Molecular Properties of a Factor Inducing Differentiation in Murine Myelomonocytic Leukemic Cells
The possibility of therapeutic manipulation of normal regulatory molecules in leukemia has recently gained interest with the demonstration, both in vivo and in vitro, that terminal differentiation and leukemic stem cell suppression can be induced in several mouse myeloid leukemic cell lines by normal tissue products [2–4, 8, 9].
KeywordsNormal Bone Marrow Charge Heterogeneity Myelomonocytic Leukemic Cell Bone Marrow Colony Mouse Lung Conditioned Medium
Unable to display preview. Download preview PDF.
- 2.Fibach E, Landau T, Sachs L (1972) Normal differentiation of myeloid leukemic cells induced by a differentiation-inducing protein. Nature 237:276–278Google Scholar