Propafenone, Flecainide and Mexiletine in the Treatment of Stable Ventricular Premature Beats

  • H.-W. Klempt
  • A. Nayebagha


The antiarrhythmic effects of oral doses of propafenone (P), flecainide (F), and mexiletine (M) were compared with one another in 12 patients with coronary heart disease and ventricular premature beats (VPBs) requiring treatment.


Placebo Fatigue Depression Propa Constipation 


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  1. Bethge K-P, Lichtlen PR (1981) Die Beurteilung der antiarrhythmischen Therapie durch Langzeit-elektrokardiographie. In: Luederitz B (ed) Ventrikulaere Herzrhythmusstörungen. Springer, Berlin Heidelberg New York p 170Google Scholar
  2. Seipel L, Breithardt G (1978) Electrophysiological effects of mexiletine in man: Influence on stimulus-induced ventricular arrhythmias. In: Sandøe E, Julian DG, Bell JW (eds) Management of ventricular tachycardia — role of mexiletine. Excerpta Medica, Amsterdam p 219Google Scholar

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© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • H.-W. Klempt
  • A. Nayebagha

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