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The Effect of Some Premedicants on the Cardiovascular System

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Cardiovascular Measurement in Anaesthesiology

Part of the book series: European Academy of Anaesthesiology ((ANAESTHESIOLOGY,volume 2))

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Abstract

The acute haemodynamic changes caused by tracheal intubation are well known and several methods have been used to attenuate this response. However, the traditional anticholinergic premedicant, atropine, causes similar changes even without the stimulus of intubation(1). The combination of droperidol with fentanyl is also widely used for premedication but its effects are less well established. Droperidol has an anticholinergic action itself(2) but also attenuates the response to intubation(3). This study was undertaken to investigate the effects of atropine alone, droperidol plus fentanyl, or both in combination on the cardiovascular response to tracheal intubation.

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References

  1. Eikard B and Anersen JR (1977) Arrhythmias during halothane anaesthesia: the influence of atropine. Acta Anaesth Scand 21; 245.

    Article  PubMed  CAS  Google Scholar 

  2. Berghem L, Bergman U, Shildt B and Sörbo B (1980) Plasma atropine concentrations determined by radioimmunoassay after single dose i.v. and i.m. administration. Br J Anaesth 52; 597.

    Article  PubMed  CAS  Google Scholar 

  3. Edmond-Seal J and Prys-Roberts C (1970) Pharmacology of drugs used in neuroleptanalgesia. Br J Anaesth 42; 207.

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  4. Price HL General anaesthetics in the Pharmacological Basis of Therapeutics (eds LS Goodman and A Gilman) 5th edn, p. 100, New York: Macmillan Publishing Co.

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  5. Parmentier P and Dagnielie P (1979) Has droperidol an atropine effect? Br J Anaesth 51; 775.

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  6. Curran J, Crowley M and O’Sullivan G (1980) Droperidol and endotracheal intubation. Anaesthesia 35; 290.

    Article  PubMed  CAS  Google Scholar 

  7. Mirahur RK, Dundee JW and Connoly JDR (1979) Studies of drugs given before anaesthesia XVIII: Anticholinergic premedicants. Br J Anaesth 51; 339.

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© 1982 Springer-Verlag Berlin Heidelberg

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Fassoulaki, A., Kaniaris, P., Kotsanis, S. (1982). The Effect of Some Premedicants on the Cardiovascular System. In: Prys-Roberts, C., Vickers, M.D. (eds) Cardiovascular Measurement in Anaesthesiology. European Academy of Anaesthesiology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68690-0_18

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  • DOI: https://doi.org/10.1007/978-3-642-68690-0_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-11719-3

  • Online ISBN: 978-3-642-68690-0

  • eBook Packages: Springer Book Archive

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