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Invasive Methoden zur Messung akuter Kontraktilitätsänderungen des Herzens

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Hämodynamisches Monitoring

Zusammenfassung

Bei Bestimmung der kontraktilen Eigenschaften des Herzens kann es grundsätzlich um zwei unterschiedliche Probleme gehen; einmal um die Frage, in welchem kontraktilen Zustand sich ein Herz im Vergleich mit anderen befindet bzw. wieweit sich ein Herz in seiner kontraktilen Güte vom Normalzustand unterscheidet. Dies wäre also ein interindividueller Vergleich.

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Literatur

  1. Baisch F, Kelpin M, Beck L, Schmidt HD (1982) Sensitivity of LVdP/dtmax and stroke volume on preload changes and inotropic interventions in isolated working rat hearts. Pflugers Arch 392:R 2

    Google Scholar 

  2. Bos GC van den (1972) Indices of contractility in the intact heart. Proc R Soc Med 65:545–547

    PubMed  Google Scholar 

  3. Bos GC van den, Elzinga G, Westerhof N, Noble MIM (1973) Problems in the use of indices of myocardial contractility. Cardiovasc Res 7:834–848

    Article  PubMed  Google Scholar 

  4. Bowditch HP (1871) Über die Eigentümlichkeiten, welche die Muskelfasern des Herzens zeigen. Ber Sachs Ges (Akad) Wiss 652–689

    Google Scholar 

  5. Bretschneider HJ, Hellige G (1976) Pathophysiologie der Ventrikelkontraktion — Kontraktilität, Inotropie, Suffizienzgrad und Arbeitsökonomie des Herzens. Verh Dtsch Ges Kreislaufforsch 42:14–30

    PubMed  CAS  Google Scholar 

  6. Burns JW, Covell JW, Ross J Jr (1973) Mechanics of isotonic left ventricular contractions. Am J Physiol 224:725–732

    PubMed  CAS  Google Scholar 

  7. Davidson DM, Covell JW, Malloch CI, Ross J Jr (1974) Factors influencing indices of left ventricle contractility in the conscious dog. Cardiovasc Res 8:299–312

    Article  PubMed  CAS  Google Scholar 

  8. Elzinga G, Noble MIM, Stubbs J (1977) The effect of an increase in aortic pressure upon the inotropic state of cat and dog left ventricles. J Physiol 273:597–615

    PubMed  CAS  Google Scholar 

  9. Furnival CM, Linden RJ, Snow HM (1970) Inotropic changes in the left ventricle: the effect of changes in heart rate, aortic pressure and enddiastolic pressure. J Physiol 211:359–387

    PubMed  CAS  Google Scholar 

  10. Gentzler RD, Hunter AS, Gault JH (1974) Preload dependence of ejection fraction. Am J Cardiol 33:139

    Article  Google Scholar 

  11. Gleason WL, Braunwald E (1962) Studies on the first derivate of the ventricular pressure pulse in man. J Clin Invest 41:80–91

    Article  PubMed  CAS  Google Scholar 

  12. Gobel FL, Jorgensen CR, Kitamuta K, Wang Y (1971) Acute changes in left ventricular pacing in patients with complete heart block. Circulation 44:771–781

    PubMed  CAS  Google Scholar 

  13. Higgins CB, Vatner SF, Franklin D, Braunwald E (1973) Extent of regulation of the heart’s contractile state in the conscious dog by alteration in the frequency of contraction. J Clin Invest 52: 1187–1194

    Article  PubMed  CAS  Google Scholar 

  14. Hoppe H, Schmidt HD, Seitz E (1976) The maximal rate of pressure rise in the right ventricle of isolated canine hearts in isovolumic and auxotonic systole under various hemodynamic and inotropic conditions. Basic Res Cardiol 71:530–541

    Article  PubMed  CAS  Google Scholar 

  15. Jacob R, Gülch R (1972) Kritische Bemerkungen zur Aussagekraft der „Kontraktilitätsindices“. Verh Dtsch Ges Kreislaufforsch 38:241–246

    PubMed  CAS  Google Scholar 

  16. Jacob R, Gülch R, Holubarsch C, Kissling G (1975) Die Bewertung der myokardialen Leistungsfähigkeit. Muskelphysiologische Grundlagen und methodische Probleme. Med Klin 70:1347–1365

    PubMed  CAS  Google Scholar 

  17. Kahn MC, Kavaler F, Fischer VJ (1976) Frequency-force relationship of mammalian ventricular muscle in vivo and in vitro. Am J Physiol 230:631–636

    PubMed  CAS  Google Scholar 

  18. Karliner JS, Gault JH, Bouchard RJ, Holzer J (1974) Factors influencing the ejection fraction and the mean rate of circumferential fibre shortening during atrial fibrillation in man. Cardiovasc Res 8:18–25

    Article  PubMed  CAS  Google Scholar 

  19. Kavaler F, Harris RS, Lee RJ, Fisher VJ (1971) Frequency-force behaviour of in situ ventricular myocardium in the dog. Circ Res 28:533–544

    CAS  Google Scholar 

  20. Koch-Weser J, Blinks JR (1963) The influence of the interval between beats on myocardial contractility. Pharmacol Rev 15:601–652

    PubMed  CAS  Google Scholar 

  21. Koepchen HP (1982) Zentralnervöse und reflektorische Steuerung der Herzfrequenz. In: Brisse B, Bender F (Hrsg) Autonome Innervation des Herzens. Medikamentöse Therapie bradycarder Rhythmusstörungen. Steinkopff, Darmstadt, S 66–85

    Google Scholar 

  22. Koepchen HP, Lux HD, Wagner PH (1961) Untersuchungen über Zeitbedarf und zentrale Verarbeitung des pressorezeptorischen Herzreflexes. Pflugers Arch 273:413–430

    Article  CAS  Google Scholar 

  23. Levine HJ, Britman NA (1964) Force-velocity relations in the intact dog heart. J Clin Invest 43:1383–1396

    Article  PubMed  CAS  Google Scholar 

  24. Limbourg P, Wende W, Heinrich M, Peiper U (1971) Frequenzinotropie und Frank-Starling-Mechanismus am Hundeherzen in situ unter natürlichem und künstlichem Herzantrieb. Pflugers Arch 322:250–263

    Article  PubMed  CAS  Google Scholar 

  25. Mason DT (1969) Usefulness and limitations of the rate of rise of intraventricular pressure (dP/dt) in the evaluation of myocardial contractility in man. Am J Cardiol 23:516–527

    Article  PubMed  CAS  Google Scholar 

  26. Mason DT, Sonnenblick EH, Ross J Jr, Covell JW, Braunwald E (1965) Time to peak dP/dt: A useful measurement of evaluating the contractile state of the human heart. Circulation [Suppl II] 32:145

    Google Scholar 

  27. Mason DT, Sonnenblick EH, Covell JW, Ross J Jr, Braunwald E (1967) Assessment of myocardial contractility in man: Relationship between the rate of pressure rise and developed pressure throughout isometric left ventricular contraction (P). Circulation [Suppl II] 36:183–184

    Google Scholar 

  28. McLaurin LP, Rolett EL, Grossman W (1973) Impaired left ventricular relaxation during pacing-induced ischemia. Am J Cardiol 32:751–757

    Article  PubMed  CAS  Google Scholar 

  29. Mirsky I (1969) A critical review of cardiac function parameters. Circulation [Suppl III] 40:147

    Google Scholar 

  30. Morgenstern C, Arnold G, Höljes U, Lochner W (1970) Die Druckanstiegsgeschwindigkeit im linken Ventrikel als Maß für die Kontraktilität unter verschiedenen hämodynamischen Bedingungen. Pflugers Arch 315:173–186

    Article  PubMed  CAS  Google Scholar 

  31. Morton MJ, McAnulty JH, Rahimtoola SH (1978) Ventricular function curve from a single diagnostic left ventriculogram: Technique, results and value. Am J Cardiol 41:710–717

    Article  PubMed  CAS  Google Scholar 

  32. Noble MIM, Trenchard D, Guz A (1966) Effect of changing heart rate on cardiovascular function in the conscious dog. Circ Res 19:206–213

    Google Scholar 

  33. Noble MIM, Wyler J, Milne ENC, Trenchard D, Guz A (1969) Effect of changes in heart rate on left ventricular performance in conscious dogs. Circ Res 24:285–295

    PubMed  CAS  Google Scholar 

  34. Noble MIM, Stubbs J, Trenchard D, Else W, Eisele JH, Guz A (1972) Left ventricular performance in the conscious dog with chronically denervated heart. Cardiovasc Res 6:457–477

    Article  PubMed  CAS  Google Scholar 

  35. Patterson RE, Kent BB, Peirce II EC (1972) A comparison of empiric contractile indices in intact dogs. Cardiology 57:277–294

    Article  PubMed  CAS  Google Scholar 

  36. Peirce II EC, Kent BB, Patterson RE, Temples J (1970) A curious approximate construction for VCEmax. J Appl Physiol 28:507–509

    PubMed  Google Scholar 

  37. Quinones MA, Gaasch WH, Alexander JK (1976) Influence of acute changes in preload, afterload, contractile state and heart rate on ejection and isovolumic indices of myocardial contractility in man. Circulation 53:293–302

    PubMed  CAS  Google Scholar 

  38. Raff U, Stauber W, Kissling G (1974) Die Aussagekraft verschiedener Kontraktilitätsindices beim Herzen in situ. Basic Res Cardiol 69:58–73

    Article  PubMed  CAS  Google Scholar 

  39. Randall DC (1974) Concurrent measurement of left ventricular dP/dtmax, isometric contractile force and cardiac loading in the intact monkey. Cardiology 59:304–319

    Article  PubMed  CAS  Google Scholar 

  40. Reeck S, Gräber K, Schmidt HD (1978) Vergleich der Inotropieempfindlichkeit mehrerer aktueller Kontraktilitätsparameter. Verh Dtsch Ges Kreislaufforsch 44:205–206

    Google Scholar 

  41. Reeves TJ, Hefner LL, Jones WB, Coghlan C, Prieto G, Carrol J (1960) The hemodynamic determinants of the rate of change in pressure in the left ventricle during isometric contraction. Am Heart J 60:745–761

    Article  PubMed  CAS  Google Scholar 

  42. Reichel H, Rumberger E, Schäfer J, Schwarzkopf HJ, Baumann K (1974) Frequency-potentiation in the human myocardium. Basic Res Cardiol 69:11–20

    Article  PubMed  CAS  Google Scholar 

  43. Ricci DR, Orlick AE, Alderman EL, Ingels NB, Daughters GT, Stinson EB (1979) Influence of heart rate on left ventricular ejection fraction in human beings. Am J Cardiol 44:447–451

    Article  PubMed  CAS  Google Scholar 

  44. Richmond DR, Angus JA, Goodman AH, Cobbin LB (1975) The effect of heart rate on indices of myocardial contractility in the dog. Clin Exp Pharmacol Physiol 2:469–479

    Article  PubMed  CAS  Google Scholar 

  45. Ross J Jr, Covell JW, Sonnenblick EH, Braunwald E (1966) Contractile state of the heart characterized by force-velocity relations in variably afterloaded and isovolumic beats. Circ Res 18:149–163

    Google Scholar 

  46. Sarnoff SJ, Mitchell JH (1962) The control of the function of the heart. In: Hamilton WF, Dow P (eds) Circulation. American Physiological Society, Washington DC (Handbook of physiology, sect 2, vol 1,p 489)

    Google Scholar 

  47. Schaper WKA, Lewi P, Jageneau AHM (1965) The determinants of the rate of change of the left ventricular pressure (dP/dt). Arch Kreislaufforsch 46:27–41

    Article  PubMed  CAS  Google Scholar 

  48. Scher AM (1974) Control of arterial blood pressure. In: Ruch TC, Patton HD (eds) Physiology and biophysics, II. Saunders, Philadelphia London, pp 146–169

    Google Scholar 

  49. Schmidt HD (1969) Die autonome Schrittmacherfrequenz des Hundeherzens. Pflugers Arch 308:137–148

    Article  PubMed  CAS  Google Scholar 

  50. Schmidt HD, Hoppe H (1976) Maximal rate of pressure rise and time parameters in the right ventricle under isovolumic conditions. Basic Res Cardiol 71:521–529

    Article  PubMed  CAS  Google Scholar 

  51. Schmidt HD, Hoppe H (1978) Influence of the contractile state of the heart on the preload dependence of the maximal rate of intraventricular pressure rise dP/dtmax Cardiology 63:112–125

    Article  PubMed  CAS  Google Scholar 

  52. Schmidt HD, Hoppe H (1978) Preload dependence of dP/dtmax, VCEmax and calculated Vmax compared to the inotropic sensitivity of these indices of cardiac contractility. Basic Res Cardiol 73:380–393

    Article  PubMed  CAS  Google Scholar 

  53. Schmidt HD, Scheer RD (1981) Quantitative data on the afterload dependence of left ventricular dP/dtmax in isolated canine hearts. Basic Res Cardiol 76:89–105

    Article  PubMed  CAS  Google Scholar 

  54. Schmidt HD, Hoppe H, Schneider W (1973) Usefulness of some pressure velocity parameters for evaluation of left ventricular contractility. Verh Dtsch Ges Kreislaufforsch 39:151–156

    PubMed  CAS  Google Scholar 

  55. Schmidt HD, Hoppe H, Jotzo R (1975) The inotropic sensitivity of dP/dtmax and ventricular function curves. A comparison study on isolated canine hearts. Pflugers [Suppl] 355:R 15

    Google Scholar 

  56. Schmidt HD, Hoppe H, Müller KD (1979) The effect of changes in cardiac frequency on left and right ventricular dP/dtmax at different contractile states of the myocardium. Eur J Applied Physiol 42:183–198

    Article  CAS  Google Scholar 

  57. Schwarz F, Thormann J (1975) Mechanical and electrical causes of lack of frequency potentiation in normal patients, in coronary artery disease and in left bundle branch block. Eur J Cardiol 2/3:315–320

    PubMed  CAS  Google Scholar 

  58. Siegel JH, Sonnenblick EH (1963) Isometric time-tension relationships as an index of myocardial contractility. Circ Res 12:597–610

    PubMed  CAS  Google Scholar 

  59. Sonnenblick EH (1962) Force-velocity relations in mammalian heart muscle. Am J Physiol 202:931–939

    PubMed  CAS  Google Scholar 

  60. Veragut UP, Krayenbühl HP (1965) Estimation and quantification of myocardial contractility in the closed-chest dog. Cardiologia 47:96–112

    Article  PubMed  CAS  Google Scholar 

  61. Wallace AG, Skinner NS Jr, Mitchell JH (1963) Hemodynamic determinants of the maximal rate of rise of left ventricular pressure. Am J Physiol 206:30–36

    Google Scholar 

  62. Wiggers CJ (1927) Studies on the cardiodynamic actions of drugs. I. The application of optical methods of pressure registration in the study of cardiac stimulants and depressants. J Pharmacol Exp Ther 30:217–231

    CAS  Google Scholar 

  63. Wildenthal K, Mierzwiak DS, Mitchell JH (1969) Effect of sudden changes in aortic pressure on left ventricular dP/dt. Am J Physiol 216:185–190

    PubMed  CAS  Google Scholar 

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© 1983 Springer-Verlag Berlin Heidelberg

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Schmidt, H.D. (1983). Invasive Methoden zur Messung akuter Kontraktilitätsänderungen des Herzens. In: Jesch, F., Peter, K. (eds) Hämodynamisches Monitoring. Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine, vol 156. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68881-2_10

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  • DOI: https://doi.org/10.1007/978-3-642-68881-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-12093-3

  • Online ISBN: 978-3-642-68881-2

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