Molecular Properties of a Factor Inducing Differentiation in Murine Myelomonocytic Leukemic Cells

  • N. A. Nicola
  • M. Matsumoto
  • D. Metcalf
  • G. R. Johnson
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 28)


The possibility of therapeutic manipulation of normal regulatory molecules in leukemia has recently gained interest with the demonstration, both in vivo and in vitro, that terminal differentiation and leukemic stem cell suppression can be induced in several mouse myeloid leukemic cell lines by normal tissue products [2–4, 8, 9].


Normal Bone Marrow Charge Heterogeneity Myelomonocytic Leukemic Cell Bone Marrow Colony Mouse Lung Conditioned Medium 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1983

Authors and Affiliations

  • N. A. Nicola
  • M. Matsumoto
  • D. Metcalf
  • G. R. Johnson

There are no affiliations available

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