Zusammenfassung
Der 1836 von Müller eingeführte Begriff „Bindegewebe“umfaßt Bindegewebstypen von morphologisch äußerst unterschiedlicher Vielfalt; doch sind alle Formen, ausgenommen der Knochen, durch ein einheitliches Bauprinzip gekennzeichnet:
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Literatur
Abe S, Nagai Y (1973) Evidence for the presence of a complex of collagenase with a2-macroglobulin in human rheumatoid synovial fluid: A possible regulatory mechanism of collagenase activity in vivo. J Biochem (Tokyo) 73: 807–900
Abraham PA, Hart ML, Winge AR, Carnes WH (1977) The biosynthesis of elastin by an aortic medial cell culture. In: Sandberg LB, Gray WR, Franzblau C (eds) Elastin and elastic tissue. Plenum Press, New York London, pp 397–411
Adam M, Musilova J, Deyl Z (1976a) Cartilage collagen in osteoarthritis. Clin Chim Acta 69: 53–59
Adam M, Vitasek R, Deyl Z, Felsch G, Musilova J, Olsovka Z (1976b) Collagen in rheumatoid
arthritis. Clin Chim Acta 70:61–69
Ali SY, Bayliss MT (1974) Enzyme changes in human osteoarthritic cartilage. In: Ali SY, Elves MW, Leaback DH (eds) Normal and osteoarthritic articular cartilage. Institute of Orthopaedics, London, p 189
Ali SY, Evans L (1973) Enzymic degredation of cartilage in osteoarthritis. Fed Proc 32: 1494–1498
Alper R, Ruegamer WR (1969) Hormonal effects on the acid mucopolysaccharide composition of the rat aorta. J Atheroscler Res 10: 19–32
Anders RF, Natvig JB, Michaelsen TE, Husby G (1975) Isolation and characterization of amyloid-related serumprotein SAA as a low molecular weight protein. Scand J Immunol 4: 397–401
Anders RF, Nordstoga K, Natvig JB, Husby G (1976) Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink. J Exp Med 143: 678–683
Anders RF, Natvig JB, Sletten K, Husby G, Nordstoga K (1977) Amyloid-related serumprotein SAA from 3 animal species; comparison with human SAA. J Immunol 118: 229–234
Anderson JC (1976) Glycoproteins of the connective tissue matrix. In: Hall DA, Jackson DS (eds) International review of connective tissue research, vol 7. Academic Press, New York San Francisco London, pp 251–322
Andriopoulos NA, Mestecky J, Miller EJ, Bradly EL (1976) Antibodies to native and denatured collagens in sera of patients with rheumatoid arthritis. Arthritis Rheum 19: 613–617
Anseth A (1969) Studies on corneal polysaccharides. V. Changes in cornea glycosaminoglycans in transient stromal edema. Exp Eye Res 8: 297–301
Antoniades HN, Scher DC (1977) Radioimmunoassay of a human serum growth factor for Balb/C- 3T3 cells: derivation from platelets. Proc Natl Acad Sei USA 74: 1973–1977
Antony PP, Ishak KG, Nayak NC, Poulson HE, Scheuer PJ, Sobin LH (1977) The morphology of cirrhosis: definition, nomenclature, and classification. Bull WHO 55 (4): 521–540
Arnold G, Gressner AM (1977) Zur experimentellen Rheologie des Leberparenchyms. Biomed Tech (Berlin) 22: 182–186
Arnold G, Gressner AM (1977) Zur experimentellen Rheologie des Leberparenchyms. Biomed Tech (Berlin) 22: 182–186
Arnott S, Guss JM, Hukins DWL, Mathews MB (1973b) Mucopolysaccharides: comparison of chondroitin sulfate conformations with those of related polyanions. Science 180: 743–745
Arnott S, Guss JM, Hukins DWL, Dea ICM, Rees DA (1974) Conformation of keratan sulfate. A study of stereo-chemical relationships within the glycosaminoglycan family. J Mol Biol 88: 175–185
Aronson NN, Davidson EA (1968) Catabolism of mucopolysaccharides by rat liver lysosomes in vivo. J Biol Chem 243: 4494–4499
Asboe-Hansen G (1966) Hormones and connective tissue. Munksgaard, Kopenhagen
Asboe-Hansen G (1969) Hormone control of connective tissue. Br J Dermatol [Suppl II] 81: 2–8
Ashton IK, Francis MJO (1977) An assay for plasma somatomedin: (3H) thymidine incorporation by isolated rabbit chondrocytes. J Endocrinol 74: 205–212
Atkins D, Zanelli JM, Peacock M, Nordin BEC (1972) The effect of oestrogens on the response of bone to parathyroid hormone in vitro. J Endocrinol 54: 107–116
Atkins EDT, Hardingham TE, Isaac DH, Muir H (1974) X-ray fiber diffraction of cartilage proteoglycan aggregates containing hyaluronic acid. Biochem J 141: 919–921
Atkins EDT, Laurent TC (1973) X-ray-diffraction patterns from chondroitin 4-sulphate, dermatan sulphate and heparan sulphate. Biochem J 133: 605–606
Atkins EDT, Sheehan JK (1972) Structure of hyaluronic acid. Nature New Biol 235: 253–254
Attaiah AA, Lee JB (1973) Specific binding sites in the rabbit kidney for prostaglandin A. Prostaglandins 4: 703–709
Audhya TK, Gibson KD (1975) Enhancement of somatomedin titers of normal and hypopituitary sera by addition of L-triiodothyronine in vitro at physiological concentrations. Proc Natl Acad Sei USA 72: 604–608
Audhya TK, Gibson KD (1976) Effects of medium composition and metabolic inhibitors von glycos- aminoglycan synthesis chick embryo cartilage and its stimulation by serum and triiodothyronine. Biochim Biophys Acta 437: 364–376
Audhya TK, Segen BJ, Gibson KD (1976) Stimulation of proteoglycan synthesis in chick embryo sternum by serum and L-3,5,3-triiodothyronine. J Biol Chem 251: 3763–3767
Avila JL, Convit J (1975) Inhibition of leucozytic lysosomal enzymes by glycosaminoglycans in vitro. Biochem J 152: 57–64
Avila JL, Convit J (1976) Physicochemical characteristics of the glycosaminoglycan-lysosomal enzyme interaction in vitro. Biochem J 160: 129–136
Axelsson I, Heinegard D (1978) Fractionation of proteoglycans from bovine corneal stroma. Biochem J 145: 491–500
Ayer JP (1964) Elastic tissue. Int Rev Connect Tissue Res 2: 33–100
Babior BM, Kipnes RS, Curnutte JT (1973) Biological defence mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest 52: 741–744
Bach G, Friedman R, Weissmann B, Neufeld EF (1972) The defect in the Hurler and Scheie syndromes: deficiency of a-L-iduronidase (skin fibroblasts/mucopolysaccharidosis). Proc Natl Acad Sei USA 69: 2048–2051
Bach G, Eisenberg F, Cantz M, Neufeld EF (1973) The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase. Proc Natl Acad Sei USA 70: 2134–2138
Bailey HJ, Sims TJ, Duance VC, Light D (1979) Partial characterization of a second basement membrane collagen in human placenta. Evidence for the existence of two type IV collagen molecu¬les. FEBS Lett 99: 361–366
Baker JR, Cifonelli JA, Roden L (1975) The linkage of corneal keratan sulfate to protein. Connect Tissue Res 3: 149–156
Balasubrahmanyan M (1953) The ground substance of the fibrous tissue in experimental liver cirrhosis. J Pathol Bacteriol 65: 123–128
Balazs EA (1977) Interaction between cells, hyaluronic acid and collagen. Ups J Med Sei 82: 94
Balazs M, Varkonyi S, Juhasz J (1973) Elektronenmikroskopische Untersuchungen in Fällen von chronisch-aggressiver Hepatitis. Acta Hepatogastroenterol (Stuttg) 20: 399–409
Balazs M, Varkonyi S, Juhasz J (1973) Elektronenmikroskopische Untersuchungen in Fällen von chronisch-aggressiver Hepatitis. Acta Hepatogastroenterol (Stuttg) 20: 399–409
Balleisen L, Gay S, Marx R, Kühn K ( 1975 b) Comparative investigation of the influence of bovine collagen types I, II and III on the aggregation of human platelets. Klin Wochenschr 53: 903–905
Banga I (1966) Structure and function of elastin and collagen. Akademiai Kiado, Budapest
Barrett AI (1975) Lysosomal proteinases. In: Reich E, Rifkin D, Shaw E (eds) Cold Spring Habor Symposium on proteases and biological control, Cold Spring Habor. Cold Spring Habor Press, New York
Bartsocas C, Grobe H, Kamp JJP van de, Figura K von, Kresse H, Klein U, Biesberts MAH (1979) Sanfilippo Type C disease: Clinical findings in four patients with a new variant of mucopolysaccharidosis III. Eur J Pediatr 130: 251–258
Bartsocas C, Grobe H, Kamp JJP van de, Figura K von, Kresse H, Klein U, Biesberts MAH (1979) Sanfilippo Type C disease: Clinical findings in four patients with a new variant of mucopolysaccharidosis III. Eur J Pediatr 130: 251–258
Bashey RI, Perlish JS, Nochumson S, Stephens RE, Fleischmajer R (1977b) Connective tissue synthe¬sis by cultured scleroderma fibroblasts. Arthritis Rheum 20: 879–885
Baum BJ, Moss J, Breul SC, Crystal RG (1978) Association in normal human fibroblasts of eleveted levels of adenosine 3‘: 5‘-monophosphate with a selective decreases in collagen production. J Biol Chem 253: 3391–3394
Bavetta LA, Bekhor I, Nimni ME (1962) Effects of hormone administration on collagen biosynthesis in the rat. Proc Soc Exp Biol Med 110: 294–297
Bayliss MT, Ali SY (1978) Age-related changes in the composition and structure of human articular-cartilage proteoglycans. Biochem J 176: 683–693
Beard HK, Faulk WP, Conochie LB, Glynn LE (1977) Some immunological aspects of collagen. Prog Allergy 22: 45–106
Becker EL, Henson PM (1973) In vitro studies of immunologically induced secretion of mediators from cells and related phenomena. Adv Immunol 17: 93–193
Becker K (1968) Biochemische Untersuchungen zum Bindegewebsstoffwechsel bei menschlicher und experimenteller Leberzirrhose. Dtsch Z Verdau Stoffwechselkr 28: 161–162
Becker K (1969) Untersuchungen zur chemischen Beschaffenheit des Bindegewebes der Leber bei der Leberzirrhose. Z Gesamte Exp Med 151: 1–9
Becker K (1975) Metabolie studies of hepatic connective tissue contituents. In: Popper H, Becker K (eds) Collagen metabolism in the liver. Stratton Intercontinental, New York, pp 45–52
Bellamy G, Bornstein P (1971) Evidence for procollagen. A biosynthetic precursor of collagen. Proc Natl Acad Sei USA 68: 1138–1142
Beneke G (1974) Allgemeine Pathologie der Interzellularsubstanz. In: Sandritter W, Beneke G (Hrsg) Allgemeine Pathology. Schattauer, Stuttgart New York, S 226–298
Bengtsson G, Olivecrona T, Höök M, Lindahl U (1977) Interaction of heparin with proteins: demonstration of different binding sites for antithrombin and lipoprotein lipase. FEBS Lett 79: 59–63
Benson MD, Aldo-Benson MA, Shirahama T, Borel Y, Cohen HS (1975) Suppression of in vitro antibodies response by a serum factor ( SAA) in experimentally induced amyloidosis. J Exp Med 142: 236–241
Benson MD, Cohen AS, Howard A, Bywaters E, Ansell B (1976) Amyloid protein SAA levels in juvenile rheumatoide arthritis. Arthritis Rheum 19: 789
Benson MD, Scheinberg MA, Shirahama T, Cathart ES, Skinner M (1977) Kinetics of SAA (serum amyloid protein) in casein-induced murine amyloidosis. J Clin Invest 59: 412–418
Bentz H, Glanville R, Kühn K (1978) Type V collagen: a molecule with a chain composition a A (OCB)2. In: International Colloquium of CNRS, vol 287, p 201, Creteil
Benya PD, Nimni ME (1979) The stability of the collagen phenotype during stimulated collagen, glycosaminoglycan, and DNA synthesis by articular cartilage organ cultures. Arch Biochem Bio- phys 192: 327–335
Berenson GS, Serra MT (1959) Mucopolysaccharides in urine from patientss with Marfan-syndrome. Fed Proc 18: 190
Berenson GS, Serra MT (1959) Mucopolysaccharides in urine from patientss with Marfan-syndrome. Fed Proc 18: 190
Berg RA, Prockop DJ ( 1973 b) The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing. The triple-helix of collagen. Biochem Biophys Res Commun 52: 115–120
Berlinguet L, Normand A (1968) Effects of polyamino acids, histones and heparin on a amino acid incorporation into ribosomal proteins from rat liver. Biochim Biophys Acta 161: 509–517
Beuttel SC, Eisenbarth GS, Lebovitz HE (1977) Amino acid dependent and independent insulin stimulation of cartilage metabolism. Biochemistry 16: 5759–5764
Bhavanandan VP, Davidson EA (1975) Mucopolysaccharides associated with nuclei of cultured mammalian cells. Proc Natl Acad Sei USA 72: 2032–2036
Bhavanandan VP, Meyer K (1968) Studies on keratosulfates. J Biol Chem 243: 1052–1059
Bianco NE, Dobkin LW, Schur PH (1974) Immunological properties of isolated IgG and IgM anti-gammaglobulins (rheumatoid factor). Clin Exp Immunol 17: 91–101
Biempica L, Morecki R, Wu CH, Giambrone MA, Kojkind M (1977) Isolation and immunohisto- chemical localization of a component of basement membrane collagen in human liver. Gastroenterology 73: 1213
Birkedal-Hansen H, Cobb CM, Taylor RE, Fullmer HM (1976) Synthesis and release of procollage-nase by cultured fibroblasts. J Biol Chem 251: 3162–3168
Black-Schaffer B (1957) Infantile endocardial fibroelastosis. AMA Arch Pathol 63: 281–306
Blackham A, Farmer JB, Radziwonik H, Westwick J (1974) The role of prostaglandins in rabbit monoarticular arthritis. Br J Pharmacol 51: 35–44
Blobel G, Dobberstein B ( 1975 a) Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nasent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. J Cell Biol 67: 835–851
Blobel G, Dobberstein B ( 1975 b) Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components. J Cell Biol 67: 852–862
Blumenkrantz N, Asboe-Hansen G (1976) High molecular collagen peptide fraction in urine indicates disease activity in generalized scleroderma. Acta Derm Venerol (Stockh) 56: 415–121
Blumenkrantz N, Sondergaard J (1972) Effect of prostaglandins Et and Fi on biosynthesis of collagen. Nature 239: 246
Boaz NJ, Foley JB (1954) Effects of growth, fasting and trauma on the concentrations of connective tissue hexosamine and water. Proc Soc Exp Biol Med 86: 690 - 693
Boedtker H, Crkvenjakov RB, Last JA, Doty P (1974) The identification of collagen messenger RNA. Proc Natl Acad Sei USA 71: 4208–4212
Boedtker H, Frischauf AM, Lehrach H (1976) Isolation and translation of calvaria procollagen messenger ribonucleic acids. Biochemistry 15: 4765–4770
Bolande RP (1963) The nature of the connective tissue abiotrophy in the Marfan-syndrome. Lab Invest 12: 1087–1093
Bollet AJ, Handy JR, Sturgill BC (1963) Chondrocyte sulphate concentration and protein-polysaccha-ride composition of articular cartilage in osteoarthritis. J Clin Invest 42: 853–859
Bollet AJ, Nance JL (1966) Biochemical findings in normal and osteoarthritic articular cartilage. II. Chondroitin sulphate concentration and chain length, water and ash content. J Clin Invest 45: 1170–1177
Bonnet F, Perin J-P, Jolles P (1978) Isolation and chemical characterization of two distinct „link protein“from bovine nasal cartilage proteoglycan complex. Biochim Biophys Acta 532: 242 - 248
Bonta IL (1978) Endogenous modulators of the inflammatory response. In: Vane JR, Ferreira SH
eds) Inflammation. Springer, Berlin Heidelberg New York, pp 523–567
Bornens N (1973) Action of heparin on nuclei: solubilization of chromatin enabling the isolation of nuclear membrane. Nature 244: 28–30
Bornstein P (1974) The biosynthesis of collagen. Annu Rev Biochem 43: 569–603
Bornstein P (1976) Disorders of connective tissue function and the aging process: a synthesis and review of current concepts and findings. Mech Ageing Dev 5: 305–314
Bornstein P, Ash JF (1977) Cell surface - associated structural proteins in connective tissue cells. Proc Natl Acad Sei USA 74: 2480–2484
Boucek RJ, Noble NL (1961) Metabolism of collagen. Appearance and disappearance of 14C-hydro-xylasine in rat connective tissue. Biochem J 80: 148–154
Bourne HR, Lichtenstein LM, Melmon KL, Henney CS, Weinstein Y, Shearer GM (1974) Modulation of inflammation and immunity by cyclic AMP: receptors for vasoactive hormones and mediators on inflammation regulate many leukocyte functions. Science 184: 19–28
Brady AH (1975) Collagenase in scleroderma. J Clin Invest 56: 1175–1180
Brandt KD (1970) Modification of Chemotaxis by synovial fluid hyaluronate. Arthritis Rheum 13: 308–309
Brandt KD (1974) The effect of synovial hyaluronate on the ingestion of monosodium urate crystals by leukocytes. Clin Chim Acta 55: 307–315
Braun-Falco O (1957) Über das Verhalten der interfibrillären Grundsubstanz bei Sklerodermie. Dermatol Wochenschr 136: 1085–1092
Bray BA, Lieberman R, Meyer K (1967) Structure of human skeletal keratosulphate. The linkage region. J Biol Chem 242: 3373–3380
Breitkreutz D, Diaz De Leon L, Paglia L, Zeichner M, Wilczek J, Stern R (1978) The synthesis of presumptive procollagen messenger ribonucleic acid in the calvaria of the developing chick embryo. Biochim Biophys Acta 517: 349–359
Brimacombe JS, Webber JM (1964) Mucopolysaccharides. Chemical structure, distribution and isolation. Elsevier, Amsterdam
Brodehl J (1961) Thioacetamid in der experimentellen Leberforschung. Klin Wochenschr 39: 956–962
Brosnan ME, Sirek OV, Sirek A, Przybylska K (1973) Action of growth hormone and thyroxine on aortas of hypophysectomized dogs. Diabetes 22: 243–250
Brown MS, Faust JR, Goldstein JL (1975) Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts. J Clin Invest 55: 783–793
Bucher NLR, Malt RA (1971) Regeneration of liver and kidney. Little, Brown Company, Boston
Buck CA, Fuhrer JP, Soslau G, Warren L (1974) Membrane glycopeptides from subcellular fractions of control and virus-transformed cells. J Biol Chem 249: 1541–1550
Buckingham RP, Prince RK, Rodnan GP, Taylor F (1978) Increased collagen accumulation in dermal fibroblasts cultures from patients with progressive systemic sclerosis (scleroderma). J Lab Clin Med 92: 5–21
Buddecke E (1966) Polysaccharide und Polysaccharidsulfate des Bindegewebes. Ilia. Hormone im Polysaccharidstoffwechsel. In: Bartelheimer H, Heyde W, Thorn W (Hrsg) D-Glucose und verwandte Verbindungen in Medizin und Biologie. Enke, Stuttgart, S 593–595
Buddecke E, Segeth G, Kresse H (1973) Age dependent changes of 14C- and 35S-incorporation into ox aorta glycosaminoglycans. In: Vogel HG (ed) Connective tissue and ageing. Excerpta Medica, Amsterdam, pp 62–67
Buonassi V (1973) Sulfated mucopolysaccharide synthesis and secretion in endothelial cell cultures. Exp Cell Res 76: 263
Burgeson RE, El Adli FE, Kaitila J, Hollister DW (1976) Fetal membrane collagens: identification of two new collagen alpha chains. Proc Natl Acad Sei USA 73: 2579–2583
Burgeson RE, Hollister DW (1979) Collagen heterogeneity in human cartilage: identification of several new collagen chains. Biochem Biophys Res Commun 87: 1124–1131
Burke JM, Balian G, Ross R, Bornstein P (1977) Synthesis of types I and III procollagen and collagen by monkey aortic smooth muscle cells in vitro. Biochemistry 16: 3243–3249
Burns TM, Spears CL, Kerwar SS (1973) Further studies on the cell - free synthesis of procollagen - collagen by chick embryo polysomes. Arch Biochem Biophys 159: 880–894
Butler WT (1978) The carbohydrate of collagen, vol 2. In: Horowitz MI, Pigman W (eds) The glycoconjugates. Academic Press, New York San Francisco London, pp 79–85
Bywaters EGL, Ansell BM (1976) Amyloidosis in chronic rheumatic diseases. In: Wegelius O, Paster-nack A (eds) Amyloidosis. Academic Press, New York London, pp 409–417
Cameron GR, Karunaratne WAE (1936) Carbon tetra chloride cirrhosis in relation to liver regeneration. J Pathol Bacteriol 92: 1–22
Caputo CB, Meadows D, Raisz LG (1976) Tailure of estrogens and androgens to inhibit bone resorption in tissue culture. Endocrinology 98: 1065–1068
Cardinale I J, Rhoads RI, Udenfriend S (1971) Simultaneous imcorporation of 180 into succinate and hydroxyproline catalyzed by collagen proline hydroxylase. Biochem Biophys Res Commun 43: 537–543
Carnes WH (1968) Copper and connective tissue metabolism. Int Rev Connect Tissue Res 4: 197–232
Carnutte JT, Babior BM (1974) Biological defense mechanisms: The effect of bacteria and serum on superoxide production by granulocytes. J Clin Invest 53: 1662–1672
Castillo L, Tanaka J, Detuca HF, Sunde ML (1977) The stimulation of 25-hydroxy vitamin D3-loc-hydroxylase by estrogen. Arch Biochem Biophys 179: 211–217
Castor CW (1971a) Abnormalities of connective tissue cells cultured from patients with rheumatoid arthritis. II. Defective regulation of hyaluronate and collagen formation. J Lab Clin Med 77: 65–75
Castor CW (1971b) Connective tissue activation. I. The nature, specifity, measurement and distribu¬tion of connective tissue activating peptide. Arthritis Rheum 14: 41–54
Castor CW (1975 a) Synovial cell activation induced by a polypeptide mediator. Ann NY Acad Sei 256:304–317
Castor CW (1975b) Connective tissue activation: VII. Evidence supporting a role for prostaglandins and cyclic nucleotides. J Lab Clin Med 85: 392–404
Castor CW (1975c) Connective tissue activation. IX. Modification by pharmacologic agents. Arthritis Rheum 18: 451–560
Castor CW, Dorstewitz EL (1966) Abnormalities of connective tissue cells cultured from patient with rheumatoid arthritis. I. Relative unresponsiveness of rheumatoid synovial cells to hydrocortisone. J Lab Clin Med 68: 300–313
Castor CW, Lewis RB (1975) Connective tissue activation. X. Current studies of the process and its mediators. Scand J Rheumatol [Suppl 12] 5: 41–54
Castor CW, Ritchie JC, Scott ME, Whitney SL (1977b) Connective tissue activation. XI. Stimulation of glycosaminoglycan and DNA formation by a platelet factor. Arthritis Rheum 20: 859–867
Castor CW, Ritchie JC, Williams CH, Oegama TR (1975) Connective tissue activation: evidence for multiple connective tissue activating peptides. Clin Res 23:527 A
Castor CW, Ritchie JC, Williams CH, Scott ME, Whitney SL, Myers SL, Sloan TB, Anderson BE (1979) Connective tissue activation. XIV. Composition and actions of a human platelet anta- coid mediator. Arthritis Rheum 22: 260–272
Castor CW, Scott ME, Ritchie JC, Whitney SL (1976) Characteristics of a human platelet factor which stimulates DNA and glycosaminoglycan synthesis. Clin Res 24:575 A
Castor CW, Scott ME, Ritchie JC, Whitney SL (1977a) Connective tissue activation: stimulation of DNA and glycosaminoglycan synthesis by a platelet factor. Arthritis Rheum 20: 110
Castor CW, Whitney SL (1978) Connective tissue activation. XIII. Stimulation of sulfated glycosaminoglycan synthesis in human connective tissue cells by peptide mediators from lymphocytes and platelets. J Lab Clin Med 91: 811–821
Cembrano I, Lillo M, Val J, Mardones I (1960) Influence of sex differences and hormones on elastin and collagen in the aorta of chickens. Circ Res 8: 527–529
Chang W-Ch, Abe M, Murota S (1977) Stimulation by prostaglandin F2a of acidic glycosaminoglycan production in cultured fibroblasts. Prostaglandins 13: 55–63
Chase LR, Fedack SA, Aurbach GD (1969) Activation of skeletal adenyl cyclase by parathyroid hormone in vitro. Endocrinology 84: 761–768
Chatelet LR de, McCall CE, McPhail LC, Johnston RB Jr (1974) Superoxide dismutase activity in leukocytes. J Clin Invest 53: 1197–1201
Chayen I, Bitewsky L (1969) Multiphase chemistry in cell injury. In: Bitter EE, Bitter N (eds) The biological basis of medicine, vol 1. Academic Press, London, pp 337–364
Chen TL, Feldman D (1978) Distinction between alpha-fetoprotein and intracellular estrogen receptors: evidence against the presence of estradiol receptors in rat bone. Endocrinology 102: 236–244
Chochinov RH, Daughaday WH (1976) Current concepts of somatomedin and other biologically related growth factors. Diabetes 25: 994–1004
Choi HU, Meyer K (1975) Keratan sulfate of cartilage and nucleus pulposus. In: Slavkin HC, Greulich RC (eds) Extracellular matrix influences on gene expression. Academic Press, New York San Francisco London, pp 409–414
Chung E, Miller EJ (1974) Collagen polymorphism: Characterization of molecules with the chin composition [al(III)]3 in human tissues. Science 183: 1200–1201
Chung E, Rhodes RK, Miller EJ (1976) Isolation of three collagenous components of probable basement membrane origin from several tissues. Biochem Biophys Res Commun 71: 1167–1174
Chvapil M, Hurych J (1968) Control of collagen biosynthesis. In: Hall DA (ed) International review of connective tissue research, vol 4. Academic Press, New York London, pp 67–196
Cleland RL, Sherblom AP (1977) Isolation and physical characterization of hyaluronic acid prepared from bovine nasal septum by cetylpyridinium chloride precipitation. J Biol Chem 252: 420–426
Coffey JW, Fiedler-Nagy C, Georgiadis AG, Salvador RA (1976) Digestion of native collagen, denatured collagen, and collagen fragments by extracts of rat liver lysosomes. J Biol Chem 251: 5280–5282
Cohen AS (ed) (1975) Laboratory diagnostic diseases, 2. Aufl. Little, Brown and Company, Boston
Cohen AS (1976a) Amyloidosis. In: Buchanan WW, Dick WC (eds) Recent advances in rheumatology. Churchill Livingstone, Edinburgh London New York, pp 19–38
Cohen AS, Calkins E (1959) Electron microscopic observations on fibrous component in amyloid of diverse origons. Nature 183: 1202–1203
Cohen AS, Cathcart ES (1972) Casein-induced experimental amyloidosis. I. Review of cellular and immunologic aspects. Methods Achiev Exp Pathol 6: 207–242
Cohen AS, Cathcrart ES (1974) Amyloidosis and immunoglobulins. Adv Intern Med 19: 41–55
Cohen KL, Nissley SP (1975) Comparison of somatomedin activity in rat serum and lymph. Endocrinology 97: 654–658
Cohen KL, Short PA, Nissley SP (1975) Growth hormonedependent serum stimulation of DNA synthesis in chick embryo fibroblasts in culture. Endocrinology 96: 193–198
Cohen T (1976b) Are homozygotes for HLBA 27 more susceptible to ankylosing spondylitis N Engl J Med 295: 342 - 343
Collins JF, Crystal RG (1975) Characterization of cell-free synthesis of collagen by lung polysomes in a heterologous system. J Biol Chem 250: 7332–7342
Comper WD, Laurent C (1978) Physiological function of connective tissue polysaccharides. Physiol Rev 58: 255
Cook RI, Aikawa M (1973) The effects of heparin on endogenous DNA polymerase activity of rat liver nuclei and chromatin fractions. Exp Cell Res 78: 257–270
Corvol MT, Dumontier MF, Garabedian M, Rappaport R (1978) Vitamin D and cartilage. II. Biological activity of 25-hydroxycholecalciferol and 24,25- and 1,25-dihydroxycholecalciferol on cultured growth plate chondrocytes. Endocrinology 102: 1269–1274
Coulombre AJ, Coulombre JL (1964) Exp Eye Res 3: 105
Coupar BEH, Chesterton CJ (1977) The mechanism by which heparin stimulates transcription in isolated rat liver nuclei. Eur J Biochem 79: 525–533
Cutroneo KR, Counts DF (1975) Anti-inflammatory steroids and collagen metabolism: glucocorti- coid-mediated alterations of prolyl hydroxylase activity and collagen synthesis. Mol Pharmacol 11: 632–639
Cutroneo KR, Costello D, Fuller GC (1971) Alteration of proline hydroxylase activity by glucocor- licoids. Biochem Pharmacol 20: 2797–2804
Cutroneo KR, Newman RA, Prichard PM, Guzman MA, Sharawy MM (1977) Localization of collagen synthesizing ribosomes on the dense segments of the endoplasmic reticulum. Int J Bio- chem 8: 421–426
Damle SP, Kieras FJ, Tzeng W-K, Gregory JD (1979) Isolation and characterization of proteochon-droitin sulfate from pig skin. J Biol Chem 254: 1614–1620
Danishefsky I (1974) Preparation of heparin-linked agarose and its interaction with plasma. Thromb Res 4: 237
Danks DM, Campbell PE, Stevens DJ, Mayne V, Cartwright E (1972) Menkes‘s kinky hair syndrome: an inherited defect in copper absorption with widespread effects. Pediatrics 50: 188–201
Darzynkiewicz Z, Balazs EA (1971) Effect of connective tissue intercellular matrix on lymphocyte stimulation. Exp Cell Res 66: 113–123
Daughaday WH, Hall K, Raben MS, Salmon WD Jr, Brande JL van den, Wyk JJ van (1972) Somatomedin: proposed designation for sulphation factor. Nature 235: 107
David G, Bernfield NR (1979) Collagen reduces glycosaminoglycan degradation by cultured mammalian epithelial cells. Possible mechanism for basal laminau formation. Proc Natl Acad Sei USA 76: 786–790
Davidson EA (1964) Hormonal control of connective tissue metabolism. In: Proc 2nd Int Congr Endocrinol Par I London, pp 398–401
Davidson EA (1965) Conformation of the iduronic acid moiety of chondroitin sulfate B (Dermatan Sulfate). Biochim Biophys Acta 101: 121–124
Davidson EA, Small W (1963a) Metabolism in vivo of connective tissue mucopolysaccharides. II. Chondroitin sulfate B and hyaluronic acid of skin. Biochim Biophys Acta 69: 453–458
Davidson EA, Small W (1963a) Metabolism in vivo of connective tissue mucopolysaccharides. II. Chondroitin sulfate B and hyaluronic acid of skin. Biochim Biophys Acta 69: 453–458
Davidson JM, McEneany LSG, Bornstein P (1977) Intermediates in the conversion of procollagen to collagen. Eur J Biochem 81: 349–355
Day CE, Powell JR, Levy RS (1975) Artery 1: 126
Dayer J-M, Russell RGG, Krane SM (1977) Collagenase production by rheumatoid synovial cells: stimulation by a human lymphocyte factor. Science 195: 181–183
Dehrn P, Jimenez SA, Olsen BR, Prockop DJ (1972) A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH2-terminal extension and evidence suggesting the presence of cystine in the molecule. Proc Natl Acad Sei USA 69: 60–64
Delbrück A (1968) Saure Glykosaminoglykane des normalen und zirrhotischen Leberbindegewebes vom Menschen. Z Klin Chem Klin Biochem 6: 460–466
Delbrück A (1974) Über die Einwirkung von Pyridinolcarbamat auf die Bildung saurer Glykosaminoglykane und Kollagen im Bindegewebe der experimentellen Leberzirrhose der Ratte. Z Klin Chem Klin Biochem 12: 313–320
Luca HF (1976) Metabolism of vitamin D: Current status. Am J Clin Nutr 29: 1258–1270
Denko CW (1976) 35S and 3H-proline incorporation in rats deficient in essential fatty acids. J Rheumatol 3:205–211
Deshmukh K, Hemrick S (1976) Metabolic changes in rabbit articular cartilage due to inflammation. Arthritis Rheum 19: 199–208
Deshmukh K, Nimni ME (1969) A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. II. Functional groups involved in the interaction process. J Biol Chem 244: 1787–1795
Deshmukh K, Sawyer BD (1977) Synthesis of collagen by chondrocytes in suspension culture: Modulation by calcium, 3‘: 5‘-cyclic AMP, and prostaglandins. Proc Natl Acad Sei USA 74: 3864–3868
Dessau W, Sasse J, Timpl R, Zilck F, Mark K von der (1978) Synthesis and extracellular deposition of fibronectin in chondrocyte cultures. Response to the removal of extracellular cartilage matrix. J Cell Biol 79: 342–355
Detenbeck LC, Jowsey J (1969) The effect of thyroidectomy and parathyroidectomy in the remodelling of bone defects in adult dogs. Clin Orthop 65: 199–202
Deyl Z, Rosmus J, Adam H (1972) Hormonal control of collagen ageing. Exp Gerontol 7: 37–43
Deyl Z, Rosmus J, Adam M (1976) Pitnitary and collagen. In: Everitt AV, Burgess JA (eds) Hypothalamus pitnitary and aging. Ill, Thomas, Springfield, pp 171–192
Diaz de Leon L, Paglia L, Breitkreutz D, Stern R (1977) Evidence that the messenger RNA for collagen is monocistronic. Biochem Biophys Res Commun 77: 11–19
Diegelmann RF, Bernstein L, Peterkofsky B (1973) Cell-free collagen synthesis on membrane - bound polysomes of chick embryo connective tissue and the localisation of prolylhydroxylase on the polysome - membrane complex. J Biol Chem 248: 6514–6521
Dietrich CP, Sampaio LO, Toledo OMS (1976) Characteristic distribution of sulfated mucopolysaccharides in different tissues and in their respective mitochondria. Biochem Biophys Res Commun 71: 1–10
DiFerrante N, Leachman RD, Angelini P, Donnelly PV, Francis G, Almazan A, Segni G (1975) Lysyloxidase deficiency in Ehlers-Danlos-syndrome type V. Connect Tissue Rev 3: 49
Dobberstein B, Blobel G (1977) Functional interaction of plant ribosomes with animal microsomen membranes. Biochem Biophys Res Commun 74: 1675–1682
Doherty NS, Saarni H (1976) Stimulation of hydrocortisone of the rate of collagen synthesis in cultured fibroblasts. J Pharm Pharmacol 28: 656–657
Dorfman A, Matalon R (1976) The mucopolysaccharidoses. Proc Natl Acad Sci USA 73: 630–637
Dorfman A, Schiller S (1958) Effects of hormones on the metabolism of acid mucopolysaccharides of connective tissue. Recent Prog Horm Res 14: 427–456
Duance VC, Restall DJ, Beard H, Bourne FJ, Bailey AJ (1977) The location of three collagen types in sceletal muscle. FEBS Lett 79: 248–252
Duksin D, Bornstein P (1977) Impaired conversion of procollagen to collagen by fibroblasts and bone treated with tunicamycin, an inhibitor of protein glycosylation. J Biol Chem 252: 955–962
Eberhard A, Laas U, Vojtisek O, Greiling H (1972a) Lysosomale Enzymverteilungsmuster in der Synovialfliissigkeit bei chronischen Gelenkerkrankungen. Z Rheumaforsch [Suppl 2] 31: 70–76
Eberhard A, Laas U, Vojtisek O, Greiling H (1972b) Zur Bedeutung und Herkunft von lysosomalen Enzymen in der Synovialfliissigkeit bei chronischen Gelenkerkrankungen. Z Rheumaforsch 31: 105–118
Ebert PS, Prockop DJ (1967) Influence of Cortisol on the synthesis of sulphated mucopolysaccharides and collagen in chick embryos. Biochim Biophys Acta 136: 45–55
Ehrlich HP, Bornstein P (1972) Further characterization of a pro-a2 chain. Biochem Biophys Res Commun 46: 1750–1756
Eilon G, Raisz LG (1978) Comparison of the effects of stimulators and inhibitors of resorption on the release of lysosomal enzymes and radioactive calcium from fetal bone in organ culture. Endocrinology 103: 1969–1972
Eisen AZ (1969) Human skin collagenase: relationship to the pathogenesis of epidermolysis bullosa dystrophica. J Invest Dermatol 52: 449–453
Eisen V (1970) Plasma kinins in synovial exudates. Br J Exp Pathol 51: 322–327
Elders MJ, McNatt ML, Kilgore BS, Hughes ER (1977) Glucocorticoid inhibition of glycosaminogly- can biosynthesis: decrease of protein acceptor. Biochem Biophys Res Commun 77: 557–565
Elders MJ, McNatt ML, Kilgore BS, Hughes ER (1977) Glucocorticoid inhibition of glycosaminogly- can biosynthesis: decrease of protein acceptor. Biochem Biophys Res Commun 77: 557–565
Evans JM, Jeffrey J J, Krane SM (1967) Human collagenase: Identification and characterization of an enzyme from rheumatoid synovium in culture. Science 158: 499–502
Eyre DR, Muir H (1975 a) Type III collagen in synovium. Lancet, 609–610
Eyre DR, Muir H (1975b) Type III collagen: a major constituent of rheumatoid and normal human synovial membrane. Connect Tissue Res 4: 11–16
Eyre DR, Muir H (1975b) Type III collagen: a major constituent of rheumatoid and normal human synovial membrane. Connect Tissue Res 4: 11–16
Eyre DR, Muir H (1977) Quantitative analysis of types I and II collagens in human intervertebral discs at various ages. Biochim Biophys Acta 492: 29–42
Eyre DR, McDevitt CA, Muir H (1975) Experimentally induced osteoarthritis in the dog. Collagen biosynthesis in control and fibrillated articular cartilage. Ann Rheum Dis [Suppl 2]. 34: 138–140
Fahey JV, Newcombe DS (1978) The effect of 7-oxa-13-prostynoic acid on the mechanism of action of bradykinin in human synovial fibroblasts. Prostaglandins 15: 333–342
Farber E (1972) The pathology of transcription and translation. Marcel Dekker, New York
Farber JL, El-Mofty SK (1975) The biochemical pathology of liver cell necrosis. Am J Pathol 81: 237–250
Faris B, Salcedo LL, Cook V, Johnson L, Foster J A, Franszblau C (1976) The synthesis of connective tissue protein in smooth muscle cells. Biochim Biophys Acta 418: 93–103
Farnsworth PN, Burke P, Dotto ME, Cinotti AA (1977) Ultrastructural abnomalities in a Marfan- syndrome lens. Arch Ophthalmol 95: 1601–1611
Feinman L, Lieber CS (1972) Hepatic collagen metabolism: Effect of alcohol-consumption in rats and baboons. Science 176: 795
Fietzek PP, Kühn K (1976) The primary structure of collagen. Int Rev Connect Tissue Res 7: 1–60
Figura K von, Kresse H (1972) The Sanfilippo B corrective factor. N-acetylglucosaminidase. Biochem Biophys Res Commun 48: 262–269
Finch RA, Parker CL, Walton ST (1978) The lack of an inhibitory effect of hyaluronate on chondro-genesis in chick limb-bud mesoderm cells grown in culture. Cell Differ 7: 283–293
Fink CW, Ferguson JL, Smiley JD (1967) Effect of hypothyroidism on collagen metabolism. J Lab Clin Med 69: 950–959
Fink CW, Ferguson JL, Smiley JD (1967) Effect of hypothyroidism on collagen metabolism. J Lab Clin Med 69: 950–959
Fischer GM, Swain ML (1978) In vivo effects of sex hormones on aortic elastin and collagen dynamics in castrated and intact male rats. Endocrinology 102: 92–97
Fischer JA, Binswanger U (1978) Parathyreoidea. Parathormon, Calcitonin und D-Vitamine. In: Labhart A (Hrsg) Klinik der inneren Sekretion. Springer, Berlin Heidelberg New York, S 805–918
Fisher LE, Koch G (1976) Inhibition of protein synthesis by heia cell surface peptides. Biochem Biophys Res Commun 72: 1229–1236
Fitzhugh OG, Nelson A A (1948) Liver tumors in rats fed thiourea of thioacetamide. Science 108: 626–628
Fleischmajer R (1977) The pathophysiology of scleroderma. Int J Dermatol 16: 310–318
Fleischmajer R, Gay S, Meigel WN, Perlish J (1978) Collagen in the cellular and fibrotic stages of scleroderma. Arthritis Rheum 21: 418–428
Fleischmajer R, Perlish J (1972) Glycosaminoglycans in skleroderma and skleroedema. J Invest Dermatol 58: 129–132
Fluharty AL, Stevens RL, Sanders DL, Kihara H (1974) Arylsulfatase B deficiency in Maroteaux- Lamy syndrome cultured fibroblasts. Biochem Biophys Res Commun 59: 455–461
Forbes JC (1939) Studies on the prevention of liver cirrhosis by the subcutaneous injections of xanthine containing preparations. J Pharmacol Exp Ther 65: 287–293
Forbes JC (1939) Studies on the prevention of liver cirrhosis by the subcutaneous injections of xanthine containing preparations. J Pharmacol Exp Ther 65: 287–293
Forbes JC (1939) Studies on the prevention of liver cirrhosis by the subcutaneous injections of xanthine containing preparations. J Pharmacol Exp Ther 65: 287–293
Francis G, John R, Thomas J (1973) Biosynthetic pathway of desmosines in elastin. Biochem J 136: 45–55
Francis G, Donnelly PV, DiFerrante N (1976) Abnormally soluble collagen produced in fibroblasts cultures. Experientia 32: 691–693
Franklin EC ( 1976 a) Recent progress in amyloid. In: Beers RS, Basset E (eds) The role of immunological factors in infectious, allergic and autoimmune processes. Raven Press, New York, pp 163–174
Franklin EC (1976 b) Some properties of antisera to human amyloid A-protein (SAA): inhibiton of precipitation by complexing of SAA to albumin. J Exp Med 144:1679–1682
Fransson L-A (1977) Structure of self-associating heparan sulfate species. Ups J Med Sei 82: 130
Franzblau C (1971) Elastin. In: Florkin M, Stotz EH (eds) Comprehensive chemistry, vol 26 C. Elsevier, Amsterdam, pp 659–712
Froesch ER, Zapf J, Andhya TK, Ben-Porath E, Segen BJ, Gibson KD (1976) Non suppressive insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage. Proc Natl Acad Sei USA 73: 2904–2908
Froesch ER, Zapf J, Meuli C, Mäder M, Waldvogel M, Kaufmann U, Morell B (1975) Biological properties of NSILA-S. In: Levine R, Luft R (eds) Advances metabolic disorders, vol 8. Academic Press, New York, pp 211–239
Fromme HG, Buddecke E, Figura K von, Kresse H (1976) Localisation of sulfated glycosaminoglycans within cell nuclei by high resolution autoradiography. Exp Cell Res 102: 445–449
Fryklund L, Sievertsson H (1978) Primary structure of somatomedin B: A growth hormone-dependent serum factor with protease inhibiting activity. FEBS Lett 87: 55–60
Fryklund L, Uthne K, Sievertsson H (1974) Identification of two somatomedin-A active polypeptides and in vivo effects of a somatomedin-A concentrate. Biochem Biophys Res Commun 61: 957–962
Fujii K, Tanzer ML (1977) Osteogenesis imperfecta: biochemical studies of bone collagen. Clin Orthop 124: 271–277
Fukae M, Mechanic GL, Adamy L, Schwartz ER (1975) Chromatographically different type II collagen from human, normal and osteoarthritic cartilage. Biochem Biophys Res Commun 67: 1575–1580
Funatsu K (1976) Ultrastructural observation of AMPS in experimental hepatic fibrosis and suppression of hepatic fibrosis by crude papain. Acta Hepatol Jpn 17: 141–157
Funatsu K, Ishii H, Shigety Y, Morita A, Tsuchiya M (1978) D-Galactosamine induced hepatic cirrhosis: its ultrastructural and biochemical studies in rat. Acta Hepatograstroenterol (Sttuttg) 25: 97–104
Furthmayer H, Timpl R (1976) Immunochemistry of collagen and procollagens. Int Rev Connect Tissue Res 7: 61–99
Furukawa K, Bhavanandan VP (1982) Influence of glycosaminoglycans on endogenous DNA synthesis in isolated normal and cancer cell nuclei. Biochim Biophys Acta 697: 344–352
Furukawa K, Terayama H (1977) Isolation and identification of glycosaminoglycans associated with purified nuclei from rat liver. Biochem Biophys Acta 499: 278–289
Gabbiani G, Majno G, Ryan GB (1973) The fibroblast as a contractile cell: the myo-fibroblast. In: Kulonen E, Pakkarainen J (eds) Biology of the fibroblast. Academic Press, New York London, pp 139–154
Galambos JT (1966) Acid mucopolysaccharides and cirrhosis of the liver. Gastroenterology 51: 65–74
Galambos JT (1975) Classification of cirrhosis. Am J Gastroenterol 64: 437–451
Galambos JT, Shapira R (1973) Natural history of alcoholic hepatitis. IV. Glycosaminoglycuronans and a collagen in the hepatic connective tissue. J Clin Invest 52: 2952–2962
Gallopp PM, Blumenfeld 00, Seifter S (1972) Structure and metabolism of connective tissue proteins. Annu Rev Biochem 41: 617–672
Gallopp PM, Blumenfeld 00, Seifter S (1972) Structure and metabolism of connective tissue proteins. Annu Rev Biochem 41: 617–672
Gauss V, Wiestner M, Krieg Th, Müller PK (1977) Collagen synthesis: an example to study regulation of gene expression in eukaryotes. Hoppe Seylers Z Physiol Chem 358: 1203–1024
Gauss V, Wiestner M, Krieg Th, Müller PK (1977) Collagen synthesis: an example to study regulation of gene expression in eukaryotes. Hoppe Seylers Z Physiol Chem 358: 1203–1024
Gay S, Fietzek PP, Remberger K, Eder M, Kühn K (1975a) Liver cirrhosis: immunofluorescence and biochemical studies demonstrate two types of collagen. Klin Wochenschr 53: 205–208
Gay S, Inouye T, Minick OT, Kent G, Popper H (1976a) Basement membrane formation in experimental hepatic injury. Gastroenterology 71: 907
Gay S, Martin GR, Müller PK, Timpl R, Kühn K (1976b) Simultaneous synthesis of Type I and Type III collagen by fibroblasts in culture. Proc Natl Acad Sei USA 73: 4037–4040
Gay S, Miller EJ (1978) Collagen in the physiology and pathology of connective tissue. Fischer, Stuttgart New York
Gay S, Müller PK, Lemmen C, Remberger K, Matzen K, Kühn K (1976c) Immunohistological study on collagen in cartilage bone metamorphosis and degenerative osteoarthritis. Klin Wochenschr 54: 969–976
Gay S, Müller PK, Meigel WN, Kühn K (1976d) Polymorphie des Kollagens. Neue Aspekte zur Struktur und Funktion des Bindegewebes. Hautarzt 27: 196–205
Gibbs DA, Merril EW, Smith KA, Balazs EA (1968) Rheology of hyaluronic acid. Biopolymers 6: 777–791
Ginsberg L, Ferrante DT di, Caskey CT, Ferrante N di (1977) Glucosamine-6-S04 sulfatase dificiency: a new mucopolysaccharidosis. Clin Res 25:471 A
Glenner GG, Cuatrecasas P, Isersky C, Bladon HA, Eanes ED (1969) Physical and chemical properties of amyloid fibers: II. Isolation of a unique protein constituting the major component of human splenic amyloid fibril concentrates. J Histochem Cytochem 17: 769–777
Glenner GG, Page GL (1976) Amyloidosis and amyloidogenesis. Int Rev Exp Pathol 15: 1–92
Glenner GG, Terry W, Harada M, Isersky C, Page D (1971) Amyloid fibril proteins; proof of homology with immunoglobuline light chains by sequence analysis. Science 172: 1150–1151
Gore I, Seiwert VI (1952) Dissecting aneurysm of the aorta connective tissue and its changes with age. AMA Arch Pathol 53: 121–141
Gorevic PD, Rosenthal CJ, Franklin GC (1976) Amyloid-related serum component ( SAA) studies in acute infections medullary thyroid carcinoma and post-surgery. Clin Immunol Immunopathol 6: 83–93
Gospodarowicz D (1975) Purification of a fibroblast growth factor from bovine pitnitary. J Biol Chem 250: 2515–2520
Gospodarowicz D, Moran JS (1976) Growth factors in mammalian cell cultures. Annu Rev Biochem 45: 531–553
Gottschalk A (1972) Glycoproteins, their composition, structure and function. B.B.A. Library, vol a + b. Elsevier, Amsterdam London New York
Grant ME, Jackson DS (1976) The biosynthesis of procollagen. Assays Biochem 12: 77–113
Grant ME, Jackson DS (1976) The biosynthesis of procollagen. Assays Biochem 12: 77–113
Grant ME, Prockop DJ (1972b) The biosynthesis of collagen. N Engl J Med 286: 242–249
Grant ME, Prockop DJ (1972c) The biosynthesis of collagen. N Engl J Med 286: 291–300
Gray WR, Sandberg LB, Forster JA (1973) Molecular model for elastin structure and function. Nature 246: 461 - 466
Greaves MW, Sondergaard J, McDonald-Gibson W (1971) Recovery of prostaglandins in human cutaneous inflammation. Br Med J 2: 258–260
Gregoire PE, Dictus-Vermeulen C, Ameryckx JP (1972) Sulfate de dermatane et sulfat de héparitine du foi de bœuf. Biochim Biophys Acta 279: 102–117
Greiling H (1964) Untersuchungen über die Isoenzyme der Lactat-Dehydrogenase in der Synovialflüs-sigkeit. Klin Wochenschr 42: 427–4131
Greiling H (1972) Zur Biochemie der rheumatoiden Arthritis. Z Rheumaforsch [Suppl 2], 31: 26–37
Greiling H (1973) Studies on lysosomal proteoglycan degradation. In: Connective tissue and ageing, vol 1. Intern Congress Series no 264, Excerpta Medica, Amsterdam, pp 168–170
Greiling H (1976) Recent studies on the clinical biochemistry of chronic forms of polyarthritis. In: Wagenhäuser FJ (ed) Chronic forms of polyarthritis. Huber, Stuttgart, pp 175–189
Greiling H, Baumann G (1973) Age dependent changes of non-sulfated disaccharide groups in the proteoglycans of knee joint cartilage. In: Vogel HG (ed) Connective tissue and ageing. Excerpta Medica, Amsterdam, pp 160–162
Greiling H, Driesch R, Momburg M, Jagdfeld R, Thomas J, Stuhlsatz HW (1976) Zur Altersabhängigkeit der Glykosyltransferasen. In: Platt D (ed) Aiternstheorien. Schattauer, Stuttgart New York, S 205–214
Greiling H, Kisters R, Heindl W, Stuhlsatz HW (1971) Inhibition of the biosynthesis of collagen, proteoglycans and glycoproteins by immunosuppressive and antiinflammatory drugs. In: Müller W, Harwerth H-G, Fehr K (eds) Rheumatoid arthritis. Pathogenetic mechanism and consequences in therapeutic. Academic Press, New York London, pp 683–688
Greiling H, Kisters R, Stuhlsatz HW ( 1970 a)Elimination reaction in amino acid containing hyaluronic acid preparations. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix. Academic Press, London New York, pp 759–762
Greiling H, Kleesiek K (1978) Die Synoviaanalyse und ihre differentialdiagnostische Bedeutung bei chronischen Gelenkerkrankungen. Internistische Welt 4: 121–130
Greiling H, Gressner AM, Stuhlsatz HW (1981) Zum Stoffwechsel und zur Pathobiochemie der Proteoglykane. Verh Anat Ges 75: 115–124
Greiling H, Gressner AM, Stuhlsatz HW (1981) Zum Stoffwechsel und zur Pathobiochemie der Proteoglykane. Verh Anat Ges 75: 115–124
Greiling H, Stuhlsatz HW, Kisters R (1969) Struktur und Stoffwechsel von Keratansulfat-Peptiden. Hoppe Seylers Z Physiol Chem 350: 669
Greiling H, Stuhlsatz HW, Kisters R (1970b) Structur and metabolism of proteokeratan sulphate. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol II. Academic Press, London New York, pp 873–877
Greiling H, Stuhlsatz HW, Kisters R (1967) Struktur und Stoffwechsel von Glykosaminoglykan- Proteinen. III. Die Chondroitin-Peptide der Rinder-Cornea. Hoppe Seylers Z Physiol Chem 348: 970–978
Gressner AM, Greiling H (1977) The influence of glycosaminoglycans on the synthesis of polyphenyl-alanine by rat liver ribosomes. Hoppe Seylers Z Physiol Chem 358: 69–78
Gressner AM, Greiling H, Pazen H (1978) Die Biosynthese der Glykosaminoglykane in der akut chronisch geschädigten Leber. In: Lang H, Rick W, Roka L (Hrsg) Aktuelle Probleme der Pathobiochemie. Springer, Berlin Heidelberg New York, pp 31–53
Gressner AM, Köster-Eiserfunke W, Greiling H (1980) Binding of native rat liver proteoglycans to homologous ribosomal subunits. Abstract VII Europ. Symp. Connect. Tissue Res. (1980) p 140–141
Griffiths R, Tuball N, Thomas J (1976) Effect of induced elevated plasma levels of homocystine and methionine in rats on collagen and elastin structures. Connect Tissue Res 4: 101–106
Gross J (1976) Aspects of the animal collagenases. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York London, pp 275–317
Gross J, Kirk D (1958) The heat precipitation of collagen from neutral salt solutions: Some rate-regulating factors. J Biol Chem 233: 355–360
Gross J, Lapiere ChM (1962) Collagenolytic activita in amphibian tissues: A tissue culture assay. Proc Natl Acad Sei USA 48: 1014–1022
Gupta DN (1955) Production of cancer of the bile ducts with thioacetamide. Nature 175: 257
Gupta DN (1956) Nodular cirrhosis and metastasing tumors produced in the liver of rats by prolonged feeding with thioacetamide. J Pathol Bacteriol 72: 415–426
Häkkinen H-M, Franssila K, Kulonen E (1975) Effect of long-term administration of ethanol to the rat. Lipids, collagen and other proteins, and mallory bodies in the liver. Scand J Clin Lab Invest 35: 753–765
Hall CW, Cantz M, Neufeld EF (1973) A glucuronidase deficiency mucopolysaccharidosis. Studies in cultured fibroblasts. Arch Biochem Biophys 155: 32–38
Hall DA (1976) The ageing of connective tissue. Academic Press, London New York San Francisco
Hall DA, Czerkawski JW (1959) The purification of the proteolytic component of elastase. Biochem J 73: 356–361
Hall DA, Czerkawski JW (1961) The reaction between elastase and elastic tissue. 4. Soluble elastins. Biochem J 80: 123–128
Hall DA, Wilkinson JE (1963) Elastase and thrombogenesis. Nature 197: 454–455
Hall K (1971) Effect of intravenous administration of human growth hormone on sulphation factor activity in serum of hypopituitary subjects. Acta Endocrinol (Kbh) 66: 491–497
Hall K, Olin P (1972) Sulphation factor activity and growth rate during longterm treatment of patients with pituitary dwarfism with human growth hormone. Acta Endocrinol (Kbh) 69: 417–433
Hall K, Uthne K (1971) Some biological properties of purified sulfation factor ( SF) from human plasma. Acta Med Scand 190: 137–143
Hall K, Takano K, Fryklund L, Sievertsson H (1975) Somatomedins. Adv Metab Disord 8: 19–46
Hallahan C, Young D, Munck A (1973) Time course of early events in the action of glucocorticoids on rat thymus cell in vitro. J Biol Chem 248: 2922–2927
Hamberg M, Jonsson CE (1973) Increased synthesis of prostaglandins in the guinea pig following scalding injury. Acta Physiol Scand 87: 240–245
Handley CJ, Brooks PR, Lowther DA (1978) Extracellular matrix metabolism by chondrocytes. VI. Concomitant depression by exogenous levels of proteoglycan of collagen and proteoglycan synthesis by chondrocytes. Biochim Biophys Acta 544: 441–444
Handley CJ, Lowther DA (1977) Extracellular matrix metabolism bei chondrocytes. III. Modulation of proteoglycan synthesis by extracellular levels of proteoglycans in cartilage cells in culture. Biochim Biophys Acta 500: 132–139
Haney A, Peacock EE, Madden JW (1972) Liver regeneration and hepatic collagen deposition in rats with dimethylnitrosamine-induced cirrhosis. Ann Surg 175: 863–869
Hanset R, Ansay M (1967) Dermatosparaxie (peau-déchirée) chez le veau: un défaut général du tissu conjonctif, de nature héréditaire. Ann Med Vet 7: 451–458
Hardingham TE, Muir H (1972) The specific interaction of hyaluronic acid with cartilage proteoglycans. Biochim Biophys Acta 279: 401–405
Hardingham TE, Muir H (1973) Binding of oligosaccharides of hyaluronic acid to proteoglycans. Biochem J 135: 905–908
Hardingham TE, Muir H (1974) Hyaluronic acid in cartilage and proteoglycan aggregation. Biochem J 139: 565–581
Harris ED (1972) A collagenolytic system produced by primary cultures of rheumatoid nodule tissue. J Clin Invest 51: 2973–2976
Harris ED (1978) Role of collagenases in joint destruction. In: Sokoloff L (ed) The joints and synovial fluid, Vol I. Academic Press, New York London, pp 243–272
Harris ED, Farrell ME (1972) Resistance to collagenase: a characteristic of collagen fibrils cross-linked by formaldehyde. Biochim Biophys Acta 278: 133–141
Harris ED, Faulkner CS, Brown FE (1975) Collagenolytic systems in rheumatoid arthritis. Clin Orthop 110: 303–316
Harris ED, Krane SM (1972) An endopeptidase from rheumatoid synovial tissue culture. Biochim Biophys Acta 258: 566–576
Harris ED, Krane SM (1973) Cartilage collagen: substrate in soluble and fibrillar form for rheumatoid collagenase. Trans Assoc Am Physicians 86: 82–94
Harris ED, McCroskery PA (1974) The influence of temperature and fibril stability on degradation of cartilage collagen by rheumatoide synovial collagenase. N Engl J Med 290: 1–6
Harris ED, Sjoerdsma A (1966) Collagen profile in various clinical conditions. Lancet 2: 707–711
Hart GW (1976) Biosynthesis of glycosaminoglycans during corneal development. J Biol Chem 251: 6513–6521
Hart GW, Lennarz WJ (1978) Effects of tunicamycin on the biosynthesis of glycosaminoglycans by embryonic chick cornea. J Biol Chem 253: 5795–5801
Hartmann F, Deicher H (1979) Bindegewebe. In: Siegenthaler W (Hrsg) Klinische Pathophysiologic. Thieme, Stuttgart, S 948–992
Harvey W, Grahame R, Panayi GS (1974) Effects of steroid hormones on human fibroblasts in vitro. Glucocorticoid action on cell growth and collagen synthesis. Ann Rheum Dis 33: 437–441
Harwood R, Grant ME, Jackson DS (1974) Collagen biosynthesis. Characterization of subcellular fractions from embryonic chick fibroblasts and the intracellular localization of protocollagen prolyl and protocollagen lysyl hydroxylases. Biochem J 144: 123–130
Harwood R, Grant ME, Jackson DS (1975) Translation of type I and type II procollagen messengers in a cell-free system derived from wheat germ. FEBS Lett 57: 47–50
Hascall VC, Heinegard D (1974a) Aggregation of cartilage proteoglycans. I. The role of hyaluronic acid. J Biol Chem 249: 4232–4241
Hascall VC, Heinegard D ( 1974 b) Aggregation of cartilage proteoglycans. II. Oligosaccharide competitors of the proteoglycan-hyaluronic acid interaction. J Biol Chem 249: 4242–4249
Hascall VC, Riolo R-L (1972) Characteristics of the protein-keratan sulfate core and of keratan sulfate prepared from bovine nasal cartilage proteoglycan. J Biol Chem 247: 4529–4538
Hascall VC, Sajdera SW (1969) Proteinpolysaccharide complex from bovine nasal cartilage. The function of glycoprotein in the formation of aggregates. J Biol Chem 244: 2384–2396
Hastings SG, Booth NH, Hopwood ML (1968) Influence of sex hormones on mucopolysaccharide synthesis of swine arteries. J Atheroscler Res 8: 29–35
Havemann K, Janoff A (1978) Neutral proteases of human polymorphonuclear leukocytes. Urban Schwarzenberg, Baltimore München
Heersche JNM, Marcus R, Aurbach GD (1974) Calcitonin and the formation of 3‘,5‘-AMP in bone and kidney. Endocrinology 94: 241–247
Heinegard D, Hascall VC (1974a) Aggregation of proteoglycans. III. Characteristics of the proteins isolated from trypsin digests of aggregates. J Biol Chem 249: 4250–4256
Heinrich UE, Schalch DS, Koch JG, Johnson CJ (1978) Non suppressible insulin-like activity (NSILA). II. Regulation of serum concentrations by growth hormone and insulin. J Clin Endocrinol Metab 46: 672–678
Helle O, Ness NN (1972) A heriditabie skin defect in sheep. Acta Fed Scand 13: 443–451
Hennemann DH (1968) Effect of estrogen on in vivo and in vitro collagen biosynthesis and maturation in old and young female guinea pigs. Endocrinology 83: 678–690
Hennemann DH (1970) Inhibition of the effect of D-penicillamine on collagen solubility in skin by 17-estradiol cypionate and the effect of D-penicillamine and 17-estradiol on the abnormalities in rat bone produced by a low calcium diet. Endocrinology 87: 456–464
Hennemann DH (1971) Effect of estradiol-17 on collagen biosynthesis, degradation and reutilization in vivo. Biochem Biophys Res Commun 44: 326–332
Henson PM (1971) The immunologic release of constituents from neutrophilic leukocytes. J Immunol 107: 1535–1546
Herbert CM, Jayson MIV, Bailey AJ (1973) Joint capsule collagen in osteoarthrosis. Ann Rheum Dis 32: 510–514
Higgs GA, Vane JR, Hart FD, Wojtulewski JA (1974) Effects of anti-inflammatory drugs on prostaglandins in rheumatoid arthritis. In: Robinson HJ, Vane JR (eds) Prostaglandinsynthetase inhibitors. Raven Press, New York, pp 165–174
Hintz RL, Clemmons DR, Underwood L (1972) Competitive binding of somatomedin to the insulin receptors of adipocytes, chondrocytes and liver membranes. Proc Natl Acad Sei USA 69: 2351–2353
Hintz RL, Liu F, Rinderknecht E (1980) Somatomidin-C shares the carboxy-terminal antigenic determinants with insulin-like growth factor I. J Clin Endocrinol Metab 51: 672–673
Hirayama C (1974) Hepatic fibrosis: biochemical considerations. In: Schaffner F, Sherlock S, Leevy CM (eds) The liver and its diseases. Thieme, Stuttgart, pp 273–282
Hjertquist SO, Lemperg R (1972) Identification an concentration of the glycosaminoglycans in human articular cartilage in relation to age and osteoarthritis. Calcif Tissue Res 10: 223–237
Höök M, Lindahl U, Hallen A, Bäckström G (1975) Biosynthesis of heparin. J Biol Chem 250: 6065–6071
Hörlein D, McPherson J, Swee Han Goh, Bornstein P (1981) Regulation of protein synthesis: translatinal control by procollagen-derived fragments. Proc Natl Acad Sei USA 78: 6163–6167
Hörmann H, Jilek F (1977) Funktionelle Reaktionen eines Oberflächenproteins von Fibroblasten. Wien Klin Wochenschr 89: 728–729
Hörmann H, Kühn K (1977) Das Zusammenspiel von humoralen Faktoren, extrazellulärer Matrix und von Zellen bei der Wundheilung. Fortschr Med 95: 1299–1304
Holtrop ME, King G, Raisz LG (1978) Factors influencing osteoclast activity as measured by ultra structural morphometry. In: Copp DH, Talmage RV (eds) Endocrinology of calcium metabolism. Excerpta Medica, Amsterdam, pp 91–93
Hong S-CL, Polsky-Cynkin R, Levine L (1976) Stimulation of prostaglandin biosynthesis by vasoactive substances in methylcholanthrene-transformed mouse BALB/3T3. J Biol Chem 251: 776–780
Honig S, Hoffstein S, Weissmann G (1978) Leukocyte lysosomes and inflammation: the example of arthritis. In: Ioachim HL (ed) Pathobiology annual 1978. Raven Press, New York, pp 315–331
Hopwood JJ, Robinson HC (1974) The structure and composition of keratan sulphate. Biochem J 141: 517 - 526
Hornebeck W, Robert L (1977) Elastase like enzymes in aortas and human breast carcinomas: quantitative variations with age and pathology. In: Sandberg LB, Gray WR, Franzblau C (eds) Elastin and elastic tissue. Plenum Press, New York London, pp 145–162
Horwitz AL, Hance AJ, Crystal RG (1977) Granulocyte collagenase: selective digestion of type I over type III collagen. Proc Natl Acad Sei USA 74: 847–901
Houck JC (1973) General introduction to chalone concept. Natl Can Inst Monogr 38: 1–9
Howard DJ, Read AE, Bailey AJ (1975) Characterization of the collagen of normal and cirrhotic human liver. Gut 16: 827
Hradec J, Dusek Z (1978) All factors required for protein synthesis are retained on heparin bound to sepharose. Biochem J 172: 1–7
Hradec J, Kriz O (1978) Heparin-sepharose 4B at low temperatures retains ribosomes. Biochem J 173: 349–352
Hruban Z, Rüssel RM, Boyer JL, Glagov S, Bagheri SA (1974) Ultra structural changes in livers of two patients with hypervitaminosis A. Am J Pathol 76: 451–461
Huang D (1974) Effect of extracellular chondroitin sulfate on cultured chondrocytes. J Cell Biol 62: 881–886
Hufer WE (1973) Degradation of chondromucoprotein by macrophage enzymes. Lab Invest 29: 304–309
Hultin T, Näslund PH (1975) Effects of anions on the structure and functions of mammalian ribosomes. Biochim Biophys Acta 402: 199–205
Humbel RA, Rinderknecht E (1978) From NSILA to IGF (1963-1977). In: International Symposium on somatomedins and growth. Milano (Abstr), p 18
Hunder GG, McDuffie FC, Mullen BJ (1977) Activation of complement components C3 and factor B in synovial fluids. J Lab Clin Med 89: 160–171
Husby G (1975) Amyloidosis in rheumatoid arthritis. Ann Clin Res 7: 154–167
Husby G, Natvig JB (1974) A serum component related to non-immunoglobulin amyloid protein AS, a possible precursor of the fibrils. J Clin Invest 53: 1054–1061
Husby G, Sletten K, Michaelsen TE, Natvig JB (1972) Antigenic and chemical characterization of non-immunoglobulin amyloid proteins. Scand J Immunol 1: 393–400
Husby G, Sletten K, Michaelsen TE, Natvig JB (1973) Amyloid fibril protein subunit, protein AS: distribution in tissue and serum in different clinical types of amyloidosis including that associated with myelomatosis and Waldenstrom‘s macroglobulinaemie. Scand J Immunol 2: 395–404
Husby G, Natvig JB, Sletten K, Nordstoga K, Anders RS (1975) An experimental model in mink for studying the relation between amyloid fibril protein AA and the related serum protein SAA. Scand J Immunol 4: 811–816
Hutterer F (1966) Degradation of mucopolysaccharides by hepatic lysosomes. Biochim Biophys Acta 115: 312–317
Hutterer F, Bacchin P (1968) Mucopolysaccharides in normal and cirrhotic liver in man. Fed Proc 27: 412
Hutterer F, Eisenstadt M, Rubin E (1970) Turnover of hepatic collagen in reversible and irreversible fibrosis. Experientia 26: 244–245
Hutterer F, Rubin E (1975) Mucopolysaccharides in reversible and irreversible experimental hepatic fibrosis. In: Popper H, Becker K (eds) Collagen metabolism in the liver. Stratton Intercontinental Medical Book, New York, pp 53–56
Hutterer F, Rubin E, Singer EJ, Popper H (1959) Alkali-soluble and insoluble collagen in infant adult and cirrhotic livers. Proc Soc Exp Biol Med 102: 534–536
Hutton J J, Udenfriend S (1966) Soluble collagen proline hydroxylase and its substrates in several animal tissues. Proc Natl Acad Sci USA. 56: 198–202
Ignarro LJ (1974) Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3,5-guanosine monophosphate. J Immunol 112: 210–214
Inerot SI, Heinegard D, Audell L, Olsson SE (1978) Articular cartilage proteoglycans in aging and osteoarthritis. Biochem J 169: 143–156
Ishikawa H (1974) Glycosaminoglycans of the skin and urine in patients with progressive scleroderma. In: Otake Y (ed) Biochemistry and pathology of connective tissue. Thieme, Stuttgart, pp 97–110
Ishikawa H, Horiuchi R (1975) Initial change of glycosaminoglycans in systemic scleroderma. Dermatologica 150: 334–354
Ishikawa H, Saito Y, Yamakage A, Kitabatake M (1978) Scleroderma-inducing glycosaminoglycans in the urine of patients with systemic scleroderma. Dermatologica 156: 193–204
Ishikawa H, Suzuki S, Horiuchi R, Sato H (1975) An approach to the experimental scleroderma, using urinary glycosaminoglycans from patients with systemic scleroderma. Acta Derm Venerol (Stockh) 55: 97–107
Iverius P-H (1972) The interaction between human plasma lipoprotein and connective tissue glycosaminoglycans. J Biol Chem 247: 2607–2613
Iverius P-H, Ostlund-Lindquist AM (1976) Lipoprotein lipase from bovine milk, J Biol Chem 251: 7791–7795
Jackson DS, Cleary EG (1967) The determination of collagen and elastin. Methods Biochem Anal 15: 25–76
Jackson SH (1973) The reaction of homocysteine with aldehyde: An explanation of the collagen defects in homocystinuria. Clin Chim Acta 45: 215–217
Janoff A (1975) At least three human neutrophil lysosomal proteases are copable of degrading joint connective tissues. NY Acad Sci 256: 402
Jansson L, Lindahl U (1970) Evidence for the existence of a multichain proteoglycan of heparan sulphate. Biochem J 117: 699–702
Jaques LB (1977) Determination of heparin and related sulfated mucopolysaccharides. In: Glick H (ed) Methods of biochemical analysis, vol 24. Wiley Sons, New York London Sydney Toronto, pp 203–312
Jensen CE, Koefoed J (1954) Flow elasticity of hyaluronate solutions. J Colloid Sei 9: 460–465
Jilek F, Hörmann H (1978) Cold-insoluble globulin (fibronectin). IV. Affinity to soluble collagen of various types. Hoppe Seylers Z Physiol Chem 359: 247–250
Jimenez SA, Dehrn P, Prockop DJ (1971) Further evidence for a transport form of collagen. Its extrusion and extracellular conversion to a-chains in embryonic tendon. FEBS Lett 17: 245–248
John R, Thomas J (1972) Chemical compositions of elastins isolated from aortas and pulmonary tissues of humans of different ages. Biochem J 127: 261–269
Johnson PM, Husby G, Natvig JB, Anders RF, Linder E (1977) Identification in human placentae of antigenic activity related to the amyloid serum protein SAA. Scand J Immunol 6: 319–325
Johnson RL, Ziff M (1976) Lymphokine stimulation of collagen accumulation. J Clin Invest 58: 240–252
Johnson U, Ohlsson K, Olsson K, Olsson I (1976) Effects of granulocyte neutral proteases on complement components. Scand J Immunol 5: 421–426
Johnston RB Jr, Keele BB, Misra HP, Webb LS, Lehmeyer JE, Rajagopalan KV (1975) Superoxide anion generation and phagocytic bactericidal activity. In: Bellantini JA, Dayton DH (eds) The phagocytic cell in hort resistance. Raven Press, New York, pp 61–75
Jones CR, Bergman MW, Kittner PJ, Pigman W (1964) Urinary hydroxyproline excretion in Marfan’s syndrome as compered with aged matched controls. Proc Soc Exp Biol Med 116: 931–933
Jorke D, Reinhardt M (1977) Epidemiology of chronic liver diseases. Acta Hepato-gastroenterol (Stuttg) 24: 220–225
Jorpes JE, Gardell S (1948) On heparin monosulfuric acid. J Biol Chem 176: 267–276
Kamegaya K, Sambe K (1975) Some aspects of collagen fiber formation and degradation in experi¬mental hepatic fibrosis. In: Popper H, Becker K (eds) Collagen metabolism in the liver. Stratton Intercontinental Medical Book, New York, pp 100–113
Kaneko M, Greiling H (1973) Hemmung des Sulfatstoffwechsels und der Phosphoadenylylsulfat: Chondroitinsulfat-Sulfotransferase durch ein Glykosaminoglykanpolysulfat. Arzneim Forsch 23: 737
Kang AH, Trelstad RL (1973) A collagen defect in homoeystinuria. J Clin Invest 52: 2571–2578
Kao K-YT, Hitt WE, McGavack TH (1965) Connective tissue. XIII. Effect of estradiol benzoate upon collagen synthesis by sponge biopsy connective tissue. Proc Soc Exp Biol Med 119: 364–367
Kaplan D, Meyer K (1959) Ageing of human cartilage. Nature 183: 1267–1268
Kaplan D, Meyer K (1960) Mucopolysaccharides of aorta at various ages. Proc Soc Exp Biol Med 105: 78–81
Karzel K, Domenjoz R (1969) The influence of anti-inflammatory drugs on mucopolysaccharide metabolism in relation to cell multiplication, protein synthesis and cell respiration of fibroblasts cultured in vivo. In: Bertelli A, Houck JC (eds) Inflammation biochemistry and drug interaction. Excerpta Medica, Amsterdam, pp 102–108
Katz FH, Kappas A (1968) Influence of estradiol and estriol on urinary excretion of hydroxyproline in man. J Lab Clin Med 71: 65–74
Katz WA, Schubert M (1970) The interaction of monosodium urate with connective tissue components. J Clin Invest 49: 1783–1789
Kawasaki T, Yamashina I (1972) Isolation and characterization of glycopeptides from rat liver nuclear membrane. J Biochem (Tokyo) 72: 1517–1525
Kefalides NA (1971) Chemical properties of basement membranes. Int Rev Exp Pathol 10: 1–39
Kefalides NA (1973) Structure and biosynthesis of basement membranes. Int Rev Connect Tissue Res 6: 63–104
Kefalides NA (1975) Basement membranes. Structural and biosynthetic considerations. J Invest Dermatol 65: 85–92
Kefalides NA (1978) Biology and chemistry of basement membranes. Academic Press, New York London
Keiser H, Greenwald RA, Feinstein G, Janoff A (1976) Degradation of cartilage proteoglycans by human leukocyte granula neutral proteases. A model of joint injury. II. Degradation of isolated bovine nasal cartilage proteoglycans. J Clin Invest 57: 625–632
Keller R, Stein Th, Stuhlsatz HW, Greiling H, Ohst E, Müller E, Scharf HD (1981) Studies on the characterization of the linkage-region between polysaccharide chain and core protein in bovine corneal proteokeratan sulfate. Hoppe-Seylers Z Physiol Chem 362: 327–336
Keller R, Driesch R, Stein Th, Momburg M, Stuhlsatz HW, Greiling H, Franke H (1983) Biosynthesis of proteokeratan sulfate in the bovine cornea. Hoppe-Seylers Z Physiol Chem (im Druck)
Keller R, Stein Th, Weber W, Kehrer Th, Stuhlsatz HW, Greiling H, Keyserlingk D Graf v (1983) Biosynthesis of proteokeratan sulfate in the bovine cornea. Hoppe-Seylers Z Physiol Chem (im Druck )
Kempson GE, Muir H, Swanson SAV, Freeman MAR (1970) Correlations between stiffness and the chemical constituents of cartilage on the human femoral head. Biochim Biophys Acta 215: 70–77
Kempson GE, Muir H, Pollard C, Tuke M (1973) The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans. Biochim Biophys Acta 297: 456–472
Kempson GE, Spivey CJ, Swanson SAV, Freeman MAR (1971) Patterns of cartilage stiffness on normal and degenerate human femoral heads. J Biomech 4: 597–609
Kenny AD (1976) Vitamin D metabolism: physiological regulation in egg-laying Japanese qail. Am J Physiol 230: 1609–1615
Kent G, Fels IG, Dubin A, Popper H (1959) Collagen content based on hydroxyproline determinations in human and rat livers: its relation to morphologically demonstrable reticulum and collagen fibers. Lab Invest 8: 48–56
Kent G, Gay S, Inouye T, Bahu R, Minick OT, Popper H (1976) Vitamin A-containing lipocytes and formation of type III collagen in liver injury. Proc Natl Acad Sei USA 73: 3719–3722
Keppler DOR (1975) Pathogenesis and mechanisms of liver cell necrosis. MTP Press, Lancester
Keret R, Schimpff RM, Girard F (1976) The inhibitory effect of hydrocortisone on the chicken embryo cartilage somatomedin assay. Horm Res 7: 254–259
Kershenobich D, Fierro FJ, Rojkind M (1970) The relationship between the free pool of proline and collagen content in human liver cirrhosis. J Clin Invest 49: 2246–2249
Kerwar SS, Kohn LD, Lapiere CN, Weissbach H (1972) In vitro synthesis of procollagen on polysomes. Proc Natl Acad Sei USA 69: 2727–2731
Keshgegeian A, Glick MC (1973) Glycoproteins associated with nuclei of cells before and after transformation by a ribonucleic acid virus. Biochemistry 12: 1221–1226
Keski-Oja J (1976) Polymerization of a major surface-associated glycoprotein, fibronectin, in cultured fibroblasts. FEBS Lett 71: 325–329
Kimura JH, Hardingham TE, Hascall VC, Solursh M (1978) The effect of oligosaccharides of hyaluro- nate on the aggregation of newly synthesised cartilage proteoglycans. In: International Colloquium of CNRS, vol 287, Creteil, p 26
King JS, Fielden ML, Boyce WH (1962) Acid mucopolysaccharides in normal urine. Clin Chim Acta 7: 316–321
Kitzis A, Defer N, Dastugue B, Sabatier MN, Krüh J (1976) Effect of heparin on chromatin. FEBS Lett 66: 336–339
Kivirikko KI (1974) Biosynthesis of collagen. In: Fricke R, Hartmann F (eds) Connective tissues biochemistry and pathophysiology. Springer, Berlin Heidelberg New York
Kivirikko KI, Koivusalo M, Laitinen O, Liesmaa M (1963) Effect of thyroxine on the hydroxyproline in rat urine and skin. Acta Physiol Scand 57: 462–467
Kivirikko KI, Laitinen O (1965) Urinary 14C-hydroxyproline in thyroxine treated rats after the administration of 14C-proline. Acta Chem Scand 19: 1781
Kivirikko KI, Laitinen O, Aer J, Halma J (1965) Studies with 14C-proline on the action of cortisone on the metabolism of collagen in the rat. Biochem Pharmacol 14: 1445–1451
Kivirikko KI, Laitinen O, Aer J, Halme J (1967) Metabolism of collagen in experimental hyperthyroidism and hypothyeroidism in the rat. Endocrinology 80: 1051–1061
Kivirikko KI, Prockop DJ (1967) Enzymatic hydroxylation of proline and lysine in proteocollagen. Proc Natl Acad Sei USA 57: 782–789
Kivirikko KI, Ristelli L (1976) Biosynthesis of collagen and its alterations in pathological states. Med Biol 54: 159–186
Kjellén L, Oldberg A, Rubin K, Höök M (1977) Binding of heparin and heparansulphate to rat liver cells. Biochem Biophys Res Commun 74: 126–133
Kleesiek K, Müller K-H, Royé Ch, Greiling H (1980) Thrijodthyronin und reverse Trijodthyronin in der Synovialflüssigkeit. Einfluß der Trijodthyronin-Isomere auf den Stoffwechsel von Synoviafibroblasten. Verh Dtsch Ges Rheumatol 6: 402–405
Kleesiek K (1980) Gelenkerkrankungen. Klinisch-chemische und pathobiochemische Befunde zur Differentialdiagnose der Gelenkerkrankung. Med Welt 13: 1609–1617
Kleesiek K (1981) Zur Analytik und Pathobiochemie des synovialen Systems. Habilitationsschrift Rheinisch-Westfälische Technische Hochschule, Aachen
Kleesiek K, Greiling H (1982) The effect of anti-inflammatory agents on the glycosaminoglycan metabolism in cultured human synovial cells. Rheumatol Int 2: 167–174
Kleesiek K, Michels P, Müller K-H, Greiling H (1981) Zur Pathobiochemie der Proteoglykane und des Hyaluronats bei der chronischen Polyarthritis. In: Otte P (Hrsg) Gelenkdestruktion bei Polyarthritis. Steinkopff, Darmstadt, S 57–66
Klein DC, Raisz LG (1971) Role of adenosine 3,5-monophosphate in the hormone regulation of bone resorption: studies with cultured fetal bone. Endocrinology 89: 818–826
Ko SD, Page RC, Narayanan AS (1977) Fibroblast heterogeneity and prostaglandin regulation of subpopulations. Proc Natl Acad Sei USA 74: 3429–3432
Kodicek E (1974) The story of vitamin D from vitamin to hormone. Lancet 1: 325–329
Köster-Eiserfunke W, Gressner AM, Bruhns D, Greiling H (1978) A method for the isolation of proteoglycans from rat liver. Hoppe Seylers Z Physiol Chem 359: 288
Köster-Eiserfunke W, Gressner AM, Greiling H (1979) Binding properties of rat liver proteoglycan to concanavalin A. Hoppe Seylers Z Physiol Chem 360: 306
Koizumi T, Nakamura N, Abe H (1967) Changes in acid mucopolysaccharide in the liver in hepatic fibrosis. Biochim Biophys Acta 148: 749–756
Kojima K, Yamagata T (1971) Glycosaminoglycans and electrokinetic behaviour of rat ascite hepatoma cells. Exp Cell Res 67: 142–146
Kojima J, Nakamura N, Kanatani M, Ohmori K (1975) The glycosaminoglycans in human hepatic cancer. Cancer Res 35: 542–547
Koka M, Nakamoto T (1972) Studies on polyphenylalanine synthesis with a cell-free system of rat lymphosarcoma. Biochim Biophys Acta 262: 381–392
Kondo H, Rabin BS, Rodnan GA (1976) Cuteneous and antigen stimulating lymphokine production by lymphocytes patients with progressive systemic sclerosis (scleroderma). J Clin Invest 58: 1388–1394
Kornfeld R, Kornfeld S (1976) Comparative aspects of glycoprotein structure. Annu Rev Biochem 45: 217–237
Kosher RA, Lash JW, Minor RR (1973) Environmental enhancement of in vitro chondrogenesis: IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein. Dev Biol 35: 210–220
Kraemer PM (1971) Heparan sulfate of cultured cells. II. Acid-soluble and precipitable species of different cell lines. Biochemistry 10: 1445–1451
Kraemer PM (1977) Heparin releases heparan sulfate from the cell surface. Biochem Biophys Res Commun 78: 1334–1340
Kraemer RJ, Coffey DS (1970) The interaction of natural and synthetic polyanions with mammalian nuclei. II. Nuclear swelling. Biochim Biophys Acta 224: 568–578
Krane SM (1974) Joint erosion in rheumatoid arthritis. Arthritis Rheum 17: 306–312
Krane SM, Pinneil SR, Erbe RW (1972) Lysyl-protocollagen hydroxylase deficienca in fibroblasts from siblings with hydroxylysinedeficient collagen. Proc Natl Acad Sei USA 69: 2899–2903
Krawetz SA, Anwar RA (1979) Elastin mRNA isolation and in vitro translation. Fed Proc 38 /3: 300
Kreitzman L, Phelps CF (1967) The testosterone-induced biosynthesis of glycosaminoglycans in chick combs. Biochem J 105: 23
Kresse H (1973) Mucopolysaccharidosis III A (Sanfilippo A disease): deficiency of a heparin sulfa-minidase in skin fibroblasts and leucocytes. Biochem Biophys Res Commun 54: 1111–1118
Kresse H, Neufeld EF (1972) The Sanfilippo A corrective factor, purification and mode of action. J Biol Chem 247: 2164–2170
Kreysel HW, Kraus H, Stuhlsatz HW, Greiling H, Nissen HP, Kimmig J (1977) Zur quantitativen Darstellung (säulenchromatographische Trennung) saurer Mucopolysaccharide im Urin bei der progressiven Sklerodermie. Arch Dermatol Res 259: 11–19
Krieg TH, Aumailley M, Kessler W, Müller WK (1977b) Collagen synthesis in heriditary connective tissue disorders. Hoppe Seylers Z Physiol Chem 358: 1235–1236
Kruse NJ, Rowe DW, Fujimoto WY, Bornstein P (1978) Inhibitory effects of glucocorticoids on collagen synthesis by mouse sponge granulomas and granuloma fibroblasts in culture. Biochim Biophys Acta 540: 101–116
Kruze D, Menninger H, Fehr K, Boni A (1976) Purification and some properties of a neutral protease from human leukocyte granules and its comparison with pancreatic elastase. Biochim Biophys Acta 438: 503–513
Kuehl FA Jr (1973) Prostaglandines, nucleotides cycliques et physiologie cellulaire. In: Prostaglandines 1973. Inserm, Paris, pp 55–80
Kuehl FA Jr (1974) Prostaglandins, cyclic nucleotides and cell function. Prostaglandins 5: 325–340
Kühn K (1978) Einige Beispiele zur Pathobiochemie des Kollagenstoffwechsels. In: Lang H, Rick W, Roka L (Hrsg) Aktuelle Probleme der Pathobiochemie. Springer, Berlin, S 55–69
Kühn K, Holzmann H, Körting GW (1962) Quantitative Bestimmungen der löslichen Kollagenstufen nach Anwendung einiger Bindegewebstherapeutica. Naturwissenschaften 49: 134
Kuettner KE, Soble L, Croxen RL, Marczynska B, Hifi J, Harper E (1977) Tumor cell collagenase and its inhibition by a cartilage derived protease inhibitor. Science 196: 653–654
Kunz J (1975) Pathologie der Arterienwand. VEB Verlag Volk und Gesundheit, Berlin
Kuo SC, Lampen JO (1974) Tunicamycin - An inhibitor of yeast glycoprotein synthesis. Biochem Biophys Res Commun 58: 287–295
Kuo SC, Lampen JO (1976) Tunicamycin inhibition of 3H-glucosamin incorporation into yeast glycoproteins: binding of Tunicamycin and interaction with phospholipids. Arch Biochem Biophys 172: 574–581
Laitinen O (1967) The metabolism of collagen and its hormonal control in the rat. Acta Endocrinol(Kbh.) [Suppl] 120: 52–57
Laitinen O, Uitto J, Iivanainen M, Hannuksela M, Kivirikko KI (1968) Collagen metabolism of the skin in Marfan‘s syndrome. Clin Chim Acta 21: 321–326
Lamberg SI (1979) Stimulatory effect of exogenous hyaluronic acid distinguistes cultures fibroblasts of Marfan‘s disease from centrals. J Invest Dermatol 71: 391–395
Lamberg SI, Dorfman A (1973) Synthesis and degradation of hyaluronic acid in the cultured fibroblasts of Marfan‘s disease. J Clin Invest 52: 2428–2433
Lamy F, Gibson D, Ledoux M, Moreux JC (1977) Chymotrypsinogen D, a new zymogen from porcine pancreas with proelastolytic activity. In: Sandberg LB, Gray WR, Franzblau C (eds) Elastin and elastic tissue. Plenum Press, New York London, pp 165–175
Lancaster G, Goldman H, Scriver PR, Gold RJ, Wong I (1975) Dominantly inherited osteogenesis imperfecta in man: An examination of collagen biosynthesis. Pediatr Res 9: 83–88
Lancker van JL (1976) Molecular and cellular mechanisms in disease, vol 1 and 2. Springer, Berlin Heidelberg New York
Langness U, Behnke A (1971) Collagen metabolites in plasma and urine in osteogenesis imperfecta. Metabolism 20: 456–463
Lapiere ChM, Gross J (1963) Animal collagenase and collagenmetabolism. In: Sognnaes RS (ed) Mechanisms of hard tissue destruction, No 75. American Association Advanced Science Washington, pp 663–675
Lapiere ChM, Nusgens B (1976) Collagen pathology at the molecular level. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York London, pp 377–447
Laurent TC (1964) Solubility of sodium urate in the presence of chondroitin 4-sulphate. Nature 202: 1334
Laurent TC (1970) Structure of hyaluronic acid. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix. Academic Press, New York London, pp 703–732
Layman DL, McGoodwin EB, Martin GR (1971) The nature of collagen synthesized by cultured human fibroblasts. Proc Natl Acad Sei USA 68: 454–458
Layman DL, Sokoloff L, Miller EJ (1972) Collagen synthesis by articular chondrocytes in monolayer culture. Exp Cell Res 73: 107–112
Lazarides EL, Lukens LN, Infante AA (1971) Collagen polysomes: site of hydroxylation of proline residues. J Mol Biol 58:831–846 Lebovitz HE, Eisenbarth GS (1975) Hormonal regulation of cartilage growth and metabolism. Vitam Horm 33: 575–648
Leevy CM, Popper H, Sherlock S (Criteria committee) (1976) Diseases of the liver and bilary tract. Standardization of nomenclature, diagnostic criteria, diagnostic methodology. FOGARTA International Center Proceedings, No 22, DHEW Publication. Government Printing Office, Washington, D.C., pp 76–725
Lelbach WK (1976) Epidemiology of alcoholic liver disease. In: Popper H, Schaffner F (eds) Progress in liver diseases. Grune Stratton, New York San Francisco London, pp 494–515
Lenaers A, Ansay M, Nusgens B, Lapiere ChM (1971) Collagen made of extended a-chains, procollagen, in genetically defective dermatosparaxic calves. Eur J Biochem 23: 533–543
Leroy EC (1972) Connective tissue synthesis by scleroderma skin fibroblasts in cell culture. J Exp Med 135: 1351–1362
Leroy EC (1974) Increased collagen synthesis by scleroderma skin fibroblasts in vitro. A possible defect in the regulation or activation of the scleroderma fibroblast. J Clin Invest 54: 880–889
Lesch R, Keppler D, Reutter W, Rudiger J, Oehlert W, Decker K (1970) Entwicklung einer experimentellen Leberzirrhose durch D-Galactosamin. Histologische, biochemische und autoradiographische Untersuchungen an Ratten. Virchows Arch. [Cell Pathol] 6: 57–71
Lesch R, Reutter W (1975) Liver regeneration after experimental injury. Stratton Intercontinental Medical Book, New York
Letterer E (1968) History and development of amyloid research. In: Manderna E, Ruinen L, Sholten SH, Cohen AS (eds) Amyloidosis. Excerpta Medica, Amsterdam, pp 3–10
Lever WF (1961) Histopathology of the skin, 3rd ed. Lippincott, Philadelphia
Levin M, Pras M, Franklin EC (1973) Immunologic studies of the major non-immunoglobulin protein of amyloid. J Exp Med 138: 373–380
Libaers I, Neufeld EF (1976) Iduronate sulfatase activity in serum, lymphocytes and fibroblasts- simplified diagnosis of the Hunter Syndrome. Pediatr Res 10: 733–736
Lichtenstein JR, Martin GR, Kohn LD, Byers PH, McKusick VA (1973) Defect in conversion of procollagen to collagen in a form of Ehlers-Danlos-syndrome. Science 182: 298–300
Lieber CS, Carli LM de (1976) Animal models of ethanol dependence and liver injury in rats and baboons. Fed Proc 35: 1232–1236
Likar IN, Robinson RW, Likar LJ (1982) Glycosaminoglycans and hormones: mesenchymal response in endocrinopathies. In: Varma RS, Varma R, Warren Pa (eds) Glycosaminoglycans and proteo-glycans in physiological and pathological processes of body systems. Karger, Basel, pp 412–439
Likar LJ, Likar IN, Robinson RW (1965) Levels of acid mucopolysaccharides on the bovine aorta at different stages of the sexual cycle. J Atheroscler Res 5: 388–396
Lindahl U, Höök M (1978) Glycosaminoglycans and their binding to biological macromolecules.Annu Rev Biochem 47: 385–417
Lindahl U, Höök M, Bäckström G, Jacobsson I, Riesenfeld J, Malmström A, Roden L, Feingold DS (1977) Structure and biosynthesis of heparin-like polysaccharides. Fed Proc 36: 19–23
Lindberg KA, Hassett MA, Pinell SR (1976) Inhibition of lysyl-oxidase by homocysteine; a proposed connective tissue defect in homocystinuria. Clin Res 24:265 A
Linder E, Anders RF, Natvig JB (1976) Connective tissue origin of the amyloid related protein SAA. J Exp Med 144: 1336–1346
Linke RP, Sipe JD, Pollock PS, Ignaczak TF, Glenner GG (1975) Isolation of low molecular weight serum component antigenically related to an amyloid fibril protein of unknown origin. Proc Natl Acad Sei USA 72: 1473–1476
Liotta LA, Vembu D, Kleinman HK, Martin GR, Boone CW (1978) Collagen required for proliferation of cultured connective tissue cells but not their transformed counterparts. Nature 272: 622–624
Lowther OA, Gillard GC (1976) Carrageenien - induce arthritis. I. The effect of intraarticular carrageenin on the chemica composition of articular cartilage. Arthritis Rheum 19: 769–776
Lüben RA, Cohn DV (1976) Effects of parathormone and calcitonin on citrate and hyaluronate metabolism in cultured bone. Endocrinology 98: 413–419
Lüben RA, Wong GL, Cohn DV (1976) Biochemical characterization with parathormone and calcitonin of isolated bone cells: provisional identification of osteoclasts and osteoblasts. Endocrinology 99: 625–634
Luft R, Hall K (1975) Somatomedins and some other growth factors. Adv Metab Disord 8: 437
Madden JW, Gertman PM, Peacock EE (1970) Dimethylnitrosamine - Induced hepatic cirrhosis: a new canine model of an ancient human disease. Surgery 68: 260–268
Magee PN (1966) Toxic liver necrosis. Lab Invest 15: 111–130
Mahley RW, Innerarity TL (1977) Interaction of canine and swine lipoproteins with the low density lipoprotein receptor of fibroblasts as correlated with heparin/Manganese precipitability. J Biol Chem 252: 3980–3986
Mahon DC, Oloffs PC, Hard wick DF (1978) Interactions, in rats, between CCl4-induced liver cirrhosis and chronic treatment with a organochlorine insecticide chlordane. Clin Biochem 11: 135–136
Mainardi CL, Vater CA, Werb Z, Harris ED Jr (1976) Rheumatoid synovial collagenase: a proposed mechanism for its release, activation and protection from inhibition in vivo. Arthritis Rheum 19: 809
Maini RN (1978) The clinical and pathogenetic significance of rheumatoid factors. Aust NZJ Med [Suppl 1] 8: 51–56
Malemud FJ, Janoff A (1975) Human polymorpho nuclear leukocyte elastase and cathepsin G mediate the degradation of lopine articular cartilage proteoglycan. Ann NY Acad Sei 256: 254–262
Malumed CJ, Sokoloff L (1977) The effect of prostaglandins on cultured lapine articular chondrocytes. Prostaglandins 13: 845–860
Mankin HJ (1975) The metabolism of articular cartilage in health and disease. In: Burleigh PMC, Poole AR (eds) Dynamics of connective tissue macromolecules. North Holland, Amsterdam Oxford, pp 327–356
Mankin HJ, Lippiello L (1971) The glycosaminoglycans of normal and arthritic cartilage. J Clin Invest 50: 1712–1719
Margolis RK, Crockett CP, Kiang WL, Margolis RU (1976) Glycosaminoglycans and glycoproteins associated with rat brain nuclei. Biochim Biophys Acta 451: 465–469
Margolis RK, Thomas MD, Crockett CP, Margolis RU (1979) Presence of chondroitin sulfate in the neuronal cytoplasm. Proc Natl Acad Sei USA 76: 1711–1715
Mark K von der (1981) Localization of collagen types in tissue. In: Hall DA, Jackson DS (eds) International review of connective tissue research, vol 9. Academic Press, New York, pp 265–324
Mark H von der, Mark K von der, Gay S (1976) Study of differential collagen synthesis during development of the chick embryo by immunofluorescence. Dev Biol 48: 237–249
Mark K von der, Gau V, Mark H von der, Müller PK (1977) Relationship between shape and type of collagen synthesized as chondrocytes loose their cartilage phenotype in culture. Nature 267: 531–532
Marks SC (1974) A discrepancy between measurements of bone resorption in vivo and in vitro in newborn osteopetrotic rats. Am J Anat 141: 329–339
Marmion BP (1976) A microbiologist‘s view of investigative rheumatology. In: Dumonde DC (ed) Infection and immunology in the rheumatic diseases. Blackweles Scientific Publications, Oxford, pp 245–258
Maroudas A (1970) Effect of fixed charge density of the distribution and diffusion coefficients of salutes in cartilage. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol 3. Academic Press, London New York, pp 1389–1401
Maroudas A (1973) Physico-chemical properties of articular cartilage. In: Freeman MAR (ed) Adult articular cartilage. Pitman Medical, London, pp 131–170
Maroudas A (1976) Balance between swelling pressure and collagen tension in normal and degenerate cartilage. Nature 260: 808–809
Maroudas A, Evans H, Almeida L (1973) Cartilage of the hip joint. Topographical variation of glycosaminoglycan content in normal and fibrillated tissue. Ann Rheum Dis 32: 1–9
Maroudas A, Muir H, Wingham J (1969) The correlation of fixed negative charge with glycosaminoglycan content in human articular cartilage. Biochim Biophys Acta 117: 492–500
Marshall RN, Underwood LE, Yoina SJ (1974) Characterization of the insulin and somatomedin-C receptors in human placental cell membranes. J Clin Endocrinol Metab 39: 283–292
Martin GR, Byers PH, Piez KA (1975) Procollagen. Adv Enzymol 42: 167–191
Martini GA, Bode Ch (1970) Zur Epidemiologie der Leberzirrhose. Internist (Berlin) 11: 84–93
Matalon R, Dorfman A (1968) The accumulation of hyaluronic acid in cultured fibroblasts of the Marfan syndrome. Biochem Biophys Res Commu 32: 150–154
Matalon R, Dorfman A (1969) Acid mucopolysaccharides in fibroblasts. Lancet 2: 838–851
Matalon R, Dorfman A (1972) L-Iduronidase in cultured human fibroblasts and liver. Biochem Biophys Res Commun 42: 340–345
Matalon R, Dorfman A (1974) Sanfilippo A Syndrom. Sulfamidase deficiency in cultured skin fibroblasts and liver. J Clin Invest 54: 907
Mathews BF (1953) Composition of articular cartilage in osteoarthritis. Changes in collagen/chon-droitin sulphate ratio. Br Med J 2: 660–671
Mathews MB (1975) Connective tissue. Springer, Berlin Heidelberg New York
Mathews MB, Glagov S (1966) Acid mucopolysaccharide patterns in ageing human cartilage. J Clin Invest 45: 1103–1111
Maxwell WA, Spicer SS, Miller RL, Halushka PV, Westphal MC, Setzer MS (1977) Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva ( Myositis ossificans progres¬siva ). Am J Pathol 87: 483–498
Mayne R, Vail MS, Miller EJ (1975) Analysis of changes in collagen biosynthesis that occur when chick chondrocytes are grown in 5-bromo-2/-deoxyuridine. Proc Natl Acad Sei USA 72: 2310–2313
Mayne R, Vail MS, Mayne PM, Miller EJ (1976) Changes in type of collagen synthesized as clones of chick chondrocytes grow and evantually lose division capacity. Proc Natl Acad Sei USA 73: 1674–1678
McCord JM (1974) Free radicals and inflammation: Protection of synovial fluid by Superoxid dismutase. Science 185: 529–531
McDevitt CA, Gilbertson EMM, Muir H (1977) An experimental model of osteoarthritis; early morphological and biochemical changes. J Bone Joint Surg [Br] 59: 24
McDevitt CA, Muir H (1976) Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog. J Bone Joint Surg [Br] 58: 94–101
McKeehan WL, Generoux DP, Ham RG (1978) Assay and partial purification of factors from serum that control multiplication of human diploid fibroblast. Biochem Biophys Res Commun 80: 1013–1021
McKusick VA (1972) Heritable disorders of connective tissue, 3rd ed. Mosby, St. Loui
McKusick VA, Martin GR (1975) Molecular defects in collagen. Ann Intern Med 82: 585–587
McLean EK, McLean AEM, Sutton PM (1969) Instant cirrhosis: An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobar- bitone. Br J Exp Pathol 50: 502–506
Meachim G, Stockwell RA (1973) The matrix. In: Freeman MAR (ed) Adult articular cartilage. Pitman Medical, London, p 1
Megyesi K, Kahn CR, Roth J (1975) The NSILA-S receptor in liver plasma membranes. Characterization and comparison with the insulin receptor. J Biol Chem 250: 8990–8996
Meier F, Hay ED (1974) Stimulation of extracellular matrix synthesis in the developing corneaby glycosaminoglycans. Proc Natl Acad Sei USA 71: 2310–2313
Meigel WN, Müller PK, Potz BF, Sorensen N, Spranger J (1974) A constitutional disorder of connective tissue suggesting a defect in collagen biosynthesis. Klin Wochenschr 52: 906–912
Meigel WN, Gay S, Weber L (1977) Dermal architecture and collagene type distribution. Arch Dermatol Res 259: 1–10
Mellbye OJ, Naes B, Munthe E (1976) Complement and immunoglobulins in synovial fluid from synovectomised patients with rheumatoid arthritis. Ann Rheum Dis 35: 233–239
Melmon KL, Webster ME, Goldfinger SE, Seegmiller JE (1967) The presence of a kinin in inflammatory synovial effusion from arthritides of varying etiologies. Arthritis Rheum 10: 13–20
Menander-Huber KB, Huber W (1977) Orgotein, the drug version of bovine Cu-Zu superoxide dismutase. II. A summary account of clinical trials in man and animals. In: Michelson AM, Cord IM, Fridovich I (eds) Superoxide and superoxide dismutases. Academic Press, London, pp 537–549
Menzel J, Steffen C, Kolarz G, Eberl R, Frank O, Thumb N (1976) Demonstration of antibodies to collagen and of collagen-anticollagen immune complexes in rheumatoid arthritis synovial fluids. Ann Rheum Dis 35: 446–450
Meretoja J, Natvig JB, Husby G (1976) Amyloid related serum protein ( SAA) in patients with inherited amyloidosis and certain viral conditions. Scand J Immunol 5: 169–174
Mestecky J, Miller EJ (1975) Presence of antibodies specific to cartilage-type collagen in rheumatoid synovial tissue. Clin Exp Immunol 22: 453–456
Meyer K, Linker A, Davidson EA, Weissman B (1953) The mucopolysaccharides of bovine cornea, J Biol Chem 205: 611–616
Michaeli D (1977) Immunochemistry of collagen. In: Atassi MZ (ed) Immunochemistry of proteins. Plenum Press, New York London, pp 371–399
Michels P, Kleesiek K (1983) Untersuchungen zur molekularen Struktur und intermolekularen Wech-selwirkung des Hyaluronats in der Synovialflüssigkeit. Rheologica Acta (im Druck)
Michelson AM, McCord JM, Fridovich I (1977) Superoxide and superoxide dismutases. Academic Press, London
Mihaesco E, Mihaesco C (1965) Mucopolysaccharides in experimental hepatic fibrosis. Experientia 21: 598–599
Mikkonen L, Lampiaho K, Kulonen E (1966) Effect of thyroid hormones, somatotrophin, insulin and corticosteroids on the synthesis of collagen in granulation tissue both in vivo and in vitro. Acta Endocrinol (Kbh) 51: 23–31
Miller EJ (1971) Isolation and characterization of a collagen from chick cartilage containing three identical a-chains. Biochem 10: 1652–1658
Miller EJ (1973) A review of biochemical studies on the genetically distinct collagens of the skeletal system. Clin Orthop 92: 260–280
Miller EJ (1976) Biochemical characteristics and biological significance of the genetically distinct collagens. Mol Cell Biochem 13: 165–192
Miller EJ (1978) The collagen of joints. In: Sokoloff L (ed) The joints and synovial fluid. Academic Press, New York San Francisco London, pp 205–242
Miller EJ, Epstein EH, Piez KA (1971) Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human, skin and cartilage collagen. Biochem Biophys Res Commun 42: 1024–1029
Miller EJ, Matukas VJ (1969) Chick cartilage collagen: A new type of al chain not present in bone or skin of the species. Proc Natl Acad Sei USA 64: 1264–1268
Mitoma C, Smith TE, Davidson JD, Udenfriend S, Dacosta SM, Sjoerdsma A (1959) Improvement in methods for measuring hydroxyproline: application to human urine. J Lab Clin Med 53: 970–976
Miyazawa F, Olijnyk OR, Tilley CJ, Tamaoki T (1967) Interactions between dextransulphate and Escherichia coli ribosomes. Biochim Biophys Acta 145: 96–104
Moczar M, Moczar E, Robert L (1970) Composition of glycopeptides obtained by proteolytic digestion of the media of porcine aorta. Atherosclerosis 12: 31–40
Momburg M, Stuhlsatz HW, Vögeli H, Vojtisek O, Eylau O, Greiling H (1976) Klinisch-chemische Veränderungen in der Synovialflüssigkeit nach intraartikulärer Injektion eines Glykosaminogly- kanpolysulfats. Yerh Dtsch Ges Rheumatol 4: 383–390
Moore S, Pepper DS (1976) Identification and characterization of a platelet specific release product: ß-thromboglobulin. In: Gordon JL (ed) Platelets in biology and pathology. Elsevier/North Holland Biomedical Press, Amsterdam, p 293
Moro L, Smith BS (1977) Identification of collagen al(I)trimer and normal type I collagen in a polyoma virus-induced mouse tumor. Arch Biochem Biophys 182: 33–41
Morrione TG (1947) Quantitative study of collagen content in experimental cirrhosis. J Exp Med 85: 217–225
Müller J (1836) Ann Phys Chem 38: 295
Müller PK, Lemmen C, Gay S, Gauss V, Kühn K (1977) Immunochemical and biochemical study of collagen synthesis by chondrocytes in culture. Exp Cell Res 108: 47–55
Muir H (1977) Molecular approach to the understanding of osteoarthrosis. Ann Rheum Dis 36: 199–208
Murota S, Abe M, Otsuka K (1977) Stimulatory effect of prostaglandins on the production of hexosamine-containing substances by cultured fibroblasts. (3) Induction of hyaluronic acid synthetase by prostaglandin F2a. Prostaglandins 14: 983–991
Muthia P, Stuhlsatz HW, Greiling H (1974) Composition of corneal proteoglycans. Hoppe Seylers Z Physiol Chem 355: 924–934
Muto M, Yoshimura M, Okayama M, Kaji A (1977) Cellular transformation and differentiation. Effect of Rons sarcoma virus transformation on sulfated proteoglycan synthesis by chicken chondrocytes. Proc Natl Acad Sei USA 74: 4173–4177
Mutoh S, Funakoshi I, Yamashina I (1978) Isolation and characterization of proteoheparansulfate from plasma membranes of an ascites hepatoma, AH 66. J Biochem (Tokyo) 84: 483–489
Myers RR, Negami S, White RK (1966) Dynamic mechanical properties of synovial fluid. Biorheology 3: 197–209
Myllyllä R, Risteli J, Kivirikko KI (1975) Assay of collagen galactosyltransferase and collagen gluco- syltransferase activities and preliminary characterization of enzymic reactions with transferase from chick embryo cartilage. Eur J Biochem 52: 401–410
Myllyllä R, Tundermann L, Kivirikko KI (1977) Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence. Eur J Biochem 80: 349–357
Nagai Y (1973) Yertebrale collagenase: Further characterization and the significance of its latent form in vivo. Mol Cell Biochem 1: 137–145
Nakagawa H, Iheda M, Tsurufuji S (1975) A protective action of an anti-inflammatory steroid on collagen synthesis in rat carrageenin granuloma in vitro. J Pharm Pharmacol 27: 794–796
Nakagawa H, Tsurufuji S (1972) Action of methasone disodium phosphate on the metabolism of collagen and noncollagen protein in rat carrageenin granuloma. Biochem Pharmacol 21: 839–846
Nakashima Y, Ferrante N Di, Jacoson RL, Pownal HJ (1975) The interaction of human plasma glycosaminoglycans with plasma lipoproteins. J Biol Chem 250: 5386–5392
Nakasawa K, Suzuki N, Suzuki S (1975) Sequential degradation of keratan sulfate by bacteriol enzymes and purification of a sulfatase in the enzymatic system. J Biol Chem 250: 905–911
Narayanan AS, Sandberg LB, Ross R, Layman DL (1976) The smooth muscle cell. III. Elastin synthesis in arterial smooth muscle cell culture. J Cell Biol 68: 411–419
Nevo Z, Dorfman A (1972) Stimulation of chondromucoprotein synthesis in chondrocytes by extracellular chondromucoprotein. Proc Natl Acad Sci USA 69: 2069–2072
Newcombe DS, Fahey JV, Isbikawa Y (1977) Hydrocortisone inhibition of the bradykinin activation of human synovial fibroblasts. Prostaglandins 13: 235–244
Nieduszynski I A, Atkins EDT (1973) Conformation of mucopolysaccharides: X-ray fibre diffraction of heparin. Biochem J 135: 729–733
Nieduszynski I A, Atkins EDT (1975) Molecular conformations of heparan sulphate and heparin. In: Atkins EDT, Keller A (eds) Structure of fibrous biopolymers. Butterworths, London, pp 323–334
Niewiarowski S (1977) Proteins secreted by the platelet. Thromb Haemostas 38: 924–938
Nimmi M, Deshmukh K (1973) Differences in collagen metabolism between normal and osteo-arthrotic human articular cartilage. Science 181: 751–752
Nishida-Fukuda M, Egami F (1970) Enzymatic degradation of kerato sulphates. Biochem J 119: 39–47
Noda M (1965) Studies on fractional determination of the acid mucopolysaccharides in the cutaneous tissues. Japn J Dermatol 75: 609–633
Norval M, Graham A, Marmion BP (1976) Cytology of rheumatoid cells in culture. IV. Further investigations of cell lines cocultivated with rheumatoid synovial cells. Ann Rheum Dis 35: 297–305
Norval M, Marmion BP (1976) Attempts to identify viruses in rheumatoid synovial cells. Ann Rheum Dis 35: 106–113
O‘Brien JS (1972) Sanfilippo syndrome: Profound dificiency of a-acetyl glucosaminidase activity in organs and skin fibroblasts from type B patients. Proc Natl Acad Sci USA 69:1720–1722
O‘Brien JF, Cantz M, Spranger J (1974) Maroteaux-Lamy disease (mucopolysaccharidosis VI), subtype A: deficiency of a N-acetylgalactosamine-4-sulfatase. Biochem Biophys Res Commun 60:1170–1177
Obrink B (1975) In: Atkins EDT, Keller A (eds) Structure of fibrous biopolymers. Butterworths, London, pp 81
Ogston AG (1970) The biological functions of the glycosaminoglycans. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix. Academic Press, London New York, pp 1231–1240
Ogston AG, Stanier JE (1951) The dimensions of the particle of hyaluronic acid complex in synovial fluid. Biochem J 49: 585–599
Ogston AG, Stanier JE (1953) The physiological function of hyaluronic acid in synovial fluid; viscous elastic and lubricant properties. J Physiol (Lond) 119: 244–252
Ohlsson K (1978) Purification and properties of granulocyte collagenase and elastase. In: Havemann K, Janoff A (eds) Neutral proteases of human polymorphonuclear leukocytes. Urban Schwar- zenberg, Baltimore Miinchen, pp 89–101
Ohlsson K, Olsson I (1974) The neutral proteases of human granulocytes. Isolation and partial characterization of granulocyte elastase. Eur J Biochem 42: 519–527
Ohnishi T, Yamamoto K, Terayama H (1973) Disappearance of acid mucopolysaccharides from the cell coats in mitosis-induced mouse-liver. Histochemistry 36: 15–20
Ohnishi T, Ohshima E, Ohtsuka M (1975) Effect of liver cell coat acid mucopolysaccharide on the appearance of density-dependent inhibition in hepatoma cell growth. Exp Cell Res 93: 136–142
Ohuchi K, Sato H, Tsurufuji S (1976) The contents of prostaglandin E and prostaglandin F2a in the exudate of carrageenin granuloma of rats. Biochim Biophys Acta 424 /3: 439–448
Oikarinen A (1977) Effect of Cortisol acetate on collagen biosynthesis and on the activities of prolyl hydroxylase, lyryl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in chick-embryo tendon cells. Biochem J 164: 533–539
Oldberg A, Höök M, Öbrink B, Pertoft H, Rubin K (1977) Structure and metabolism of rat liver heparan sulphate. Biochem J 164: 75–81
Olden K, Pratt RM, Yamada KM (1978) Role of carbohydrates in protein secretion and turnover: effects of Tunicamycin on the major cell surface glycoprotein of chick embryo fibroblasts. Cell 13: 461–473
Olivecrona T, Bengtsson G, Marklung S-E, Lindahl U, Höök M (1977) Heparin - lipoprotein lipase interactions. Fed Proc 36: 60–65
Oliver RHP, Sutton PM (1966) The effects of partial hepatectomy on portal pressure in rats. Br J Surg 53: 138–141
Oronsky AL, Buermann CW (1976) Phagocytic release of human leukocyte neutral proteases. Analysis of cartilage degradation products. Arch Biochem Biophys 176: 539–546
Oronsky AL, Buermann CW (1978) Granulocyte neutral proteases in arthritis. In: Havemann K, Janoff A (eds) Neutral proteases of human polymorphonuclear leukocytes. Urban Schwarzenberg, Baltimore München, pp 361–372
Osmand AP, Friedenson B, Gewürz H, Painter RH, Hofmann T, Shelton E (1977) Characterization of a C-reactive protein and the complement subcomponent Clt as homologous protein displaying cyclic pentameric symmetry (pentraxins). Proc Natl Acad Sei USA 74: 739–743
Ott U, Hahn E, Moshudis E, Bode JC, Martini GA (1977) Immunhistologischer Nachweis von Typ I- und Typ III-Kollagen in Leberbiopsien. Frühe und späte Veränderungen bei alkoholischer Lebererkrankung. Verh Dtsch Ges Inn Med 83: 537–540
Palmer DG (1978) Complement in the pathogenesis of rheumatic disease. Aust NZJ Med [Suppl 1] 8: 57–60
Palmer MA, Piper PJ, Vane JR (1973) Release of rabbit aorta contracting substance ( RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs. Br J Pharmacol 49: 226–242
Palmiter RD, Davidson JM, Gagnon G, Rowe DW, Bornstein P (1979) NH2-terminal sequence of the chick pro a-l-(I) chain synthesized in the reticulocyte lysate system. Evidence for a transient hydrophobic leader sequence. J Biol Chem 254: 1433–1436
Palmiter RD, Moore PB, Multibill ER, Entage S (1976) A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: a receptor translation hypothesis. Cell 8: 557–572
Panayi GS (1978) Humoral immunity in rheumatoid arthritis. In: Panayi GS (ed) Rheumatoid arthritis an related coditions. Annual Research Reviews, vol 2. Churchill Livingstone, Edinburgh, pp 23–28
Partridge SM (1966) Biosynthesis and nature of elastin structures. Fed Proc 25: 1012–1029
Pasternack A, Tiilikainen A (1977) HLA 27 in rheumatoid arthritis and amyloidosis. Tissue Antigens 9: 80–89
Pawlowski PJ, Gillette MT, Martineil J, Lukens NL (1975) Identification and purification of collagen- synthesizing polysomes with anti-collagen antibodies. J Biol Chem 250: 2135–2142
Paz MA, Henson E, Blumenfeld OO, Seifter S, Gallop PM (1971) Dehydromerodesmosine and merodesmosine in elastin. Biochem Biophys Res Commun 44: 1518–1523
Penttinen RP, Lichtenstein JR, Martin GR, McKusick VA (1975) Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta. Proc Natl Acad Sei USA 72: 586–589
Perlish JS, Bashey RI, Stephens RE, Fleischmajer R (1976) Connective tissue synthesis by cultured scleroderma fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts. Arthritis Rheum 19: 891–901
Perricone E, Brandt KD (1978) Entancement of urate solubility by connective tissue. I. Effect of proteoglycan aggregates and buffer cation. Arthritis Rheum 21: 453–460
Peters HD (1976) Wirkung von Prostaglandinen auf die cAMP-abhängige Glykosaminoglykansyn- these in Fibroblastenkulturen: Einfluß von nichtsterioidalen Antiphlogistika und Glukokortikoiden. Habilitationsschrift, Hannover
Peters HD, Karzel K, Padberg D, Schönhöfer PS, Dinnendahl V (1974) Influence of prostaglandin Et on cyclic 3,5-AMP levels and glycosaminoglycan secretion of fibroblasts cultured in vitro. Pol J Pharmacol Pharm 26: 41–49
Phelps P, McCarty DJ Jr (1966) Crystal-induced inflammation in canine joints. II. Importance of polymorphonuclear leukocytes. J Exp Med 124: 115–126
Phillips LS, Vassilopoulou-Sellin R (1980) Somatomedins. N Engl J Med 302: 371–376
Piez KA (1968) Cross-linking of collagen and elastin. Annu Rev Biochem 37: 547–570
Piez KA (1976) Primary structure. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York London, pp 1–44
Piez KA, Miller A (1974) The structure of collagen fibrills. J Supramol Struct 2: 121–137
Pigman W (1978) Connective tissue glycoproteins. In: Horowitz MI, Pigman W (eds) The glycoconju-gates, vol II. Academic Press, New York, pp 73–77
Pinneil SR, Krane SM, Kenzora JE, Glimcher MJ (1972) Heritable disorder of connective tissue. Hydroxylysine - deficient collagen disease. N Engl J Med 286: 1013–1020
Pinneil SR, Martin GR (1968) The cross-linking of collagen and elastin: Enzymatic conversion of lysine in peptide linkage to a-aminoadipio-Delta-semialdehyde by an extract from bone. Proc Natl Acad Sei USA 61: 708–714
Piper PJ, Vane JR (1969) Release of additional factors in anaphylaxis and its antagonism by inflam¬matory drugs. Nature 223: 29–35
Pita JC, Cuervo LA, Madruga JE, Müller FJ, Howell DS (1970) Evidence for a role of protein polysaccharides in regulation of mineral. Phase separation in calcifying cartilage. J Clin Invest 49: 2188–2197
Podrazky V, Stokrova S, Fric I (1975) Elastin - Proteoglycan interaction, conformational changes of a-Elastin induced by the interaction. Connect Tissue Res 4:51–54, Gordon and Breach Science Publishers, New York London Paris
Poole AR, Hembry RM, Dingle JT, Pinder I, Ring EFG, Cosh J (1976) Secretion and localisation of cathepsin D in synovial tissues removed from rheumatoid and traumatized joints. Arthritis Rheum 19: 1295–1307
Pope RM, Martin GR, Lichtenstein JR, Penttinen R, Gerson B, Rowe DW, McKusick VA (1975b) Patients with Ehlers-Danlos-syndrome Typ IV, lack type III collagen. Proc Natl Acad Sei USA 72: 1314–1316
Popper H (1975) Overview of past and future of hepatic collagen metabolism. In: Popper H, Becker K (eds) Collagen metabolism in the liver. Stratton Intercontinental Medical Book, New York, pp 227–242
Popper H (1977) Pathologic aspects of cirrhosis. Am J Pathol 87: 228–258
Popper H (1978) Die Leberfibrose - Entstehung, Dynamik und klinische Bedeutung. Leber Magen Darm 8: 65–72
Popper H, Becker E (Hrsg) (1975) Collagen metabolism in the liver. Stratton Intercontinental Medical Book, New York
Popper H, Bianchi L, Reutter W (1976) Membrane alterations as basis of liver injury. MTP Press, Lancaster
Popper H, Davidson CS, Leevy CM, Schaffner F (1969) The social impact of liver disease. N Engl J Med 281: 1455–1458
Popper H, Kent G (1975) Cirrhosis. Clin Gastroenterol 2: 225–463
Popper H, Paronetto F, Schaffner F, Perez V (1961) Studies on hepatic fibrosis. Lab Invest 10: 265–290
Popper H, Udenfriend S (1970) Hepatic fibrosis, correlation of biochemical and morphologic investigations. Am J Med 49: 707–721
Postlethwaite AE, Seyer JM, Kang AH (1978) Chemotactic attraction of human fibroblasts to type I, II, and III collagens and collagen-derived peptides. Proc Natl Acad Sei USA 75: 871–875
Pott G, Gerlach U (1977) Leberfibrose - Anmerkungen zur Pathophysiologic und Aktivitätsdiagnostik. Med Welt 28: 2030–2034
Pras M, Reschef T (1972) The acid-soluble fraction of amyloid-a fibril forming protein. Biochim Biophys Acta 271: 193–203
Pras M, Schubert M, Zucker-Franklin D, Rimon A, Franklin EC (1968) The characterization of soluble amyloid prepared in water. J Clin Invest 47: 924–933
Pras M, Zucker-Franklin D, Rimon A, Franklin EC (1969) Physical, chemical and ultrastructural studies of water-soluble human amyloid fibrils. J Exp Med 130: 777–784
Priest RE (1967) Endocrine control of connective tissue metabolism. In: Wagner BM, Smith DE (eds) The connective tissue. Williams Wilkens, Baltimore, pp 50–60
Priest RE, Moinuddin JS, Priest JH (1973) Collagen of Marfan-syndrome is abnormally soluble. Nature 245: 264–266
Prockop DJ, Berg RA, Kivirikko KI, Uitto J (1976) Intracellular steps in the biosynthesis of collagen. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York London, pp 163–273
Pryce-Jones RH, Saklatvala J, Wood GC (1974) Neutral proteases from the polymorphonuclear leukocytes of human rheumatoid synovial fluid. Clin Sei Mol Med 47: 403–414
Quintarelli G, Dellovo MC (1970) The State of aggregation of the intercellular matrix of various cartilage tissues. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol. III. Academic Press, New York, p 1403
Rabes HM (1976) Kinetics of hepatocellular proliferation after partial resection of the liver. In: Popper H, Schaffner F (eds) Progress in liver diseases. Grune Stratton, New York San Francisco London, pp 83–99
Radhakrishnamurthy B, Ruiz HA, Berenson GS (1977) Isolation and characterisation of proteoglycans from bovine aorta. J Biol Chem 252: 4831–4841
Rainsford KD (1978) The effects of Aspirin and other non-steroid anti-inflammatory/analgesic drugs on gastro-intestinal mucus glycoprotein biosynthesis in vivo: relationship to ulcerogenic actions. Biochem Pharmacol 27: 877–885
Raisz LG, Trummel CL, Holick MF, Luca HF de (1972) 1,25-Dihydroxycholecalciferol: A potent stimulator of bone resorption in tissue culture. Science 175: 768–769
Ramachandran GN (1967) Structure of collagen at the molecular level. In: Ramachandran GN (ed) Chemistry of collagen. Academic Press, New York, pp 103–183
Ramachandran GN, Ramakrishnan C (1976) Molecular structure. In: Ramachandran GN, Reddi AH (ed), Biochemistry of collagen. New York, Plenum Press, pp 45–84
Ramachandran GN, Reddi AH (1976) Biochemistry of collagen. Plenum Press, New York London
Rath NC, Reddi AH (1979) Collagenous bone matrix is a local mitogen. Nature 278: 855–857
Rau R (1978) Die Leber bei entzündlichen Erkrankungen. Der Rheumatismus, Bd 43. Steinkopff, Darmstadt
Rauterberg J, Voss B (1978) Characterization and histoimmunological localization of basement mem- brans collagens in the arterial wall. In: Biochemistry of normal and pathological connective tissue, Colloques Int. CNRS 287: 220
Rechler MM, Fryklund L, Nissley SP, Hall K, Podskalny JM, Skottner A, Moses AC (1978) Purified human somatomedin A and rat multiplication stimulating activity. Eur J Biochem 82: 5–12
Rechler MM, Podskalny JM, Nissley P (1977) Characterization of the binding of multiplication- stimulating activity to a receptor for growth polypeptides in chick embryo fibroblasts. J Biol Chem 252: 3898–3910
Reddi AH, Hascall WC, Hascall GK (1978) Changes in proteoglycan types during matrix-induced cartilage and bone development. J Biol Chem 253: 2429–2436
Reddi HH (1976) Collagen and cell differentiation. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York, pp 449–478
Remberger K, Gay S, Adelmann BC, Timpl R (1975 a) Immunhistochemical demonstration of different collagen-types in synovial membranes and synovial fluids of rheumatoid arthritis. Scand J Rheumatol [Suppl 8] 4:36–02 Abstr
Reuber MD, Dove LF, Glover EL (1968) Severe cirrhosis with hepatic vein thrombosis in rats given carbon tetrachloride and 3-methylcholanthrene. Pathol Microbiol (Basel) 32: 41–48
Reuber MD, Glover EL (1967) Cholangiofibrosis in the liver of Buffalo strain rats in jected with carbon tetrachloride. Br J Exp Pathol 48: 319–322
Reuber MD, Glover EL (1968) Carbon tetrachloride induced cirrhosis: Effect of age and sex. Arch Pathol 85: 275–279
Reuber MD, Grollman S, Glover EL (1970) Effect of 3-Methylcholanthrene on experimentally in¬duced cirrhosis. Arch Pathol 89: 531–536
Reynolds JI, Werb Z (1975) The relation of phagozytosis to the secretion of non-lysosomal enzymes by connective tissue cells. In: Slavkin HC, Greulich RC (eds) Extracellular matrix influences on gene expression. Academic Press, New York, pp 225–240
Rhoads RE, Udenfriend S (1968) Decarboxylation of a-ketoglutarate, coupled to collagen proline hydroxylase. Proc Natl Acad Sei USA 60: 1473–1478
Riggs BL, Jowsey J, Kelly PS, Jones WD, Maher FT (1969) Effect of sex hormones on bone in primary osteoporosis. J Clin Invest 48: 1065–1072
Rinderknecht H, Humbel RE (1976) Polypeptides with non-suppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization and some biological properties of forms I and II. Proc Natl Acad Sei USA 73: 2363–2369
Rindler R, Schmalzl F, Braunsteiner H (1974) Isolierung und Charakterisierung der chymotrypsin- ähnlichen Protease aus neutrophilen Granulozyten des Menschen. Schweiz Med Wochenschr 104: 132–133
Robert B, Robert L (1970) Studies on the structure of elastin and the mechanism of action of elastolytic enzymes. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol. 2. Academic Press, London New York, pp 665–670
Robert B, Robert L (1974) Structural glycoproteins of connective tissue. Their role in morphogenisis and immunopathology. In: Fricke R, Hartmann (eds) Connective Tissues. Springer, Berlin New York, pp 240–256
Robert L (1973) Aging of connective tissues-skin. Frontiers of matrix biology. S. Karger, Basel München
Robert L, Robert B (1973) Aging of connective tissues-skin. Routiert of matrix biology, vol 1. Karger, Basel
Robert L, Dorrell RW, Robert B (1970) Immunological properties of connective tissue glycoproteins. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol 3. Academic Press, New York, pp 1591–1614
Roberts MH, Howell DRS, Bramhall JL, Reubner B (1960) Epidermolysis bullosa letalis. Pediatrics 25: 283–290
Robertson WB (1958) Hormonal effects on collagen formation in granulomas. Endocrinology 63: 250
Robertson WVB, Sanborn EC (1958) Hormonal effects on collagen formation in granulomas. Endocrinology 63: 250–251
Robinson HC, Horner AA, Höök M, Ögren S, Lindahl U (1978) A proteoglycan form of heparin and its degradation to single-chain molecules. The J Biol Chem 253, no. 19, Issue Oct. 10: 6687–6693
Robinson HJ, Granada JL (1974) Prostaglandins in synovial inflammatory disease. Surg Forum 25: 476–477
Roblin R, Albert SO, Gelb NA, Black PH (1975) Cell surface changes correlated with density- dependent growth inhibition. Glycosaminoglycan metabolism in 3T3, SU 3T3, and C on A selected revertant cells. Biochemistry 14: 347–357
Roden L (1970) Structure and metabolism of the proteoglycans of chondroitin sulfates and keratan sulfate. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix, vol II. Academic Press, London New York, pp 797–821
Roden L, Horowitz MJ (1978) Structure and biosynthesis of connective tissue proteoglycans. In: Horowitz MJ, Pigman W (eds) The glycoconjugates, vol II. Academic Press, New York San Francisco London, pp 13–71
Roden L, Schwartz NB (1975) Biosynthesis of connective tissue proteoglycans. In: Whelan WJ (ed) MTP Int Rev Sei Biochemistry Ser. 1. Biochemistry of carbohydrates, vol 5. University Park Press, Baltimore, pp 96–152
Roden L, Smith R (1966) Structure of the neutral trisaccharide of the chondroitin 4-sulphate-protein linkage region. J Biol Chem 241: 5949–5954
Rojkind M, Giambrone M-A, Biempica L (1979) Collagen types in normal and cirrhotic liver. Gastroenterology 76: 710–719
Rojkind M, Kershenobich E (1976) Hepatic fibrosis. In: Popper H, Schaffner F (eds) Progress in liver diseases. Grune Stratton, New York San Francisco London, pp 294–310
Rojkind M, Martinez-Palomo A (1976) Increase in type I and type III collagens in human alcoholic liver cirrhosis. Proc Natl Acad Sei USA 73: 539–543
Rosa M di, Girond JP, Willonghby DA (1971) Studies of the mediators of acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol 104: 15–29
Rosenberg RD (1977) Heparin: Structure - function relationship. Ups J Med Sei 82: Addendum
Rosenbloom J, Cywinski A (1976) Biosynthesis and secretion of tropoelastin by chick aorta cells. Biochem Biophys Res Commun 69: 613–620
Rosenbloom J, Endo R, Harsch M (1976) Termination of procollagen chain synthesis by puromycin. J Biol Chem 251: 2070–2076
Rosenbloom J, Harsch M, Jiminez S (1973) Hydroxyproline content determines the denaturation temperature of chick tendon collagen. Arch Biochem Biophys 158: 478–484
Rosenthal CJ, Franklin EC (1975) Variation with age and disease of an amyloid A protein-related serum component. J Clin Invest 55: 746–753
Rosenthal CJ, Franklin EC (1977) Serum amyloid A ( SAA) protein-interaction with itself and serum albumin. J Immunol 119: 630–634
Rosenthal CJ, Franklin EC, Frangione B, Greenspan J (1976) Isolation and partial characterization of SAA - an amyloid-related protein from human serum. J Immunol 116: 1415–1418
Ross R (1973) The elastic fiber. J Histochem Cytochem 21: 199–208
Ross R, Bornstein P (1969) The elastic fiber. I. The separation and partial characterization of its macromolecular components. J Cell Biol 40: 366–381
Ross R, Bornstein P (1970) Studies of the components of the elastic fiber. In: Balazs EA (ed) Chemistry and molecular biology of the intercellular matrix. Academic Press, London New York, pp 641–655
Ross R, Bornstein P (1971) Elastic fibers in the body. Sei Am 224: 44–52
Ross R, Harker L (1976) Hyperlipidemia and atherosclerosis. Science 193: 1094–1100
Ross R, Glomset J, Kariya B, Harker L (1974) A platelet - dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Natl Acad Sei USA 71: 1207–1210
Rubin AL, Drake MP, Davidson PF, Pfahl D, Speakman PT, Schmitt SO (1965) Effects of pepsin treatment on the interaction of tropocollagen molecules. Biochemistry 4: 181–190
Rubin E (1966) Autoradiographic characterization of sulfated acid mucopolysaccharides in experimental cirrhosis. J Histochem Cytochem 14: 688–689
Rubin E, Lieber CS (1974) Fatty liver alcoholic hepatitis and cirrhosis produced by alcohol impremates. N Engl J Med 92: 128–135
Rüttner JR, Rondez R (1960) Zur formalen Genese der Thioacetamid-Zirrhose der Ratte. Pathol Microbiol (Basel) 23: 113–119
Ryan GB, Majno G (1977) Acute inflammation. A review. Am J Pathol 86: 185–276
Rytämaa T, Toivonen H (1979) Chalones: concepts and results. Mech Ageing Dev 9: 471–480
Saarni H (1978) Cortisol effects on the glycosaminoglycan snythesis and molecular weight distribution in vitro. Biochem Pharmacol 27: 1029–1032
Saarni H, Hopsu-Havu VK (1977) Inhibition of acid mucopolysaccharide synthesis by hydrocortisone, hydrocortisone 17-butyrate and 17-methasone 17-valerate. Br J Dermatol 97: 505–507
Saarni H, Tammi M, Doherta NS (1978) Decreased hyaluronic acid synthesis, a sensitive indicator of Cortisol action on fibroblast. J Pharm Pharmacol 30: 200–201
Sajdera SW, Hascall VC (1969) Proteinpolysaccharide complex from bovine nasal cartilage. Comparison of low and high shear extraction procedures. J Biol Chem 244: 77–87
Sakakibara K, Saito M, Umeda M, Enaka K, Tsukada Y (1976) Native collagen formation by liver parenchymal cells in culture. Nature 262: 316–318
Sakakibara K, Takaoka T, Katsuta T, Umeda M, Tsukada Y (1978) Collagen fiber formation as a common property of epithelial liver cell lines in culture. Exp Cell Res 111: 63–71
Sakakibara K, Umeda M, Saito S, Nagase S (1977) Production of collagen and acidic glycosaminogly- cans by an epithelial liver cell clone in culture. Exp Cell Res 110: 159–165
Sakomoto S, Goldhaberm P, Glimpcher MJ (1973) Mouse bone collagenase. The effect of heparin on the amount of enzyme released in tissue culture and on the activity of the enzyme. Calcif Tissue Res 12: 247–258
Salin ML, McCord JM (1974) Superoxid dismutase in polymorphonuclear leukocytes. J Clin Invest 54: 1005–1009
Salmon WD Jr, Daughaday NH (1957) A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Med 49: 825–836
Salmon WD, Vail MR du (1970) A serum fraction with sulfation factor activity stimulates in vitro incorporation of leucine and sulfation to protein polysaccharide complexes, uridine into RNA, and thymidine into DNA of costal cartilage from hypophysectomized rats. Endocrinology 86: 721–727
Salmon WD, Vail MR du, Thompson EY (1968) Stimulation by insulin in vitro of incorporation of (35S) sulfat and (14C) leucine into protein-polysaccharide complex, (3H) uridine into RNA, and (3H) thymidine into DNA of costal cartilage from hypophysectomized rats. Endocrinology 82: 493–499
Sambe K, Kamegaya K, Oda M, Okazaki I (1974) Hepatic fibrosis. Mechanism of collagen fiber formation and resorption. In: Otaka Y (ed) Biochemistry and pathology of connective tissue. Thieme, Stuttgart, pp 249–276
Sandberg LB, Gray WR, Franzblau C (1977) Elastin and elastic tissue. Plenum Press New York London
Sandberg LB, Zeikus RD, Coltrain IM (1971) Tropoelastin purification from Copper-deficient swine: A simplified method. Biochim Biophys Acta 236: 542–545
Sapolsky AI, Altmann RD, Howell DS (1973) Cathepsin D activity in normal and osteoarthritis human cartilage. Fed Proc 32: 1489–1493
Sapolsky AI, Howell DS, Woessner JF Jr (1974) Neutral proteases and Cathepsin D in human articular cartilage. J Clin Invest 53: 1044–1053
Sapolsky AI, Keiser H, Howell DA, Woessner FJ (1976) Metallproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH. J Clin Invest 58: 1030–1041
Sasse J, Mark H, Mark K von der (1978) AB-Collagen: New marker for studies of muscle differentiation. J Cell Biol 79A: 323
Schaffner F, Popper H (1963) Capillarization of hepatic sinusoids in man. Gastroenterology 44: 239 - 242
Schaffrath D, Stuhlsatz HW, Greiling H (1976) Interactions of glycosaminoglycans with DNA synthesizing enzymes in vitro. Hoppe Seylers Z Physiol Chem 357: 499–508
Scheinberg MA, Cathcart ES (1976) A comprehensive study of humoral and cellular immune abnormality in 26 patients with systemic amyloidosis. Arthritis Rheum 19: 173–182
Scher I, Hamerman D (1972) Isolation of human synovial-fluid hyaluronate by density-gradient ultracentrifugation and evaluation of its protein content. Biochem J 126: 1073–1083
Schiller S (1961) The influence of the thyroid gland on metabolism of mucopolysaccharides in skin of rats. Fed Proc 20: 163
Schiller S (1976) The effect of hormones on synthesis of the region linking chondroitin sulfate to protein. Biochim Biophys Acta 451: 457–464
Schiller S, Slover GA, Dorfman A (1962) Effect of the thyroid gland on metabolism of acid mucopoly-saccharides in skin. Biochim Biophys Acta 58: 27–33
Schimpff RM, Donnadieu M, Glasinovic JC (1976) The liver as a source of somatomedin. Acta Endocrinol (Kbh) 83: 363–372
Schmut O, Hofmann H (1975) Generation of H202 during some non-enzymic reactions changing the hyaluronic acid molecule. Biochim Biophys Acta 411: 231
Schorlemmer HU, Allison AC (1976) Effects of activated complement components on enzyme secretion by makrophages. Immunology 31: 781–788
Schwartz NB, Dorfman A (1975) Stimulation of chondroitin sulfate proteoglycan production by chondrocytes in monolayer. Connect Tissue Res 3: 115–122
Schwarz W, Merker H-J, Jahnke A, Hofmann M (1958) Berl Med 88
Scott JE, Newton DJ (1975) The recovery and characterization of acid glycosaminoglycans in normal urine. Influence of a circadian rhythm. Connect Tissue Res 3: 157–164
Sellers A, Reynolds J (1977) Identification and partial characterization of an inhibitor of collagenase from rabbit bone. Biochem J 167: 353–360
Sellars A, Cartwright E, Murphy G, Reynolds J J (1977) Evidence that latent collagenase are enzyme inhibitor complexes. Biochem J 163: 303 - 307
Selye H (1961) Non-specific resistance. Ergeb Allg Pathol Pathol Anat 41: 209–241
Severson AR (1978) The effect of cyclic nucleotides on the incorporation of 3H-glucosamine into hyaluronate in bone culture. Horm Metab Res 10: 256–260
Seyer JM, Hutcheson ET, Kang AH (1976) Collagen polymorphism in idiopathic chronic pulmonary fibrosis. J Clin Invest 57: 1498–1507
Seyer JM, Hutcheson ET, Kang AH (1977) Collagen polymorphism in normal and cirrhotic human liver. J Clin Invest 59: 241–248
Seyer JM, Kang AH (1977) Covalent structure of collagen: Amino acid sequence of cyanogen bromide peptides from the amino terminal sequent of type III collagen of human liver. Biochemistry 16: 1158–1164
Seyer JM, Kang AH (1978) Covalent structure of collagen: Amino acid sequence of five consecutive CNBr peptides from type III collagen of human liver. Biochemistry 17: 3404–3411
Shapiro B, Pimstone BL (1977) A phylogenetic study of sulphation factor activity in 26 species. J Endocrinol 74: 129–135
Sheehan JK, Gardner KH, Atkins EDT (1978) Hyaluronic acid: A double helical structure in the presence of potassium at low pH and found also with the cations ammonium, rubidium and caesium. Zit. nach Comper und Laurent: Physiological function of connective tissue polysaccharides. Physiol Rev 58: 255-315
Shinozawa T, Yahara I, Imahori K (1968) Interaction of polyvinylsulphate with ribosomes. J Mol Biol 36: 305–319
Shirahama T, Cohen AS (1973) An analysis of the close relationship of lysosomes to early deposits of amyloid. Am J Pathol 73: 97–114
Shirahama R, Cohen AS (1975) Intralysosomal formation of amyloid fibrils. Am J Pathol 81: 101–116
Shuttleworth CA, Veis A (1972) The isolation of anionic phosphoproteins from bovine cortical bone VIA the periodate solubilization of bone collagen. Biochim Biophys Acta 257: 414–420
Siegel RC (1974) Biosynthesis of collagen cross-links: increased activity of purified lysyl oxidase with reconstituted collagen fibrils. Proc Natl Acad Sei USA 71: 4826–4830
Siegel RC, Martin GR (1970) Collagen cross-linking: enzymatic synthesis of lysine-derived aldehydes and the production of cross-linked components. J Biol Chem 245: 1653–1658
Siegel RC, Pinneil SR, Martin GR (1970) Cross-linking of collagen and elastin. Properties of lysyloxi-dase. Biochemistry 9: 4486–4492
Sievertsson H, Fryklund L, Uthne K, Hall K, Westermark B (1975) Isolation and chemistry of human somatomedins A and B. Adv Metab Disord 8: 47–69
Silbert JE, Luca S de (1969) Biosynthesis of chondroitin sulfate. III. Formation of A sulfated glycosa-minoglycan with a microsomal preparation from embryo cartilage. J Biol Chem 244: 876–881
Sipe JD, Ignaczak TF, Pollock PS, Glenner GG (1976) Amyloid fibril protein AA: Purification and properties of the antigenically related serum component as determined by solid phase radioimmunoassay. J Immunol 116: 1151–1156
Sirek OY, Sirek A, Fikar K (1977) The effect of sex hormones on glycosaminoglycan content of canine aorta and coronary arteries. Atherosclerosis 27: 227–233
Skinner M, Cohen AS (1976) Aspects of the amyloid P-component. In: Wegelius O, Pasternack A (eds) Amyloidosis. Academic Press, New York London, pp 336–352
Skinner M, Cohen AS, Shirahama T, Cathcart ES (1974) P-Component (pentagonal-unit) of amyloid:isolation, characterization and sequence analysis. J Lab Clin Med 84: 604–612
Slater TF (1969) Aspects of cellular injury and recovery. In: Bittor EE, Bittor N (eds) The biological basis of medicine. Academic Press, London, pp 369–408
Slavkin HC, Greulich RC (1975) Extracellular matrix influences on gene expression. Academic Press, New York London
Sletten K, Westermark P, Natvig JB (1976) Characterisation of amyloid fibril proteins from medullary carcinoma of the thyroid. J Exp Med 143: 993–998
Slobin LI (1976) The inhibition of elongation factor 1 activity by heparin. Biochem Biophys Res Commun 73: 539–547
Sly WS, Quinton BS, McAlister WH, Rimoin DL (1973) Beta-glucuronidase deficiency: report of clinical radiologic and biochemical features of a new mucopolysaccharidosis. J Pediatr 82: 249–256
Smith AF, Castor CW (1978) Connective tissue activation. XII. Platelet connective activating factors in patients with rheumatoid arthritis. J Rheumatol 5 /2: 177–183
Smith BD, McKenney KH, Lustberg ThJ (1977) Characterization of collagen precursors found in rat skin and rat bone. Biochemistry 16: 2980–2985
Smith DW, Abraham PA, Carnes WH (1975) Cross-linkage of salt-soluble elastin in vitro. Biochem Biophys Res Commun 66: 893–899
Smith DW, Brown DM, Carnes WH (1972) Preparation and properties of Salt-soluble elastin. J Biol Chem 247: 2427–2432
Smith DW, Weissman N, Carnes WH (1968) Cardiovascular studies on copper-deficient swine: XII. Partial purification of a soluble protein resembling elastin. Biochem Biophys Res Commun 31: 309–315
Smith DW, Abraham PA, Carnes WH (1977) Studies of the biosynthesis of a soluble precursor of elastin. In: Sandberg LB, Gray WR, Franzblau C (eds) Elastin and elastic tissue. Plenum Press, New York London, pp 385–395
Smith GL, Temin HM (1974) Purified multiplication-stimulating activity from rat liver cell conditioned medium: comparison of biological activities with calf serum, insulin and somatomedin. J Cell Physiol 84: 181–192
Smith KE, Hirsch CA, Henshaw EC (1973) Role of elongation factors and the effect of aurintricar- boxylic acid on the synthesis of polyphenylalanine. J Biol Chem 248: 122–130
Smith QT (1965) Urinary hydroxyprolin in various diseases. Acta Derm Venerol (Stockh) 45: 44
Smith QT (1967) Radioactivity of hydroxyproline from swine and collagens of normal and cortisone- treated rats. Biochem Pharmacol 16: 2171–2179
Smith QT, Allison DJ (1965) Cutaneous collagen and hexosamine and femur collagen of testosterone propionate treated rats of various ages. Biochem Pharmacol 14: 709–720
Smith R (1975) Myositis ossificans progressiva: a review of current problems. Semin Arthritis Rheum 4: 369–381
Sobel H (1953) The collagen and hexosamin content of the skin of normal and experimentally treated rats. Arch Biochem Biophys 46: 221
Sondergaard J, Greaves MW (1970) Pharmacological studies in inflammation due to exponse to ultraviolet radiation. J Pathol 101: 93–97
Spielvogel RL, Kersey JH, Goltz RW (1978) Mononuclear cell stimulation of fibroblasts collagen synthesis. Clin Exp Dermatol 3: 25–30
Spranger I (1974) Mucopolysaccharidosen. In: Handbuch der inneren Medizin, Bd 7/1. Springer, Berlin Heidelberg New York, S 209–270
Spranger I (1978) Klinisch-biochemische Reaktionen bei Mucopolysaccharidosen. In: Lang H, Rick W, Rokal L (Hrsg) Aktuelle Probleme der Pathobiochemie. Springer, Berlin Heidelberg New York, S 70–84
Srinivasan SR, Radhakrishnamurthy B, Berenson GS (1975) Studies on the interaction of heparin with serum lipoproteins in the presence of Ca2 Mg2, and Mn2. Arch Biochem Biophys 170: 334–340
Starkey PM, Barrett AJ, Burleigh MC (1977) The degradation of articular collagen by neutrophil proteinases. Biochim Biophys Acta 483: 386–397
Stastny P, Rosenthal M, Ziff M (1975) Lymphokines in the rheumatoid joint. Arthritis Rheum 18: 237–243
Steffen C (1974) Collagen anti-collagen immune complexes. Z Immunitaetsforsch Immunobiol 147: 229
Stein GS, Roberts RM, Davis JL, Head WJ, Stein JL, Throll CL, Veen J van, Welch DW (1975) Are glycoproteins and glycosaminoglycans components of the eukaryotic genome? Nature 258: 639–641
Stein Th, Keller R, Stuhlsatz HW, Greiling H, Ohst E, Müller E, Scharf HD (1982) Structure of the linkage region between polysaccharide chain and core protein in bovine corneal proteokera- tan sulfate. Hoppe-Seylers Z Physiol Chem 363: 825–833
Stenger RJ (1965) Fibrogenesis along the hepatic sinusoids in carbon tetrachloride-induced cirrhosis. An electron microscopic study. Exp Mol Pathol 4: 357
Stephens RW, Ghosh P, Taylor TKF, Gale CA, Swann JC, Robinson RG, Webb J (1975) The origins and relative distribution of polysaccharidoses in rheumatoid and osteoarthritic fluids. J Rheumatol 2: 393–900
Stoffyn P, Jeanloz RW (1960) The identification of the uronic acid component of dermatan sulfate ( Heparin, chondroitin sulfate B ). J Biol Chem 235: 2507–2510
Stuart JM, Postlethwaite AE, Kang AH (1976) Evidence for cell-mediated immunity to collagen in progressive systemic sclerosis. J Lab Clin Med 88: 601–607
Stuhlsatz HW (1979) Zur Struktur und Pathobiochemie Keratansulfathaltiger Proteoglykane. Habilitationsschrift, RWTH Aachen
Stuhlsatz HW, Greiling H (1976) The preparation dermatan sulfate. In: Hall DA (ed) The methodology of connective tissue research. Joynson-Bruvvers, Oxford, pp 137–146
Stuhlsatz HW, Eberhard A, Kristin H, Vojtisek O, Greiling H (1976) Die Glykosaminoglykane in der Synovialflüssigkeit bei chronischen Gelenkerkrankungen. Verh Dtsch Ges Rheumatol 4: 444–454
Stuhlsatz HW, Enzensberger W, Greiling H (1977) Influence of urate on connective tissue metabolism. In: Müller MM, Kaiser E, Seegmiller EJ (eds) Purine metabolism in man. II. Physiology, pharmacology and clinical aspects. Plenum Press, New York, pp 195–200
Stuhlsatz HW, Greiling H (1982) Proteoglycans and glycosaminoglycans of human joint cartilage in health, senescence, and disease. In: Varma RS, Varma R, Warren Pa (eds) Glycosaminoglycans and proteoglycans in physiological and pathological processes of body systems, Karger, Basel, pp 276–289
Sussmann M, Lichtenstein JR, Nigra TP, Martin GR, McKusick VA (1974) Hydroxylysine-deficient skin collagen in a patient with a form of the Ehlers-Danlos-syndrome. J Bone Joint Surg [Am] 56: 1228–1234
Suzuki S, Saito H, Yamagaty T, Anno K, Seno N, Kawai Y, Furuhashi T (1968) Formation of three types of disulfated disaccharides from chondroitin sulfates by chondroitinase digestion. J Biol Chem 243: 1543–1550
Suzuki S, Kojima K, Utsumi KR (1970) Production of sulfated mucopolysaccharides by established cell lines of fibroblastic and neu fibroblastic origin. Biochim Biophys Acta 222: 240–243
Suzuki S, Suzuki S, Nakamura N, Koizumi T (1976) The heterogeneity of dermatan sulfate and heparan sulfate in rat liver and a shift in the glycosaminoglycan contents in carbon tetrachloride- damaged liver. Biochim Biophys Acta 428: 166–181
Sweet MBE, Thonar EJ-MA, Immelman AR, Solomon L (1977) Biochemical changes in progressive osteoarthrosis. Ann Rheum Dis 36: 387–398
Sykes BC, Partridge SM (1972) Isolation of a soluble elastin from lathyritic chicks. Biochem J 130: 1171–1172
Takano K, Hall K, Ritzen M, Oselius L, Sievertsson H (1976) Somatomedin A in human serum determined by radioreceptor assay. Acta Endocrinol (Kbh) 82: 449–459
Takeuchi J (1966) Growth-promoting effect of acid mucopolysaccharides on Ehrlich ascites turnover. Cancer Res 26: 797–802
Takeuchi J, Sobne M, Shamoto M, Yoshida M, Sato E, Leighton J (1977) Cell surface glycosaminoglycans of cell line MDCK derived from canine kidney. Cancer Res 37: 1507–1512
Tanimoto K, Cooper R, Johnson JS, Vaugham JH (1975) Complement fixation by rheumatoid factor. J Clin Invest 55: 437–4145
Tanzer ML (1965) Experimental lathyrism. Int Rev Connect Tissue Res 3: 91–112
Tanzer ML (1973) Cross-linking of collagen. Science 180: 561–566
Tanzer ML, Rowland FN, Murray LW, Kaplan J (1977) Inhibitory effects of tunicamycin on procollagen biosynthesis and degradation. Biochim Biophys Acta 500: 187–196
Taubenhaus M (1952) Hormonal interaction in regulation of granulation tissue formation. Endocrinology 51: 183
Taylor SR, Cook RT (1977) Heparin causes a redistribution of chromosomal proteins. FEBS Lett 78: 321–325
Teien AN, Abildgaard U, Höök M (1976) The anticoagulant effect of heparan sulfate and dermatan sulfate. Thromb Res 8: 859–867
Teilum GJ (1964) Amyloidosis secondary to a gamma-globulinaemia. J Pathol Bacteriol 88: 317–320
Thompson EB, Lippman ME (1974) Mechanism of action of glucocorticoids. Metabolism 23: 159–202
Thonar EJ-MA, Sweet MBE, Immelman AR, Lyons G (1978) Hyaluronate in articular cartilage:age-related changes. Calcif Tissue Res 26: 19–21
Thorngren K-G, Hansson LI (1973) Effect of thyroxine and growth hormone on longitudinal bone growth in the hypophysectomized rat. Acta Endocrinol (Kbh) 74: 24–40
Timpl R (1976) Immunological studies on collagen. In: Ramachandran GN, Reddi AH (eds) Biochemistry of collagen. Plenum Press, New York London, pp 319–375
Timpl R, Wick G, Gay S (1977) Antibodies to distinct types of collagen und procollagen and their application in immunohistology. J Immunol Methods 18: 165–182
Tkacz JS, Lampen JO (1975) Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf liver microsomes. Biochem Biophys Res Commun 65: 248–257
Toole BP, Lowther DA (1968) Dermatan sulfate-protein: isolation from and interaction with collagen. Arch Biochem Biophys 128: 567–578
Trang LE, Granström E, Lövgren O (1977) Levels of prostaglandins F2a and E2 and Thromboxane B2 in joint fluid in rheumatoid arthritis. Scand J Rheumatol 6: 151–154
Traub W, Piez KA (1971) The chemistry and structure of collagen. Adv Protein Chem 25: 243–352
Trelstad RL (1974) Human aorta collagens: evidence for 3 distinct species. Biochem Biophys Res Commun 57: 717–732
Trelstad RL, Lawley KR (1977) Isolation and initial characterization of human basement membrans collagens. Biochem Biophys Res Commun 76: 376–384
Trelstad RL, Catanese VM, Rubind DF (1976) Collagen fractionation: separation of native types I, II and III by differential precipitation. An Biochem 71: 114–118
Trelstad RL, Rubind D, Gross J (1977) Osteogenesis imperfecta congenita - Evidence for a generalized molecular disorder of collagen. Lab Invest 36: 501–508
Trnavsky K (1974) Some effect of antiinflammatory drugs on connective tissue metabolism. In: Scherrer RA, Whitehouse MW (eds) Antiinflammatory agents, medicinal chemistry, vol 13–11. Academic Press, New York San Francisco London, pp 303 - 326
Tuderman L, Kuutti ER, Kivirikko KI (1975) Radioimmunoassay for human and chick prolyl hydroxylases. Eur J Biochem 60: 399–405
Tuderman L, Myllyllä R, Kivirikko KI ( 1977 a) Mechanism of the prolyl hydroxylase reaction. 1. Role of Co-substrates. Eur J Biochem 80: 341–348
Tuderman L, Risteli J, Miettinen TA, Kivirikko KI (1977b) Serum immunreactive prolyl hydroxylase in liver disease. Eur J Clin Invest 7: 5537–5541
Uitto J (1971) Collagen biosynthesis in human skin. A review with emphasis on scleroderma. Ann Clin Res 3: 250–258
Uitto J, Lichtenstein JR (1976) Defects in the biochemistry of collagen in diseases of connective tissue. J Invest Dermatol 66: 59–79
Uitto J, Lindy S, Rokkanen P, Vainio K (1970) Increased protokollagen prolin hydroxylase activity in synovial tissue in rheumatoid arthritis. Clin Chim Acta 30: 741–744
Uitto J, Ohlenschlager K, Lorenzen IB (1971) Solubility of skin collagen in normal human subjects in the patients with generalized scleroderma. Clin Chim Acta 31: 13–18
Uitto J, Lindy S, Turfo H, Vainio K (1972b) Collagen biosynthesis in rheumatoid synovial tissue.J Lab Clin Med 79: 960–971
Underhill C, Dorfman A (1978) The role of hyaluronic acid in intracellular adhesion of cultured mouse cells. Exp Cell Res 117: 155–164
Underhill CB, Keller JN (1975) A transformation dependent difference in the heparan sulfate associated with the cell surface. Biochem Biophys Res Commun 63: 448–454
Unkeless JC, Gordon C, Reich E (1974) Secretion of plasminogen activator by stimulated mecrophages. J Exp Med 139: 834–850
Usui J, Kanke J, Mori J (1977) Effects of gonadal hormones on hyaluronic acid content in malemouse skin. Endocrinol Jpn 24: 399–402
Uthne K, Spencer HM, Arnold W (1978) Regulation of somatomedin-A in the rat, p 54 ( Abstr). International Symposium on Somatomedins and Growth, Milano
Vaes D (1972) Inhibitory actions of calcitonin on resorbing bone explants in culture and on their release of lysosomal hydrolases. J Dent Res 51: 362–366
Vaes G (1968) On the mechanism of bone resorption. The action of parathyroid hormone on the excretion and synthesis of lysosomal enzymes and on the extracellular release of acid by bone cells. J Cell Biol 39: 676–697
Vaes GM, Nichols G Jr (1962) Metabolism of glycine 1-14C by bone in vitro: Effects of hormones and other factors. Endocrinology 70: 890–901
Valavaara M, Heikkinen E, Kulonen E (1968) Effect of hypoplupectony on the incorporation of proline in collagen fractions. Experientia 24: 779–780
Vane JR, Ferreira SH (1978) Inflammation. Springer, Berlin Heidelberg New York
Vane JR, Ferreira SH (1979) Anti-inflammatory drugs. Springer, Berlin Heidelberg New York
Varadi DP (1972) Chemistry and fine structure of elastic fibers from normal adult skin. J Invest Dermatol 59: 238–246
Velo GP, Dunn CJ, Giroud JP, Timsit J, Willoughby DA (1973) Distribution of prostaglandins in inflammatory exudate. J Pathol 111: 149–158
Venn M (1979) Variation of chemical composition with age in human femoral head cartilage, (in press)
Venn M, Maroudas A (1977) Chemical composition and swelling of normal and osteoarthritic femoral head cartilage. I. Chemical composition. Ann Rheum Dis 36: 121–129
Vogel A, Holbrook KA, Steinmann B, Gitzelmann R, Byers PH (1979) Abnormal collagen fibril structure in the gravis form (type I) of the Ehlers-Danlos-syndrome. Lab Invest 40: 201–206
Vogel HG (1973) Connective tissue and ageing. Excerpta Medica, Amsterdam
Vuorio E (1977) Rheumatoid disease in cultured human synovial cells. Scand J Clin Lab Invest [Suppl149] 37: 1–72
Vuust J (1975) Procollagen biosynthesis by embryonic chick bone polysomes. Estimation of the relative numbers of active pro-a-1 and pro-a-2 messenger ribonucleic acids. Eur J Biochem 60: 41–50
Wacker A, Ishimoto M, Chandra P (1967) Spezifische und unspezifische Hemmung der zellfreien Proteinsynthese mit Polyanionen. Z Naturforsch [B] 22: 414–117
Wagner O (1976) Immunopathogenic mechanism in rheumatoid diseases with special reference to IgM rheumatoid factor. Scand J Rheumatol [Suppl 12], 5: 67–76
Waite M, Sisson P (1973) Solubilization by heparin of the phospholipase Ax from the plasma membranes of rat liver. J Biol Chem 248: 7201–7206
Waldmann AA, Goldstein J (1973b) Rabbit reticulocyte ribosomes and krebs-ascites supernatant: A mixed system dependent upon added mRNA. Biochim Biophys Acta 331: 243–250
Waldmann AA, Marx G, Goldstein J (1974) Heparin as inhibitor of mammalian protein synthesis. II. Degree of sulfation; related sulfated mucopolysaccharides. Biochim Biophys Acta 343: 324–329
Waldmann AA, Marx G, Goldstein J (1975) Isolation of rabbit reticulocyte initiation factors by means of heparin bound to sepharose. Proc Natl Acad Sei USA 72: 2352–2356
Walker P (1969) In: Wright (ed) Lubrication and wear in joints. Sector Publishing, London
Wartiovaara J, Leivo I, Virtanen I, Vaheri A, Graham CF (1978) Appearance of fibronectin during differentiation of mouse teratocarcinoma in vitro. Nature 272: 355–356
Wegelius O, Pasternack A (1976) Amyloidosis. Proc. of the 5th Sigrid Insulins Foundation Symposium, Helsinki, 1974. Academic Press, London New York
Weis-Fogh T, Anderson SO (1970) New molecular model for the long-range elasticity of elastin. Nature 227: 718–721
Weiss J, Leibovidu SJ, Hunter JA, Cawley MI (1974) Abnormalities in rheumatoid synovial collagen: studies on synovial polymeric collagens ( PC) from normal individuals and patients with rheumatoid and other arthropathies. Ann Rheum Dis 33: 404
Weiss J, Shuttleworth CA, Brown R, Sedowfia K, Baildan A, Hunter JAA (1975) Occurrence of type III collagen in inflamed synovial membranes: A comparison between non-rheumatoid, rheumatoid and normal synovial collagens. Biochem Biophys Res Commun 65: 907–912
Weissmann G, Dukor P, Zurier RB (1971a) Effect of cyclic AMP on release of lysosomal enzymes from phagocytes. Nature 231: 131–135
Weissmann G, Zurier RB, Spieler PJ, Goldstein IM (1971b) Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles. J Exp Med 134: 149–165
Welgus HG, Stricklin GP, Eisen AZ, Bauer EA, Cooney RV, Jeffrey J J (1979) A specific inhibitor of vertebrale collagenase produced by human skin fibroblasts. J Biol Chem 254: 1938–1943
Weller DL, Morgan RS (1967 a) Extraction of high molecular weight complexes of protein from 50 S ribosomes. Biochim Biophys Acta 553–561
Weller DL, Morgan RS (1967b) A new method for preparing ribosomal ribonucleic acid. Biochemistry 6: 983–988
Werb Z, Gordon S (1975) Secretion of specific collagenase by stimulated macrophages. J Exp Med 142: 346–360
Werb Z, Reynolds JJ (1974) Stimulation by endocytosis of the secretion of collagenase and neutral proteinases from rabbit synovia fibroblasts. J Exp Med 140: 1482–1497
Werb Z, Burgleigh MC, Barrett AJ, Storkey PM (1974) The interaction of a2-macroglobulin with proteinases: binding and inhibiting of mammalian collagenases and other metal proteinases. Biochem J 139: 359 - 368
Werb Z, Mainardi CL, Vater CA, Harris ED Jr (1977) Endogeneous activation of collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator. N Engl J Med 296: 1017-1023
Westermark B, Wasteson A (1975) The response of cultured human normal glial cells to growthn factors. Adv Metab Disord 8: 85–100
Westermark P, Natvig JB, Anders RS, Sletten K, Husby G (1976) Coexistence of protein AA and immunoglobulin light-chain fragments in amyloid fibrils. Scand J Immunol 5: 31–36
Whitehouse MW (1965) Some biochemical and pharmacological properties of anti-inflammatory drugs. Prog Drug Res 8: 323–429
Whitehouse MW (1978) Some chemical aspects of inflammation: A brief overview. Aust NZJ Med [Suppl 1] 8: 89–93
Wiebkin OW, Muir H (1975) Influence of the cells on the pericellular environment. Philos Trans R Soc Lond [Biol] 271: 283–291
Wiebkin OW, Hardingham TE, Muir H (1974) The interactions of proteoglycans and hyaluronic acid on the effect of hyaluronic acid on proteoglycan synthesis by chondrocytes of adult cartilage. In: Burleigh PMC, Poole AR (eds) Dynamics of connective tissue macromolecules. North- Holland, Amsterdem, pp 81–98
Wiestner M, Krieg T, Hörlein D, Glanville RW, Fietzek P, Müller PK (1979) Inhibiting effect of procollagen peptides on collagen biosynthesis in fibroblast cultures. J Biol Chem 254: 7016–7023
Willoughby DA, Giroud JP, Di Rosa M, Velo GP (1973) The control of the inflammatory response with special reference to the prostaglandins. In: Kohn RH, Lands WEM (eds) Prostaglandins and cyclic AMP: Biological actions and clinical applications. Academic Press, New York, pp 187 - 206
Winkel P, Juhl E, Tygstrup N (1976) Copenhagen Study Group of for Liver Diseases (CSL): The clinical significance of classification of cirrhosis: A comparison between conventional criteria and numerical taxonomy. Scand J Gastroenterol 11: 33–40
Woda BA (1976) Immune complexes in rheumatic diseases. Lancet 2: 859
Wohlgemuth B (1969) Autoradiographischer Nachweis Hylaseresistenter Mucopolysaccharide bei der Thioacetamid-induzierten Leberzirrhose. Acta Hepatosplenol 16: 8–11
Wolinsky H (1973) Effects of estrogen treatment on the oophorectomized female rat aorta. Proc Soc Exp Biol Med 144: 864–867
Wooley DE, Evanson JM (1977) Collagenase and its natural inhibitors in relation to the rheumatoid joint. Connect Tissue Res 5: 31–35
Wooley DE, Lindberg KA, Glanville RW, Evanson JM (1975) Action of rheumatoid synovial collagenase on cartilage collagen. Different susceptibilities of cartilage and tendon collagen to collage-nase attack. Eur J Biochem 50: 437–4144
Wooley DE, Roberts DR, Evansson JM (1976) Small molecular weight ß1 serum protein which specifically inhibits human collagenases. Nature 261: 325 - 327
Wooley DE, Crossley MJ, Evanson JM (1977) Collagenase at sites of cartilage erosion in the rheumatoid joint. Arthritis Rheum 20: 1231–1239
Wyk JJ van, Underwood LE, Hintz RL, Clemmons DR, Viona SJ, Weaver RP (1974) The somatomedins: a family of insulin like hormones under growth hormone control. In: Greep RO (ed) Recent progress in hormone research, vol 30. Academic Press, New York, pp 259–318
Wyk J J van, Underwood LB, Baseman JB, Hintz RL, Clemmons DR, Marshall RN (1975) Explorations of the insulin-like and growth-promoting properties of somatomedin by membrane receptor assays. Adv Metab Disord 8: 127–150
Wyk JJ van, Svaboda ME, Underwood LE (1980) Evidence from radioligand assays that SM-C and IGF-I are similar to each other. J Clin Endocrinol Metab 50: 206–208
Yalow RS, Hall K, Luft R (1975) Radioimmunoassay of somatomedin B. Adv Metab Disord 8: 73–83
Yamada KM, Olden K (1978) Fibronectins - adhesive glycoproteins of cell surface and blood. Nature 275: 179 - 184
Yamamoto K, Terayama H (1973) Comparison of cell coat acid mucopolysaccharides of normal liver and various ascites hepatoma cells. Cancer Res 33: 2257 - 2264
Yang S-L, Okamura H, Beer AE (1973) The effect of estrogen on collagen synthesis at the site of a skin autograft. Am J Obstet Gynecol 116: 694 - 697
Yaron M, Yaron I, Wiletzki C, Zor U (1978) Interrelationship between stimulation of prostaglandin E and hyaluronate production by poly ( I), poly (c) and interferon in synovial fibroblasts culture. Arthritis Rheum 21: 694-698
Yonemasu K, Stroud RN, Niedermeier W, Butler WT (1971) Chemical studies on C lqu: a modulator of immunoglobulin biology. Biochem Biophys Res Commun 43: 1388 - 1394
Yoshikawa M, Fujita T, Orimo H, Ohata M, Okano K (1974) Endocrine factors in the aging of bone. In: Otaka Y (ed) Biochemistry and pathology of connective tissue. Thieme, Stuttgart, pp 127–138
Zapf J, Mader M, Waldvogel M (1975) Specific binding of non-suppressible insulin-like activity to chicken embryo fibroblasts and to a solubilized fibroblast receptor. Arch Biochem Biophys 168: 630–637
Zingg AE, Froesch ER (1973) Effects of partially purified preparations with nonsuppressible insulinlike activity ( NSILA-s) on sulfate incorporation into rat and chicken cartilage. Diabetologia 9: 472–476
Zurier RB, Weissmann G, Hoffstein S, Tai HH (1974) Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. J Clin Invest 53: 297-309
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Greiling, H., Gressner, A., Kleesiek, K. (1983). Pathobiochemie und Pathophysiologie des Bindegewebes. In: Bach, G.L., et al. Rheumatologie A. Handbuch der inneren Medizin, vol 6 / 2 / A. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68647-4_2
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