Capacity of Gentamicin-Treated Pseudomonas aeruginosa to Induce Granulocyte Locomotion

  • M. P. Dierich
  • W. Weikel
Conference paper


In protection against an invading parasite the host’s granulocytes play an essential role. To exert their defense the phagocytes have to be attracted to the site of parasite invasion. We have shown that Pseudomonas aeruginosa ATCC 27853 and other clinical isolates of this species can induce granulocyte migration, either directly or via generation of chemotactic activity in serum [1].


Minimal Inhibitory Concentration Pseudomonas Aeruginosa Boyden Chamber Chemotactic Activity Cellulose Nitrate 
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    Dierich, M.P. and W. Weikel, 1981. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene (in press).Google Scholar
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    Dierich, M.P., D. Wilhelmi and G. Till, 1977. Nature 270, 351–352.PubMedCrossRefGoogle Scholar
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    Zigmond, S.H., J.G. Hirsch, 1973. J. Exp. Med. 137, 387–410.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • M. P. Dierich
    • 1
  • W. Weikel
    • 1
  1. 1.Institut für Medizinische MikrobiologieJohannes Gutenberg-Universität Mainz AugustusplatzMainzGermany

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