Abstract
The elderly have a known resistance to the beta-adrenergic-mediated responses to exercise and isoprenaline [1]. Ageing is associated with an increase in circulating plasma noradrenaline levels [2], which may compensate for reduced receptor sensitivity, and this increased level of plasma noradrenaline might compete with isoprenaline or propranolol for beta-receptor binding in the heart [3].
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© 1982 Springer-Verlag Berlin Heidelberg
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Williams, B.O. (1982). Mechanism of Action of Combined Treatment with Beta-Blockers and Diuretics in Elderly Hypertensive Patients. In: Lang, E., Sörgel, F., Blaha, L. (eds) Beta-Blockers in the Elderly. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68674-0_4
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DOI: https://doi.org/10.1007/978-3-642-68674-0_4
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