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Circadian Rhythms of the Isolated Chicken Pineal in Vitro

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Book cover Vertebrate Circadian Systems

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

Behavioral experiments with passerine birds and physiological experiments with the pineal of chickens demonstrate that the avian pineal contains one or more circadian oscillators (for review see, Takahashi and Menaker 1979). In house sparrows, the pineal is necessary for the persistence of circadian rhythmicity (Gaston and Menaker 1968); pineal transplants restore circadian rhythmicity in arrhythmic pinealectomized hosts (Zimmerman and Menaker 1975, Menaker and Zimmerman 1976); and, more importantly, pineal transplants determine the phase of the restored rhythm (Zimmerman and Menaker 1979). These results argue that the pineal functions as a pacemaker within the circadian system of the sparrow.

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References

  • Axelrod J, Zatz M (1977) The β-adrenergic receptor and the regulation of circadian rhythms in the pineal gland. In: Litwack G (ed) Biochemical actions of hormones, vol IV. Academic Press, London New York, pp 249–268

    Google Scholar 

  • Binkley S (1976) Comparative biochemistry of the pineal gland of birds and mammals. Am Zool 16: 57–65

    CAS  Google Scholar 

  • Binkley S, Geller EB (1975) Pineal N-acetyltransferase in chickens: Rhythm persists in constant darkness. J Comp Physiol 99: 67–70

    Article  CAS  Google Scholar 

  • Binkley S, MacBride SE, Klein DC, Ralph C (1973) Pineal enzymes: Regulation of avian melatonin synthesis. Science 181: 273–275

    Article  CAS  Google Scholar 

  • Binkley S, MacBride SE, Klein DC, Ralph C (1975) Regulation of pineal rhythms in chicks: Refractory period and nonvisual light perception. Endocrinology 96: 848–853

    Article  PubMed  CAS  Google Scholar 

  • Binkley SA, Reibman JB, Reilly KB (1978) The pineal gland: A biological clock in vitro. Science 202: 1198–1201

    Article  PubMed  CAS  Google Scholar 

  • Deguchi T (1979) Circadian rhythm of serotonin N-acetyltransferase activity in organ culture of chicken pineal gland. Science 203: 1245–1247

    Article  PubMed  CAS  Google Scholar 

  • Gaston S, Menaker M (1968) Pineal function: The biological clock in the sparrow? Science 160: 1125–1127

    Article  PubMed  CAS  Google Scholar 

  • Kasal C, Menaker M, Perez-Polo R (1979) Circadian clock in culture: N-acetyltransferase activity of chick pineal glands oscillates in vitro. Science 203: 656–658

    Article  PubMed  CAS  Google Scholar 

  • Klein DC (1978) The pineal gland: A model of neuroendocrine regulation. In: Reichlin S, Baldessarini R, Martin JB (eds) The hypothalamus. Raven, New York, pp 303–327

    Google Scholar 

  • Menaker M, Zimmerman N (1976) Role of the pineal in the circadian system of birds. Am Zool 16: 45–55

    CAS  Google Scholar 

  • Pelham RW (1975) A serum melatonin rhythm in chickens and its abolition by pinealectomy. Endocrinology 96: 543–546

    Article  PubMed  CAS  Google Scholar 

  • Ralph CL, Pelham RW, MacBride SE, Reilly DP (1974) Persistent rhythms of pineal and serum melatonin in cockerels in continuous darkness. J Endocrinol 63: 319–324

    Article  PubMed  CAS  Google Scholar 

  • Takahashi JS, Menaker M (1979) Physiology of avian circadian pacemakers. Fed Proc 38: 2583–2588

    PubMed  CAS  Google Scholar 

  • Takahashi JS, Hamm H, Menaker M (1980) Orcadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro. Proc Natl Acad Sci USA 77: 2319–2322

    Article  PubMed  CAS  Google Scholar 

  • Wainwright SD, Wainwright LK (1979) Chick pineal serotonin acetyltransferase: A diurnal cycle maintained in vitro and its regulation by light. Can J Biochem 57: 700–709

    Article  PubMed  CAS  Google Scholar 

  • Wainwright SD, Wainwright LK (1980) Regulation of the cycle in chick pineal serotonin N-acetyltransferase activity in vitro by light. J Neurochem 35: 451–457

    Article  PubMed  CAS  Google Scholar 

  • Zimmerman NH, Menaker M (1975) Neural connections of sparrow pineal: Role in circadian control of activity. Science 190: 477–479

    Article  PubMed  CAS  Google Scholar 

  • Zimmerman NH, Menaker M (1979) The pineal: A pacemaker within the circadian system of the house sparrow. Proc Natl Acad Sci USA 76: 999–1003

    Article  PubMed  CAS  Google Scholar 

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© 1982 Springer-Verlag Berlin · Heidelberg

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Takahashi, J.S. (1982). Circadian Rhythms of the Isolated Chicken Pineal in Vitro. In: Aschoff, J., Daan, S., Groos, G.A. (eds) Vertebrate Circadian Systems. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68651-1_17

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  • DOI: https://doi.org/10.1007/978-3-642-68651-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68653-5

  • Online ISBN: 978-3-642-68651-1

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