Abstract
Interferon has potent antiviral, anti-proliferative, and immunomodulating properties [9, 10]. Leukocyte and fibroblast interferon have been applied in the treatment of human malignancies. Due to the limited availability of interferon, only small numbers of patients have been treated so far. According to the literature a total of 106 patients with malignant lymphomas have been treated, including five patients with Hodgkin’s disease, 65 patients with multiple myeloma, nine patients with acute lymphatic leukemia, 14 patients with chronic lymphatic leukemia, nine patients with nodular poorly differentiated lymphocytic non-Hodgkin lymphoma, and four patients with diffuse histiocytic non-Hodgkin lymphoma. Eight of the 106 patients achieved complete remission and 56 showed partial regression [1, 2, 4, 5, 7, 8, 12–15].
This study was supported by the Bundesministerium für Technologie und Raumfahrt, Bonn, FRG
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Siegert, W. et al. (1983). Human Interferon-Beta in the Treatment of Non-Hodgkin Lymphoma. In: Neth, R., Gallo, R.C., Greaves, M.F., Moore, M.A.S., Winkler, K. (eds) Modern Trends in Human Leukemia V. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68761-7_12
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DOI: https://doi.org/10.1007/978-3-642-68761-7_12
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