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Chemistry of Trimethylsilyl Cyanide

  • Chapter
Silicon Reagents for Organic Synthesis

Part of the book series: Reactivity and Structure Concepts in Organic Chemistry ((REACTIVITY,volume 14))

Abstract

Some of the fundamentals of silicon chemistry have been presented in Chapter One. We now consider one of the most versatile of the silicon reagents: trimethylsilyl cyanide (TMS-CN). Its reactivity effectively illustrates one of the fundamentals of silicon chemistry. Specifically, the trimethylsilyl group often reacts as if it were a proton. One might therefore expect TMS-CN to approximate the reactions and toxicity of hydrogen cyanide.

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  1. Department of Chemistry, University of Southern California, 90007, University Park, Los Angeles, CA, USA

    William P. Weber

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  1. William P. Weber
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© 1983 Springer-Verlag Berlin Heidelberg

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Weber, W.P. (1983). Chemistry of Trimethylsilyl Cyanide. In: Silicon Reagents for Organic Synthesis. Reactivity and Structure Concepts in Organic Chemistry, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68661-0_2

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  • DOI: https://doi.org/10.1007/978-3-642-68661-0_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68663-4

  • Online ISBN: 978-3-642-68661-0

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