EH (1979) Hyperopia and loss of accommodation following ciliary muscle disinsertion in the cynomolgus monkey. Invest Ophthalmol Vis Sci 18:665–673

    PubMed  CAS  Google Scholar 

  • Kaye GI, Pappas GD (1962) Studies on the cornea. I. The fine structure of the rabbit cornea and the uptake and transport of colloidal particles by the cornea in vivo. J Cell Biol 21–457

    Google Scholar 

  • Kayes, J, Holmberg A (1960) The fine structure of Bowman’s layer and the basement membrane of the corneal epithelium. Am J Ophthalmol 50–1013

    Google Scholar 

  • Laties AM (1972) Specific neurohistology comes of age: A look back and a look forward. Invest Ophthalmol Vis Sci 11:553

    Google Scholar 

  • Laule A, Cable MK, Hoffman CE, Hanna C (1978) Endothelial cell population changes of human cornea during life. Arch Ophthalmol 96:2031

    PubMed  CAS  Google Scholar 

  • Lee WR, Grierson I, McMenamin PG (1982) The morphological response of the primate outflow system to changes in pressure and flow. In: Lütjen-Drecoll E (ed) Basic aspects of glaucoma research. Schattauer, Stuttgart, pp 123–140

    Google Scholar 

  • Leeson TH, Speakman JS (1961) The fine structure of extracellular material in the pectinate ligament (trabecular meshwork) of the human iris. Acta Anat 46:363–379

    Article  PubMed  CAS  Google Scholar 

  • Lütjen-Drecoll E (1973) Structural factors influencing outflow facility and its changeability under drugs, a study in macaca arctoides. Invest Ophthalmol Vis Sci 12:280–294

    Google Scholar 

  • Lütjen-Drecoll E (1982) Functional morphology of the ciliary epithelium. In: Lütjen-Drecoll E (ed) Basic aspects of Glaucoma research. Schattauer, Stuttgart, pp 69–88

    Google Scholar 

  • Lütjen-Drecoll E, Lönnerholm G (1981) Distribution of carbonic-anydrase in the rabbit eye. Invest Ophthalmol 21:782–797

    Google Scholar 

  • Lütjen-Drecoll E, Futa R, Rohen JW (1981) Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 21:563–573

    PubMed  Google Scholar 

  • Lütjen-Drecoll E, Dietl T, Futa R, Rohen JW (1982) Age changes of the trabecular meshwork: a preliminary morphometric study. In: Hollyfield JG (ed) Structure of the eye, IV. Symposium. Elsevier North Nolland, Amsterdam, pp 341–348

    Google Scholar 

  • Lütjen-Drecoll E, Lönnerholm G, Eichhorn M (1983) Carbonic anhydrase in the human and monkey eye by light and electron microscopy. Albrecht von Graefes. Arch Klin Ophthalmol 220:285–291

    Google Scholar 

  • McMenamin PG, Lee WR (1980) Age-related changes in extracellular materials in the inner wall of Schlemm’s canal. Albrecht von Graefes Arch Klin Exp Ophthalmol 212:159–172

    Article  PubMed  CAS  Google Scholar 

  • Naumann GOH (1980) Pathologie des Auges. In: Doerr W, Seifert G, Uehlinger E (eds) Spezielle pathologische Anatomie, vol 12. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Norn MS (1971) Iris pigment defects in normals. Acta Opthalmol (Copenh) 49:887

    Article  CAS  Google Scholar 

  • Ober MJ, Rohen JW (1979) Regional differences in the fine structure of the ciliary epithelium related to accommodation. Invest Ophthalmol Vis Sci 18:655–664

    PubMed  CAS  Google Scholar 

  • Okamura R, Lütjen-Drecoll E (1973) Elektronenmikroskopische Untersuchungen über die Altersveränderungen der menschlichen Iris. Albrecht von Graefes Arch Klin Ophthalmol 186:249–269

    Article  CAS  Google Scholar 

  • Okisaka S, Kuwabara T, Rapoport SI (1976) Effect of hyperosomotic agents on the ciliary epithelium and trabecular meshwork. Invest Ophthalmol Vis Sci 15:617–625

    CAS  Google Scholar 

  • Okun E (1960) Pathology in autopsy eyes. Am J Ophthalmol 50:424–429 (part I), 574–583 (part II)

    PubMed  CAS  Google Scholar 

  • Raviola G (1977) The structural basis of the blood-ocular barriers. Exp Eye Res (Suppl) 25:27–63

    Article  PubMed  Google Scholar 

  • Raviola G, Raviola E (1978) Intercellular junctions in the ciliary epithelium. Invest Ophthalmol Vis Sci 17/10:959–981

    Google Scholar 

  • Reddy VN (1982) Biochemistry of aqueous humor. In: Lütjen-Drecoll E (ed) Basic aspects of Glaucoma research. Schattauer, Stuttgart, pp 89–112

    Google Scholar 

  • Rentsch FJ, Van Der Zypen E (1971) Altersbedingte Veränderungen der sog. Membrana limitans int. des Ziliarkörpers im menschl. Auge. In: Bredt H, Rohen JW (eds) Ageing and development, vol 1. Schattauer, Stuttgart, pp 70–94

    Google Scholar 

  • Rodgrigues MM, Spaeth GL, Livalingham E, Weinreb S (1976) Histopathology of 150 trabeculectomy specimens in glaucoma. Trans Ophthalmol Soc UK 96:245–255

    Google Scholar 

  • Rohen H (1951) Der Bau der Regenbogenhaut beim Menschen und einigen Säugetieren. Gegenbaurs Morphol Jahrb 91:140–181

    Google Scholar 

  • Rohen JW (1952) Der Ziliarkörper als funktionelles System Gegenbaurs Morphol Jahrb 92:415–440

    Google Scholar 

  • Rohen JW (1962) Über das Lig. pectinatum der Primaten. Z Zellforsch 58:403–421

    Article  PubMed  CAS  Google Scholar 

  • Rohen JW (1964) Das Auge und seine Hilfsorgane. In: Möllendorff W, Bargmann W (eds) Haut und Sinnesorgane. Handbuch der mikroskopischen Anatomie des Menschen, vol 3/4. Springer, Berlin Göttingen Heidelberg New York, pp 348–354

    Google Scholar 

  • Rohen JW (1979) Scanning electron microscopic studies of zonular apparatus in human and monkey eyes. Invest Ophthalmol Vis Sci 18:133

    PubMed  CAS  Google Scholar 

  • Rohen JW (1982) The evolution of the primate Eye in relation to the problem of glaucoma. In: Lütjen-Drecoll E (ed) Basic aspects of glaucoma research. Schattauer, Stuttgart, pp 3–33

    Google Scholar 

  • Rohen JW (1983) Why is i.o. pressure elevated in chronic simple glaucoma? Anatomical considerations. XXIV. Int Congr Ophthalmol, San Francisco, American Academy Ophthalmology 90:758–765

    CAS  Google Scholar 

  • Rohen JW, Lütjen-Drecoll E (1968) Über die Altersveränderungen des Trabekelwerkes im menschlichen Auge. Albrecht von Graefes Arch Klin Ophthalmol 175:285–307

    Article  CAS  Google Scholar 

  • Rohen JW, Lütjen-Drecoll E (1971) Age changes of the trabecular meshwork in human and monkey eyes. In: Bredt H, Rohen JW (eds) Ageing and development, vol I. Schattauer, Stuttgart pp 1–36

    Google Scholar 

  • Rohen JW, Lütjen-Drecoll E (1981) Ageing and non-ageing processes within the connective tissues of the anterior segment of the eye. In: Müller WEG, Rohen JW (eds) Biochemical and morphological aspects of ageing. Abhandlung Akademie der Wissenschaften und Literatur, Mainz. Steiner, Wiesbaden, pp 157–174

    Google Scholar 

  • Rohen JW, Lütjen-Drecoll E (1982) Biology of the trabecular meshwork. In: Lütjen-Drecoll E (ed) Basic aspects of Glaucoma research. Schattauer, Stuttgart

    Google Scholar 

  • Rohen JW, Shimizu TS (to be published) Fine structure of ciliary muscle tips and outer wall of Schlemm’s canal in normal and glaucomatous eyes. Albrecht von Graefes Arch Klin Ophthalmol

    Google Scholar 

  • Rohen JW, Unger HH (1959) Zur Morphologie und Pathologie der Kammerbucht des Auges. In: Abh Mainzer Akad Wiss Lit Math Naturwiss, Kl 3. Steiner, Wiesbaden, pp 1–206

    Google Scholar 

  • Rohen JW, Van der Zypen E (1968) The phagocytic activity of the trabecular meshwork endothelium. An electron microscopy study of the vervet (cercopithecus aethiops). Albrecht Von Graefes Arch Klin Ophthalmol 175:143–160

    Article  CAS  Google Scholar 

  • Rohen JW, Voth D (1960) Zur Irisstruktur der Primaten. Ophthalmologica 140:27–33

    Article  PubMed  CAS  Google Scholar 

  • Rohen JW, Witmer R (1972) Electron microscopic studies on the trabecular meshwork in glaucoma simplex. Albrecht Von Graefes Arch Klin Ophthalmol 183:251–266

    Article  CAS  Google Scholar 

  • Rohen JW, Zimmermann A (1970) Altersveränderungen des Ciliarepithels beim Menschen. Albrecht Von Graefes Arch Klinik Ophthalmol 179:302–317

    Article  CAS  Google Scholar 

  • Rohen JW, Futa R, Lütjen-Drecoll E (1981) The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections. Invest Ophthalmol Vis Sci 21:574–585

    PubMed  CAS  Google Scholar 

  • Sames K (1979) Histochemical demonstration of acidic glycosaminoglycans in the cell nuclei of the iris and other tissues. Acta Anat 103:74–82

    Article  PubMed  CAS  Google Scholar 

  • Sames K, Rohen JW (1978) Histochemical studies on the Glycosaminoglycans in the normal and glaucomatous iris of human eyes. Albrecht Von Graefes Arch Klin Ophthalmol 207:157–167

    Article  CAS  Google Scholar 

  • Schachtschabel DO, Wever J, Rohen JW, Bigalke B (1981) Changes in glycosaminoglycans synthesis during in vitro ageing of cultured WI-38 cells and trabecular meshwork cells of the primate eye. In: Müller WEG, Rohen JW (eds) Biochemical and morphological aspects of ageing. Steiner, Wiesbaden, pp 175–185

    Google Scholar 

  • Schachtschabel DO, Rohen JW, Wever J, Sames K (1982) Synthesis and composition of GAGs by cultured human trabecular meshwork cells. Albrecht Von Graefes Arch Klin Ophthalmol 218:113–117

    CAS  Google Scholar 

  • Schwarz W (1953) Elektronenmikroskopische Untersuchungen über die Differenzierung der Cornea- und Sklerafibrillen des Menschen. Z Zellforsch 38:78–86

    Article  PubMed  CAS  Google Scholar 

  • Schwarz W (1972) Anatomie der Cornea. Ber Zusammenkunft Dtsch Ophthalmol Ges 69:12–18

    Google Scholar 

  • Schwarz W, Keyserlingk G (1969) Elektronenmikroskopische Untersuchungen an humanen Homhautnarben und an einem getrübten Hornhauttransplantat. Virchows Arch [Pathol Anat] 347:115–128

    Article  CAS  Google Scholar 

  • Schwarz W, Keyserlingk G, Graf D (1966) Über die Feinstruktur der menschlichen Cornea mit besonderer Berücksichtigung des Problems der Transparenz. Z Zellforsch 73:540–548

    Article  PubMed  CAS  Google Scholar 

  • Shiose Y (1970) Electron microscopic studies on blood retinal and blood aqueous barriers. J J Ophthalmol 14:73–87

    Google Scholar 

  • Smith RS, Rudt LA (1973) Ultrastructural studies of the blood aqueous barrier. 2. The barrier to horseradish peroxidase in primates. Am J Ophthalmol 76:937–947

    PubMed  CAS  Google Scholar 

  • Smith RS, Rudt LA (1975) Ocular vascular and epithelial barriers to microperoxidase. Invest Ophthalmol Vis Sci 14:556–560

    CAS  Google Scholar 

  • Stieve R (1949) Über den Bau des menschlichen Ziliarmuskels und seine Veränderungen während des Lebens... Anat Anz 97:69–79

    Google Scholar 

  • Z Mikrosk Anat Forschg 55:3–88

    Google Scholar 

  • Teng CC, Katzin HM (1953) The basement membrane of corneal epithelium. A perliminary report. Am J Ophthalmol 36:895

    PubMed  CAS  Google Scholar 

  • Van der Zypen E (1967) Licht- und elektronenmikroskopische Untersuchungen über den Bau und die Innervation des Ziliarmuskels bei Mensch und Affe (Cercopithecus aethiops). Albrecht Von Graefes Arch Klin Ophthalmol 174:143–168

    Article  Google Scholar 

  • Vander Zypen E (1970) Licht- und elektronenmikroskopische Untersuchungen über die Altersveränderungen am M. ciliaris im menschlichen Auge. Albrecht Von Graefes Arch Klin Exp Ophthalmol 179:332–357

    Article  PubMed  Google Scholar 

  • Van der Zypen E (1971) Vergleichende licht- und elektronenmikroskopische Untersuchungen über die morphologischen Grundlagen der Liquor- und Kammerwasserzirkulation. Habil.-schr. Altern und Entwicklung 3. Schattauer, Stuttgart

    Google Scholar 

  • Van der Zypen E, Rentsch FJ (1971) Altersbedingte Veränderungen am Ziliarkörper des menschlichen Auges. In: Bredt H, Rohen JW (eds) Ageing and development, vol 1. Schattauer, Stuttgart, pp 37–94

    Google Scholar 

  • Vegge T (1971) An epithelial blood-aqueous barrier to horseradish peroxidase in the processes of the newt monkey (Cercopithecus aethiops). Z Zellforsch Mikrosk Anat 114:309–320

    Article  PubMed  CAS  Google Scholar 

  • Viidik A (1979) Connective tissues - possible implications of the temporal changes for the ageing process. Mech Ageing Dev 9:267–285

    Article  PubMed  CAS  Google Scholar 

  • Wormer W, Sames K, Rohen JW (1979) Histochemische Untersuchungen über Struktur und Alternsveränderungen der Descemetschen Membran beim Ring. Albrecht Von Grafes Arch Klin Ophthalmol 211:271–278

    Article  CAS  Google Scholar 

  • Yamashita T, Becker B, Cibis PA (1960) Histochemical studies of the primate ciliary body. Am J Ophthalmol 50:407

    PubMed  CAS  Google Scholar 

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  1. J. W. Rohen
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  2. E. Lütjen-Drecoll
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  1. Direktor des Instituts für Gerontologie der Universität Erlangen-Nürnberg und der 2. Medizinischen Klinik Klinikum Nürnberg, Flurstraße 17, D-8500, Nürnberg, Germany

    Dieter Platt

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Rohen, J.W., Lütjen-Drecoll, E. (1984). Age-Related Changes in the Anterior Segment of the Eye. In: Platt, D. (eds) Geriatrics 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68976-5_13

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