Skip to main content

Ätiologische und epidemiologische Aspekte chronisch-entzündlicher Darmerkrankungen

  • Chapter
Dünndarm B

Part of the book series: Handbuch der inneren Medizin ((INNEREN 3,volume 3 / 3 / B))

  • 34 Accesses

Zusammenfassung

Mehrere Gründe sprechen dafür, die ätiologischen und epidemiologischen Aspekte von Colitis ulcerosa und M. Crohn gemeinsam zu betrachten. Einerseits sachliche, denn nicht immer können beide Krankheiten diagnostisch sauber voneinander unterschieden werden. Auch genetische Studien deuten auf gemeinsame Vererbungsmerkmale hin. Andererseits sind es pragmatische Gründe, denn Anfang der 70er Jahre wurde u.a. im nordamerikanischen Schrifttum keine Trennung zwischen M. Crohn und Colitis ulcerosa vorgenommen (möglicherweise auch um bei den doch recht selten vorkommenden Krankheiten zu größeren Zahlen zu kommen), so daß zahlreiche Ergebnisse der (immunologischen) Forschung nur unter dem gemeinsamen Aspekt der chronisch-entzündlichen Darmerkrankungen gewertet werden können.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Abraham R, Coulston F (1979) Ulcerative lesions due to carregeenan. Z Gastroenterol (Suppl) 17: 154–158

    CAS  Google Scholar 

  • Ahlberg J, Bergstrand O, Holmstrom B, Kronevi T, Reiland S (1978) Negative findings in search for a transmissible agent in Crohn’s disease. Acta Chir Scand (Suppl) 482: 45–47

    CAS  Google Scholar 

  • Almy TP, Sherlock P (1966) Genetic aspects of ulcerative colitis and regional enteritis. Gastroenterology 51: 757–760

    PubMed  CAS  Google Scholar 

  • Aluwihare APR (1971) Electron microscopy in Crohn’s disease. Gut 12: 509–518

    Article  PubMed  CAS  Google Scholar 

  • Anderson AFR (1942) Ulcerative colitis - an allergic phenomenon. Am J Dig Dis 9: 91–98

    Article  Google Scholar 

  • Aronson MD, Phillips CA, Beeken WL et al. (1975) Isolation and characterization of a viral agent from intestinal tissue of patients with Crohn’s disease and other intestinal disorders. Prog Med Virol 21: 165–176

    PubMed  CAS  Google Scholar 

  • Auer IA (1979) Immunology in Crohn’s disease. Z Gastroenterol (Suppl) 17: 83–93

    Google Scholar 

  • Beeken WL (1979) Evidence of virus infection as a cause of Crohn’s disease. Z Gastroenterol (Suppl) 17: 101–104

    Google Scholar 

  • Bergman L, Krause U (1975) The incidence of Crohn’s disease in Central Sweden. Scand J Gastroent 10: 725–729

    PubMed  CAS  Google Scholar 

  • Bergstrand O, Holmstrom B, Gustafsson BG (1978) Contamination of germfree animals with intestinal Crohn’s tissue: a preliminary report. Acta Chir Scand (Suppl) 482: 48–50

    CAS  Google Scholar 

  • Bolton PM, Owen E, Heatley RV, Jones Williams W, Hughes LE (1973) Negative findings in laboratory animals for a transmissible agent in Crohn’s disease. Lancet II: 1122–1123

    Google Scholar 

  • Bonnevie O, Riis P, Anthonisen P (1968) An epidemiological study of ulcerative colitis in Copenhagen country. Scand J Gastroenterol 3: 432–438

    CAS  Google Scholar 

  • Brahme F, Lindström C, Wenckert A (1975) Crohn’s disease in a defined population. An epidemiological study of incidence, prevalence, mortality, and secular trends in the city of Malmö, Sweden. Gastroenterology 69: 342–351

    PubMed  CAS  Google Scholar 

  • Brandtzaeg P, Baklien K (1979) Immunopathology of the intestinal lesion in Crohn’s disease. Z Gastroenterol (Suppl) 17: 77–82

    Google Scholar 

  • Breucha G, Riethmüller G (1975) Intestinal lymphocytes in Crohn’s disease. Lancet 1: 976

    Article  PubMed  CAS  Google Scholar 

  • Broberger O, Perlmann P (1959) Autoantibodies in human ulcerative colitis. J Exp Med 110: 657–674

    Article  PubMed  CAS  Google Scholar 

  • Broberger O, Perlmann P (1963) In vitro studies of ulcerative colitis. 1. Reactions of patients’ serum with human fetal colon cells in tissue culture. J Exp Med 117: 705–715

    Article  PubMed  CAS  Google Scholar 

  • Burnham WR, Lennard-Jones JE, Stanford JL, Bird RG (1978) Mycobacteria as a possible cause of inflammatory bowels disease. Lancet II: 693–696

    Google Scholar 

  • Carstensen J (1979) Food additives and their possible role in Crohn’s disease. Z Gastroenterol (Suppl) 17: 145–153

    Google Scholar 

  • Carstensen J, Poulsen E (1971) Food additives and food contaminants. In regional enteritis (Crohn’s disease). Engel, A., Larsson, T. (eds.). Skandia International Symposia. Nordiska Bokhandelns Forlag, Stockholm, pp 283–299

    Google Scholar 

  • Cave DR, Mitchell DN, Brooke BN (1975) Experimental animal studies of the etiology and pathogenesis of Crohn’s disease. Gastroenterology 69: 618–624

    PubMed  CAS  Google Scholar 

  • Cave DR, Mitchell DN, Kane SP, Brooke BN (1973) Further animal evidence of a transmissible agent in Crohn’s disease. Lancet 11: 1120–1122

    Article  Google Scholar 

  • Cave DR, Mitchell DN, Brooke BM (1978) Induction of granulomas in mice by Crohn’s disease tissue. Gastroenterology 75: 632–637

    PubMed  CAS  Google Scholar 

  • De Dombal FT (1971) Symposium on Crohn’s disease: epidemiology and natural history. Proc R Soc Med 64: 161

    PubMed  Google Scholar 

  • Engel GL (1955) Studies of ulcerative colitis. III. The nature of the psychological process. Am J Med 19: 231–256

    Article  PubMed  CAS  Google Scholar 

  • Evans JG, Acheson ED (1965) An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area. Gut 6: 311–324

    Article  PubMed  CAS  Google Scholar 

  • Fahrländer H, Baerlocher Ch (1971) Clinical features and epidemiological data on Crohn’s disease in the Basle area. Scand J Gastroenterol 6: 657–662

    Google Scholar 

  • Falchuk KR, Isselbacher KJ (1976) Circulating antibodies to bovine albumin in ulcerative colitis and Crohn’s disease. Gastroenterology 70: 5–8

    PubMed  CAS  Google Scholar 

  • Farmer GW, Vincent MM, Fucillo DA et al. (1973) Viral investigations in ulcerative colitis and regional enteritis. Gastroenterology 65: 8–15

    PubMed  CAS  Google Scholar 

  • Farmer RG, Michener WM, Mortimer EA (1980) Studies of family history among patients with inflammatory bowel disease. Clin Gastroenterol 9 /2: 271–278

    PubMed  CAS  Google Scholar 

  • Garagliano CF, Mendeloff AI, Lilienfeld AM. First hospitalization rates for ulcerative proctocolitis and Crohn’s disease in Baltimore 1963–1973, and for 16 other areas in 1973.

    Google Scholar 

  • Gilat T, Ribak J, Benaroya Y (1974) Ulcerative colitis in the Jewish population of Tel-Aviv Jafo. I. Epidemiology. Gastroenterology 66: 335–342

    PubMed  CAS  Google Scholar 

  • Gitnick GL, Rosen VJ (1976) Electron microscopic studies of viral agents in Crohn’s disease. Lancet 11: 217–219

    Article  Google Scholar 

  • Gitnick GL, Arthur MH, Shibata I (1976) Cultivation of viral agents from Crohn’s disease. A new sensitive system. Lancet 11: 215–217

    Article  Google Scholar 

  • Groen J, Bastiaans O (1955) Studies on ulcerative colitis: personality structure, emotional conflict, situations and effects of psychotherapy. In: Modern trends in psychosomatic medicine. O’Neill DF (ed), Butterworths, London, pp 242 ff. Heaton KW, Thornton JR, Emmet PM (1979) Dietary factors in Crohn’s disease. Z Gastroenterol (Suppl) 17: 140–144

    Google Scholar 

  • Hoj L, Jensen B, Bonnevie O, Riis P (1973) An epidemiological study of regional enteritis and acute ileitis in Copenhagen country. Scand J Gastroenterol 8:381–384 Humphreys WG (1975) An epidemiological survey of Crohn’s disease in Northern Ireland. Proc RSoc Med 68: 1975

    Google Scholar 

  • Jewell DP, Truelove SC (1972) Circulating antibodies to cow’s milk proteins in ulcerative colitis. Gut 13: 796–801

    Article  PubMed  CAS  Google Scholar 

  • Kasper H, Sommer H (1979) Dietary fiber and nutrient intake in Crohn’s disease. Am J Clin Nutr 32: 1898–1901

    PubMed  CAS  Google Scholar 

  • Keighley MRB, Arabi Y, Dimock F, Burdon DW, Allen RN, Alexander-Williams J (1978) Influence of inflammatory bowel disease on intestinal microflora. Gut 19: 1099–1104

    Article  PubMed  CAS  Google Scholar 

  • Kirsner JB, Spencer J A (1963) Familial occurrences of ulcerative colitis, regional enteritis and ileocolitis. Ann Intern Med 59: 133–144

    PubMed  CAS  Google Scholar 

  • Krause U, Bergmann L, Norlen BJ (1971) A clinical study based on 186 patients. Scand J Gastroenterol 6: 97–108

    Article  PubMed  CAS  Google Scholar 

  • Kyle J (1971) An epidemiological study of Crohn’s disease in Northeast Scotland. Gastroenterology 61: 826–833

    PubMed  CAS  Google Scholar 

  • Kyle J (1972) Crohn’s disease. Heinemann, London

    Google Scholar 

  • Lagercrantz R, Hammarstrom S, Perlmann P, Gustafsson BE (1968) Immunological studies in ulcerative colitis. III. Incidence of antibodies to colon-antigen in ulcerative colitis and other gastrointestinal diseases. Clin Exp Med 128: 1339–1352

    CAS  Google Scholar 

  • Latimer PR (1978) Crohn’s disease: a review of the psychological and social outcome. Psychol Med 8: 649–656

    Article  PubMed  CAS  Google Scholar 

  • Lewkonia RM, McConnell RB (1973) Familial inflammatory bowel disease - heredity or environment? Gut 17: 235–243

    Article  Google Scholar 

  • Lindemann E (1950) Modifications in the course of ulcerative colitis in relationship to changes in life situations and reaction patterns. Proc Assoc Res Nervous Mental Dis 29: 706–723

    Google Scholar 

  • Martini GA, Brandes JW (1976) Increased consumption of refined carbohydrates in patients with Crohn’s disease. Klin Wochenschr 54: 367–371

    Article  PubMed  CAS  Google Scholar 

  • Mayberry JF, Rhodes J, Newcombe RG (1980) Increased sugar consumption in Crohn’s disease. Digestion 20: 323–326

    Article  PubMed  CAS  Google Scholar 

  • McConnell RB (1979) Genetics in Crohn’s disease. Z Gastroenterol (Suppl) 17: 61–65

    Google Scholar 

  • Melnyk CS (1975) Experimental colitis. In: Kirsner JB, Shorter RG (eds) Inflammatory bowel disease. Lea and; Febiger, Philadelphia, pp 23–26

    Google Scholar 

  • Mendeloff AI (1979) Epidemiology of Crohn’s disease. Z Gastroenterol (Suppl) 17: 66–69

    Google Scholar 

  • Mendeloff AI (1980) The epidemiology of inflammatory bowel disease. Clin Gastroenterol 9 /2: 259–270

    PubMed  CAS  Google Scholar 

  • Miller B, Fervers F, Robbeck R, Strohmeyer G (1976) Zuckerkonsum bei Patienten mit Morbus Crohn. Verh Dtsch Ges Inn Med 82: 922–924

    PubMed  Google Scholar 

  • Miller DS, Keighley AC, Langmann MJS (1974) Changing pattterns in epidemiology of Crohn’s disease. Lancet 11: 691–693

    Article  Google Scholar 

  • Mitchell PD, Parent K (1979) Cell wall-defective pseudomonas-like bacteria: their possible significance in the etiology of Crohn’s disease. Z Gastroenterol (Suppl) 17: 109–112

    Google Scholar 

  • Mitchell DN, Rees RJ (1970) Agent transmissible from Crohn’s disease tissue. Lancet 11: 168–171

    Article  Google Scholar 

  • Mitchell DN, Rees RJ (1976) Further observations on the transmissibility of Crohn’s disease. Ann NY Acad Sci 278: 546–558

    Article  PubMed  CAS  Google Scholar 

  • Mitchell DN, Rees RJ (1979) Possible role of infectious agents in Crohn’s disease. Z Gastroenterol (Suppl) 17: 98–100

    Google Scholar 

  • Mitchell DN, Rees RJ, Goswami KK (1976) Transmissible agents from human sarcoid and Chron’s disease tissues. Lancet II: 761–765

    Google Scholar 

  • Monk M, Mendeloff AI, Siegel CI, Lilienfeld A (1967) An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. I. Hospital incidence and prevalence, 1960 to 1963. Gastroenterology 53: 198–210

    Google Scholar 

  • Murray CB (1930) Psychogenic factors in the etiology of ulcerative colitis and bloody diarrhea. Am J Med Sci 180: 239–248

    Article  Google Scholar 

  • Myren J, Gjone E, Hertzberg JN (1971) Epidemiology of ulcerative colitis and regional enterocolitis (Crohn’s disease) in Norway. Scand J Gastroenterol 6: 511–514

    CAS  Google Scholar 

  • Norlen BJ, Krause U, Bergmann L (1970) An epidemiological study of Crohn’s disease. Scand J Gastroenterol 5: 385–390

    PubMed  CAS  Google Scholar 

  • Parent K, Mitchell P (1978) Cell wall defective variants of pseudomonas-like (Group Va) bacteria in Crohn’s disease. Gastroenterology 75: 368–372

    PubMed  CAS  Google Scholar 

  • Riemann JF (1977) Further electron microscopic evidence of virus-like particles in Crohn’s disease. Acta Hepatogastroenterol 24: 116–118

    CAS  Google Scholar 

  • Roche JK, Huang ES (1977) Viral DNA in inflammatory bowel disease. CMV bearing cells as a target for immune mediated enterocytolysis. Gastroenterology 72: 228–233

    PubMed  CAS  Google Scholar 

  • Rozen P, Zonis J, Yekutiel P, Gilat T (1979) Crohn’s disease in the jewish population of Tel-Aviv-Yafo. Gastroenterology 76: 25–30

    PubMed  CAS  Google Scholar 

  • Sachar DB, Auslander MO, Walfish JS (1980) Aetiological theories of inflammatory bowel disease. Clin Gastroenterol 9 /2: 231–257

    PubMed  CAS  Google Scholar 

  • Schuller J, Piket-Van Ulsen LJ, Veeken IVD, Michel MF, Stolz E (1979) Antibodies against Chlamydia of lymphogranuloma venereum type in Crohn’s disease. Lancet 1: 19–20

    Article  PubMed  CAS  Google Scholar 

  • Sedlack RE, Nobrega FT, Kurland LT, Sauer WG (1972) Inflammatory colon disease in Rochester, Minnesota, 1935–1964. Gastroenterology 62: 935–941

    PubMed  CAS  Google Scholar 

  • Shorter RG, Chiba M, Thayer WR, Bartnik W, Remine SG (1979) Further studies of cell-mediated immunity in inflammatory bowel disease - a preliminary report. Z Gastroenterol (Suppl) 17: 72–76

    Google Scholar 

  • Stanford JL, White SA, Burnham WR, Lennard-Jones JE, Bird RG (1979) Mycobacteria and inflammatory bowel disease. Lancet 1: 444

    Article  PubMed  CAS  Google Scholar 

  • Strickland RG, Volpicelli NA, Robinson JM et al. (1979) Isolation of infectious agents from patients with inflammatory bowel disease (Abstr). Clin Res 27:29 A

    Google Scholar 

  • Tabaqchali S, O’Donoghue DP, Bettelheim KA (1978) Escherichia coli antibodies in patients with inflammatory bowel disease. Gut 19: 108–113

    Article  PubMed  CAS  Google Scholar 

  • Taub RN, Sachar DB, Siltzbach LE, Janowitz HD (1974) Transmission of ileitis and sarcoid granulomas to mice. Trans Assoc Am Physicians 87: 219–224

    PubMed  CAS  Google Scholar 

  • Taub RN, Sachar DB, Janowitz HD, Siltzbach LE (1976) Induction of granulomas in mice by inoculation of tissue homogenates from patients with inflammatory bowel disease and sarcoidosis. Ann NY Acad Sci 278: 560–564

    Article  PubMed  CAS  Google Scholar 

  • Taylor KB, Truelove SC (1961) Circulating antibodies to milk proteins in ulcerative colitis. Br Med J 11: 924–929

    Article  Google Scholar 

  • Tresadern JC, Gear MWL, Nicol A (1973) An epidemiological study of regional enteritis in the Gloucester area. Br J Surg 60: 366–368

    Article  PubMed  CAS  Google Scholar 

  • Ward M (1977) The pathogenesis of Crohn’s disease. Lancet 11: 903 - 905

    Article  Google Scholar 

  • Ward M (1979) Phagocytic function in Crohn’s disease. Z Gastroenterol (Suppl) 17: 116–124

    Google Scholar 

  • Weinstock HI (1962) Successful treatment of ulcerative colitis by psychoanalysis: a survey of 28 cases with follow-up. J Psychosom Dis 6: 243–249

    Article  CAS  Google Scholar 

  • White SA, Nassau E, Burnham WR, Stanford JL, Lennard-Jones JE (1978) Further evidence for a mycobacterial aetiology of Crohn’s disease. Gut 19: A 443–444

    Google Scholar 

  • Whorwell PJ, Phillips CA, Beeken WL (1977) Isolation of reovirus-like agents from patients with Crohn’s disease. Lancet 1: 1169–1171

    Article  PubMed  CAS  Google Scholar 

  • Wigley RD, MacLaurin BP (1962) A study of ulcerative colitis in New Zealand, showing a low incidence in Maoris. Br Med J 11: 228–231

    Article  Google Scholar 

  • Wright R, Truelove SC (1966a) Autoimmune reactions in ulcerative colitis. Gut 7: 32–40

    Article  PubMed  CAS  Google Scholar 

  • Wright R, Truelove SC (1966b) Serial rectal biopsy in ulcerative colitis during the course of a controlled therapeutic trial of various diets. Am J Dig Dis 11: 847–857

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Malchow, H. (1983). Ätiologische und epidemiologische Aspekte chronisch-entzündlicher Darmerkrankungen. In: Bommer, W., et al. Dünndarm B. Handbuch der inneren Medizin, vol 3 / 3 / B. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68897-3_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-68897-3_30

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68898-0

  • Online ISBN: 978-3-642-68897-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics