Zusammenfassung
Mehrere Gründe sprechen dafür, die ätiologischen und epidemiologischen Aspekte von Colitis ulcerosa und M. Crohn gemeinsam zu betrachten. Einerseits sachliche, denn nicht immer können beide Krankheiten diagnostisch sauber voneinander unterschieden werden. Auch genetische Studien deuten auf gemeinsame Vererbungsmerkmale hin. Andererseits sind es pragmatische Gründe, denn Anfang der 70er Jahre wurde u.a. im nordamerikanischen Schrifttum keine Trennung zwischen M. Crohn und Colitis ulcerosa vorgenommen (möglicherweise auch um bei den doch recht selten vorkommenden Krankheiten zu größeren Zahlen zu kommen), so daß zahlreiche Ergebnisse der (immunologischen) Forschung nur unter dem gemeinsamen Aspekt der chronisch-entzündlichen Darmerkrankungen gewertet werden können.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Abraham R, Coulston F (1979) Ulcerative lesions due to carregeenan. Z Gastroenterol (Suppl) 17: 154–158
Ahlberg J, Bergstrand O, Holmstrom B, Kronevi T, Reiland S (1978) Negative findings in search for a transmissible agent in Crohn’s disease. Acta Chir Scand (Suppl) 482: 45–47
Almy TP, Sherlock P (1966) Genetic aspects of ulcerative colitis and regional enteritis. Gastroenterology 51: 757–760
Aluwihare APR (1971) Electron microscopy in Crohn’s disease. Gut 12: 509–518
Anderson AFR (1942) Ulcerative colitis - an allergic phenomenon. Am J Dig Dis 9: 91–98
Aronson MD, Phillips CA, Beeken WL et al. (1975) Isolation and characterization of a viral agent from intestinal tissue of patients with Crohn’s disease and other intestinal disorders. Prog Med Virol 21: 165–176
Auer IA (1979) Immunology in Crohn’s disease. Z Gastroenterol (Suppl) 17: 83–93
Beeken WL (1979) Evidence of virus infection as a cause of Crohn’s disease. Z Gastroenterol (Suppl) 17: 101–104
Bergman L, Krause U (1975) The incidence of Crohn’s disease in Central Sweden. Scand J Gastroent 10: 725–729
Bergstrand O, Holmstrom B, Gustafsson BG (1978) Contamination of germfree animals with intestinal Crohn’s tissue: a preliminary report. Acta Chir Scand (Suppl) 482: 48–50
Bolton PM, Owen E, Heatley RV, Jones Williams W, Hughes LE (1973) Negative findings in laboratory animals for a transmissible agent in Crohn’s disease. Lancet II: 1122–1123
Bonnevie O, Riis P, Anthonisen P (1968) An epidemiological study of ulcerative colitis in Copenhagen country. Scand J Gastroenterol 3: 432–438
Brahme F, Lindström C, Wenckert A (1975) Crohn’s disease in a defined population. An epidemiological study of incidence, prevalence, mortality, and secular trends in the city of Malmö, Sweden. Gastroenterology 69: 342–351
Brandtzaeg P, Baklien K (1979) Immunopathology of the intestinal lesion in Crohn’s disease. Z Gastroenterol (Suppl) 17: 77–82
Breucha G, Riethmüller G (1975) Intestinal lymphocytes in Crohn’s disease. Lancet 1: 976
Broberger O, Perlmann P (1959) Autoantibodies in human ulcerative colitis. J Exp Med 110: 657–674
Broberger O, Perlmann P (1963) In vitro studies of ulcerative colitis. 1. Reactions of patients’ serum with human fetal colon cells in tissue culture. J Exp Med 117: 705–715
Burnham WR, Lennard-Jones JE, Stanford JL, Bird RG (1978) Mycobacteria as a possible cause of inflammatory bowels disease. Lancet II: 693–696
Carstensen J (1979) Food additives and their possible role in Crohn’s disease. Z Gastroenterol (Suppl) 17: 145–153
Carstensen J, Poulsen E (1971) Food additives and food contaminants. In regional enteritis (Crohn’s disease). Engel, A., Larsson, T. (eds.). Skandia International Symposia. Nordiska Bokhandelns Forlag, Stockholm, pp 283–299
Cave DR, Mitchell DN, Brooke BN (1975) Experimental animal studies of the etiology and pathogenesis of Crohn’s disease. Gastroenterology 69: 618–624
Cave DR, Mitchell DN, Kane SP, Brooke BN (1973) Further animal evidence of a transmissible agent in Crohn’s disease. Lancet 11: 1120–1122
Cave DR, Mitchell DN, Brooke BM (1978) Induction of granulomas in mice by Crohn’s disease tissue. Gastroenterology 75: 632–637
De Dombal FT (1971) Symposium on Crohn’s disease: epidemiology and natural history. Proc R Soc Med 64: 161
Engel GL (1955) Studies of ulcerative colitis. III. The nature of the psychological process. Am J Med 19: 231–256
Evans JG, Acheson ED (1965) An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area. Gut 6: 311–324
Fahrländer H, Baerlocher Ch (1971) Clinical features and epidemiological data on Crohn’s disease in the Basle area. Scand J Gastroenterol 6: 657–662
Falchuk KR, Isselbacher KJ (1976) Circulating antibodies to bovine albumin in ulcerative colitis and Crohn’s disease. Gastroenterology 70: 5–8
Farmer GW, Vincent MM, Fucillo DA et al. (1973) Viral investigations in ulcerative colitis and regional enteritis. Gastroenterology 65: 8–15
Farmer RG, Michener WM, Mortimer EA (1980) Studies of family history among patients with inflammatory bowel disease. Clin Gastroenterol 9 /2: 271–278
Garagliano CF, Mendeloff AI, Lilienfeld AM. First hospitalization rates for ulcerative proctocolitis and Crohn’s disease in Baltimore 1963–1973, and for 16 other areas in 1973.
Gilat T, Ribak J, Benaroya Y (1974) Ulcerative colitis in the Jewish population of Tel-Aviv Jafo. I. Epidemiology. Gastroenterology 66: 335–342
Gitnick GL, Rosen VJ (1976) Electron microscopic studies of viral agents in Crohn’s disease. Lancet 11: 217–219
Gitnick GL, Arthur MH, Shibata I (1976) Cultivation of viral agents from Crohn’s disease. A new sensitive system. Lancet 11: 215–217
Groen J, Bastiaans O (1955) Studies on ulcerative colitis: personality structure, emotional conflict, situations and effects of psychotherapy. In: Modern trends in psychosomatic medicine. O’Neill DF (ed), Butterworths, London, pp 242 ff. Heaton KW, Thornton JR, Emmet PM (1979) Dietary factors in Crohn’s disease. Z Gastroenterol (Suppl) 17: 140–144
Hoj L, Jensen B, Bonnevie O, Riis P (1973) An epidemiological study of regional enteritis and acute ileitis in Copenhagen country. Scand J Gastroenterol 8:381–384 Humphreys WG (1975) An epidemiological survey of Crohn’s disease in Northern Ireland. Proc RSoc Med 68: 1975
Jewell DP, Truelove SC (1972) Circulating antibodies to cow’s milk proteins in ulcerative colitis. Gut 13: 796–801
Kasper H, Sommer H (1979) Dietary fiber and nutrient intake in Crohn’s disease. Am J Clin Nutr 32: 1898–1901
Keighley MRB, Arabi Y, Dimock F, Burdon DW, Allen RN, Alexander-Williams J (1978) Influence of inflammatory bowel disease on intestinal microflora. Gut 19: 1099–1104
Kirsner JB, Spencer J A (1963) Familial occurrences of ulcerative colitis, regional enteritis and ileocolitis. Ann Intern Med 59: 133–144
Krause U, Bergmann L, Norlen BJ (1971) A clinical study based on 186 patients. Scand J Gastroenterol 6: 97–108
Kyle J (1971) An epidemiological study of Crohn’s disease in Northeast Scotland. Gastroenterology 61: 826–833
Kyle J (1972) Crohn’s disease. Heinemann, London
Lagercrantz R, Hammarstrom S, Perlmann P, Gustafsson BE (1968) Immunological studies in ulcerative colitis. III. Incidence of antibodies to colon-antigen in ulcerative colitis and other gastrointestinal diseases. Clin Exp Med 128: 1339–1352
Latimer PR (1978) Crohn’s disease: a review of the psychological and social outcome. Psychol Med 8: 649–656
Lewkonia RM, McConnell RB (1973) Familial inflammatory bowel disease - heredity or environment? Gut 17: 235–243
Lindemann E (1950) Modifications in the course of ulcerative colitis in relationship to changes in life situations and reaction patterns. Proc Assoc Res Nervous Mental Dis 29: 706–723
Martini GA, Brandes JW (1976) Increased consumption of refined carbohydrates in patients with Crohn’s disease. Klin Wochenschr 54: 367–371
Mayberry JF, Rhodes J, Newcombe RG (1980) Increased sugar consumption in Crohn’s disease. Digestion 20: 323–326
McConnell RB (1979) Genetics in Crohn’s disease. Z Gastroenterol (Suppl) 17: 61–65
Melnyk CS (1975) Experimental colitis. In: Kirsner JB, Shorter RG (eds) Inflammatory bowel disease. Lea and; Febiger, Philadelphia, pp 23–26
Mendeloff AI (1979) Epidemiology of Crohn’s disease. Z Gastroenterol (Suppl) 17: 66–69
Mendeloff AI (1980) The epidemiology of inflammatory bowel disease. Clin Gastroenterol 9 /2: 259–270
Miller B, Fervers F, Robbeck R, Strohmeyer G (1976) Zuckerkonsum bei Patienten mit Morbus Crohn. Verh Dtsch Ges Inn Med 82: 922–924
Miller DS, Keighley AC, Langmann MJS (1974) Changing pattterns in epidemiology of Crohn’s disease. Lancet 11: 691–693
Mitchell PD, Parent K (1979) Cell wall-defective pseudomonas-like bacteria: their possible significance in the etiology of Crohn’s disease. Z Gastroenterol (Suppl) 17: 109–112
Mitchell DN, Rees RJ (1970) Agent transmissible from Crohn’s disease tissue. Lancet 11: 168–171
Mitchell DN, Rees RJ (1976) Further observations on the transmissibility of Crohn’s disease. Ann NY Acad Sci 278: 546–558
Mitchell DN, Rees RJ (1979) Possible role of infectious agents in Crohn’s disease. Z Gastroenterol (Suppl) 17: 98–100
Mitchell DN, Rees RJ, Goswami KK (1976) Transmissible agents from human sarcoid and Chron’s disease tissues. Lancet II: 761–765
Monk M, Mendeloff AI, Siegel CI, Lilienfeld A (1967) An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. I. Hospital incidence and prevalence, 1960 to 1963. Gastroenterology 53: 198–210
Murray CB (1930) Psychogenic factors in the etiology of ulcerative colitis and bloody diarrhea. Am J Med Sci 180: 239–248
Myren J, Gjone E, Hertzberg JN (1971) Epidemiology of ulcerative colitis and regional enterocolitis (Crohn’s disease) in Norway. Scand J Gastroenterol 6: 511–514
Norlen BJ, Krause U, Bergmann L (1970) An epidemiological study of Crohn’s disease. Scand J Gastroenterol 5: 385–390
Parent K, Mitchell P (1978) Cell wall defective variants of pseudomonas-like (Group Va) bacteria in Crohn’s disease. Gastroenterology 75: 368–372
Riemann JF (1977) Further electron microscopic evidence of virus-like particles in Crohn’s disease. Acta Hepatogastroenterol 24: 116–118
Roche JK, Huang ES (1977) Viral DNA in inflammatory bowel disease. CMV bearing cells as a target for immune mediated enterocytolysis. Gastroenterology 72: 228–233
Rozen P, Zonis J, Yekutiel P, Gilat T (1979) Crohn’s disease in the jewish population of Tel-Aviv-Yafo. Gastroenterology 76: 25–30
Sachar DB, Auslander MO, Walfish JS (1980) Aetiological theories of inflammatory bowel disease. Clin Gastroenterol 9 /2: 231–257
Schuller J, Piket-Van Ulsen LJ, Veeken IVD, Michel MF, Stolz E (1979) Antibodies against Chlamydia of lymphogranuloma venereum type in Crohn’s disease. Lancet 1: 19–20
Sedlack RE, Nobrega FT, Kurland LT, Sauer WG (1972) Inflammatory colon disease in Rochester, Minnesota, 1935–1964. Gastroenterology 62: 935–941
Shorter RG, Chiba M, Thayer WR, Bartnik W, Remine SG (1979) Further studies of cell-mediated immunity in inflammatory bowel disease - a preliminary report. Z Gastroenterol (Suppl) 17: 72–76
Stanford JL, White SA, Burnham WR, Lennard-Jones JE, Bird RG (1979) Mycobacteria and inflammatory bowel disease. Lancet 1: 444
Strickland RG, Volpicelli NA, Robinson JM et al. (1979) Isolation of infectious agents from patients with inflammatory bowel disease (Abstr). Clin Res 27:29 A
Tabaqchali S, O’Donoghue DP, Bettelheim KA (1978) Escherichia coli antibodies in patients with inflammatory bowel disease. Gut 19: 108–113
Taub RN, Sachar DB, Siltzbach LE, Janowitz HD (1974) Transmission of ileitis and sarcoid granulomas to mice. Trans Assoc Am Physicians 87: 219–224
Taub RN, Sachar DB, Janowitz HD, Siltzbach LE (1976) Induction of granulomas in mice by inoculation of tissue homogenates from patients with inflammatory bowel disease and sarcoidosis. Ann NY Acad Sci 278: 560–564
Taylor KB, Truelove SC (1961) Circulating antibodies to milk proteins in ulcerative colitis. Br Med J 11: 924–929
Tresadern JC, Gear MWL, Nicol A (1973) An epidemiological study of regional enteritis in the Gloucester area. Br J Surg 60: 366–368
Ward M (1977) The pathogenesis of Crohn’s disease. Lancet 11: 903 - 905
Ward M (1979) Phagocytic function in Crohn’s disease. Z Gastroenterol (Suppl) 17: 116–124
Weinstock HI (1962) Successful treatment of ulcerative colitis by psychoanalysis: a survey of 28 cases with follow-up. J Psychosom Dis 6: 243–249
White SA, Nassau E, Burnham WR, Stanford JL, Lennard-Jones JE (1978) Further evidence for a mycobacterial aetiology of Crohn’s disease. Gut 19: A 443–444
Whorwell PJ, Phillips CA, Beeken WL (1977) Isolation of reovirus-like agents from patients with Crohn’s disease. Lancet 1: 1169–1171
Wigley RD, MacLaurin BP (1962) A study of ulcerative colitis in New Zealand, showing a low incidence in Maoris. Br Med J 11: 228–231
Wright R, Truelove SC (1966a) Autoimmune reactions in ulcerative colitis. Gut 7: 32–40
Wright R, Truelove SC (1966b) Serial rectal biopsy in ulcerative colitis during the course of a controlled therapeutic trial of various diets. Am J Dig Dis 11: 847–857
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Malchow, H. (1983). Ätiologische und epidemiologische Aspekte chronisch-entzündlicher Darmerkrankungen. In: Bommer, W., et al. Dünndarm B. Handbuch der inneren Medizin, vol 3 / 3 / B. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68897-3_30
Download citation
DOI: https://doi.org/10.1007/978-3-642-68897-3_30
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-68898-0
Online ISBN: 978-3-642-68897-3
eBook Packages: Springer Book Archive