Abstract
Patients with ventricular tachycardia run a substantial risk of sudden death; therefore, therapy to prevent such arrhythmias is critical. However, noninvasive tests such as continuous electrocardiographic recordings, exercise testing, or both, often provide data insufficient for determining antiarrhythmic drug efficacy. For example, occurrences of arrhythmia may be separated widely in time, and many patients who are given drugs that seem to be effective at the time of hospital discharge die suddenly or are readmitted because of recurrent arrhythmias and/or syncope. Further, antiarrhythmic drugs are also arrhythmogenic and can result in sudden death although the arrhythmogenicity of the drug may not be apparent for weeks or months (Rinkenberger et al. 1982; Selzer and Wray 1964; Meltzer et al. 1978).
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References
Denes P, Wu D, Dhingra RC, Amat-Y-Leon F, Wyndham C, Mautner RK, Rosen KM, (1976) Electrophysiologic studies in patients with chronic recurrent ventricular tachycardia. Circulation 54: 229–236
Fisher JD, Cohen HL, Mehra R, Altschuler H, Escher DJW, Furman S, (1977) Cardiac pacing and pacemakers. II. Serial electrophysiologic-pharmacologic testing for control of recurrent tachyarrhythmias. Am Heart J 93: 658–668
Greene HL, Reid PR, Schaeffer AH, (1978) The repetitive ventricular response in man. A predictor of sudden death. N Engl J Med 299: 729–734
Horowitz LN, Josephson ME, Farshidi A, Spielman SR, Michelson EL, Greenspan AM, (1978) Recurrent sustained ventricular tachycardia. 3. Role of the electrophysiologic study in selection of antiarrhythmic regimens. Circulation 58: 986–997
Josephson ME, Horowitz LN, Farshidi A, Kastor JA, (1978) Recurrent sustained ventricular tachycardia. 1. Mechanisms. Circulation 57: 431–440
Mason JW, Winkle RA, (1978) Electrode-catheter arrhythmia induction in the selection and assessment of antiarrhythmic drug therapy for recurrent ventricular tachycardia. Circulation 58: 971–985
Meltzer RS, Robert EW, McMorrow M, Martin RP, (1978) Atypical ventricular tachycardia as a manifestation of disopyramide toxicity. Am J Cardiol 42: 1049–1053
Naccarelli GV, Prystowsky EN, Jackman WM, Heger JJ, Rinkenberger RL, Zipes DP, (1981) The repetitive ventricular response. Prevalence and prognostic significance. Br Heart J 46: 152–158
Naccarelli GV, Prystowsky EN, Jackman WM, Heger JJ, Rahilly GT, Zipes DP, (1982) Role of electrophysiologic testing in managing patients who have ventricular tachycardia unrelated to coronary artery disease. Am J Cardiol 50: 165–171
Parkinson J, Papp C, (1947) Repetitive paroxysmal tachycardia. Br Heart J 9: 241–262
Prystowsky EN, Heger JJ, Zipes DP, (1982) The recognition and treatment of patients at risk for sudden Death. In: Eliot RS (ed) Cardiac emergencies. Futura, Mount Kisco/New York, 353–384
Rahilly GT, Prystowsky EN, Zipes DP, Naccarelli GV, Jackman WM, Heger JJ, (1982) Clinical and electrophysiologic findings in patients with repetitive monomorphic ventriculartachycardia and otherwise normal electrocardiogram. Am J Cardiol 50: 459–468
Rinkenberger RL, Prystowsky EN, Jackman WM, Naccarelli GV, Heger JJ, Zipes DP, (1982) Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: Identification of drugs that exacerbate tachycardia and potential mechanisms. Am Heart J 103: 117–184
Ruskin JN, DiMarco JP, Garan H, (1980) Out-of-hospital cardiac arrest: electrophysiologic observations and selection of long-term antiarrhythmic drug therapy. N Engl J Med 303: 607–613
Schaeffer AH, Greene HL, Reid PR, (1978) Suppression of the repetitive ventricular response: an index of long-term antiarrhythmic effectiveness of aprindine for ventricular tachycardia in man. Am J Cardiol 42: 1007–1012
Selzer A, Wray HW, (1964) Quinidine syncope. Paroxysmal ventricular fibrillation occurring during treatment of chronic atrial arrhythmias. Circulation 30: 17–26
Vandepol CJ, Farshidi A, Spielman SR, Greenspan AM, Horowitz LN, Josephson ME, (1980) Incidence and clinical significance of induced ventricular tachycardia. Am J Cardiol 45: 725–731
Wellens HJJ, Duren DR, Lie KI, (1976) Observations on mechanisms of ventricular tachycardia in man. Circulation 54: 237–244
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Prystowsky, E.N., Naccarelli, G.V., Heger, J.J., Zipes, D.P. (1983). Electrophysiologic Testing in Patients with Ventricular Tachycardia. In: Schlepper, M., Olsson, B. (eds) Cardiac Arrhythmias. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68926-0_7
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DOI: https://doi.org/10.1007/978-3-642-68926-0_7
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