Zusammenfassung
Der Dünndarm stellt ein Organsystem dar, das am wenigsten zu Neubildungen neigt. Obwohl seine Länge 75–80% des gesamten Intestinaltrakts ausmacht, finden sich nur 0,5–6% aller intestinalen Tumoren in seinem Bereich (Groenni- Geru. Georgi 1977). Benigne Tumoren führen bei fehlender Größenentwicklung zu keinen nennenswerten Symptomen und werden bei Obstruktion oder intestinaler Blutung zufällig entdeckt (Cohen et al. 1971). Malignóme des Dünndarms sind in Operationsstatistiken häufiger anzutreffen als benigne Tumoren; dabei stehen an erster Stelle die Karzinome (Geroulanos U. Hahnloser 1975). Von allen Malignomen des Magen-Darm-Trakts sind 40% im Magen oder Kolon lokalisiert, aber nur 0,5–0,7% im Dünndarm. Lowenfels (1973) sieht in dem flüssigen Darminhalt und der raschen Passagezeit mit nur kurzem Mukosakon- takt möglicher Karzinogene einen wichtigen Faktor für die Seltenheit von Dünndarmmalignomen. Die Bildung von Immunglobulinen im Dünndarm mag zu der relativen „Immunität“zusätzlich beitragen (Lowenfels 1973). Das geringere Auftreten von Adenokarzinomen im Ileum und die größere Menge an lymphatischem Gewebe könnten in diese Richtung weisen (Bridge U. Perzin 1975).
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Rasenack, U. (1983). Tumoren des Dünndarms. In: Bommer, W., et al. Dünndarm B. Handbuch der inneren Medizin, vol 3 / 3 / B. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68897-3_7
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